John Zupancic, MD, MS, ScD
Physician in Medicine, Division of Newborn Medicine
Assistant Professor of Pediatrics, Harvard Medical School
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John Zupancic, MD, MS, ScD
Physician in Medicine, Division of Newborn Medicine
Assistant Professor of Pediatrics, Harvard Medical School
Medical Services
Languages
English
Education
Undergraduate School
Victoria College, University of Toronto
1988
Toronto, Ontario
Canada
Medical School
McMaster University
1991
Toronto, Ontario
Canada
Internship
Pediatrics
McMaster University
1991
Toronto, Ontario
Canada
Residency
Pediatrics
McMaster University
1995
Toronto, Ontario
Canada
Fellowship
Harvard Neonatal-Perinatal Medicine Training Program
1995
Boston
MA
Graduate School
ScD, Health Policy
Harvard School of Public Health
2001
Boston
MA
Certifications
American Board of Pediatrics (General)
American Board of Pediatrics (Neonatal-Perinatal Medicine)
Approach to Care
In the Boston Children’s Hospital (BCH) Neonatal Intensive Care Unit (NICU) our philosophy is to ensure that every patient receives the best care for the best possible outcomes. We consider our “patient” to be the baby and the family; we are constantly striving to serve the needs of both. This requires a team based approach with all members being essential.
Publications
Clinical Characteristics of Necrotizing Enterocolitis Diagnosed by Independent Adjudication of Abdominal Radiographs, Laparotomy, or Autopsy in Preterm Infants in the "Connection Trial". View Abstract
Measuring practice preference variation for quality improvement in neonatal respiratory care. View Abstract
Community Considerations for Aggressive Intensive Care Therapy for Infants <24+0 Weeks of Gestation. View Abstract
Measuring practice preference variation for quality improvement: development of the Neonatology Survey of Interdisciplinary Groups in Healthcare Tool (NSIGHT). View Abstract
Asperger's syndrome - about time to rename it? View Abstract
Systemic corticosteroids for the prevention of bronchopulmonary dysplasia, a network meta-analysis. View Abstract
Prediction and Prevention of Preterm Birth: Secondary Analysis of a Randomized Intervention Trial. View Abstract
Economic considerations for resuscitative interventions in the immediate newborn period. View Abstract
Machine learning: remember the fundamentals. View Abstract
Change in neurodevelopmental outcomes for extremely premature infants over time: a systematic review and meta-analysis. View Abstract
Using the Neonatal Intensive Care Unit Wisely: A National Survey of Clinicians Regarding Practices for Lower-Acuity Care. View Abstract
The Trend in Costs of Tertiary-Level Neonatal Intensive Care for Neonates Born Preterm at 220/7-286/7 Weeks of Gestation from 2010 to 2019 in Canada. View Abstract
A Blueprint for Advocacy in Neonatology. View Abstract
Study protocol for reducing disparity in receipt of mother's own milk in very low birth weight infants (ReDiMOM): a randomized trial to improve adherence to sustained maternal breast pump use. View Abstract
Clinical and economic evaluation of a proteomic biomarker preterm birth risk predictor: cost-effectiveness modeling of prenatal interventions applied to predicted higher-risk pregnancies within a large and diverse cohort. View Abstract
Economic considerations at the threshold of viability. View Abstract
Physician wellbeing during the COVID-19 pandemic: an acute on chronic condition. View Abstract
Cost-Effectiveness of a Proteomic Test for Preterm Birth Prediction. View Abstract
Quantifying the variation in neonatal transport referral patterns using network analysis. View Abstract
COVID-19 preparedness-a survey among neonatal care providers in low- and middle-income countries. View Abstract
Broadening the scope and scale of quality improvement in neonatology. View Abstract
The financial burden on families of infants requiring neonatal intensive care. View Abstract
Unbiasing costs? An appraisal of economic assessment alongside randomized trials in neonatology. View Abstract
Introduction: Harnessing economic assessment to improve outcomes in neonatology. View Abstract
Higher or Lower Hemoglobin Transfusion Thresholds for Preterm Infants. View Abstract
A Graded Approach to Intravenous Dextrose for Neonatal Hypoglycemia Decreases Blood Glucose Variability, Time in the Neonatal Intensive Care Unit, and Cost of Stay. View Abstract
Cost-effectiveness and pricing of caffeine. View Abstract
Neonates in the COVID-19 pandemic. View Abstract
Quantifying the Where and How Long of Newborn Care. View Abstract
International comparison of guidelines for managing neonates at the early phase of the SARS-CoV-2 pandemic. View Abstract
Using Neonatal Intensive Care Units More Wisely for At-Risk Newborns and Their Families. View Abstract
A trial comparing continuous positive airway pressure (CPAP) devices in preterm infants. View Abstract
