Elizabeth Blume, MD
Division Chief, Advanced Cardiac Therapies; Senior Cardiologist, Department of Cardiology
Professor of Pediatrics, Harvard Medical School
Image
Elizabeth Blume, MD
Division Chief, Advanced Cardiac Therapies; Senior Cardiologist, Department of Cardiology
Professor of Pediatrics, Harvard Medical School
Medical Services
Languages
English
Education
Undergraduate School
Brown University
1986
Providence
RI
Medical School
Case Western Reserve University
1991
Cleveland
OH
Residency
Boston Children's Hospital
1994
Boston
MA
Fellowship
Boston Children's Hospital
1997
Boston
MA
Certifications
American Board of Pediatrics (Cardiology)
Publications
Donor History of Drug Use and Graft Survival in Pediatric Heart Transplant Recipients. View Abstract
Ventricular Assist Device Utilization for Children With Congenital Heart Disease: Still Bridging the Gap. View Abstract
From worries to resilience: a qualitative study of the psychosocial experiences of diverse adolescents and young adults with heart failure and their caregivers. View Abstract
Teaching pediatric cardiology fellows to communicate serious news: a pilot study. View Abstract
Socioeconomic Status and Major Adverse Transplant Events in Pediatric Heart Transplant Recipients. View Abstract
Pathology of explanted pediatric hearts: An 11-year study. Population characteristics and implications for outcomes. View Abstract
The experience of fathers of children hospitalised with advanced heart disease. View Abstract
The Conduit to Improving Outcomes: Supporting the Vulnerable Myocardium in Hypoplastic Left Heart Syndrome. View Abstract
The family burden of paediatric heart disease during the chronic phase of illness. View Abstract
Medium-term Outcomes in Pediatric Heart Transplant Recipients Managed Using a Steroid Avoidance Immune Suppression Protocol. View Abstract
The roles of preparation, location, and palliative care involvement in parent-perceived child suffering at the end of life. View Abstract
The 2023 International Society for Heart and Lung Transplantation Guidelines for Mechanical Circulatory Support: A 10- Year Update. View Abstract
Medical and End-of-Life Decision-Making Preferences in Adolescents and Young Adults with Advanced Heart Disease and Their Parents. View Abstract
Apixaban Anticoagulation in Children and Young Adults Supported With the HeartMate 3 Ventricular Assist Device. View Abstract
Patient and parent-reported outcomes in paediatric ventricular assist device support: a multi-center ACTION learning network feasibility and pilot experience. View Abstract
Palliative Care Across the Life Span for Children With Heart Disease: A Scientific Statement From the American Heart Association. View Abstract
Finding the Words and Data to Discuss Donor Characteristics With Heart Transplant Recipients and Families: Reconsidering Risk. View Abstract
Prognostic Value of Exercise Stress Echocardiography in Pediatric Cardiac Transplant Recipients. View Abstract
Parent-Provider Communication in Hospitalized Children with Advanced Heart Disease. View Abstract
The Surprise Question as a Trigger for Primary Palliative Care Interventions for Children with Advanced Heart Disease. View Abstract
Assessment of an Instrument to Measure Interdisciplinary Staff Perceptions of Quality of Dying and Death in a Pediatric Cardiac Intensive Care Unit. View Abstract
Pediatric heart transplant waiting times in the United States since the 2016 allocation policy change. View Abstract
Obesity and dyslipidemia predict cardiac allograft vasculopathy and graft loss in children and adolescents post-heart transplant: A PHTS multi-institutional analysis. View Abstract
Self-reported quality of life in children with ventricular assist devices. View Abstract
Design and pilot testing of therapeutic clothing for hospitalized children. View Abstract
A "Good Death" for Children with Cardiac Disease. View Abstract
Circumstances surrounding end-of-life in pediatric patients pre- and post-heart transplant: a report from the Pediatric Heart Transplant Society. View Abstract
Native Bicuspid Pulmonary Valve in D-Loop Transposition of the Great Arteries: Outcomes of the Neo-Aortic Valve Function and Root Dilation After Arterial Switch Operation. View Abstract
Parent-Reported Symptoms and Perceived Effectiveness of Treatment in Children Hospitalized with Advanced Heart Disease. View Abstract
State of the science and future research directions in palliative and end-of-life care in paediatric cardiology: a report from the Harvard Radcliffe Accelerator Workshop. View Abstract
