Kevin Liu, MD, DPhil

Attending Physician, Cancer and Blood Disorders Center; Director of Sarcoma Radiation Oncology, Massachusetts General Hospital
Assistant Professor of Radiation Oncology, Harvard Medical School
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Kevin Liu, MD, DPhil

Kevin Liu, MD, DPhil

Attending Physician, Cancer and Blood Disorders Center; Director of Sarcoma Radiation Oncology, Massachusetts General Hospital
Assistant Professor of Radiation Oncology, Harvard Medical School
Education
Undergraduate School
Harvard College
2011
Cambridge
MA
Graduate School
University of Oxford
2014
Oxford
United Kington
Medical School
Harvard Medical School
2018
Boston
MA
Internship
Internal Medicine
University of California, San Diego
2019
San Diego
CA
Residency
Radiation Oncology
Harvard Radiation Oncology Program
2023
Boston
MA
Certifications
American Board of Radiology (Radiation Oncology)
Professional History

Dr. Liu is an Assistant Professor of Radiation Oncology at Harvard Medical School and the Director of Sarcoma Radiation Oncology at Massachusetts General Hospital. He has a clinical focus on sarcomas and pediatric malignancies. He received his undergraduate degree summa cum laude from Harvard College, his doctorate from the University of Oxford as a Fulbright and Clarendon Scholar, and his medical degree from Harvard Medical School. Dr. Liu completed his residency in radiation oncology at the Harvard Radiation Oncology Program where he served as Chief Resident.

His research focuses on novel treatment strategies for sarcomas, diffuse midline gliomas, high-grade gliomas, and neuroblastomas; improving outcomes after radiation for patients with sarcomas and pediatric patients with cancer; developing treatment paradigms for rare diseases; and closing gaps in healthcare disparities for underrepresented patient populations. His research has been published in The Lancet Oncology, Journal of Clinical Oncology, JAMA Oncology, International Journal of Radiation Oncology • Biology • Physics, and Cancer, and Radiotherapy & Oncology. He also serves as an associate editor for Frontiers in Oncology. Dr. Liu teaches and mentors medical students and residents.

