Margaret Kenna, MD, MPH, FACS, FAAP
Otolaryngologist, Department of Otolaryngology and Communication Enhancement; Director of Clinical Research, Department of Otolaryngology and Communication Enhancement
Professor of Otolaryngology, Harvard Medical School
Image
Margaret Kenna, MD, MPH, FACS, FAAP
Otolaryngologist, Department of Otolaryngology and Communication Enhancement; Director of Clinical Research, Department of Otolaryngology and Communication Enhancement
Professor of Otolaryngology, Harvard Medical School
Medical Services
Languages
English
Education
Medical School
Boston University School of Medicine
1979
Boston
MA
Internship
University Hospital of Arkansas
1980
Little Rock
AR
Residency
University Hospital of Arkansas
1983
Little Rock
AR
Fellowship
Children's Hospital of Pittsburgh
1984
Pittsburgh
PA
Graduate School
MPH
Harvard School of Public Health
2005
Boston
MA
Certifications
American Board of Otolaryngology (General)
Professional History
Margaret A. Kenna, MD, MPH, is a graduate of the Univ. of Pennsylvania (1974) and Boston University School of Medicine (1979). She completed her residency training in Otolaryngology-Head and Neck Surgery at the Univ. of Arkansas for Medical Sciences (1983) and fellowship in Pediatric Otolaryngology at the Children’s Hospital of Pittsburgh. Before coming to Boston, she was on the faculty at Children’s Hospital of Pittsburgh and Yale University School of Medicine.
Dr. Kenna has been on the Otolaryngology faculty at Boston Children’s Hospital since 1995. She co-founded the Children’s Hospital Boston Cochlear Implant Program, and was its Director from 1995-2003. Since 2003, she has been the Director of Clinical Research in the Dept. of Otolaryngology, Boston Children’s Hospital, and is Director of the Hearing Loss Program. She completed a Master’s in Public Health degree (MPH) in the area of Clinical Effectiveness at the Harvard School of Public Health in 2005.
Dr. Kenna serves as an expert for the Department of Otolaryngology for Boston Children's Hospital Precision Medicine Service. For more information about the Precision Medicine Service please visit bostonchildrens.org/precisionmed.
Publications
ClinGen recuration of hearing loss-associated genes demonstrates significant changes in gene-disease validity over time. View Abstract
Hospital-wide access to genomic data advanced pediatric rare disease research and clinical outcomes. View Abstract
Management of Prenatal Expanded Genetic Carrier Screening Results for Autosomal Recessive Sensorineural Hearing Loss. View Abstract
Microbial DNA extraction method for avian feces and preen oil from diverse species. View Abstract
Chromosomal structural rearrangements implicate long non-coding RNAs in rare germline disorders. View Abstract
Rare germline disorders implicate long non-coding RNAs disrupted by chromosomal structural rearrangements. View Abstract
Ciliopathy patient variants reveal organelle-specific functions for TUBB4B in axonemal microtubules. View Abstract
PKHD1L1, a gene involved in the stereocilia coat, causes autosomal recessive nonsyndromic hearing loss. View Abstract
PKHD1L1, A Gene Involved in the Stereocilia Coat, Causes Autosomal Recessive Nonsyndromic Hearing Loss. View Abstract
Models of Classroom Assessment for Course-Based Research Experiences. View Abstract
Vestibular Preservation in Pediatric Cochlear Implantation. View Abstract
Programming Levels and Speech Perception in Pediatric Cochlear Implant Recipients With Enlarged Vestibular Aqueduct or GJB2 Mutation. View Abstract
Newborn Hearing Screening Results in Patients with Enlarged Vestibular Aqueduct. View Abstract
Exome Sequencing Expands the Genetic Diagnostic Spectrum for Pediatric Hearing Loss. View Abstract
Congenital Cytomegalovirus Screening in Massachusetts Birth Hospitals: A Statewide Survey. View Abstract
Otolaryngologic Manifestations of Trisomy 13 and Trisomy 18 in Pediatric Patients. View Abstract
Characterization of a possible founder synonymous variant in TECTA in multiple individuals with autosomal recessive hearing loss. View Abstract
Genetic testing for pediatric hearing loss: no time to waste. View Abstract
In Response to, "Is revision of Cochlear Implants Infrequent?" View Abstract
Hearing Stability in Patients With Unilateral Hearing Loss Due to Congenital CMV. View Abstract
