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Harry P.W. Kozakewich, MD
General Pediatric Pathology, Department of Pathology
Professor of Pathology, Harvard Medical School
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Harry P.W. Kozakewich, MD
General Pediatric Pathology, Department of Pathology
Professor of Pathology, Harvard Medical School
Medical Services
Languages
English
Education
Medical School
University of Saskatchewan College of Medicine
1967
Saskatchewan
Canada
Internship
Saint Boniface Hospital
1968
Winnipeg , Manitoba
Canada
Residency
Diagnostic Radiology
New York Hospital-Cornell Medical Center
1971
New York
NY
Residency
Pathology
Boston City Hospital
1972
Boston
MA
Residency
Anatomic Pathology and Diagnostic Radiology
Boston Children's Hospital
1975
Boston
MA
Residency
Pathology
Boston City Hospital
1976
Boston
MA
Fellowship
Oncologic Pathology
Sloan-Kettering Memorial Hospital
1978
New York
NY
Certifications
American Board of Pathology (Anatomic Cytopathology)
American Board of Radiology (Diagnostic Radiology)
Publications
BK Polyomavirus-Associated Kidney and Bladder Carcinomas Following Heart and Lung Transplantation in Childhood. View Abstract
The Natural History of Congenital Hepatic Hemangiomas. View Abstract
An endothelial SOX18-mevalonate pathway axis enables repurposing of statins for infantile hemangioma. View Abstract
Intravital Imaging of Disease Mechanisms in a Mouse Model of CCM Skin Lesions-Brief Report. View Abstract
Similarities and differences between brain and skin GNAQ p.R183Q driven capillary malformations. View Abstract
Fetal Vertebral Chondrostasis-Significance of Excessive Cartilage in Vertebral Bodies of Newborns. View Abstract
Similarities and differences between brain and skin GNAQ p.R183Q driven capillary malformations. View Abstract
Immunohistochemical Expression of Lymphatic Endothelial Markers in Blue Rubber Bleb Nevus Syndrome. View Abstract
An endothelial SOX18-mevalonate pathway axis enables repurposing of statins for infantile hemangioma. View Abstract
Papillary Hemangioma Harbors Somatic GNA11 and GNAQ Mutations. View Abstract
Kaposiform lymphangiomatosis: Diagnosis, pathogenesis, and treatment. View Abstract
Endothelial cell expression of mutant Map2k1 causes vascular malformations in mice. View Abstract
Kaposiform Lymphangiomatosis: Pathologic Aspects in 43 Patients. View Abstract
Verrucous Venous Malformation-Subcutaneous Variant. View Abstract
Prostatic metaplasia and pilar differentiation in gender-affirming mastectomy specimens. View Abstract
Congenital Disseminated Pyogenic Granuloma: Characterization of an Aggressive Multisystemic Disorder. View Abstract
Surgical Management of Fibroadipose Vascular Anomaly of the Lower Extremities. View Abstract
Intramuscular fast-flow vascular anomaly contains somatic MAP2K1 and KRAS mutations. View Abstract
Fibroadipose Vascular Anomaly in the Upper Extremity: A Distinct Entity With Characteristic Clinical, Radiological, and Histopathological Findings. View Abstract
A somatic activating NRAS variant associated with kaposiform lymphangiomatosis. View Abstract
Multimodal treatment approach in a patient with multiple intracranial myxomatous aneurysms. View Abstract
Recurrent EML4-NTRK3 fusions in infantile fibrosarcoma and congenital mesoblastic nephroma suggest a revised testing strategy. View Abstract
Somatic PIK3CA mutations are present in multiple tissues of facial infiltrating lipomatosis. View Abstract
High serum serotonin in sudden infant death syndrome. View Abstract
Intracranial myxoid mesenchymal tumors with EWSR1-CREB family gene fusions: myxoid variant of angiomatoid fibrous histiocytoma or novel entity? View Abstract
A Term Newborn with Respiratory Distress, Acidosis, and Hypoglycemia. View Abstract
Fibrous hamartoma of infancy: a clinicopathologic study of 145 cases, including 2 with sarcomatous features. View Abstract
Somatic Activating Mutations in GNAQ and GNA11 Are Associated with Congenital Hemangioma. View Abstract
Somatic Activating Mutations in GNAQ and GNA11 Are Associated with Congenital Hemangioma. View Abstract
Imaging features of kaposiform lymphangiomatosis. View Abstract
Dual role of fatty acid-binding protein 5 on endothelial cell fate: a potential link between lipid metabolism and angiogenic responses. View Abstract
Selected Diagnostically Challenging Pediatric Soft Tissue Tumors. View Abstract