Publications

Longitudinal Risk Prediction for Pediatric Glioma with Temporal Deep Learning. View Abstract
Role of adjuvant radiotherapy modality on clinical outcomes for early-stage uterine carcinosarcoma. View Abstract
Treatment Approach for Metastatic Intracranial Germinoma: A Multi-Institutional Experience. View Abstract
The association between postoperative photon radiotherapy dose and disease control and salvage treatment in pediatric and adolescent ependymoma: a multi-institutional investigation. View Abstract
Hypofractionated Palliative Radiotherapy for Relapsed and Refractory High-Risk Neuroblastoma. View Abstract
Multimodal deep learning improves recurrence risk prediction in pediatric low-grade gliomas. View Abstract
A foundation model for generalized brain MRI analysis. View Abstract
Changes in Merkel cell oncoprotein antibodies after radiation therapy in curatively treated Merkel cell carcinoma and association with recurrence. View Abstract
Stepwise Transfer Learning for Expert-level Pediatric Brain Tumor MRI Segmentation in a Limited Data Scenario. View Abstract
Longitudinal risk prediction for pediatric glioma with temporal deep learning. View Abstract
Patterns of recurrence after radiotherapy for high-risk neuroblastoma: Implications for radiation dose and field. View Abstract
Case Report: Low-grade glioma with NF1 loss of function mimicking diffuse intrinsic pontine glioma. View Abstract
Noninvasive Molecular Subtyping of Pediatric Low-Grade Glioma with Self-Supervised Transfer Learning. View Abstract
Noninvasive molecular subtyping of pediatric low-grade glioma with self-supervised transfer learning. View Abstract
Everolimus for Children With Recurrent or Progressive Low-Grade Glioma: Results From the Phase II PNOC001 Trial. View Abstract
Automated temporalis muscle quantification and growth charts for children through adulthood. View Abstract
Genetic architecture of the acute and persistent immune cell response after radiation exposure. View Abstract
Expert-level pediatric brain tumor segmentation in a limited data scenario with stepwise transfer learning. View Abstract
Radiotherapy for Primary Pediatric Central Nervous System Malignancies: Current Treatment Paradigms and Future Directions. View Abstract
Clinical outcomes of radiation therapy for transgender and gender-expansive people with cancer. View Abstract
Evaluation of prevalence and outcomes of serial tyrosine kinase inhibitor use in pediatric patients with advanced solid tumors. View Abstract
Multi-institutional Characterization of Outcomes for Pediatric and Young Adult Patients With High-Risk Myxopapillary Ependymoma After Radiation Therapy. View Abstract
Targeting macrophage Syk enhances responses to immune checkpoint blockade and radiotherapy in high-risk neuroblastoma. View Abstract
Gender-Affirming Surgery and Cancer: Considerations for Radiation Oncologists for Pelvic Radiation in Transfeminine Patients. View Abstract
Pediatric low-grade glioma: Targeted therapeutics and clinical trials in the molecular era. View Abstract
Low-dose proton radiotherapy for pediatric choroidal hemangioma: A case series. View Abstract
A druggable addiction to de novo pyrimidine biosynthesis in diffuse midline glioma. View Abstract
Clinical outcomes and considerations of gender-affirming care for transgender and gender-diverse pediatric and young adult patients with cancer. View Abstract
Multi-institutional analysis of central nervous system germ cell tumors in patients with Down syndrome. View Abstract
Comparison of Pulmonary Toxicity after Total Body Irradiation- and Busulfan-Based Myeloablative Conditioning for Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Patients. View Abstract
Characterization of clinical outcomes after shorter course hypofractionated and standard-course radiotherapy for stage I-III curatively-treated Merkel cell carcinoma. View Abstract
DICER1 mutations in primary central nervous system tumors: new insights into histologies, mutations, and prognosis. View Abstract
"Per protocol" practice patterns for Children's Oncology Group trials within the radiation oncology community. View Abstract
Surgical complications and clinical outcomes after dose-escalated trimodality therapy for non-small cell lung cancer in the era of intensity-modulated radiotherapy. View Abstract
Prospective Longitudinal Assessment of Health-related Quality of Life in Patients With Brain Metastases Undergoing Radiation Therapy. View Abstract
Clinical outcomes for pediatric patients receiving radiotherapy for solid tumor central nervous system metastases. View Abstract
Harnessing Lactate Metabolism for Radiosensitization. View Abstract
Longitudinal multicentre retrospective cohort study of treatment outcomes in extramammary Paget disease. View Abstract
Long-term outcomes of pediatric and young adult patients receiving radiotherapy for nonmalignant vascular anomalies. View Abstract
Clinical outcomes of pediatric patients with autism spectrum disorder and other neurodevelopmental disorders and intracranial germ cell tumors. View Abstract
Development and Implementation of an Online Adaptive Stereotactic Body Radiation Therapy Workflow for Treatment of Intracardiac Metastasis. View Abstract
Clinical Characteristics, Experiences, and Outcomes of Transgender Patients With Cancer. View Abstract
A Multi-institutional Comparative Analysis of Proton and Photon Therapy-Induced Hematologic Toxicity in Patients With Medulloblastoma. View Abstract
Reirradiation practices for children with diffuse intrinsic pontine glioma. View Abstract
Phase I/II Study of Stereotactic Body Radiation Therapy for Pulmonary Metastases in Pediatric Patients. View Abstract
Improving Diversity and Inclusion in the Post-Coronavirus Disease 2019 Era Through a Radiation Oncology Intensive Shadowing Experience (RISE). View Abstract
"Re-educating" Tumor Associated Macrophages as a Novel Immunotherapy Strategy for Neuroblastoma. View Abstract
The use of interval-compressed chemotherapy with the addition of vincristine, irinotecan, and temozolomide for pediatric patients with newly diagnosed desmoplastic small round cell tumor. View Abstract
Prospective Evaluation of Radiation Dose Escalation in Patients With High-Risk Neuroblastoma and Gross Residual Disease After Surgery: A Report From the Children's Oncology Group ANBL0532 Study. View Abstract
Characterizing diversity in the tumor-immune microenvironment of distinct subclasses of gastroesophageal adenocarcinomas. View Abstract
Macrophage Syk-PI3K? Inhibits Antitumor Immunity: SRX3207, a Novel Dual Syk-PI3K Inhibitory Chemotype Relieves Tumor Immunosuppression. View Abstract
Brainstem Injury in Pediatric Patients Receiving Posterior Fossa Photon Radiation. View Abstract
SF2523: Dual PI3K/BRD4 Inhibitor Blocks Tumor Immunosuppression and Promotes Adaptive Immune Responses in Cancer. View Abstract
Towards a standard of care in oncology for transgender patients. View Abstract
Risk stratification by somatic mutation burden in Ewing sarcoma. View Abstract
Eliminating Daily Shifts, Tattoos, and Skin Marks: Streamlining Isocenter Localization With Treatment Plan Embedded Couch Values for External Beam Radiation Therapy. View Abstract
Reduced-Intensity Conditioning Regimens, Prior Chronic Lymphocytic Leukemia, and Graft-Versus-Host Disease Are Associated with Higher Rates of Skin Cancer after Allogeneic Hematopoietic Stem Cell Transplantation. View Abstract
Characterization of long-term outcomes for pediatric patients with epithelioid hemangioma. View Abstract
De novo ATP1A3 and compound heterozygous NLRP3 mutations in a child with autism spectrum disorder, episodic fatigue and somnolence, and muckle-wells syndrome. View Abstract
Dual HDAC and PI3K Inhibition Abrogates NF?B- and FOXM1-Mediated DNA Damage Response to Radiosensitize Pediatric High-Grade Gliomas. View Abstract
A cross-sectional survey of long-term outcomes for patients with diffuse capillary malformation with overgrowth. View Abstract
Contact Dermatitis Associated with Alopecia and Hyperpigmentation. View Abstract
A Practical Approach to the Diagnosis and Management of Hair Loss in Children and Adolescents. View Abstract
A Cautionary Tale: Risks of Radiation Therapy De-Escalation in Pediatric Malignancies. View Abstract
Painful Ulcerative Lesions on Bilateral Lower Extremities. View Abstract
A novel de novo mutation in ATP1A3 and childhood-onset schizophrenia. View Abstract
Body habitus, serum albumin, and the outcomes after craniotomy for tumor: a National Surgical Quality Improvement Program analysis. View Abstract
Ctip1 Regulates the Balance between Specification of Distinct Projection Neuron Subtypes in Deep Cortical Layers. View Abstract
Thrombocytopenia and craniotomy for tumor: A National Surgical Quality Improvement Program analysis. View Abstract
The Evolutionarily Conserved Tre2/Bub2/Cdc16 (TBC), Lysin Motif (LysM), Domain Catalytic (TLDc) Domain Is Neuroprotective against Oxidative Stress. View Abstract
Length of hospital stay after craniotomy for tumor: a National Surgical Quality Improvement Program analysis. View Abstract
Epithelial PD-L2 Expression Marks Barrett's Esophagus and Esophageal Adenocarcinoma. View Abstract
Oxr1 improves pathogenic cellular features of ALS-associated FUS and TDP-43 mutations. View Abstract
Neuron-specific antioxidant OXR1 extends survival of a mouse model of amyotrophic lateral sclerosis. View Abstract