ISHLT consensus statement for the selection and management of pediatric and congenital heart disease patients on ventricular assist devices Endorsed by the American Heart Association. View Abstract
Burnout, professional fulfillment, and post-traumatic stress among pediatric solid organ transplant teams. View Abstract
Palliative Care Referrals in Cardiac Disease. View Abstract
Parent and Physician Understanding of Prognosis in Hospitalized Children With Advanced Heart Disease. View Abstract
Variability in clinical decision-making for ventricular assist device implantation in pediatrics. View Abstract
Fourth Annual Pediatric Interagency Registry for Mechanical Circulatory Support (Pedimacs) Report. View Abstract
Comparison of tissue Doppler imaging and conventional echocardiography to discriminate rejection from non-rejection after pediatric heart transplantation. View Abstract
The re-occurrence of cardiomyopathy in propionic acidemia after liver transplantation. View Abstract
Extracorporeal Membrane Oxygenation Support After Heart Transplantation in Children-Outcomes of a Single Center Cohort. View Abstract
Three-Dimensional Speckle Tracking Echocardiography for Assessment of Left Ventricular Function and Myocardial Mechanics after Pediatric Heart Transplantation. View Abstract
"How are You Doing?": Patient and Family Support Resources for Children on Ventricular Assist Device. View Abstract
Obesity Leads to Increased Mortality in Pediatric Heart Transplant Recipients - A Pediatric Heart Transplant Society Study. View Abstract
Association of Clinical Rejection Versus Rejection on Protocol Biopsy With Cardiac Allograft Vasculopathy in Pediatric Heart Transplant Recipients. View Abstract
Fears and Stressors of Trainees Starting Fellowship in Pediatric Cardiology. View Abstract
Medical and end-of-life decision making in adolescents' pre-heart transplant: A descriptive pilot study. View Abstract
Congenital Cardiothoracic Surgeons and Palliative Care: A National Survey Study. View Abstract
Integration of Pediatric Palliative Care Into Cardiac Intensive Care: A Champion-Based Model. View Abstract
Phenotypic Manifestations of Arrhythmogenic Cardiomyopathy in Children and Adolescents. View Abstract
Is Doppler echocardiography useful for estimating left ventricular filling pressures in pediatric heart transplant recipients? View Abstract
Early outcomes for low-risk pediatric heart transplant recipients and steroid avoidance: A multicenter cohort study (Clinical Trials in Organ Transplantation in Children - CTOTC-04). View Abstract
Palliative care and paediatric cardiology: current evidence and future directions. View Abstract
Third Annual Pediatric Interagency Registry for Mechanical Circulatory Support (Pedimacs) Report: Preimplant Characteristics and Outcomes. View Abstract
Compassionate deactivation of ventricular assist devices in children: A survey of pediatric ventricular assist device clinicians' perspectives and practices. View Abstract
When a Child Needs a Transplant but Lacks Familial Social Support. View Abstract
Ventricular Assist Device Support as a Bridge to Transplantation in Pediatric Patients. View Abstract
Pediatric heart transplantation across a positive crossmatch: First year results from the CTOTC-04 multi-institutional study. View Abstract
Incidence, characterization, and impact of newly detected donor-specific anti-HLA antibody in the first year after pediatric heart transplantation: A report from the CTOTC-04 study. View Abstract
Study rationale, design, and pretransplantation alloantibody status: A first report of Clinical Trials in Organ Transplantation in Children-04 (CTOTC-04) in pediatric heart transplantation. View Abstract
Physician Perspectives on Palliative Care for Children with Advanced Heart Disease: A Comparison between Pediatric Cardiology and Palliative Care Physicians. View Abstract
Post-transplant outcomes in pediatric ventricular assist device patients: A PediMACS-Pediatric Heart Transplant Study linkage analysis. View Abstract
Liver abnormalities and post-transplant survival in pediatric Fontan patients. View Abstract
Homozygous EEF1A2 mutation causes dilated cardiomyopathy, failure to thrive, global developmental delay, epilepsy and early death. View Abstract
Patterns and Outcomes of Care in Children With Advanced Heart Disease Receiving Palliative Care Consultation. View Abstract
Eighth annual INTERMACS report: Special focus on framing the impact of adverse events. View Abstract