Pain at the Cochlear Implant Site Requiring Device Removal in Pediatric Patients. View Abstract
Evaluation of copy number variants for genetic hearing loss: a review of current approaches and recent findings. View Abstract
Peripheral Vestibular Dysfunction Is a Common Occurrence in Children With Non-syndromic and Syndromic Genetic Hearing Loss. View Abstract
Comprehensive medical evaluation of pediatric bilateral sensorineural hearing loss. View Abstract
Hearing Aid Use in Children With Unilateral Hearing Loss: A Randomized Crossover Clinical Trial. View Abstract
Neuroimaging in Kabuki syndrome and another KMT2D-related disorder. View Abstract
Hiding in plain sight: genetic deaf-blindness is not always Usher syndrome. View Abstract
Pediatric Bilateral Sensorineural Hearing Loss: Minimum Test Battery and Referral Criteria for Cochlear Implant Candidacy Evaluation. View Abstract
Disease-specific ACMG/AMP guidelines improve sequence variant interpretation for hearing loss. View Abstract
Biallelic variants in KARS1 are associated with neurodevelopmental disorders and hearing loss recapitulated by the knockout zebrafish. View Abstract
Audiologic Phenotype and Progression in Pediatric STRC-Related Autosomal Recessive Hearing Loss. View Abstract
Review of Hearing Loss in Children-Reply. View Abstract
Just Do It-Everyone Should Follow the Guidelines. View Abstract
Incidence, Time Course, and Implications of Electrode Abnormalities in Pediatric Cochlear Implant Recipients. View Abstract
Dark-adapted threshold and electroretinogram for diagnosis of Usher syndrome. View Abstract
A synonymous variant in MYO15A enriched in the Ashkenazi Jewish population causes autosomal recessive hearing loss due to abnormal splicing. View Abstract
Hearing Loss in Children: A Review. View Abstract
Does Ibuprofen Increase Bleed Risk for Pediatric Tonsillectomy? View Abstract
Women in Otolaryngology: Experiences of Being Female in the Specialty. View Abstract
Validation of a Parent Proxy Quality-of-Life Measure for Young Children With Hearing Loss. View Abstract
Genomic diversity of bacteriophages infecting Microbacterium spp. View Abstract
Genetics of pediatric hearing loss: A functional perspective. View Abstract
Association of Blood Type With Postsurgical Mucosal Bleeding in Pediatric Patients Undergoing Tonsillectomy With or Without Adenoidectomy. View Abstract
Perspective on the Development of a Large-Scale Clinical Data Repository for Pediatric Hearing Research. View Abstract
Preclinical testing of AAV9-PHP.B for transgene expression in the non-human primate cochlea. View Abstract
Torticollis in children with enlarged vestibular aqueducts. View Abstract
Correction: ClinGen expert clinical validity curation of 164 hearing loss gene-disease pairs. View Abstract
Consensus interpretation of the p.Met34Thr and p.Val37Ile variants in GJB2 by the ClinGen Hearing Loss Expert Panel. View Abstract
Genome Sequences of Six Cluster N Mycobacteriophages, Kevin1, Nenae, Parmesanjohn, ShrimpFriedEgg, Smurph, and SpongeBob, Isolated on Mycobacterium smegmatis mc2155. View Abstract
A novel missense mutation in TFAP2B associated with Char syndrome and central diabetes insipidus. View Abstract
ClinGen expert clinical validity curation of 164 hearing loss gene-disease pairs. View Abstract
Gene Transfer with AAV9-PHP.B Rescues Hearing in a Mouse Model of Usher Syndrome 3A and Transduces Hair Cells in a Non-human Primate. View Abstract
Expert specification of the ACMG/AMP variant interpretation guidelines for genetic hearing loss. View Abstract
Does Clarithromycin Cause Hearing Loss? A 12-Year Review of Clarithromycin Therapy for Nontuberculous Mycobacterial Lymphadenitis in Children. View Abstract
Ambulatory Visits for Otitis Media before and after the Introduction of Pneumococcal Conjugate Vaccination. View Abstract
Postoperative Hearing Loss in a Patient With Crouzon Syndrome: A Case Report. View Abstract
Revision cochlear implant surgery in children: Surgical and audiological outcomes. View Abstract
Validation of a portable hearing assessment tool: Agilis Health Mobile Audiogram. View Abstract
Otolaryngologic Manifestations of Klippel-Feil Syndrome in Children. View Abstract
Enlarged Vestibular Aqueduct and Cochlear Implants: The Effect of Early Counseling on the Length of Time Between Candidacy and Implantation. View Abstract