Yolk Sac Tumor of the Testis in Infants and Children: A Clinicopathologic Analysis of 33 Cases. View Abstract
Impact of Screening for Hepatic Hemangiomas in Patients with Multiple Cutaneous Infantile Hemangiomas. View Abstract
Myogenic tumors in nevoid Basal cell carcinoma syndrome. View Abstract
A somatic MAP3K3 mutation is associated with verrucous venous malformation. View Abstract
Lymphatic and other vascular malformative/overgrowth disorders are caused by somatic mutations in PIK3CA. View Abstract
Villin immunohistochemistry is a reliable method for diagnosing microvillus inclusion disease. View Abstract
Rapidly involuting congenital hemangioma with fetal involution. View Abstract
Risk factors for mortality in patients with multifocal and diffuse hepatic hemangiomas. View Abstract
Cutaneovisceral angiomatosis with thrombocytopenia without cutaneous involvement. View Abstract
Abstract 63: expression of follicle-stimulating hormone receptor in vascular anomalies. View Abstract
Expression of follicle-stimulating hormone receptor in vascular anomalies. View Abstract
Abstract 75: expression of follicle-stimulating hormone receptor in vascular anomalies. View Abstract
Subfascial involvement in glomuvenous malformation. View Abstract
Intramuscular capillary-type hemangioma: radiologic-pathologic correlation. View Abstract
Fibro-adipose vascular anomaly: clinical-radiologic-pathologic features of a newly delineated disorder of the extremity. View Abstract
How are childhood thyroid nodules discovered: opportunities for improving early detection. View Abstract
Kaposiform lymphangiomatosis: a distinct aggressive lymphatic anomaly. View Abstract
Proximal tibial pain in a child. View Abstract
Proximal tibial pain in a child. View Abstract
A standardized assessment of thyroid nodules in children confirms higher cancer prevalence than in adults. View Abstract
Novel FOXF1 mutations in sporadic and familial cases of alveolar capillary dysplasia with misaligned pulmonary veins imply a role for its DNA binding domain. View Abstract
R132C IDH1 mutations are found in spindle cell hemangiomas and not in other vascular tumors or malformations. View Abstract
Gorham-Stout disease and generalized lymphatic anomaly--clinical, radiologic, and histologic differentiation. View Abstract
Pyogenic granuloma, an impaired wound healing process, linked to vascular growth driven by FLT4 and the nitric oxide pathway. View Abstract
Kaposiform hemangioendothelioma: atypical features and risks of Kasabach-Merritt phenomenon in 107 referrals. View Abstract
Recurrent atrioventricular groove intramuscular arteriovenous malformation. View Abstract
Somatic mosaic activating mutations in PIK3CA cause CLOVES syndrome. View Abstract
PTEN hamartoma of soft tissue: a distinctive lesion in PTEN syndromes. View Abstract
Congenital diaphragmatic defects: proposal for a new classification based on observations in 234 patients. View Abstract
Vascular and perivascular lesions of skin and soft tissues in children and adolescents. View Abstract
Myofibromas of the jaws in children. View Abstract
Liver hemangiomas and elevated serum a-fetoprotein: unsolved questions. View Abstract
Adrenal cortical tumors in children: factors associated with poor outcome. View Abstract
Testicular epidermoid cysts in children: sonographic characteristics with pathological correlation. View Abstract
Loss-of-function mutations in PTPN11 cause metachondromatosis, but not Ollier disease or Maffucci syndrome. View Abstract
Familial case of prenatally diagnosed intralobar and extralobar sequestrations with cystadenomatoid change. View Abstract
Histopathology of vascular anomalies. View Abstract
Thyroid pathology in PTEN-hamartoma tumor syndrome: characteristic findings of a distinct entity. View Abstract
Fatty acid-binding proteins and peribronchial angiogenesis in bronchopulmonary dysplasia. View Abstract
Primary lung tumors in children and adolescents: a 90-year experience. View Abstract
Adolescent gynecomastia: not only an obesity issue. View Abstract
p53+/mdm2- atypical lipomatous tumor/well-differentiated liposarcoma in young children: an early expression of Li-Fraumeni syndrome. View Abstract
Pulmonary pathology in thyroid transcription factor-1 deficiency syndrome. View Abstract
Effects of neoadjuvant chemotherapy on hepatoblastoma: a morphologic and immunohistochemical study. View Abstract
Founder of Pediatric Pathology. View Abstract