Caring for Newborns Born to Mothers With COVID-19: More Questions Than Answers. View Abstract
Ten-year trends in infant neuroimaging from US Neonatal Intensive Care Units. View Abstract
Telephone-based nurse-delivered interpersonal psychotherapy for postpartum depression: nationwide randomised controlled trial. View Abstract
Evaluation of the economic impact of modified screening criteria for retinopathy of prematurity from the Postnatal Growth and ROP (G-ROP) study. View Abstract
Estimates of healthcare spending for preterm and low-birthweight infants in a commercially insured population: 2008-2016. View Abstract
A Collaborative Multicenter QI Initiative to Improve Antibiotic Stewardship in Newborns. View Abstract
Cost-effectiveness of Antenatal Corticosteroid Therapy vs No Therapy in Women at Risk of Late Preterm Delivery: A Secondary Analysis of a Randomized Clinical Trial. View Abstract
Evaluating the efficacy of Seattle-PAP for the respiratory support of premature neonates: study protocol for a randomized controlled trial. View Abstract
Adherence of Newborn-Specific Antibiotic Stewardship Programs to CDC Recommendations. View Abstract
Factors influencing decision making in neonatology: inhaled nitric oxide in preterm infants. View Abstract
Predicting Successful Neonatal Retro-Transfer to a Lower Level of Care. View Abstract
Burdens Beyond Biology for Sick Newborn Infants and Their Families. View Abstract
The cost of necrotizing enterocolitis in premature infants. View Abstract
Cost-Effectiveness of Supplemental Donor Milk Versus Formula for Very Low Birth Weight Infants. View Abstract
Value-based care: the preference of outcome over prediction. View Abstract
Do trials reduce uncertainty? Assessing impact through cumulative meta-analysis of neonatal RCTs. View Abstract
Improving Value in Neonatal Intensive Care. View Abstract
Network analysis: a novel method for mapping neonatal acute transport patterns in California. View Abstract
Longer and deeper cooling for hypoxic ischemic encephalopathy in neonates does not reduce mortality. View Abstract
Should we believe in transfusion-associated enterocolitis? Applying a GRADE to the literature. View Abstract
Clinical and Cost Impact Analysis of a Novel Prognostic Test for Early Detection of Preterm Birth. View Abstract
Prospective economic evaluation alongside the non-invasive ventilation trial. View Abstract
Evidence, Quality, and Waste: Solving the Value Equation in Neonatology. View Abstract
"Waste not, want not", or the cost of doing the wrong thing. View Abstract
Choosing Wisely in Newborn Medicine: Five Opportunities to Increase Value. View Abstract
Resource distribution in neonatology: beyond the Pareto principle. View Abstract
A risk-adjusted, composite outcomes score and resource utilization metrics for very low-birth-weight infants. View Abstract
Effect of an enhanced medical home on serious illness and cost of care among high-risk children with chronic illness: a randomized clinical trial. View Abstract
Baby-MONITOR: a composite indicator of NICU quality. View Abstract
DoMINO: Donor milk for improved neurodevelopmental outcomes. View Abstract
Stratification of risk of early-onset sepsis in newborns = 34 weeks' gestation. View Abstract
Developing a quality and safety curriculum for fellows: lessons learned from a neonatology fellowship program. View Abstract
Nurse-to-patient ratios and neonatal outcomes: a brief systematic review. View Abstract
Prospective economic evaluation of a peer support intervention for prevention of postpartum depression among high-risk women in Ontario, Canada. View Abstract
Correlation of neonatal intensive care unit performance across multiple measures of quality of care. View Abstract
Do transfusions cause necrotizing enterocolitis? The complementary role of randomized trials and observational studies. View Abstract
Variations in definitions of mortality have little influence on neonatal intensive care unit performance ratings. View Abstract
The effect of telephone-based interpersonal psychotherapy for the treatment of postpartum depression: study protocol for a randomized controlled trial. View Abstract
Relationship between attrition and neurodevelopmental impairment rates in extremely preterm infants at 18 to 24 months: a systematic review. View Abstract
Neonatal intensive care unit discharge preparedness: primary care implications. View Abstract
The impact of maternal characteristics on the moderately premature infant: an antenatal maternal transport clinical prediction rule. View Abstract
Development and pretesting of a decision-aid to use when counseling parents facing imminent extreme premature delivery. View Abstract
Estimating the probability of neonatal early-onset infection on the basis of maternal risk factors. View Abstract
Economic evaluation alongside the Premature Infants in Need of Transfusion randomised controlled trial. View Abstract
