Konstantinos Papadakis, MD
Pediatric Surgeon, Department of Surgery
Assistant Professor, Harvard Medical School
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Konstantinos Papadakis, MD
Pediatric Surgeon, Department of Surgery
Assistant Professor, Harvard Medical School
Medical Services
Education
Undergraduate School
University of California at Berkley
1987
Berkley
CA
Medical School
University of Vermont
1992
Burlington
VT
Residency
Rhode Island Hospital, Brown University
Providence
RI
Fellowship
Tufts New England Floating Hospital for Children
Boston
MA
Fellowship
Boston Children's Hospital
Boston
MA
Publications
Optimizing Efficacy of Vacuum Bell Therapy for Pectus Excavatum: Compliance is Key. View Abstract
Ustekinumab-Induced Vasculitis in a Patient With Crohn's Disease. View Abstract
The CNS microenvironment promotes leukemia cell survival by disrupting tumor suppression and cell cycle regulation in pediatric T-cell acute lymphoblastic leukemia. View Abstract
Latiglutenase Protects the Mucosa and Attenuates Symptom Severity in Patients With Celiac Disease Exposed to a Gluten Challenge. View Abstract
Electron Signatures of Reconnection in a Global eVlasiator Simulation. View Abstract
Quasi-Parallel Shock Reformation Seen by Magnetospheric Multiscale and Ion-Kinetic Simulations. View Abstract
Vulvar Crohn's Disease: Clinical Features and Outcomes. View Abstract
Certolizumab Trough Levels and Antibodies in Crohn Disease: A Single-Center Experience. View Abstract
A 1-Year Cross-sectional Inflammatory Bowel Disease Surveillance Colonoscopy Cohort Comparing High-definition White Light Endoscopy and Chromoendoscopy. View Abstract
Parasitic omental endometrioma: an unexpected iatrogenic sequalae of morcellation in disseminating de novo benign peritoneal disease. View Abstract
Perineal integrity can be guarded by polishing our intrapartum skills. View Abstract
Combination Biologic Therapy in Inflammatory Bowel Disease: Experience From a Tertiary Care Center. View Abstract
Intravenous Bevacizumab Reduces Transfusion Requirements and Endoscopic Interventions in Patients With Gastric Antral Vascular Ectasia and Small Bowel Angioectasia. View Abstract
The Combination of Patient-Reported Clinical Symptoms and an Endoscopic Score Correlates Well with Health-Related Quality of Life in Patients with Ulcerative Colitis. View Abstract
Evaluating the value of intrapartum fetal scalp blood sampling to predict adverse neonatal outcomes: A UK multicentre observational study. View Abstract
Vedolizumab Drug Level Correlation With Clinical Remission, Biomarker Normalization, and Mucosal Healing in Inflammatory Bowel Disease. View Abstract
Narrow band imaging evaluation of duodenal villi in patients with and without celiac disease: A prospective study. View Abstract
Mechanisms of Disease: Inflammatory Bowel Diseases. View Abstract
Outcomes of Treatment for Latent Tuberculosis Infection in Patients With Inflammatory Bowel Disease Receiving Biologic Therapy. View Abstract
Phenotype and Clinical Course of Inflammatory Bowel Disease With Co-existent Celiac Disease. View Abstract
Clinical Benefit of Capsule Endoscopy in Crohn's Disease: Impact on Patient Management and Prevalence of Proximal Small Bowel Involvement. View Abstract
Concurrent Sweet's syndrome and myopericarditis following mesalamine therapy. View Abstract
Targeting Specific Immunologic Pathways in Crohn's Disease. View Abstract
Inflammatory Bowel Disease: Updates on Molecular Targets for Biologics. View Abstract
Aberrant function of myeloid-derived suppressor cells (MDSCs) in experimental colitis and in inflammatory bowel disease (IBD) immune responses. View Abstract
P616 Natural history and phenotype of inflammatory bowel disease with co-existent celiac disease. View Abstract
The Role of the Histone Methyltransferase Enhancer of Zeste Homolog 2 (EZH2) in the Pathobiological Mechanisms Underlying Inflammatory Bowel Disease (IBD). View Abstract
O-015 YI Alterations in the FOXP3-EZH2 Pathway Associates with Increased Susceptibility to Colitis in Both Mice and Human. View Abstract
A case report of sevelamer-associated recto-sigmoid ulcers. View Abstract
Krüppel-like factor KLF10 deficiency predisposes to colitis through colonic macrophage dysregulation. View Abstract
Apolipoprotein A-I inhibits experimental colitis and colitis-propelled carcinogenesis. View Abstract
Ipilimumab-induced colitis in patients with metastatic melanoma. View Abstract
New-onset paresthesias in inflammatory bowel disease. View Abstract
An uncommon cause of abdominal pain and fever in a patient with Crohn's disease. View Abstract
A novel role for KLF14 in T regulatory cell differentiation. View Abstract
Predictors of health-related quality of life and adherence in Crohn's disease and ulcerative colitis: implications for clinical management. View Abstract
Krüppel-like factor KLF10 regulates transforming growth factor receptor II expression and TGF-ß signaling in CD8+ T lymphocytes. View Abstract
Pharmacogenetics of inflammatory bowel disease. View Abstract
Immunology of inflammatory bowel disease and molecular targets for biologics. View Abstract
