Jacob Bledsoe, MD
Director of Hematopathology, Department of Pathology
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Jacob Bledsoe, MD
Director of Hematopathology, Department of Pathology
Medical Services
Languages
English
Education
Undergraduate School
Northwestern University
Evanston
IL
Medical School
Drexel University College of Medicine
Philadelphia
PA
Residency
Massachusetts General Hospital
Boston
MA
Fellowship
Massachusetts General Hospital
Boston
MA
Certifications
American Board of Pathology (Anatomic Clinical Pathology)
American Board of Pathology (Hematopathology)
Publications
ANKRD26-related Thrombocytopenia 2 with a Baseline Increase in Blasts: Implications for Clinical Surveillance. View Abstract
Clinicopathologic Features and the Spectrum of Myelokathexis in Warts, Hypogammaglobulinemia, Infections, Myelokathexis Syndrome. View Abstract
Clinical Characteristics and Treatment of Histiocytic Disorders in Children. View Abstract
CYLD-mutated anal squamous cell carcinoma: An uncommon entity associated with cylindroma-like morphology and adverse clinical features. View Abstract
Chronic Stenosing Enteritis: A Variant of Chronic Non-specific Stenosing Ulceration (CNSU) that Is Distinct from Crohn's Disease. View Abstract
Erythroblastic Sarcoma in Adults and Children: Different Pathways to the Same Destination. View Abstract
Clinical, immunophenotypic, and genomic findings of acute myeloid leukemia with RAM immunophenotype: Comparison with other CD56-positive acute leukemias. View Abstract
Features of hyperinflammation link the biology of Epstein-Barr virus infection and cytokine storm syndromes. View Abstract
Hematologic Cancer after Gene Therapy for Cerebral Adrenoleukodystrophy. View Abstract
Primary CNS histiocytic sarcoma: Two case reports highlighting a novel MIGA2::BRAF gene fusion and genome-wide DNA methylation profiling results. View Abstract
Discerning clinicopathological features of congenital neutropenia syndromes: an approach to diagnostically challenging differential diagnoses. View Abstract
Induction of remission after donor lymphocyte infusion following allogeneic transplant in a case of pediatric primary myelofibrosis. View Abstract
A novel transmembrane CXCR4 variant that expands the WHIM genotype-phenotype paradigm. View Abstract
Frameshift Mutations in Leukemia-Associated Genes Correlate With Superior Outcomes in Patients Undergoing Allogeneic Stem Cell Transplant for De Novo Acute Myeloid Leukemia. View Abstract
Acute Promyelocytic Leukemia With Torque Teno Mini Virus::RARA Fusion: An Approach to Screening and Diagnosis. View Abstract
IgG4-related lymphadenopathy. View Abstract
Treatment of recurrent pediatric myelodysplastic syndrome post hematopoietic stem cell transplantation. View Abstract
Integration of Genomic Sequencing Drives Therapeutic Targeting of PDGFRA in T-Cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma. View Abstract
IGJ and SPATS2L immunohistochemistry sensitively and specifically identify BCR::ABL1+ and BCR::ABL1-like B-acute lymphoblastic leukaemia. View Abstract
Vascular leiomyoma of the thigh: Classic presentation of a rare tumor with imaging and pathology correlation. View Abstract
Inherited bone marrow failure syndromes and germline predisposition to myeloid neoplasia: A practical approach for the pathologist. View Abstract
Impact of cytoreduction and remission status on hematopoietic cell transplantation outcomes in pediatric myelodysplastic syndrome and related disorders. View Abstract
Immunoglobulin G4-Related Disease, Lymphadenopathy, and Lymphoma: Histopathologic Features and Diagnostic Approach. View Abstract
Old links revisited: Co-occurring thymoma and Castleman disease. View Abstract
Sporadic hyperplastic polyp associated with above-average risk of developing metachronous colorectal cancer. View Abstract