Eight Genome Sequences of Cluster BE1 Phages That Infect Streptomyces Species. View Abstract
Genome Sequences of Chancellor, Mitti, and Wintermute, Three Subcluster K4 Phages Isolated Using Mycobacterium smegmatis mc2155. View Abstract
Tales of diversity: Genomic and morphological characteristics of forty-six Arthrobacter phages. View Abstract
Neurologic Evaluation in Children With Laryngeal Cleft. View Abstract
Genome Sequences of Mycobacteriophages Jane and Sneeze, New Members of Cluster G. View Abstract
Genome Sequence of Cluster W Mycobacteriophage Taptic. View Abstract
Prophage-mediated defence against viral attack and viral counter-defence. View Abstract
Acute Otitis Media - The Long and the Short of It. View Abstract
Periodic Fever, Aphthosis, Pharyngitis, and Adenitis Syndrome: Analysis of Patients From Two Geographic Areas. View Abstract
Hearing loss associated with enlarged vestibular aqueduct and zero or one mutant allele of SLC26A4. View Abstract
International Pediatric Otolaryngology Group (IPOG) consensus recommendations: Hearing loss in the pediatric patient. View Abstract
Risk Factors for Hearing Loss in Patients with Cystic Fibrosis. View Abstract
Atypical patterns of segregation of familial enlargement of the vestibular aqueduct. View Abstract
Acquired Hearing Loss in Children. View Abstract
The Child with Hearing Loss. View Abstract
Peripheral vestibular loss detected in pediatric patients using a smartphone-based test of the subjective visual vertical. View Abstract
The Public Health Impact of Pediatric Deep Neck Space Infections. View Abstract
Subjective visual vertical testing in children and adolescents. View Abstract
What is the best non-codeine postadenotonsillectomy pain management for children? View Abstract
A121: in search of infectious triggers of periodic Fever, aphthous stomatitis, pharyngitis and adenitis syndrome. View Abstract
Use of SLC26A4 mutation testing for unilateral enlargement of the vestibular aqueduct. View Abstract
3 µm CW lasers for myringotomy and microsurgery. View Abstract
Pediatric sudden sensorineural hearing loss: diagnosed causes and response to intervention. View Abstract
Long-term surgical outcomes of adenotonsillectomy for PFAPA syndrome. View Abstract
Frequent association of cochlear nerve canal stenosis with pediatric sensorineural hearing loss. View Abstract
Prognosis tool based on a modified children's implant profile for use in pediatric cochlear implant candidacy evaluation. View Abstract
Genome-wide SNP genotyping identifies the Stereocilin (STRC) gene as a major contributor to pediatric bilateral sensorineural hearing impairment. View Abstract
Retinal disease course in Usher syndrome 1B due to MYO7A mutations. View Abstract
Clinical experience in diagnosis and management of superior semicircular canal dehiscence in children. View Abstract
Enlarged vestibular aqueduct: review of controversial aspects. View Abstract
Comparison of postoperative pain in pediatric patients undergoing coblation tonsillectomy versus cautery tonsillectomy. View Abstract
Histopathologic investigation of the dimensions of the cochlear nerve canal in normal temporal bones. View Abstract
Temporal bone abnormalities in children with GJB2 mutations. View Abstract
Is computed tomography (CT) or magnetic resonance imaging (MRI) more useful in the evaluation of pediatric sensorineural hearing loss? View Abstract
Not a "sound" decision: is cochlear implantation always the best choice? View Abstract
High-throughput detection of mutations responsible for childhood hearing loss using resequencing microarrays. View Abstract
Posterior semicircular canal dehiscence: first reported case series. View Abstract
Audiologic phenotype and progression in GJB2 (Connexin 26) hearing loss. View Abstract
Sensorineural hearing loss in patients with cystic fibrosis. View Abstract
Distinct and novel SLC26A4/Pendrin mutations in Chinese and U.S. patients with nonsyndromic hearing loss. View Abstract
Disturbance of vestibular function attributable to cochlear implantation in children. View Abstract
Assessment of saccular function in children with sensorineural hearing loss. View Abstract
Delineating the hearing loss in children with enlarged vestibular aqueduct. View Abstract