Lymphocyte homing antagonists in the treatment of inflammatory bowel diseases. View Abstract
Prolonged idiopathic gastric dilatation following revascularization for chronic mesenteric ischemia. View Abstract
Cytomegalovirus infection of the ileoanal pouch: clinical characteristics and outcomes. View Abstract
Chronic diarrhea after autologous stem cell transplantation for peripheral T-cell lymphoma. View Abstract
Hepcidin is a key mediator of anemia of inflammation in Crohn's disease. View Abstract
Treatment of experimental murine colitis with CD40 antisense oligonucleotides delivered in amphoteric liposomes. View Abstract
Colorectal cancer screening and surveillance in Crohn's colitis. View Abstract
Predicting outcomes after restorative proctocolectomy for ulcerative colitis. View Abstract
Dysplasia and cancer in inflammatory bowel disease. View Abstract
Pulmonary manifestations of inflammatory bowel disease: case presentations and review. View Abstract
Combination of innate and adaptive immune alterations increased the likelihood of fibrostenosis in Crohn's disease. View Abstract
A case of orbital myositis preceding the intestinal symptoms of Crohn's disease. View Abstract
Report of the ECCO workshop on anti-TNF therapy failures in inflammatory bowel diseases: biological roles and effects of TNF and TNF antagonists. View Abstract
CD8+ cells protect mice against reinfection with the intestinal parasite Eimeria falciformis. View Abstract
Diagnostic approach to small bowel involvement in inflammatory bowel disease: view of the endoscopist. View Abstract
Capsule endoscopy in patients with Crohn's disease: diagnostic yield and safety. View Abstract
Immunosuppression impairs response to pneumococcal polysaccharide vaccination in patients with inflammatory bowel disease. View Abstract
Genome-wide association study identifies eight loci associated with blood pressure. View Abstract
Musculoskeletal manifestations of inflammatory bowel disease. View Abstract
Crohn's disease: Adalimumab improves quality of life. View Abstract
Comparison of commercially available serologic kits for the detection of celiac disease. View Abstract
Capsule endoscopy in the evaluation and management of inflammatory bowel disease: a future perspective. View Abstract
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. View Abstract
Why are cytokines targeted for biological therapy in IBD? View Abstract
Endoscopic evaluation of patients with inflammatory bowel disease. View Abstract
Proximal small intestinal CD detected by CE. View Abstract
Visilizumab induces apoptosis of mucosal T lymphocytes in ulcerative colitis through activation of caspase 3 and 8 dependent pathways. View Abstract
Common variants near MC4R are associated with fat mass, weight and risk of obesity. View Abstract
Both preoperative perinuclear antineutrophil cytoplasmic antibody and anti-CBir1 expression in ulcerative colitis patients influence pouchitis development after ileal pouch-anal anastomosis. View Abstract
Thiopurine methyltransferase activity combined with 6-thioguanine metabolite levels predicts clinical response to thiopurines in patients with inflammatory bowel disease. View Abstract
LDL-cholesterol concentrations: a genome-wide association study. View Abstract
Minimally invasive closure of pediatric umbilical hernias. View Abstract
Family history and serology predict Crohn's disease after ileal pouch-anal anastomosis for ulcerative colitis. View Abstract
Diagnostic yield of capsule endoscopy in ulcerative colitis and inflammatory bowel disease of unclassified type (IBDU). View Abstract
Does infliximab influence surgical morbidity of ileal pouch-anal anastomosis in patients with ulcerative colitis? View Abstract
Characterization of FOXP3+CD4+ regulatory T cells in Crohn's disease. View Abstract
Hepatotoxicity of 6-mercaptopurine (6-MP) and Azathioprine (AZA) in adult IBD patients. View Abstract
A prospective multivariate analysis of clinical factors associated with pouchitis after ileal pouch-anal anastomosis. View Abstract
Predicting a change in diagnosis from ulcerative colitis to Crohn's disease: a nested, case-control study. View Abstract
Esophageal Crohn's disease treated successfully with adalimumab. View Abstract
Anti-flagellin (CBir1) phenotypic and genetic Crohn's disease associations. View Abstract
Phenotype and effector function of CC chemokine receptor 9-expressing lymphocytes in small intestinal Crohn's disease. View Abstract
Expression and functional characterization of FOXP3+ CD4+ regulatory T cells in ulcerative colitis. View Abstract
Antibodies to I2 predict clinical response to fecal diversion in Crohn's disease. View Abstract
NOD2 variants and antibody response to microbial antigens in Crohn's disease patients and their unaffected relatives. View Abstract
Patients with inflammatory bowel disease are at risk for vaccine-preventable illnesses. View Abstract
Familial expression of anti-Escherichia coli outer membrane porin C in relatives of patients with Crohn's disease. View Abstract
Adalimumab for the treatment of Crohn's disease. View Abstract
Wireless capsule endoscopy in the evaluation of patients with suspected or known Crohn's disease. View Abstract
