Lawrence Tsen, MD
Chair, BWH Human Research Committee/Institutional Review Board; Director of Anesthesia, BWH Center for Reproductive Medicine
Associate Professor in Anesthesia, Harvard Medical School
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Lawrence Tsen, MD
Chair, BWH Human Research Committee/Institutional Review Board; Director of Anesthesia, BWH Center for Reproductive Medicine
Associate Professor in Anesthesia, Harvard Medical School
Medical Services
Languages
English
Education
Undergraduate School
Kansas State University
1986
Manhattan
KS
Medical School
University of Kansas School of Medicine
1991
Kansas City
KS
Internship
Transitional
University of Illinois School of Medicine
1992
Chicago
IL
Residency
Anesthesiology
University of Illinois School of Medicine
1995
Chicago
IL
Fellowship
Obstetric Anesthesia
Harvard Medical School
1996
Boston
MA
Certifications
American Board of Anesthesiology (General)
Professional History
Lawrence Tsen, MD is an Associate Professor in Anaesthesia at Harvard Medical School and for the Brigham and Women’s Hospital, he serves as the Director of Anesthesia for the Center for Reproductive Medicine, and recently served as Associate Director for Professionalism and Peer Support.
An author of over 170 peer-reviewed articles and chapters, Dr. Tsen conducts clinical and basic science investigations focused on the impact of anesthesia on maternal and fetal outcomes; he currently serves as Chair for the Mass General Brigham Human Research Committee/Institutional Review Board and has been the recipient of a number of research, teaching, and mentoring awards. A former President for the Society for Obstetric Anesthesia and Perinatology and Editor-in-Chief for the International Journal of Obstetric Anesthesia, Dr. Tsen serves as an editor for the textbook Chestnut’s Obstetric Anesthesia: Principles and Practices and as a member of a number of national and international Research Grant Review Boards.
Approach to Care
I am devoted to providing the best anesthetic and health care possible, infused with professionalism, evidence based practices, global wisdom, and research insights.
Publications
Failed epidural analgesia in a childhood cancer survivor who received intrathecal chemotherapy: a case report. View Abstract
Anesthesia for reproductive healthcare from start to finish: a narrative review. View Abstract
Neuraxial initiation techniques for labor analgesia: Comparative insights on standard epidural, combined spinal-epidural and dural puncture epidural analgesia. View Abstract
Upper back, neck, and shoulder pain during labor epidural analgesia: a quality improvement initiative. View Abstract
Sacral sensory blockade from 27-gauge pencil-point dural puncture epidural analgesia or epidural analgesia in laboring nulliparous parturients: a randomized controlled trial. View Abstract
Anaesthesia for assisted reproductive technologies. View Abstract
Maternal-Fetal Conflicts in Anesthesia Practice. View Abstract
Uterine inversion. View Abstract
Labor Analgesia Initiation With Dural Puncture Epidural Versus Conventional Epidural Techniques: A Randomized Biased-Coin Sequential Allocation Trial to Determine the Effective Dose for 90% of Patients of Bupivacaine. View Abstract
Neuraxial labor analgesia: Initiation techniques. View Abstract
Obstetric comorbidity index and the odds of general vs. neuraxial anesthesia in women undergoing cesarean delivery: a retrospective cohort study. View Abstract
The venous system during pregnancy. Part 2: clinical implications. View Abstract
The venous system during pregnancy. Part 1: physiologic considerations. View Abstract
Career satisfaction in obstetric anesthesia. View Abstract
Labor prior to cesarean delivery associated with higher post-discharge opioid consumption. View Abstract
The Effect of the No Pain Labor & Delivery-Global Health Initiative on Cesarean Delivery and Neonatal Outcomes in China: An Interrupted Time-Series Analysis. View Abstract
Intrathecal catheter use after accidental dural puncture in obstetric patients: literature review and clinical management recommendations. View Abstract