Second annual Pediatric Interagency Registry for Mechanical Circulatory Support (Pedimacs) report: Pre-implant characteristics and outcomes. View Abstract
Pediatric Cardiology Provider Attitudes About Palliative Care: A Multicenter Survey Study. View Abstract
The Evolution of a Pediatric Ventricular Assist Device Program: The Boston Children's Hospital Experience. View Abstract
Deactivation of Ventricular Assist Devices: Perspectives and Experiences of Adult Cardiovascular Providers. View Abstract
Outcomes following implantation of mechanical circulatory support in adults with congenital heart disease: An analysis of the Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS). View Abstract
Trans-Fontan baffle placement of an endocardial systemic ventricular pacing lead. View Abstract
Does Small Size Matter With Continuous Flow Devices?: Analysis of the INTERMACS Database of Adults With BSA =1.5 m2. View Abstract
Vascular endothelial growth factor A is associated with the subsequent development of moderate or severe cardiac allograft vasculopathy in pediatric heart transplant recipients. View Abstract
Palliative Care for Patients With End-Stage Cardiovascular Disease and Devices: A Report From the Palliative Care Working Group of the Geriatrics Section of the American College of Cardiology. View Abstract
Is Endomyocardial Biopsy a Safe and Useful Procedure in Children with Suspected Cardiomyopathy? View Abstract
Report of the National Heart, Lung, and Blood Institute Working Group: An Integrated Network for Congenital Heart Disease Research. View Abstract
Adverse events in children implanted with ventricular assist devices in the United States: Data from the Pediatric Interagency Registry for Mechanical Circulatory Support (PediMACS). View Abstract
Outcomes of children implanted with ventricular assist devices in the United States: First analysis of the Pediatric Interagency Registry for Mechanical Circulatory Support (PediMACS). View Abstract
Outcomes of pediatric patients supported with continuous-flow ventricular assist devices: A report from the Pediatric Interagency Registry for Mechanical Circulatory Support (PediMACS). View Abstract
Is Myocarditis an Independent Risk Factor for Post-Transplant Mortality in Pediatric Heart Transplant Recipients? View Abstract
Seventh INTERMACS annual report: 15,000 patients and counting. View Abstract
Pediatric mechanical circulatory support: available devices and outcomes as bridge-to-transplant therapy. View Abstract
Physician and parent perceptions of prognosis and end-of-life experience in children with advanced heart disease. View Abstract
Adrenergic receptor genotype influences heart failure severity and ß-blocker response in children with dilated cardiomyopathy. View Abstract
Association of hemodynamic profiles with wait-list mortality in children listed for heart transplantation with idiopathic dilated cardiomyopathy. View Abstract
Treatment and outcomes of immune cytopenias following solid organ transplant in children. View Abstract
Parental perspectives on suffering and quality of life at end-of-life in children with advanced heart disease: an exploratory study*. View Abstract
Risk factors and outcome of Fontan-associated plastic bronchitis: a case-control study. View Abstract
Sixth INTERMACS annual report: a 10,000-patient database. View Abstract
Ventricular assist devices in children: progress with an orphan device application. View Abstract
Survival in patients removed from the heart transplant waiting list before receiving a transplant. View Abstract
Tissue Doppler imaging for rejection surveillance in pediatric heart transplant recipients. View Abstract
Antibody depletion for the treatment of crossmatch-positive pediatric heart transplant recipients. View Abstract
Prognostic value of exercise testing during heart transplant evaluation in children. View Abstract
Ten yr of pediatric heart transplantation: a report from the Pediatric Heart Transplant Study. View Abstract
Cardiovascular outcomes after the arterial switch operation for D-transposition of the great arteries. View Abstract
Statement regarding the pre and post market assessment of durable, implantable ventricular assist devices in the United States. View Abstract
Statement regarding the pre and post market assessment of durable, implantable ventricular assist devices in the United States: executive summary. View Abstract