Loss of heat shock factor 1 promotes hepatic stellate cell activation and drives liver fibrosis. View Abstract
Metformin for treatment of cytopenias in children and young adults with Fanconi anemia. View Abstract
Reply to "Limitations of multivariate survival analysis". View Abstract
Impact of pretransplant mutation status on survival after allogeneic stem cell transplant for acute myeloid leukemia. View Abstract
Rapid and Deep Remission Induced by Blinatumomab for CD19-Positive Chronic Myeloid Leukemia in Lymphoid Blast Phase. View Abstract
Polyclonal PAX8 expression in carcinomas of the biliary tract - Frequent non-specific staining represents a potential diagnostic pitfall. View Abstract
CD56 expression in basaloid anal squamous cell carcinoma - A potential diagnostic pitfall. View Abstract
IgG4-related Lymphadenopathy: A Comparative Study of 41 Cases Reveals Distinctive Histopathologic Features. View Abstract
Molecular and immunophenotypic characterization of anal squamous cell carcinoma reveals distinct clinicopathologic groups associated with HPV and TP53 mutation status. View Abstract
LGR5 in Barrett's Esophagus and its Utility in Predicting Patients at Increased Risk of Advanced Neoplasia. View Abstract
A deep learning diagnostic platform for diffuse large B-cell lymphoma with high accuracy across multiple hospitals. View Abstract
Clonal IgH gene rearrangements identify Richter's transformation to diffuse large B cell lymphoma. View Abstract
Outcomes After Stereotactic Body Radiation Therapy as a Bridging Modality to Liver Transplantation for Hepatocellular Carcinoma. View Abstract
CYLD mutation characterizes a subset of HPV-positive head and neck squamous cell carcinomas with distinctive genomics and frequent cylindroma-like histologic features. View Abstract
Extramedullary Acute Myeloid Leukemia of the Renal Pelvis: Insights into a Visceral Niche. View Abstract
Resolution of Severe Graft Steatosis Before Living-Donor Liver Transplant After 86 Pounds of Weight Loss. View Abstract
Stereotactic Body Radiation Therapy for Hepatocellular Carcinoma in Patients With Child-Pugh B or C Cirrhosis. View Abstract
Frozen section diagnosis of gastrointestinal poorly cohesive and signet-ring cell adenocarcinoma: useful morphologic features to avoid misdiagnosis. View Abstract
Metastatic Signet Ring Cell Carcinoma of the Ampulla of Vater with an Unusually Prolonged Survival. View Abstract
The Use of Smartphone for Liver Graft Biopsy Assessment at the Time of Procurement. View Abstract
IgG4-related disease: review of the histopathologic features, differential diagnosis, and therapeutic approach. View Abstract
Lymphomas in IgG4-related disease: clinicopathologic features in a Western population. View Abstract
Atypical IgG4+ Plasmacytic Proliferations and Lymphomas: Characterization of 11 Cases. View Abstract
Diverse repetitive element RNA expression defines epigenetic and immunologic features of colon cancer. View Abstract
The immunophenotypic spectrum of primary mediastinal large B-cell lymphoma reveals prognostic biomarkers associated with outcome. View Abstract
PD-L1 expression in colorectal cancer is associated with microsatellite instability, BRAF mutation, medullary morphology and cytotoxic tumor-infiltrating lymphocytes. View Abstract
Amyloidosis of the liver on shear wave elastography: case report and review of literature. View Abstract
Difficult Diagnostic Problems in Pancreatobiliary Neoplasia. View Abstract
Authors’ reply. View Abstract
Smoking-associated fibrosis and pulmonary asbestosis. View Abstract
BRAF V600E immunohistochemistry is reliable in primary and metastatic colorectal carcinoma regardless of treatment status and shows high intratumoral homogeneity. View Abstract
Fine needle aspiration biopsy of an unusual follicular adenoma with sebaceous-like features. View Abstract
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