A cluster quasi-randomized controlled trial of an interactive, monthly obstetric anesthesiology curriculum: impact on resident satisfaction and knowledge retention. View Abstract
Wearing an N95 Respiratory Mask. View Abstract
Wearing an N95 Respiratory Mask: An Unintended Exercise Benefit? View Abstract
The Most Influential Publications in Obstetric Anesthesiology, 1998-2017: Utilizing the Delphi Method for Expert Consensus. View Abstract
Risk Factors, Etiologies, and Screening Tools for Sepsis in Pregnant Women: A Multicenter Case-Control Study. View Abstract
Average and time-specific maternal prenatal inflammatory biomarkers and the risk of labor epidural associated fever. View Abstract
Identifying Barriers to Implementation of the National Partnership for Maternal Safety Obstetric Hemorrhage Bundle at a Tertiary Center: Utilization of the Delphi Method. View Abstract
Use of a novel non-invasive respiratory monitor to study changes in pulmonary ventilation during labor epidural analgesia. View Abstract
The effect of patient-selected or preselected music on anxiety during cesarean delivery: a randomized controlled trial. View Abstract
Too cold, too hot or just right? Temperature regulation during caesarean section. View Abstract
Effect of class III and class IV obesity on oocyte retrieval complications and outcomes. View Abstract
Update on Modalities and Techniques for Labor Epidural Analgesia and Anesthesia. View Abstract
Risk Factors, Etiologies, and Screening Tools for Sepsis in Pregnant Women: A Multicenter Case-Control Study. View Abstract
Predictors of Achieving Recommended Daily Physical Activity Among Anesthesiologists at a Large Tertiary Care Academic Center. View Abstract
In Response. View Abstract
Labor therapeutics and BMI as risk factors for postpartum preeclampsia: A case-control study. View Abstract
Patterns of Opioid Prescription and Use After Cesarean Delivery. View Abstract
The PETRA (Perinatal Emergency Team Response Assessment) Scale: A High-Fidelity Simulation Validation Study. View Abstract
A prospective study of post-cesarean delivery hypoxia after spinal anesthesia with intrathecal morphine 150µg. View Abstract
Cross-Disciplinary Perceptions of Structured Interprofessional Rounds in Promoting Teamwork Within an Academic Tertiary Care Obstetric Unit. View Abstract
A Randomized Controlled Trial of Music Use During Epidural Catheter Placement on Laboring Parturient Anxiety, Pain, and Satisfaction. View Abstract
Dural Puncture Epidural Technique Improves Labor Analgesia Quality With Fewer Side Effects Compared With Epidural and Combined Spinal Epidural Techniques: A Randomized Clinical Trial. View Abstract
Maternal outcomes of term breech presentation delivery: impact of successful external cephalic version in a nationwide sample of delivery admissions in the United States. View Abstract
Cytokines in the perinatal period - Part II. View Abstract
Cytokines in the perinatal period - Part I. View Abstract
Effect of neuraxial technique after inadvertent dural puncture on obstetric outcomes and anesthetic complications. View Abstract
A Randomized, Double-blinded Trial of a "Rule of Threes" Algorithm versus Continuous Infusion of Oxytocin during Elective Cesarean Delivery. View Abstract
The Influence of a Night-Float Call System on the Incidence of Unintentional Dural Puncture: A Retrospective Impact Study. View Abstract
The effect of co-administration of intravenous calcium chloride and oxytocin on maternal hemodynamics and uterine tone following cesarean delivery: a double-blinded, randomized, placebo-controlled trial. View Abstract
Accuracy of ICD-9-CM coding to identify small for gestational age newborns. View Abstract
Chronotropic variation in the incidence of unintentional dural puncture in parturients undergoing epidural placement. View Abstract
Emergent transesophageal echocardiography in hemodynamically unstable obstetric patients. View Abstract
Differences between anticipated and perceived difficulty and insertion duration of labor epidural techniques among anesthesiologists, nurses and patients. View Abstract
Patterns of second-line uterotonic use in a large sample of hospitalizations for childbirth in the United States: 2007-2011. View Abstract