Survival rates in extremely low birthweight infants depend on the denominator: avoiding potential for bias by specifying denominators. View Abstract
Formal selection of measures for a composite index of NICU quality of care: Baby-MONITOR. View Abstract
Health state preferences associated with weight status in children and adolescents. View Abstract
Prematurity: an overview and public health implications. View Abstract
Variation in diagnosis of apnea in moderately preterm infants predicts length of stay. View Abstract
Economic evaluation of caffeine for apnea of prematurity. View Abstract
Clinical benefits, costs, and cost-effectiveness of neonatal intensive care in Mexico. View Abstract
Patient-to-nurse ratios and outcomes of moderately preterm infants. View Abstract
Interinstitutional variation in prediction of death by SNAP-II and SNAPPE-II among extremely preterm infants. View Abstract
Economic evaluation of inhaled nitric oxide in preterm infants undergoing mechanical ventilation. View Abstract
Are families prepared for discharge from the NICU? View Abstract
Economic evaluation of recombinant human copper zinc superoxide dismutase administered at birth to premature infants. View Abstract
Are we satisfied with the way we review an article? View Abstract
Effect of peer support on prevention of postnatal depression among high risk women: multisite randomised controlled trial. View Abstract
Cost-effectiveness of early treatment for retinopathy of prematurity. View Abstract
The economics of elective cesarean section. View Abstract
Supporting bereaved parents: practical steps in providing compassionate perinatal and neonatal end-of-life care. A North American perspective. View Abstract
CoolSim: using industrial modeling techniques to examine the impact of selective head cooling in a model of perinatal regionalization. View Abstract
Implementing pay-for-performance in the neonatal intensive care unit. View Abstract
Neonatal intensive care unit census influences discharge of moderately preterm infants. View Abstract
Resuscitation and ventilation strategies for extremely preterm infants: a comparison study between two neonatal centers in Boston and Stockholm. View Abstract
Revalidation of the Score for Neonatal Acute Physiology in the Vermont Oxford Network. View Abstract
Early labor assessment and support at home versus telephone triage: a randomized controlled trial. View Abstract
Unstudied infants: outcomes of moderately premature infants in the neonatal intensive care unit. View Abstract
Retrospective economic evaluation of a controlled trial of indomethacin prophylaxis for patent ductus arteriosus in premature infants. View Abstract
Moderately premature infants at Kaiser Permanente Medical Care Program in California are discharged home earlier than their peers in Massachusetts and the United Kingdom. View Abstract
Prenatal consultation practices at the border of viability: a regional survey. View Abstract
Trends in severe bronchopulmonary dysplasia rates between 1994 and 2002. View Abstract
Richardson score predicts short-term adverse respiratory outcomes in newborns >/=34 weeks gestation. View Abstract
Rehospitalization in the first year of life among infants with bronchopulmonary dysplasia. View Abstract
Internet use and perceptions of information reliability by parents in a neonatal intensive care unit. View Abstract
Daily cost prediction model in neonatal intensive care. View Abstract
Cost-effectiveness analysis of predischarge monitoring for apnea of prematurity. View Abstract
Characterization of neonatal personnel time inputs and prediction from clinical variables--a time and motion study. View Abstract
Characterising doctor-parent communication in counselling for impending preterm delivery. View Abstract
Cost-effectiveness and choice of infant transport systems. View Abstract
Transport risk index of physiologic stability: a practical system for assessing infant transport care. View Abstract
A critical review of cost reduction in neonatal intensive care. I. The structure of costs. View Abstract
A critical review of cost reduction in neonatal intensive care. II. Strategies for reduction. View Abstract
Economics of prematurity in the era of managed care. View Abstract
Cost-effectiveness and implications of newborn screening for prolongation of QT interval for the prevention of sudden infant death syndrome. View Abstract
Characterization of the triage process in neonatal intensive care. View Abstract
Informed consent for randomised controlled trials in neonates. View Abstract
Determinants of parental authorization for involvement of newborn infants in clinical trials. View Abstract
Intussusception in a child with cytomegalovirus infection. View Abstract
Home esophageal self-dilatation in children. View Abstract
Dangerous economics: resource allocation in the NICU. View Abstract
Locations