Statement regarding the pre and post market assessment of durable, implantable ventricular assist devices in the United States. View Abstract
Statement regarding the pre and post market assessment of durable, implantable ventricular assist devices in the United States: executive summary. View Abstract
Statement regarding the pre and post market assessment of durable, implantable ventricular assist devices in the United States. View Abstract
Cardiac allograft function during the first year after transplantation in rejection-free children and young adults. View Abstract
Allograft-Transmitted Histoplasma capsulatum Infection in a Solid Organ Transplant Recipient. View Abstract
Patterns of care at end of life in children with advanced heart disease. View Abstract
Utility of exercise stress echocardiography in pediatric cardiac transplant recipients: a single-center experience. View Abstract
Endomyocardial biopsy and selective coronary angiography are low-risk procedures in pediatric heart transplant recipients: results of a multicenter experience. View Abstract
Comparison of risk factors and outcomes for pediatric patients listed for heart transplantation after bidirectional Glenn and after Fontan: an analysis from the Pediatric Heart Transplant Study. View Abstract
Sudden death after pediatric heart transplantation: analysis of data from the Pediatric Heart Transplant Study Group. View Abstract
Berlin Heart EXCOR Pediatric ventricular assist device Investigational Device Exemption study: study design and rationale. View Abstract
Association of graft ischemic time with survival after heart transplant among children in the United States. View Abstract
Outcomes after listing for primary transplantation for infants with unoperated-on non-hypoplastic left heart syndrome congenital heart disease: a multi-institutional study. View Abstract
The impact of heart failure severity at time of listing for cardiac transplantation on survival in pediatric cardiomyopathy. View Abstract
Changes in echocardiographic measures of systolic and diastolic function in children 1 year after hematopoietic SCT. View Abstract
Patterns of End-of-Life Care in Children with Advanced Heart Disease (747). View Abstract
Infection and malignancy after pediatric heart transplantation: the role of induction therapy. View Abstract
Rejection with hemodynamic compromise in the current era of pediatric heart transplantation: a multi-institutional study. View Abstract
Minimizing infection and rejection death: clues acquired from 19 years of multi-institutional cardiac transplantation data. View Abstract
Association of race and socioeconomic position with outcomes in pediatric heart transplant recipients. View Abstract
Outcomes of heart transplantation using donor hearts from infants with sudden infant death syndrome. View Abstract
BNP levels predict outcome in pediatric heart failure patients: post hoc analysis of the Pediatric Carvedilol Trial. View Abstract
Impact of ABO-incompatible listing on wait-list outcomes among infants listed for heart transplantation in the United States: a propensity analysis. View Abstract
Decline in rejection in the first year after pediatric cardiac transplantation: a multi-institutional study. View Abstract
Use of a virtual community as a psychosocial support system in pediatric transplantation. View Abstract
Safety and early outcomes using a corticosteroid-avoidance immunosuppression protocol in pediatric heart transplant recipients. View Abstract
Racial and ethnic differences in mortality in children awaiting heart transplant in the United States. View Abstract
Incidence and risk factors for mortality in infants awaiting heart transplantation in the USA. View Abstract
Evaluating failing Fontans for heart transplantation: predictors of death. View Abstract
Socioeconomic position and graft failure in pediatric heart transplant recipients. View Abstract
Waiting list mortality among children listed for heart transplantation in the United States. View Abstract
Predictors of death and transplant in patients with a mechanical circulatory support device: a multi-institutional study. View Abstract
The longitudinal course of cardiomyopathy in Friedreich's ataxia during childhood. View Abstract
Ventricular assist devices as a bridge to heart transplantation in children. View Abstract
Intra-aortic balloon pump use in the failing Fontan circulation. View Abstract
Longitudinal changes in heart rate recovery after maximal exercise in pediatric heart transplant recipients: evidence of autonomic re-innervation? View Abstract
