Jocelyn Silvester, MD, PhD
Co-Director, Celiac Disease Program; Gastroenterologist, Division of Gastroenterology, Hepatology and Nutrition
Assistant Professor of Pediatrics, Harvard Medical School
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Jocelyn Silvester, MD, PhD
Co-Director, Celiac Disease Program; Gastroenterologist, Division of Gastroenterology, Hepatology and Nutrition
Assistant Professor of Pediatrics, Harvard Medical School
Medical Services
Languages
English
Education
Medical School
Dalhousie University , 2008 , Halifax , Nova Scotia, Canada
Dalhousie University
2008
Halifax, Nova Scotia
Canada
Residency
University of Manitoba
2012
Winnipeg, Manitoba
Canada
Fellowship
Boston Children's Hospital
2016
Boston
MA
Certifications
American Board of Pediatrics (General)
American Board of Pediatrics (Gastroenterology)
Professional History
Dr. Silvester completed her PhD in Biology at the University of Cambridge, Cambridge, England, prior to studying medicine at Dalhousie University in Halifax, Nova Scotia, Canada. She completed her residency at the University of Manitoba in Winnipeg, Canada and her Fellowship in Gastroenterology, Hepatology and Nutrition at Boston Children’s Hospital. Dr. Silvester continues to work as a general pediatrician in remote regions of Northern Canada as well as at Boston Children’s Hospital. Her research interests include the diagnosis and management of celiac disease.
Publications
Hereditary Alpha-Tryptasemia is Associated with Ongoing Symptoms in Individuals with Celiac Disease Despite Following a Gluten-Free Diet. View Abstract
Gastrointestinal and Extraintestinal Symptoms among Celiac Disease Patients Undergoing a Dose Specified Gluten Challenge: a Systematic Review and Meta-Analysis. View Abstract
SPECTREPlex: an automated, fast, high-resolution enabled approach for multiplexed cyclic imaging and tissue spatial analysis. View Abstract
Early Career Progression in Young Adults With Coeliac Disease-A Register-Based Retrospective Cohort Study. View Abstract
Assessing Mucosal Recovery During the First 15 Months of Adopting a Gluten-Free Diet in Children With Celiac Disease. View Abstract
Gluten-free schooling: Navigating challenges and triumphs for children with celiac disease. View Abstract
Identifying parentally perceived barriers for children with celiac disease to participate in elementary school meal programs. View Abstract
Effect of Adopting a Gluten-Free Diet on Exposure to Arsenic and Other Heavy Metals in Children With Celiac Disease: A Prospective Cohort Study. View Abstract
ViCE: An automated and quantitative program to assess intestinal tissue morphology. View Abstract
Clinical presentation and factors associated with gluten exposure in children with celiac disease. View Abstract
Finding the sweet spot: Diagnosing celiac disease in children with type 1 diabetes. View Abstract
HLA-DQ7 haplotype among individuals with suspected celiac disease. View Abstract
Celiac disease in North America: What is the current practice of pediatric gastroenterology providers? View Abstract
Adapting celiac immunity for the future: Addressing the immunization gap in children with celiac disease. View Abstract
Past, Present, and Future of Noninvasive Tests to Assess Gluten Exposure, Celiac Disease Activity, and End-Organ Damage. View Abstract
A tip-predominant distribution of villous intraepithelial lymphocytes is not specific to celiac disease in children with Marsh I lesions. View Abstract
Anti-infliximab antibodies and low infliximab levels correlate with drug discontinuation in pediatric inflammatory bowel disease. View Abstract
A Composite Morphometric Duodenal Biopsy Mucosal Scale for Celiac Disease Encompassing Both Morphology and Inflammation. View Abstract
Comparing Gastrointestinal Endoscopy Findings in Children with Autism, Developmental Delay, or Typical Development. View Abstract
Standardizing Randomized Controlled Trials in Celiac Disease: An International Multidisciplinary Appropriateness Study. View Abstract
A Clinician's Guide to Gluten Challenge. View Abstract
Letter to the Editor in Response to ACG Guidelines Update: Diagnosis and Management of Celiac Disease. View Abstract
Low Levels of Detectable Urine and Stool GIPs in Children with Celiac Disease on a Gluten-Free Diet. View Abstract
The Spectrum of Duodenal Histologic Findings in Patients With Trisomy 21: A Multicenter Study. View Abstract
Pancreatic enzyme supplementation versus placebo for improvement of gastrointestinal symptoms in non-responsive celiac disease: A cross-over randomized controlled trial. View Abstract
Editorial: Best supporting actors: shining a light on the diverse roles of immune cells in gastrointestinal disease. View Abstract
Review article: Becoming and being coeliac-special considerations for childhood, adolescence and beyond. View Abstract
Dating While Gluten-Free-Don't Kiss and Don't Tell? View Abstract
Survey-Based Study on Food Insecurity During COVID-19 for Households With Children on a Prescribed Gluten-Free Diet. View Abstract
Genotypes of Pain and Analgesia in a Randomized Trial of Irritable Bowel Syndrome. View Abstract
Genomic Effects Associated With Response to Placebo Treatment in a Randomized Trial of Irritable Bowel Syndrome. View Abstract
Prevalence of celiac disease in China: Meta-analysis and serological survey in high-risk populations. View Abstract
Editorial: No organ is an island: the role of gut-organ axes in human health and disease. View Abstract
Society for the Study of Celiac Disease position statement on gaps and opportunities in coeliac disease. View Abstract
