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Jeffrey Bolton, MD
Neurologist, Department of Neurology
Instructor of Neurology, Harvard Medical School
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Jeffrey Bolton, MD
Neurologist, Department of Neurology
Instructor of Neurology, Harvard Medical School
Medical Services
Languages
English
Education
Undergraduate School
Vanderbilt University
2002
Nashville
TN
Medical School
University of Louisville School of Medicine
2006
Louisville
KY
Internship
Children's Hospital of Philadelphia
2008
Philadelphia
PA
Residency
Boston Children's Hospital
2011
Boston
MA
Fellowship
Boston Children's Hospital
2012
Boston
MA
Certifications
American Board of Psychiatry and Neurology (Child and Adolescent Neurology)
American Board of Psychiatry and Neurology (Clinical Physiology)
Professional History
After completing residency in pediatric neurology at Boston Children’s hospital, I stayed on as a fellow in Epilepsy/Clinical Neurophysiology. I joined the department as a staff physician in July 2012 and see patients in clinic in our Weymouth satellite. I enjoy seeing patients with various neurologic disorders but have a special interest in patients with epilepsy. In addition to working in the clinic, I also spend time supervising the epilepsy in-patient and neurology consult services. During my training I became interested in epilepsy surgery and have been focusing my research work into looking at factors that influence the success of epilepsy surgery.
Approach to Care
Entering medical school with a background in neuroscience, I was naturally drawn to neurology. After rotating in pediatrics and enjoying my time spent with this patient population, it made sense to pursue a career in pediatric neurology. I am thankful that I can do something I love and help families while doing so.
Spending most of my early years in the south, I think I bring a more laid-back, southern attitude to our department. Despite my roots, I love living in Boston and feel it’s a great place to raise my family of three energetic little boys. When not at work, I enjoy spending time outdoors with my family, playing sports, hiking, biking or whatever other adventure we may stumble upon.
Spending most of my early years in the south, I think I bring a more laid-back, southern attitude to our department. Despite my roots, I love living in Boston and feel it’s a great place to raise my family of three energetic little boys. When not at work, I enjoy spending time outdoors with my family, playing sports, hiking, biking or whatever other adventure we may stumble upon.
Publications
Predicting Surgical Outcome in Drug-Resistant Epilepsy by Combining Interictal Biomarkers within a Machine Learning Framework. View Abstract
Disparities across the pediatric epilepsy surgery journey: Referral, recommendation, and completion from a national consortium. View Abstract
Evidence of language network reorganization and compromised cognitive functioning in pediatric patients with focal refractory epilepsy. View Abstract
Targeting interictal low-entropy zones during epilepsy surgery predicts successful outcomes in pediatric drug-resistant epilepsy. View Abstract
Benefits of routine ICU avoidance following stereo-electroencephalography. View Abstract
Machine learning on interictal intracranial EEG predicts surgical outcome in drug resistant epilepsy. View Abstract
Evaluating the effectiveness of medical therapy in infantile epileptic spasms syndrome due to surgically-remediable lesions. View Abstract
Overlap of spike and ripple propagation onset predicts surgical outcome in epilepsy. View Abstract
In Search of a Common Language: The Standardized Electrode Nomenclature for Stereoelectroencephalography Applications. View Abstract
Development of an International Standard Set of Outcomes and Measurement Methods for Routine Practice for Infants, Children, and Adolescents with Epilepsy: The International Consortium for Health Outcomes Measurement Consensus Recommendations. View Abstract
Development of an International Standard Set of Outcomes and Measurement Methods for Routine Practice for Adults with Epilepsy: The International Consortium for Health Outcomes Measurement Consensus Recommendations. View Abstract
A syndromic neurodevelopmental disorder caused by rare variants in PPFIA3. View Abstract
Pediatric Palliative Epilepsy Surgery: A Report From the Pediatric Epilepsy Research Consortium (PERC) Surgery Database. View Abstract
