Mary Ellen McCann, MD, MPH
Senior Associate in Perioperative Anesthesia, Department of Anesthesiology, Critical Care and Pain Medicine
Professor of Clinical Anaesthesia, Harvard Medical School
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Mary Ellen McCann, MD, MPH
Senior Associate in Perioperative Anesthesia, Department of Anesthesiology, Critical Care and Pain Medicine
Professor of Clinical Anaesthesia, Harvard Medical School
Medical Services
Languages
English
Education
Medical School
Boston University School of Medicine
1981
Boston
MA
Internship
Pediatrics
Massachusetts General Hospital
1982
Boston
MA
Residency
Pediatrics
Massachusetts General Hospital
1984
Boston
MA
Residency
Anesthesia
Massachusetts General Hospital
1987
Boston
MA
Fellowship
Pediatrics
Massachusetts General Hospital
1988
Boston
MA
Certifications
American Board of Anesthesiology (Pediatric Anesthesiology)
Publications
Short-term Outcomes in Infants after General Anesthesia with Low-dose Sevoflurane/Dexmedetomidine/Remifentanil versus Standard-dose Sevoflurane (the TREX Trial). View Abstract
Neurodevelopmental Outcomes After Multiple General Anaesthetic Exposure Before Five Years Of Age - A Cohort Study. View Abstract
Neurodevelopmental Outcomes after Multiple General Anesthetic Exposures before 5 Years of Age: A Cohort Study. View Abstract
Acute Dystonic Reaction After Propofol Administration: A Pediatric Case Report. View Abstract
Sevoflurane anaesthesia induces cognitive impairment in young mice through sequential tau phosphorylation. View Abstract
Comparer Pommes et Oranges: Perils of Translating Rodent Studies to Human Outcomes. View Abstract
Anesthesia and Developing Brains: Unanswered Questions and Proposed Paths Forward. View Abstract
Performing Multiple Posterior Spinal Fusions in 1 Day: A Comparison of Perioperative Outcomes Between Morning and Afternoon Cases. View Abstract
Liposomal Bupivacaine. View Abstract
Prospectively assessed neurodevelopmental outcomes in studies of anaesthetic neurotoxicity in children: a systematic review and meta-analysis. View Abstract
The Unspoken Question! View Abstract
Is Anesthesia Bad for the Brain? Current Knowledge on the Impact of Anesthetics on the Developing Brain. View Abstract
Implementing a Multidisciplinary Clinical Pathway Can Reduce the Deep Surgical Site Infection Rate After Posterior Spinal Fusion in High-Risk Patients. View Abstract
Does general anesthesia affect neurodevelopment in infants and children? View Abstract
Beyond Anesthesia Toxicity: Anesthetic Considerations to Lessen the Risk of Neonatal Neurological Injury. View Abstract
Adverse Perioperative Events in Children with Complex Congenital Heart Disease Undergoing Operative Scoliosis Repair in the Contemporary Era. View Abstract
Neurodevelopmental outcome at 5 years of age after general anaesthesia or awake-regional anaesthesia in infancy (GAS): an international, multicentre, randomised, controlled equivalence trial. View Abstract
Implementing a Multidisciplinary Clinical Pathway Can Reduce the Deep Surgical Site Infection Rate After Posterior Spinal Fusion in High-Risk Patients. View Abstract
An open label pilot study of a dexmedetomidine-remifentanil-caudal anesthetic for infant lower abdominal/lower extremity surgery: The T REX pilot study. View Abstract
Tranexamic Acid Is Efficacious at Decreasing the Rate of Blood Loss in Adolescent Scoliosis Surgery: A Randomized Placebo-Controlled Trial. View Abstract
Enrollment challenges in multicenter, international studies: The example of the GAS trial. View Abstract
Anesthesia and the developing brain: A way forward for laboratory and clinical research. View Abstract
Estimating pediatric general anesthesia exposure: Quantifying duration and risk. View Abstract
Surgical practice and outcome in 711 neonates and infants undergoing hernia repair in a large multicenter RCT: Secondary results from the GAS Study. View Abstract
Differences in Blood Pressure in Infants After General Anesthesia Compared to Awake Regional Anesthesia (GAS Study-A Prospective Randomized Trial). View Abstract
Warnings, uncertainty, and clinical practice. View Abstract
Perioperative factors influencing neurocognitive outcomes in infants. View Abstract
Anesthesia, brain changes, and behavior: Insights from neural systems biology. View Abstract
Current thinking regarding potential neurotoxicity of general anesthesia in infants. View Abstract
Summary of the Update Session on Clinical Neurotoxicity Studies. View Abstract
Outcomes in the trial registry should match those in the protocol - Authors' reply. View Abstract
The GAS trial - Authors' reply. View Abstract
Neurodevelopmental outcome at 2 years of age after general anaesthesia and awake-regional anaesthesia in infancy (GAS): an international multicentre, randomised controlled trial. View Abstract
A Phase 1, Dose-escalation, Double-blind, Block-randomized, Controlled Trial of Safety and Efficacy of Neosaxitoxin Alone and in Combination with 0.2% Bupivacaine, with and without Epinephrine, for Cutaneous Anesthesia. View Abstract
Predictors of Failure of Awake Regional Anesthesia for Neonatal Hernia Repair: Data from the General Anesthesia Compared to Spinal Anesthesia Study--Comparing Apnea and Neurodevelopmental Outcomes. View Abstract