Elevated platelet count before ileal pouch-anal anastomosis for ulcerative colitis is associated with the development of chronic pouchitis. View Abstract
Serologic responses in indeterminate colitis patients before ileal pouch-anal anastomosis may determine those at risk for continuous pouch inflammation. View Abstract
Antibodies to CBir1 flagellin define a unique response that is associated independently with complicated Crohn's disease. View Abstract
Dominant role for TL1A/DR3 pathway in IL-12 plus IL-18-induced IFN-gamma production by peripheral blood and mucosal CCR9+ T lymphocytes. View Abstract
Association of anti-tumor necrosis factor therapy with the development of multiple sclerosis. View Abstract
Safety and efficacy of adalimumab (D2E7) in Crohn's disease patients with an attenuated response to infliximab. View Abstract
Expression and regulation of the chemokine receptor CXCR3 on lymphocytes from normal and inflammatory bowel disease mucosa. View Abstract
Crohn's ileitis after liver transplantation from a living related donor with Crohn's disease. View Abstract
A pilot study of adalimumab in infliximab-allergic patients. View Abstract
The spectrum of gastrointestinal toxicity and effect on disease activity of selective cyclooxygenase-2 inhibitors in patients with inflammatory bowel disease. View Abstract
TL1A synergizes with IL-12 and IL-18 to enhance IFN-gamma production in human T cells and NK cells. View Abstract
High incidence of anergy in inflammatory bowel disease patients limits the usefulness of PPD screening before infliximab therapy. View Abstract
Association of antibody responses to microbial antigens and complications of small bowel Crohn's disease. View Abstract
Initial experience with wireless capsule enteroscopy in the diagnosis and management of inflammatory bowel disease. View Abstract
Chemokines in inflammatory bowel disease. View Abstract
Infliximab in the treatment of medically refractory indeterminate colitis. View Abstract
CC chemokine receptor 9 expression defines a subset of peripheral blood lymphocytes with mucosal T cell phenotype and Th1 or T-regulatory 1 cytokine profile. View Abstract
Optimizing the therapeutic potential of azathioprine/6-mercaptopurine in the treatment of inflammatory bowel disease. View Abstract
Anti-CD2O chimeric monoclonal antibody (rituximab) treatment of immune-mediated thrombocytopenia associated with Crohn's disease. View Abstract
Mutations in NOD2 are associated with fibrostenosing disease in patients with Crohn's disease. View Abstract
Diagnosis and misdiagnosis of inflammatory bowel disease. View Abstract
CCR9-positive lymphocytes and thymus-expressed chemokine distinguish small bowel from colonic Crohn's disease. View Abstract
Outcome of cytomegalovirus infections in patients with inflammatory bowel disease. View Abstract
The role of thymus-expressed chemokine and its receptor CCR9 on lymphocytes in the regional specialization of the mucosal immune system. View Abstract
The role of chemokines and chemokine receptors in mucosal inflammation. View Abstract
Tumor necrosis factor: biology and therapeutic inhibitors. View Abstract
Late-gestation tracheal occlusion in the fetal lamb causes rapid lung growth with type II cell preservation. View Abstract
Role of cytokines in the pathogenesis of inflammatory bowel disease. View Abstract
Serologic testing in inflammatory bowel disease: its value in indeterminate colitis. View Abstract
An open-label pilot study of low-dose thalidomide in chronically active, steroid-dependent Crohn's disease. View Abstract
Recurrent bleeding from a duodenal plasmacytoma treated successfully with embolization of the gastroduodenal artery. View Abstract
Current theories on the causes of inflammatory bowel disease. View Abstract
The role of apoptosis in normal and accelerated lung development in fetal rabbits. View Abstract
The changing presentation of pyloric stenosis. View Abstract
Predictive value of monitoring parameters in fetal surgery. View Abstract
Temporary tracheal occlusion causes catch-up lung maturation in a fetal model of diaphragmatic hernia. View Abstract
Single-port tracheoscopic surgery in the fetal lamb. View Abstract
Stenotrophomonas maltophilia meningitis. Report of two cases and review of the literature. View Abstract
Fetal lung growth after tracheal ligation is not solely a pressure phenomenon. View Abstract
Patterns of pulmonary metastasis from uterine cancer. View Abstract
Natural history of patients with pulmonary metastases from uterine cancer. View Abstract
Fluconazole versus amphotericin B in the treatment of hematogenous candidiasis: a matched cohort study. View Abstract
Bacteremia due to Stenotrophomonas (Xanthomonas) maltophilia: a prospective, multicenter study of 91 episodes. View Abstract
Stenotrophomonas (Xanthomonas) maltophilia urinary tract infection. A disease that is usually severe and complicated. View Abstract
Septic prepatellar bursitis caused by Stenotrophomonas (Xanthomonas) maltophilia. View Abstract
Stenotrophomonas maltophilia: an unusual cause of biliary sepsis. View Abstract
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