Use of a preoperative bleeding questionnaire in pediatric patients who undergo adenotonsillectomy. View Abstract
Phosphorylcholine-coated antibiotic tympanostomy tubes: are post-tube placement complications reduced? View Abstract
Music to your ears: is it a good thing? View Abstract
Effect of adenotonsillectomy in PFAPA syndrome. View Abstract
Additional clinical manifestations in children with sensorineural hearing loss and biallelic GJB2 mutations: who should be offered GJB2 testing? View Abstract
A multicenter study of the frequency and distribution of GJB2 and GJB6 mutations in a large North American cohort. View Abstract
Anomalies of the middle and inner ear. View Abstract
The nuclear envelope and spindle pole body-associated Mps3 protein bind telomere regulators and function in telomere clustering. View Abstract
Intersection between the regulators of sister chromatid cohesion establishment and maintenance in budding yeast indicates a multi-step mechanism. View Abstract
Pediatric adenoidectomy: what is the effect of obstructive symptoms on the likelihood of future surgery? View Abstract
The use of perioperative antibiotics in tonsillectomy: does it decrease morbidity? View Abstract
GJB2 mutations and degree of hearing loss: a multicenter study. View Abstract
Pediatric facial nerve paralysis: patients, management and outcomes. View Abstract
Otitis media and the new guidelines. View Abstract
Combined microtia and aural atresia: issues in cochlear implantation. View Abstract
Medical management of childhood hearing loss. View Abstract
The spindle pole body assembly component mps3p/nep98p functions in sister chromatid cohesion. View Abstract
Clinical practice guideline: Otitis media with effusion. View Abstract
Human EFO1p exhibits acetyltransferase activity and is a unique combination of linker histone and Ctf7p/Eco1p chromatid cohesion establishment domains. View Abstract
Extraesophageal reflux in pediatric patients with upper respiratory symptoms. View Abstract
Use of a multiplex PCR/sequencing strategy to detect both connexin 30 (GJB6) 342 kb deletion and connexin 26 (GJB2) mutations in cases of childhood deafness. View Abstract
Utility of tonsillectomy in 2 patients with the syndrome of periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis. View Abstract
Mechanical link between cohesion establishment and DNA replication: Ctf7p/Eco1p, a cohesion establishment factor, associates with three different replication factor C complexes. View Abstract
The presentation and management of nasal dermoid: a 30-year experience. View Abstract
Neonatal hearing screening. View Abstract
Effectiveness of sequencing connexin 26 (GJB2) in cases of familial or sporadic childhood deafness referred for molecular diagnostic testing. View Abstract
The role of mitomycin in the prevention and treatment of scar formation in the pediatric aerodigestive tract: friend or foe? View Abstract
Congenital absence of the incus bilaterally without other otologic anomalies: a new case report. View Abstract
Connexin 26 studies in patients with sensorineural hearing loss. View Abstract
Mediastinitis associated with foreign body erosion of the esophagus in children. View Abstract
Craniofacial, temporal bone, and audiologic abnormalities in the spectrum of hemifacial microsomia. View Abstract
The relationship between dental overbite and eustachian tube dysfunction. View Abstract
Airway foreign bodies (FB): a 10-year review. View Abstract
Intraoperative recurrent laryngeal nerve monitoring during video-assisted throracoscopic surgery for patent ductus arteriosus. View Abstract
Otitis media: the otolaryngologist's perspective. View Abstract
Pathology forum: quiz case 1. Diagnosis: posttransplant lymphoproliferative disease (PTLD) of the epiglottis. View Abstract
A phylogenetically conserved NAD+-dependent protein deacetylase activity in the Sir2 protein family. View Abstract
Don't rely on the surgical airway: a case of impossible tracheostomy. View Abstract
Cochlear implants and the deaf child: a nursing perspective. View Abstract
Acupressure-acupuncture antiemetic prophylaxis in children undergoing tonsillectomy. View Abstract
Causes of pediatric sensorineural hearing loss: yesterday and today. View Abstract
Necrotizing fasciitis of the pharynx following adenotonsillectomy. View Abstract