A syndromic neurodevelopmental disorder caused by rare variants in PPFIA3. View Abstract
Interictal EEG source connectivity to localize the epileptogenic zone in patients with drug-resistant epilepsy: A machine learning approach. View Abstract
A syndromic neurodevelopmental disorder caused by rare variants in PPFIA3. View Abstract
A multi-center comparison of surgical techniques for corpus Callosotomy in pediatric drug-resistant epilepsy. View Abstract
Deep Learning-Based Visual Complexity Analysis of Electroencephalography Time-Frequency Images: Can It Localize the Epileptogenic Zone in the Brain? View Abstract
Development of an online calculator for the prediction of seizure freedom following pediatric hemispherectomy using the Hemispherectomy Outcome Prediction Scale (HOPS). View Abstract
Epilepsy surgery in children with genetic etiologies: A prospective evaluation of current practices and outcomes. View Abstract
Added value of corpus callosotomy following vagus nerve stimulation in children with Lennox-Gastaut syndrome: A multicenter, multinational study. View Abstract
Influence of extent and age at corpus callosotomy on seizure outcomes. A single center experience. View Abstract
Spike propagation mapping reveals effective connectivity and predicts surgical outcome in epilepsy. View Abstract
Functional connectivity discriminates epileptogenic states and predicts surgical outcome in children with drug resistant epilepsy. View Abstract
Comparison of fMRI language laterality with and without sedation in pediatric epilepsy. View Abstract
Non-invasive mapping of epileptogenic networks predicts surgical outcome. View Abstract
Stereoelectroencephalography followed by combined electrode removal and MRI-guided laser interstitial thermal therapy or open resection: a single-center series in pediatric patients with medically refractory epilepsy. View Abstract
Interictal Connectivity Revealed by Granger Analysis of Stereoelectroencephalography: Association With Ictal Onset Zone, Resection, and Outcome. View Abstract
Discrepant expressive language lateralization in children and adolescents with epilepsy. View Abstract
Mendelian etiologies identified with whole exome sequencing in cerebral palsy. View Abstract
Surgical evaluation in children <3 years of age with drug-resistant epilepsy: Patient characteristics, diagnostic utilization, and potential for treatment delays. View Abstract
A Standardized Electrode Nomenclature for Stereoelectroencephalography Applications. View Abstract
Comparison of the real-world effectiveness of vertical versus lateral functional hemispherotomy techniques for pediatric drug-resistant epilepsy: A post hoc analysis of the HOPS study. View Abstract
Subclinical seizures detected on intracranial EEG: Patient characteristics and impact on surgical outcome in a single pediatric epilepsy surgery center. View Abstract
Presurgical accuracy of dipole clustering in MRI-negative pediatric patients with epilepsy: Validation against intracranial EEG and resection. View Abstract
Hemispherectomy Outcome Prediction Scale: Development and validation of a seizure freedom prediction tool. View Abstract
Patterns of anti-seizure medication (ASM) use in pediatric patients with surgically managed epilepsy: A retrospective review of data from Boston Children's Hospital. View Abstract
The Evolution of Subclinical Seizures in Children With Tuberous Sclerosis Complex. View Abstract
Non-invasive Seizure Localization with Ictal Single-Photon Emission Computed Tomography is Impacted by Preictal/Early Ictal Network Dynamics. View Abstract
Surgical resection of ripple onset predicts outcome in pediatric epilepsy. View Abstract
Seizure clustering during presurgical electroencephalographic monitoring in children. View Abstract
Pediatric epilepsy surgery. View Abstract
Safety and retention rate of rufinamide in 300 patients: a single pediatric epilepsy center experience. View Abstract
Clobazam: effect on frequency of seizures and safety profile in different subgroups of children with epilepsy. View Abstract
Juvenile myasthenia gravis: three case reports and a literature review. View Abstract
Trust and the healing encounter: an examination of an unorthodox healing performance. View Abstract
Alternatively spliced isoforms of a Cis2-His2 zinc-finger domain. Developmental regulation and binding-site selection. View Abstract
Sequence discrimination by alternatively spliced isoforms of a DNA binding zinc finger domain. View Abstract
Asymptomatic bronchogenic cysts: what is the best management? View Abstract