Carvedilol for children and adolescents with heart failure: a randomized controlled trial. View Abstract
Outcome after Fontan failure and takedown to an intermediate palliative circulation. View Abstract
Parenting stress and parental post-traumatic stress disorder in families after pediatric heart transplantation. View Abstract
Indications for heart transplantation in pediatric heart disease: a scientific statement from the American Heart Association Council on Cardiovascular Disease in the Young; the Councils on Clinical Cardiology, Cardiovascular Nursing, and Cardiovascular Surgery and Anesthesia; and the Quality of Care and Outcomes Research Interdisciplinary Working Group. View Abstract
Successful use of bivalirudin for cardiac transplantation in a child with heparin-induced thrombocytopenia. View Abstract
Outcome of listing for cardiac transplantation for failed Fontan: a multi-institutional study. View Abstract
Successful implantation of a Berlin heart biventricular assist device in a failing single ventricle. View Abstract
Outcomes of children bridged to heart transplantation with ventricular assist devices: a multi-institutional study. View Abstract
Prospective single-arm protocol of carvedilol in children with ventricular dysfunction. View Abstract
Lymphoproliferative disorders after paediatric heart transplantation: a multi-institutional study. View Abstract
International Society for Heart and Lung Transplantation: Practice guidelines for management of heart failure in children. View Abstract
The longitudinal impact of psychological functioning, medical severity, and family functioning in pediatric heart transplantation. View Abstract
Risk factors for recurrent rejection in pediatric heart transplantation: a multicenter experience. View Abstract
Current status of heart transplantation in children: update 2003. View Abstract
Atrial tachyarrhythmias and permanent pacing after pediatric heart transplantation. View Abstract
Extracorporeal membrane oxygenation as a bridge to cardiac transplantation in a patient with cardiomyopathy and hemophilia A. View Abstract
Gastrointestinal complications after pediatric cardiac transplantation. View Abstract
Arterial switch operation with a single coronary artery. View Abstract
Endothelial COX-2 induction by hypoxia liberates 6-keto-PGF1 alpha, a potent epithelial secretagogue. View Abstract
Giant cell myocarditis in a 12-year-old girl with common variable immunodeficiency. View Abstract
Perioperative risk factors for development of protein-losing enteropathy following a Fontan procedure. View Abstract
Carvedilol as therapy in pediatric heart failure: an initial multicenter experience. View Abstract
Clinical outcome of fenestrated Fontan patients after closure: the first 10 years. View Abstract
Sialyl LewisX oligosaccharide preserves myocardial and endothelial function during cardioplegic ischemia. View Abstract
Long-term follow-up of pediatric cardiac patients requiring mechanical circulatory support. View Abstract
Left superior vena cava connection to unroofed coronary sinus associated with positional cyanosis: successful transcatheter treatment using Gianturco-Grifka vascular occlusion device. View Abstract
Sodium channel abnormalities are infrequent in patients with long QT syndrome: identification of two novel SCN5A mutations. View Abstract
Evolution of risk factors influencing early mortality of the arterial switch operation. View Abstract
Activated endothelial cells elicit paracrine induction of epithelial chloride secretion. 6-Keto-PGF1alpha is an epithelial secretagogue. View Abstract
Images in cardiovascular medicine. Anatomically corrected malposition of the great arteries [S,D,L]. View Abstract
Long-term results of arterial switch repair of transposition of the great vessels. View Abstract
Soluble adhesion molecules in infants and children undergoing cardiopulmonary bypass. View Abstract
A switch in time saves a statistical bind. View Abstract
Amnesic patients give clues on structure of memory. View Abstract
Palliation may block cure of incontinence in elderly. View Abstract
Elderly patient needs assessment, not neglect. View Abstract
Street drugs yield primate Parkinson's model. View Abstract
Premenstrual syndromes, depression linked. View Abstract
Sound, shock waves shatter kidney stones. View Abstract
Ambulatory dialysis: special boon for children. View Abstract
'Tricks' of trade aid kidney transplants. View Abstract
Promising agents for limiting renal damage. View Abstract
Locations