Childhood pancreatic tumors: a single institution experience. View Abstract
Nipple adenoma in infancy. View Abstract
Fatty acid binding protein 4 is a target of VEGF and a regulator of cell proliferation in endothelial cells. View Abstract
The presentation and management of multiple paraganglioma in head and neck. View Abstract
Congenital disseminated pyogenic granuloma. View Abstract
Macrocystic lymphatic malformation in the pulmonary parenchyma. View Abstract
Identification of signaling systems in proliferating and involuting phase infantile hemangiomas by genome-wide transcriptional profiling. View Abstract
Infantile hemangiomas involving the neuraxis: clinical and imaging findings. View Abstract
Mesenteric lipoblastoma presenting as a segmental volvulus. View Abstract
Vascular lesions of bone in children, adolescents, and young adults. A clinicopathologic reappraisal and application of the ISSVA classification. View Abstract
Hepatoblastoma presenting with focal nodular hyperplasia after treatment of neuroblastoma. View Abstract
Comparative analysis of D2-40 and LYVE-1 immunostaining in lymphatic malformations. View Abstract
A lethal form of Gorham disease associated with extensive musculoskeletal pneumatosis: case report and review of the literature. View Abstract
Osteofibrous dysplasia and adamantinoma in children and adolescents: a clinicopathologic reappraisal. View Abstract
Glucose transporter-1 protein is immunohistochemically expressed in subglottic infantile haemangioma. View Abstract
Multifocal rapidly involuting congenital hemangioma: a link to chorangioma. View Abstract
Pediatric KIT wild-type and platelet-derived growth factor receptor alpha-wild-type gastrointestinal stromal tumors share KIT activation but not mechanisms of genetic progression with adult gastrointestinal stromal tumors. View Abstract
Reticular infantile hemangioma of the limb can be associated with ventral-caudal anomalies, refractory ulceration, and cardiac overload. View Abstract
Desmoplastic small round cell tumor of the kidney in childhood. View Abstract
Hepatic hemangiomas: subtype classification and development of a clinical practice algorithm and registry. View Abstract
Bronchial atresia is common to extralobar sequestration, intralobar sequestration, congenital cystic adenomatoid malformation, and lobar emphysema. View Abstract
Verrucous hemangioma revisited. View Abstract
Cytogenetic and p53 profiles in congenital cystic adenomatoid malformation: insights into its relationship with pleuropulmonary blastoma. View Abstract
Extracellular matrix dynamics associated with tissue-engineered intravascular sclerotherapy. View Abstract
Bronchial atresia: the hidden pathology within a spectrum of prenatally diagnosed lung masses. View Abstract
D2-40 immunohistochemical analysis of pediatric vascular tumors reveals positivity in kaposiform hemangioendothelioma. View Abstract
Myogenic markers in the evaluation of embryonal botryoid rhabdomyosarcoma of the female genital tract. View Abstract
Expression of Wilms tumor 1 gene distinguishes vascular malformations from proliferative endothelial lesions. View Abstract
Balanitis xerotica obliterans in boys. View Abstract
Cytogenetic aberrations in perineurioma: variation with subtype. View Abstract
Childhood asymmetric labium majus enlargement: mimicking a neoplasm. View Abstract
Cutaneovisceral angiomatosis with thrombocytopenia. View Abstract
Myogenic markers in the evaluation of embryonal botryoid rhabdomyosarcoma of the female genital tract. View Abstract
Iliac artery stenosis in a child with cutis marmorata telangiectatica congenita. View Abstract
Vascular tumors of the heart in infants and children: case series and review of the literature. View Abstract
An injectable tissue-engineered embolus prevents luminal recanalization after vascular sclerotherapy. View Abstract
Kaposiform hemangioendothelioma without Kasabach-Merritt phenomenon. View Abstract
Heterotopic neural nodules of the scalp. View Abstract
Juvenile hyaline fibromatosis: report of a case and comparison with infantile systemic hyalinosis. View Abstract
Enhancement of intravascular sclerotherapy by tissue engineering: short-term results. View Abstract
Distinct chromosomal rearrangements in subungual (Dupuytren) exostosis and bizarre parosteal osteochondromatous proliferation (Nora lesion). View Abstract