Apnea after Awake Regional and General Anesthesia in Infants: The General Anesthesia Compared to Spinal Anesthesia Study--Comparing Apnea and Neurodevelopmental Outcomes, a Randomized Controlled Trial. View Abstract
Anesthesia and the developing brain: a way forward for clinical research. View Abstract
Progress in anesthesia and management of the newborn surgical patient. View Abstract
Infantile postoperative encephalopathy: perioperative factors as a cause for concern. View Abstract
Beyond survival; influences of blood pressure, cerebral perfusion and anesthesia on neurodevelopment. View Abstract
A case of cerebrospinal fluid leak in an infant after spinal anesthesia. View Abstract
Perioperative central nervous system injury in neonates. View Abstract
General anesthetics in pediatric anesthesia: influences on the developing brain. View Abstract
Anesthetic neurotoxicity in babies. View Abstract
Postoperative adrenal crisis in an adolescent with Loeys-Dietz syndrome and undiagnosed adrenoleukodystrophy. View Abstract
Anaesthesia for urgent and emergency surgery. View Abstract
Is anesthesia bad for the newborn brain? View Abstract
Clinical research approaches to studying pediatric anesthetic neurotoxicity. View Abstract
Pediatric section of the 3rd Edition ASA RECOMMENDATIONS FOR INFECTION CONTROL FOR THE PRACTICE OF ANESTHESIA View Abstract
Is Anesthesia Bad for the Newborn Brain? View Abstract
Department of Anesthesia,Perioperative and Pain Medicine Infection Control Guidelines, 2003,2008,2009 View Abstract
Clinical Pearls-VEPTR and Growing Rods View Abstract
Neuromonitoring View Abstract
Hand Hygiene and Infection Control NET learning View Abstract
Clinical Approaches to studying Pediatric Anesthetic Neurotoxicity View Abstract
Prediction of wheat chemical and physical characteristics and nutritive value by near-infrared reflectance spectroscopy. View Abstract
Anesthesia and outcome after neonatal surgery: the role for randomized trials. View Abstract
Clinical Pearls-VEPTR and Growing Rods View Abstract
Stable plasma concentrations of unbound ropivacaine during postoperative epidural infusion for 24-72 hours in children. View Abstract
Safe Care in the Operating Room – An Anesthesiologist Perspective-a 15 minute long DVD produced and written by Mary Ellen McCann and Beth Norton View Abstract
Is Nitrous Oxide a safe anesthetic View Abstract
Enduring Web based Learning for the Society of Pediatric Anesthesia "Is nitrous oxide a safe anesthetic?" View Abstract
Anesthetic Considerations for Common Procedures in Children View Abstract
The Musculoskeletal System and Orthopedic Surgery View Abstract
Anesthesia neurotoxicity in neonates: the need for clinical research. View Abstract
Enduring web-based education materials for the Society of Pediatric Anesthesia "Reflex Sympathetic Dystrophy" View Abstract
Reflex Sympathetic Dystrophy View Abstract
Letter to the Editor
Anesthesia Neurotoxicity in Neonates: The Need for Clinical Research View Abstract
Does repeated exposure to anesthetic drugs lead to neurodevelopmental disabilities? View Abstract
A comparison of radial artery blood pressure determination between the Vasotrac device and invasive arterial blood pressure monitoring in adolescents undergoing scoliosis surgery. View Abstract
Topiramate and metabolic acidosis: a case series and review of the literature. View Abstract
Bioterrorism and children: unique concerns with infection control and vaccination. View Abstract
Self-mutilation in young children following brachial plexus birth injury. View Abstract
Self-Mutilation in Young Children Following Neonatal Brachial Plexus Injury View Abstract
Accuracy of Radial Artery Blood Pressure Determination in Children Undergoing Controlled Hypotensive Anesthesia in the Prone Position with the Vasotrac View Abstract
The correlation of bispectral index with endtidal sevoflurane concentration and haemodynamic parameters in preschoolers. View Abstract
The bispectral index and explicit recall during the intraoperative wake-up test for scoliosis surgery. View Abstract
Neuroanesthesia. Innovative techniques and monitoring. View Abstract
The pharmacokinetics of epidural ropivacaine in infants and young children. View Abstract
The differences in the bispectral index between infants and children during emergence from anesthesia after circumcision surgery. View Abstract
The management of preoperative anxiety in children: an update. View Abstract
BIS Index as a Pharmacodynamic Endpoint in Preschoolers Undergoing Tonsillectomy and Adenoidectomy View Abstract
Postoperative Nausea and Vomiting. Chapter 9 in Section 8, Pediatric Anesthesia, in Harvard Electronic Anesthesia Library. Bailin MT (ed.) View Abstract
Pharmacokinetics of Lumbar Epidural Ropivacaine in Infants and Toddlers, Ages 3 Months to 48 Months View Abstract
Electrocardiographic inscription of diaphragmatic contractions during anaesthesia. View Abstract
Pharmacokinetics of Lumbar Epidural Ropivacaine in Children and Adolescents View Abstract
Electrocardiographic inscription of diaphragmatic contractions during anesthesia View Abstract
In Anesthetized Children during the administration of lactated Ringer’s and 5% Dextrose in lactated Ringers View Abstract
Case No 12 View Abstract
Case No.12 View Abstract