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Manuela Cernadas, MD
Pulmonologist, Division of Pulmonary Medicine
Assistant Professor of Medicine, Harvard Medical School
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Manuela Cernadas, MD
Pulmonologist, Division of Pulmonary Medicine
Assistant Professor of Medicine, Harvard Medical School
Medical Services
Languages
English
Spanish
Certifications
American Board of Internal Medicine (Adult Pulmonary Critical Care)
Publications
SARS-CoV-2 viral clearance and evolution varies by type and severity of immunodeficiency. View Abstract
SARS-CoV-2 Viral Clearance and Evolution Varies by Extent of Immunodeficiency. View Abstract
Diagnostic Aspirations. View Abstract
Surfactant Protein D Influences Mortality During Abdominal Sepsis by Facilitating Escherichia coli Colonization in the Gut. View Abstract
The effect of elexacaftor/tezacaftor/ivacaftor (ETI) on glycemia in adults with cystic fibrosis. View Abstract
Persistence and Evolution of SARS-CoV-2 in an Immunocompromised Host. View Abstract
CFTR regulates B cell activation and lymphoid follicle development. View Abstract
Macrophage FABP4 is required for neutrophil recruitment and bacterial clearance in Pseudomonas aeruginosa pneumonia. View Abstract
Neutrophil cytoplasts induce TH17 differentiation and skew inflammation toward neutrophilia in severe asthma. View Abstract
ALX receptor ligands define a biochemical endotype for severe asthma. View Abstract
ALX receptor ligands define a biochemical endotype for severe asthma. View Abstract
Natural killer cell-mediated inflammation resolution is disabled in severe asthma. View Abstract
Alternative Macrophage Activation Is Increased in Asthma. View Abstract
Vitamin D3 treatment of vitamin D-insufficient asthmatic patients does not alter immune cell function. View Abstract
Circadian rhythm reprogramming during lung inflammation. View Abstract
Adam8 limits the development of allergic airway inflammation in mice. View Abstract
Integrating murine gene expression studies to understand obstructive lung disease due to chronic inhaled endotoxin. View Abstract
Lipoxin A4 regulates natural killer cell and type 2 innate lymphoid cell activation in asthma. View Abstract
Endothelial cell-fatty acid binding protein 4 promotes angiogenesis: role of stem cell factor/c-kit pathway. View Abstract
Chronic endotoxin exposure produces airflow obstruction and lung dendritic cell expansion. View Abstract
PTPN22.6, a dominant negative isoform of PTPN22 and potential biomarker of rheumatoid arthritis. View Abstract
Cyclooxygenase-2 deficiency leads to intestinal barrier dysfunction and increased mortality during polymicrobial sepsis. View Abstract
It takes a microbiome: commensals, immune regulation, and allergy. View Abstract
NK cells are effectors for resolvin E1 in the timely resolution of allergic airway inflammation. View Abstract
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome. View Abstract
Synovial fibroblasts self-direct multicellular lining architecture and synthetic function in three-dimensional organ culture. View Abstract
Activation state and intracellular trafficking contribute to the repertoire of endogenous glycosphingolipids presented by CD1d [corrected]. View Abstract
Early recycling compartment trafficking of CD1a is essential for its intersection and presentation of lipid antigens. View Abstract
CD1a expression defines an interleukin-12 producing population of human dendritic cells. View Abstract
Resolvin E1 regulates interleukin 23, interferon-gamma and lipoxin A4 to promote the resolution of allergic airway inflammation. View Abstract
Cigarette smoke exposure impairs dendritic cell maturation and T cell proliferation in thoracic lymph nodes of mice. View Abstract
PU.1 regulates cathepsin S expression in professional APCs. View Abstract
New insights into pathways for CD1-mediated antigen presentation. View Abstract
Lysosomal localization of murine CD1d mediated by AP-3 is necessary for NK T cell development. View Abstract
IL-6 production by pulmonary dendritic cells impedes Th1 immune responses. View Abstract
Integrin alpha E(CD103)beta 7 mediates adhesion to intestinal microvascular endothelial cell lines via an E-cadherin-independent interaction. View Abstract
The role of alpha and beta chains in ligand recognition by beta 7 integrins. View Abstract
B7-1 (CD80) and B7-2 (CD86) have complementary roles in mediating allergic pulmonary inflammation and airway hyperresponsiveness. View Abstract
CD23 and allergic pulmonary inflammation: potential role as an inhibitor. View Abstract
Expression of constitutive and inducible nitric oxide synthases in the vascular wall of young and aging rats. View Abstract
Role of nitric oxide-related mechanisms in renal function in ageing rats. View Abstract
Inhibition of T cell costimulation abrogates airway hyperresponsiveness in a murine model. View Abstract
Role of endothelium-related mechanisms in the pathophysiology of renal ischemia/reperfusion in normal rabbits. View Abstract
T cell activation in a murine model of asthma. View Abstract
Role of endothelin in the pathophysiology of renal ischemia-reperfusion in normal rabbits. View Abstract
Aspirin-stimulated nitric oxide production by neutrophils after acute myocardial ischemia in rabbits. View Abstract
Effect of endothelin-1 on neutrophil adhesion to endothelial cells and perfused heart. View Abstract
Renal and systemic effects of aminoacids administered separately: comparison between L-arginine and non-nitric oxide donor aminoacids. View Abstract
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