Pathology of human metapneumovirus infection: insights into the pathogenesis of a newly identified respiratory virus. View Abstract
[Skeletal vascular lesions in childhood and adolescence]. View Abstract
Urachal inflammatory myofibroblastic tumor with ALK gene rearrangement: a study of urachal remnants. View Abstract
Abnormal distribution and hyperplasia of thyroid C-cells in PTEN-associated tumor syndromes. View Abstract
Partial oral duplication: a defect in ectomesenchymal migration? View Abstract
Rapidly involuting congenital hemangioma: clinical and histopathologic features. View Abstract
Venous malformations of skeletal muscle. View Abstract
Fast-flow lingual vascular anomalies in the young patient: is imaging diagnostic? View Abstract
A 21-year-old woman with consumptive hypothyroidism due to a vascular tumor expressing type 3 iodothyronine deiodinase. View Abstract
Angiographic features of rapidly involuting congenital hemangioma (RICH). View Abstract
PLAG1 alterations in lipoblastoma: involvement in varied mesenchymal cell types and evidence for alternative oncogenic mechanisms. View Abstract
Aggressive multimodal treatment of pleuropulmonary blastoma. View Abstract
Noninvoluting congenital hemangioma: a rare cutaneous vascular anomaly. View Abstract
Pulmonary dysplasia, Denys-Drash syndrome and Wilms tumor 1 gene mutation in twins. View Abstract
Giant cell angioblastoma: three additional occurrences of a distinct pathologic entity. View Abstract
Identification of a basal/reserve cell immunophenotype in benign and neoplastic endometrium: a study with the p53 homologue p63. View Abstract
PLAG1 fusion oncogenes in lipoblastoma. View Abstract
Severe hypothyroidism caused by type 3 iodothyronine deiodinase in infantile hemangiomas. View Abstract
Variant translocations involving 16q22 and 17p13 in solid variant and extraosseous forms of aneurysmal bone cyst. View Abstract
Clinical course of postinfectious bronchiolitis obliterans. View Abstract
Pulmonary hypertension associated with nonketotic hyperglycinaemia. View Abstract
Soft-tissue vascular anomalies: utility of US for diagnosis. View Abstract
Residual lesions after Kasabach-Merritt phenomenon in 41 patients. View Abstract
Renal cell carcinomas in children and young adults: increased incidence of papillary architecture and unique subtypes. View Abstract
Congenital mesoblastic nephroma t(12;15) is associated with ETV6-NTRK3 gene fusion: cytogenetic and molecular relationship to congenital (infantile) fibrosarcoma. View Abstract
The pericentromeric inversion, inv (6)(p25q13), is a novel diagnostic marker in chondromyxoid fibroma. View Abstract
MR lymphangiography in infants, children, and young adults. View Abstract
Pleural effusions in lymphoblastic lymphoma: a diagnostic alternative. View Abstract
Inflammatory cell distribution within and along asthmatic airways. View Abstract
The use of expandable metallic stents for acute tracheal stenosis in the growing lamb. View Abstract
Cystic neuroblastoma: emphasis on gene expression, morphology, and pathogenesis. View Abstract
Disparities in mean age and histopathologic grade between human papillomavirus type-specific early cervical neoplasms. View Abstract
Thrombocytopenic coagulopathy (Kasabach-Merritt phenomenon) is associated with Kaposiform hemangioendothelioma and not with common infantile hemangioma. View Abstract
Nephrogenic adenoma after urethral reconstruction using bladder mucosa: report of 6 cases and review of the literature. View Abstract
Localization of Tc-99m MDP in neuroblastoma metastases to the liver and lung. View Abstract
Percutaneous biopsy for prognostic testing of neuroblastoma. View Abstract
Segmental defect of the intestinal musculature of a newborn: evidence of acquired pathogenesis. View Abstract
Radiologic-pathologic conference of Children's Hospital Boston: new pulmonary nodules in a child undergoing treatment for a solid malignancy. View Abstract
Acalculous cholecystitis in children. View Abstract
Radiologic-Pathologic Conference of Children's Hospital Boston: chest wall mass in an infant with eczema. View Abstract
Splenic preservation in the management of splenic epidermoid cysts in children. View Abstract
Hepatic adenoma in the pediatric age group. Clinicopathological observations and assessment of cell proliferative activity. View Abstract
Hepatic venous blood and the development of pulmonary arteriovenous malformations in congenital heart disease. View Abstract