Clinical classification and long-term outcomes of seronegative coeliac disease: a 20-year multicentre follow-up study. View Abstract
Patient Perspectives on the Long-term Management of Celiac Disease. View Abstract
Celiac Disease: Fallacies and Facts. View Abstract
Non-responsive celiac disease in children on a gluten free diet. View Abstract
Editorial: Advances in Gastrointestinal Immunology. View Abstract
Evaluating Responses to Gluten Challenge: A Randomized, Double-Blind, 2-Dose Gluten Challenge Trial. View Abstract
Safety of a GFD in Pregnant Women Without Celiac Disease: Investigating Ingrained Habits. View Abstract
The Gluten-Free Family Ripple Effect: The Tides that Bond and the Tides that Divide. View Abstract
Exposure sources, amounts and time course of gluten ingestion and excretion in patients with coeliac disease on a gluten-free diet. View Abstract
Reply. View Abstract
Enteric-Release Budesonide May Be Useful in the Management of Non-Responsive Celiac Disease. View Abstract
The Utility of IgA-Based Serologic Markers in Diagnosing Celiac Disease in Children 24 Months of Age or Younger. View Abstract
Development of the Dietitian Integrated Evaluation Tool for Gluten-free Diets (DIET-GFD). View Abstract
A Quantitative Assessment of Gluten Cross-contact in the School Environment for Children With Celiac Disease. View Abstract
Can individuals with celiac disease identify gluten-free foods correctly? View Abstract
Assessing the association between dipeptidyl peptidase-4 inhibitors use and celiac disease through drug adverse event reporting. View Abstract
Celiac Disease: Extraintestinal Manifestations and Associated Conditions. View Abstract
Most Patients With Celiac Disease on Gluten-Free Diets Consume Measurable Amounts of Gluten. View Abstract
Concordance between gene expression in peripheral whole blood and colonic tissue in children with inflammatory bowel disease. View Abstract
Preparation of Gluten-Free Foods Alongside Gluten-Containing Food May Not Always Be as Risky for Celiac Patients as Diet Guides Suggest. View Abstract
Inter- and Intra-assay Variation in the Diagnostic Performance of Assays for Anti-tissue Transglutaminase in 2 Populations. View Abstract
Can We Ignore the Utility of Deamidated Gliadin Peptide in the Diagnosis of Celiac Disease in Children? View Abstract
Prospective longitudinal study: use of faecal gluten immunogenic peptides to monitor children diagnosed with coeliac disease during transition to a gluten-free diet. View Abstract
Efficacy of Enteric-Release Oral Budesonide in Treatment of Acute Reactions to Gluten in Patients With Celiac Disease. View Abstract
Sequence of acquisition of self-management skills to follow a gluten-free diet by adults with celiac disease. View Abstract
Red Spot Lesions in the Duodenal Bulb Are a Highly Specific Endoscopic Sign of Celiac Disease: A Prospective Study. View Abstract
Serum zonulin is elevated in IBS and correlates with stool frequency in IBS-D. View Abstract
Lack of Follow-up of Pediatric Patients With Celiac Disease. View Abstract
(Outcome) Measure for (Intervention) Measures: A Guide to Choosing the Appropriate Noninvasive Clinical Outcome Measure for Intervention Studies in Celiac Disease. View Abstract
Disruption of the anaphase-promoting complex confers resistance to TTK inhibitors in triple-negative breast cancer. View Abstract
Symptoms of Functional Intestinal Disorders Are Common in Patients with Celiac Disease Following Transition to a Gluten-Free Diet. View Abstract
Tests for Serum Transglutaminase and Endomysial Antibodies Do Not Detect Most Patients With Celiac Disease and Persistent Villous Atrophy on Gluten-free Diets: a Meta-analysis. View Abstract
Value of IgA tTG in Predicting Mucosal Recovery in Children With Celiac Disease on a Gluten-Free Diet. View Abstract
Is Autoimmunity Infectious? The Effect of Gastrointestinal Viral Infections and Vaccination on Risk of Celiac Disease Autoimmunity. View Abstract
Information seeking and anxiety among colonoscopy-naïve adults: Direct-to-colonoscopy vs traditional consult-first pathways. View Abstract
Symptomatic suspected gluten exposure is common among patients with coeliac disease on a gluten-free diet. View Abstract
Is it gluten-free? Relationship between self-reported gluten-free diet adherence and knowledge of gluten content of foods. View Abstract
The Potential for Treatment of Potential Celiac Disease. View Abstract
Recent Advances in Celiac Disease from TTG to Gluten in Pee. View Abstract
Living gluten-free: adherence, knowledge, lifestyle adaptations and feelings towards a gluten-free diet. View Abstract
Five things to know about...celiac disease. View Abstract
The interaction between caveolin-1 and Rho-GTPases promotes metastasis by controlling the expression of alpha5-integrin and the activation of Src, Ras and Erk. View Abstract
Long-term management of patients with celiac disease: current practices of gastroenterologists in Canada. View Abstract
Long-term follow-up of individuals with celiac disease: an evaluation of current practice guidelines. View Abstract
On the structure of the stator of the mitochondrial ATP synthase. View Abstract
The expression, purification, crystallization and preliminary X-ray analysis of a subcomplex of the peripheral stalk of ATP synthase from bovine mitochondria. View Abstract
Solution structure of subunit F(6) from the peripheral stalk region of ATP synthase from bovine heart mitochondria. View Abstract
An inhibitor of poly (ADP-ribose) synthetase activity reduces contractile dysfunction and preserves high energy phosphate levels during reperfusion of the ischaemic rat heart. View Abstract
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