Management of labor analgesia in a patient with acute myeloid leukemia. View Abstract
The effect of bupivacaine with fentanyl temperature on initiation and maintenance of labor epidural analgesia: a randomized controlled study. View Abstract
Epidural catheter design: history, innovations, and clinical implications. View Abstract
Anesthesiologist as epidemiologist: insights from registry studies of obstetric anesthesia-related complications. View Abstract
Fetal optimization during maternal sepsis: relevance and response of the obstetric anesthesiologist. View Abstract
The Society for Obstetric Anesthesia and Perinatology consensus statement on the management of cardiac arrest in pregnancy. View Abstract
Cardiac arrest during hospitalization for delivery in the United States, 1998-2011. View Abstract
Instituting a culture of professionalism: the establishment of a center for professionalism and peer support. View Abstract
Oxytocin protocols for cesarean delivery. View Abstract
The development and historical context of the Datta short laryngoscope handle. View Abstract
Serum uric acid as a novel marker for uterine atony and post-spinal vasopressor use during cesarean delivery. View Abstract
The learning curve associated with the epidural technique using the Episure™ AutoDetect™ versus conventional glass syringe: an open-label, randomized, controlled, crossover trial of experienced anesthesiologists in obstetric patients. View Abstract
The development, implementation, and assessment of an innovative faculty mentoring leadership program. View Abstract
Risk factors for failed conversion of labor epidural analgesia to cesarean delivery anesthesia: a systematic review and meta-analysis of observational trials. View Abstract
Practice policies for older anesthesiologists in academic departments: a national survey of academic departmental chairpersons. View Abstract
The all-seeing eye? Ultrasound technologies for neuraxial techniques. View Abstract
Association of epidural-related fever and noninfectious inflammation in term labor. View Abstract
Topical vasoconstrictor use for nasal intubation during pregnancy complicated by cardiomyopathy and preeclampsia. View Abstract
General anesthesia for cesarean delivery at a tertiary care hospital from 2000 to 2005: a retrospective analysis and 10-year update. View Abstract
Oxytocin protocols during cesarean delivery: time to acknowledge the risk/benefit ratio? View Abstract
Anesthetic management of a patient with an allergy to propylene glycol and parabens. View Abstract
Preoperative electrocardiograms: patient factors predictive of abnormalities. View Abstract
Elevation of uterine basal tone and fetal heart rate abnormalities after labor analgesia: a randomized controlled trial. View Abstract
A systematic review of randomized controlled trials that evaluate strategies to avoid epidural vein cannulation during obstetric epidural catheter placement. View Abstract
Intravenous dexmedetomidine as an adjunct for labor analgesia and cesarean delivery anesthesia in a parturient with a tethered spinal cord. View Abstract
A randomized trial of dural puncture epidural technique compared with the standard epidural technique for labor analgesia. View Abstract
Anesthetic impact of body mass index in patients undergoing assisted reproductive technologies. View Abstract
The more the merrier: should anesthesiologists be present for multiple births? View Abstract
Neuraxial techniques for labor analgesia should be placed in the lateral position. View Abstract
Anesthesia for assisted reproductive technologies. View Abstract
Value of preoperative clinic visits in identifying issues with potential impact on operating room efficiency. View Abstract
Anesthesia for interventional radiology in parturients at risk of major hemorrhage at cesarean section delivery. View Abstract
Resident training in obstetric anesthesia in the United States. View Abstract
Needles used for spinal anesthesia. View Abstract
The use of central neuraxial techniques in parturients with factor V leiden mutation. View Abstract
Placental growth factor in the cerebrospinal fluid of women with preeclampsia. View Abstract