Lethal neonatal deficiency of carnitine palmitoyltransferase II associated with dysgenesis of the brain and kidneys. View Abstract
Increased muscularization of small pulmonary arteries in preterm infants of diabetic mothers: a morphometric study in noninflated, noninjected, routinely fixed lungs. View Abstract
Solitary nonparasitic cysts of the liver: the Boston Children's Hospital experience. View Abstract
Cytogenetic aberrations in osteosarcomas. Nonrandom deletions, rings, and double-minute chromosomes. View Abstract
Histologic correlates of vulvar human papillomavirus infection in children and young adults. View Abstract
Cellular markers that distinguish the phases of hemangioma during infancy and childhood. View Abstract
Identification of genetically aberrant cell lineages in Wilms' tumors. View Abstract
The anatomy of Cupid's bow in normal and cleft lip. View Abstract
Prenatal detection of neuroblastoma: a ten-year experience from the Dana-Farber Cancer Institute and Children's Hospital. View Abstract
Wilms tumor and nephroblastomatosis: imaging characteristics at gadolinium-enhanced MR imaging. View Abstract
Effects of interleukin-3 and granulocyte-macrophage colony-stimulating factor on thrombopoiesis in congenital amegakaryocytic thrombocytopenia. View Abstract
Metastatic ovarian tumors in children: a report of 14 cases and review of the literature. View Abstract
Stage III neuroblastoma over 1 year of age at diagnosis: improved survival with intensive multimodality therapy including multiple alkylating agents. View Abstract
Cytogenetic findings in pediatric adipose tumors: consistent rearrangement of chromosome 8 in lipoblastoma. View Abstract
Dermatoglyphics in sudden infant death syndrome. View Abstract
Adrenocortical neoplasms in childhood and adolescence: Analysis of prognostic factors including DNA content. View Abstract
Perforation of the augmented bladder. View Abstract
Adrenal cortical neoplasms in the pediatric and adolescent age group. Clinicopathologic study of 30 cases with emphasis on epidemiological and prognostic factors. View Abstract
Surgical management of stage III and IV neuroblastoma: resection before or after chemotherapy? View Abstract
Diagnostic relevance of clonal cytogenetic aberrations in malignant soft-tissue tumors. View Abstract
Osteosarcoma in young children. View Abstract
Consistent cytogenetic aberrations in hepatoblastoma: a common pathway of genetic alterations in embryonal liver and skeletal muscle malignancies? View Abstract
Undifferentiated (embryonal) sarcoma of the liver. Clinical and pathologic study of 16 cases with emphasis on immunohistochemical features. View Abstract
Percutaneous biopsy of thoracic lesions in children. View Abstract
Chronic recurrent multifocal osteomyelitis. Association with vertebra plana. View Abstract
Fate of the distal esophageal remnant following esophageal replacement. View Abstract
Peritoneal inclusion cysts: ovarian fluid in peritoneal adhesions. View Abstract
Case report 507: Osteosarcoma of the distal femoral epiphysis. View Abstract
Characterization of airway mucus from a fatal case of status asthmaticus. View Abstract
Myocardial contraction band lesions in patients with fatal asthma: possible neurocardiologic mechanisms. View Abstract
Central giant cell lesions of the jaws: a clinicopathologic study. View Abstract
Primary lymphoma of bone in children: analysis of treatment results with adriamycin, prednisone, Oncovin (APO), and local radiation therapy. View Abstract
An hepatic metabolic profile in sudden infant death (SIDS). View Abstract
Adamantinoma of the tibia. An ultrastructural and immunohistochemical study. View Abstract
Large-cell calcifying sertoli cell tumor of the testis. An ultrastructural, immunocytochemical, and biochemical study. View Abstract
The sinus node in sudden infant death syndrome. View Abstract
Sacrococcygeal germ cell tumors in childhood: an updated experience with 118 patients. View Abstract
Growth pattern and differentiation of human soft tissue sarcomas in nude mice. View Abstract
Recurring digital fibrous tumor of childhood [proceedings]. View Abstract
Congenital megacalyces. View Abstract
Opacification of the mediastinal nodes by the intrapleural injection of two types of emulsions. Study of their effect upon the pleura. View Abstract
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