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Lara Wahlster, MD, PhD
Attending Physician, Hematopoietic (Stem) Cell Transplant Program
Instructor of Pediatrics, Harvard Medical School
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Lara Wahlster, MD, PhD
Attending Physician, Hematopoietic (Stem) Cell Transplant Program
Instructor of Pediatrics, Harvard Medical School
Medical Services
Languages
English
Farsi
French
German
Education
Graduate School
Heidelberg University
2013
Heidelberg
Germany
Medical School
Heidelberg University
2013
Heidelberg
Germany
Undergraduate School
Pediatrics
Heidelberg University Children's Hospital
2014
Heidelberg
Germany
Residency
Pediatrics
Boston Combined Residency Program (BCRP)
2018
Boston
MA
Fellowship
Pediatric Hematology/Oncology/Stem Cell Transplant
Dana-Farber/Boston Children's Cancer and Blood Disorders Center
2022
Boston
MA
Publications
ANKRD26-related Thrombocytopenia 2 with a Baseline Increase in Blasts: Implications for Clinical Surveillance. View Abstract
Transcription factor networks disproportionately enrich for heritability of blood cell phenotypes. View Abstract
Inherited resilience to clonal hematopoiesis by modifying stem cell RNA regulation. View Abstract
CEBPA repression by MECOM blocks differentiation to drive aggressive leukemias. View Abstract
Regulated GATA1 expression as a universal gene therapy for Diamond-Blackfan anemia. View Abstract
Transcription factor networks disproportionately enrich for heritability of blood cell phenotypes. View Abstract
A noncoding regulatory variant in IKZF1 increases acute lymphoblastic leukemia risk in Hispanic/Latino children. View Abstract
Editorial: Advances in predisposition to bone marrow failure and hematopoietic neoplasms. View Abstract
Deciphering cell states and genealogies of human haematopoiesis. View Abstract
High-content screening identifies a small molecule that restores AP-4-dependent protein trafficking in neuronal models of AP-4-associated hereditary spastic paraplegia. View Abstract
High-Content Small Molecule Screen Identifies a Novel Compound That Restores AP-4-Dependent Protein Trafficking in Neuronal Models of AP-4-Associated Hereditary Spastic Paraplegia. View Abstract
Massively parallel base editing to map variant effects in human hematopoiesis. View Abstract
A genetic disorder reveals a hematopoietic stem cell regulatory network co-opted in leukemia. View Abstract
Familial thrombocytopenia due to a complex structural variant resulting in a WAC-ANKRD26 fusion transcript. View Abstract
I SPI1 something needed for B cells. View Abstract
COVID-19 presenting with autoimmune hemolytic anemia in the setting of underlying immune dysregulation. View Abstract
A CLK3-HMGA2 Alternative Splicing Axis Impacts Human Hematopoietic Stem Cell Molecular Identity throughout Development. View Abstract
Drug discovery for Diamond-Blackfan anemia using reprogrammed hematopoietic progenitors. View Abstract
Using tuberous sclerosis complex to understand the impact of MTORC1 signaling on mitochondrial dynamics and mitophagy in neurons. View Abstract
Impaired Mitochondrial Dynamics And Mitophagy In Neuronal Models Of Tuberous Sclerosis Complex. View Abstract
Impaired Mitochondrial Dynamics and Mitophagy in Neuronal Models of Tuberous Sclerosis Complex. View Abstract
Progress towards generation of human haematopoietic stem cells. View Abstract
Reduction of TMEM97 increases NPC1 protein levels and restores cholesterol trafficking in Niemann-pick type C1 disease cells. View Abstract
Congenital disorders of autophagy: an emerging novel class of inborn errors of neuro-metabolism. View Abstract
Parkinson's disease: A disorder of axonal mitophagy? View Abstract
International electives in the final year of German medical school education--a student's perspective. View Abstract
Modeling Parkinson's disease in a dish--a story of yeast and men. View Abstract
Molecular chaperones and protein folding as therapeutic targets in Parkinson's disease and other synucleinopathies. View Abstract
Emerging role of autophagy in pediatric neurodegenerative and neurometabolic diseases. View Abstract
Restoring impaired protein metabolism in Parkinson's disease--TFEB-mediated autophagy as a novel therapeutic target. View Abstract
Proteotoxicity and cardiac dysfunction. View Abstract
Presenilin-1 adopts pathogenic conformation in normal aging and in sporadic Alzheimer's disease. View Abstract
Familial Mediterranean fever in Germany: clinical presentation and amyloidosis risk. View Abstract
Protein degradation pathways in Parkinson's disease: curse or blessing. View Abstract
Molecular chaperones in Parkinson's disease--present and future. View Abstract
Clinical manifestations and longterm followup of a patient with CINCA/NOMID syndrome. View Abstract