Intraneuronal ApoE in human visual cortical areas reflects the staging of Alzheimer disease pathology. View Abstract
Treatment of chronic suppurative otitis media with topical ciprofloxacin. View Abstract
Comparison of spectral gradient acoustic reflectometry and other diagnostic techniques for detection of middle ear effusion in children with middle ear disease. View Abstract
Invading the yeast nucleus: a nuclear localization signal at the C terminus of Ty1 integrase is required for transposition in vivo. View Abstract
Cochlear implantation in children. View Abstract
Yeast N1e3p/Nup170p is required for normal stoichiometry of FG nucleoporins within the nuclear pore complex. View Abstract
In vitro susceptibility of aural isolates of Pseudomonas aeruginosa to commonly used ototopical antibiotics. View Abstract
Therapeutic implications in the treatment of aural Pseudomonas infections based on in vitro susceptibility patterns. View Abstract
Pathologic quiz case 1. Granular cell tumor (GCT) of larynx. View Abstract
Head and neck manifestations of Beckwith-Wiedemann syndrome. View Abstract
Correlation of beta-2 transferrin and middle ear abnormalities in congenital perilymphatic fistula. View Abstract
Consultation with the specialist. Hoarseness. View Abstract
Genetic and physical interactions between Srp1p and nuclear pore complex proteins Nup1p and Nup2p. View Abstract
Treatment of chronic suppurative otitis media. View Abstract
Sensorineural hearing loss from quinolinic acid: a neurotoxin in middle ear effusions. View Abstract
Medical management of chronic suppurative otitis media without cholesteatoma in children--update 1992. View Abstract
Laryngeal cysts: a cause of neonatal airway obstruction. View Abstract
An essential yeast gene with homology to the exonuclease-encoding XRN1/KEM1 gene also encodes a protein with exoribonuclease activity. View Abstract
Adenotonsillectomy for upper airway obstruction carries increased risk in children with a history of prematurity. View Abstract
The effect of gastroesophageal reflux on the pediatric airway. View Abstract
Surgical management of tracheal stenosis in an infant with multiple congenital anomalies: when is baby inoperable? View Abstract
Congenital perilymphatic fistula: an overlooked diagnosis? View Abstract
The structure of a primitive kinetochore. View Abstract
Cis- and trans-acting factors affecting the structure of yeast centromeres. View Abstract
Selective excision of the centromere chromatin complex from Saccharomyces cerevisiae. View Abstract
Foreign bodies in the air and food passages. View Abstract
Refractory torticollis: an uncommon complication of adenotonsillectomy. View Abstract
Cefixime vs. cefaclor in the treatment of acute otitis media in infants and children. View Abstract
Prognostic value of eustachian tube function in pediatric tympanoplasty. View Abstract
Tracheotomy in the preterm infant. View Abstract
Duration of intubation in children with acute epiglottitis. View Abstract
Junctional epidermolysis bullosa of the larynx. View Abstract
Microbiology of chronic suppurative otitis media in children. View Abstract
Complication of acute epiglottitis. View Abstract
Medical management of chronic suppurative otitis media without cholesteatoma in children. View Abstract
Nasal surgery in children with cystic fibrosis: complications and risk management. View Abstract
Consensus: management of the child with a chronic draining ear. View Abstract
Tidal flow measurement in the decision to decannulate the pediatric patient. View Abstract
Transsphenoidal encephalocele. View Abstract
Amplification and elevated expression of c-myc in a chemically induced mouse colon tumor. View Abstract
Effectiveness of hydrotreatment in reducing the toxicity of a coal liquefaction product to juvenile channel catfish. View Abstract
Nasal papillomas and squamous carcinoma. View Abstract
Chronic suppurative otitis media: antimicrobial therapy or surgery? View Abstract
Malignant granular cell tumor of the tongue. View Abstract
Concanavalin A-mediated binding and sphering of human red blood cells by homologous monocytes. View Abstract
Effect of papain on the interaction between human monocytes, erythrocytes, and IgG. View Abstract
Drugs in child psychotherapy. View Abstract
Locations