Discriminatory proteomic biomarker analysis identifies free hemoglobin in the cerebrospinal fluid of women with severe preeclampsia. View Abstract
What's new and novel in obstetric anesthesia? Contributions from the 2003 scientific literature. View Abstract
Gerard W. Ostheimer "What's New in Obstetric Anesthesia" Lecture. View Abstract
Hemodynamic effects of spinal anesthesia and simultaneous intravenous bolus of combined phenylephrine and ephedrine versus ephedrine for cesarean delivery. View Abstract
Severe thrombocytopenia, type 2B von Willebrand disease and pregnancy. View Abstract
Use of assisted reproductive technologies and anesthesia in a patient with primary pulmonary hypertension. View Abstract
Patient satisfaction with preoperative assessment in a preoperative assessment testing clinic. View Abstract
Should local anesthetic allergy testing be routinely performed during pregnancy? View Abstract
Epidural blood patch placed in the presence of an unknown cervical epidural hematoma. View Abstract
Anesthetic management of the parturient with cardiac and diabetic diseases. View Abstract
Spinal anesthesia for cesarean delivery shortly after an epidural blood patch. View Abstract
The effect of alterations in a preoperative assessment clinic on reducing the number and improving the yield of cardiology consultations. View Abstract
Herbal medicinal products during pregnancy: are they safe? View Abstract
Human immunodeficiency virus in pregnancy. View Abstract
In vitro fertilization-induced alterations in coagulation and fibrinolysis as measured by thromboelastography. View Abstract
Combined spinal-epidural versus epidural labor analgesia on progress and outcome of labor. View Abstract
Central neuraxial blockade promotes external cephalic version success after a failed attempt. View Abstract
Anesthetic considerations for a patient with compound heterozygous medium-chain Acyl-CoA dehydrogenase deficiency. View Abstract
Herbal medicine use in parturients. View Abstract
Hypotension prophylaxis for Ceasarean section. View Abstract
Neurologic complications of labor analgesia and anesthesia. View Abstract
Transcutaneous electrical nerve stimulation does not augment epidural labor analgesia. View Abstract
Sickle cell-induced peripheral neuropathy following spinal anesthesia for cesarean delivery. View Abstract
Can estrogen influence the response to noxious stimuli? View Abstract
The mask avenger? View Abstract
Intrathecal low-dose bupivacaine versus lidocaine for in vitro fertilization procedures. View Abstract
Survey of residency training in preoperative evaluation. View Abstract
Hemodynamic effects of simultaneous administration of intravenous ephedrine and spinal anesthesia for cesarean delivery. View Abstract
Alternative medicine use in presurgical patients. View Abstract
Training in obstetric general anaesthesia: a vanishing art? View Abstract
Transcutaneous electrical nerve stimulation does not augment combined spinal epidural labour analgesia. View Abstract
In vitro fertilization. Do short-term changes in estrogen levels produce increased fibrinolysis? View Abstract
Measurements of maternal protein binding of bupivacaine throughout pregnancy. View Abstract
Is combined spinal-epidural analgesia associated with more rapid cervical dilation in nulliparous patients when compared with conventional epidural analgesia? View Abstract
Clinical effects and maternal and fetal plasma concentrations of 0.5% epidural levobupivacaine versus bupivacaine for cesarean delivery. View Abstract
Panic attacks and lactated Ringer's solution: is there a relationship? View Abstract
Anesthesia for in vitro fertilization: the addition of fentanyl to 1.5% lidocaine. View Abstract
General anesthesia for cesarean section at a tertiary care hospital 1990-1995: indications and implications. View Abstract
Anesthetic management of a parturient with olivopontocerebellar degeneration. View Abstract
Estrogen-induced changes in protein binding of bupivacaine during in vitro fertilization. View Abstract
Trigger point injections for myofascial pain during epidural analgesia for labor. View Abstract
Nitrous oxide inhalation: effects on the maternal and fetal circulations at term. View Abstract
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