Elena Crestani, MD

Immunologist, Allergy and Asthma Program
Assistant Professor of Pediatrics, Harvard Medical School
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Elena Crestani, MD

Elena Crestani, MD

Immunologist, Allergy and Asthma Program
Assistant Professor of Pediatrics, Harvard Medical School

Medical Services

Languages
English
Education
Medical School
University of Verona
2000
Verona
Italy
Graduate School
University of Texas Health Science Center
2006
Houston
TX
Residency
University of Texas Health Science Center
2011
Houston
TX
Fellowship
Boston Children's Hospital
2015
Boston
MA
Certifications
American Board of Pediatrics (General)
American Board of Allergy & Immunology (General)

Publications

RELMß sets the threshold for microbiome-dependent oral tolerance. View Abstract
Notch4 regulatory T cells and SARS-CoV-2 viremia shape COVID19 survival outcome. View Abstract
An Atypical Case of Parotid Swelling. View Abstract
Age-specific Metabolomic profiles in children with food allergy. View Abstract
Piloting a multidisciplinary group education session to support caregivers of children with food protein-induced enterocolitis syndrome (FPIES). View Abstract
The Notch1/CD22 signaling axis disrupts Treg function in SARS-CoV-2-associated multisystem inflammatory syndrome in children. View Abstract
SARS-CoV-2-specific T cell responses in patients with multisystem inflammatory syndrome in children. View Abstract
A common IL-4 receptor variant promotes asthma severity via a Treg cell GRB2-IL-6-Notch4 circuit. View Abstract
Atopic Dermatitis Mediates the Association Between an IL4RA Variant and Food Allergy in School-Aged Children. View Abstract
Notch1-CD22-Dependent Immune Dysregulation in the SARS-CoV2-Associated Multisystem Inflammatory Syndrome in Children. View Abstract
A virus-specific monocyte inflammatory phenotype is induced by SARS-CoV-2 at the immune-epithelial interface. View Abstract
Author Correction: A regulatory T cell Notch4-GDF15 axis licenses tissue inflammation in asthma. View Abstract
Notch4 signaling limits regulatory T-cell-mediated tissue repair and promotes severe lung inflammation in viral infections. View Abstract
Author Correction: A regulatory T cell Notch4-GDF15 axis licenses tissue inflammation in asthma. View Abstract
Regulatory T Cell-Derived TGF-ß1 Controls Multiple Checkpoints Governing Allergy and Autoimmunity. View Abstract
Regulatory T Cell-Derived TGF-ß1 Controls Multiple Checkpoints Governing Allergy and Autoimmunity. View Abstract
Practical Guidance for the Evaluation and Management of Drug Hypersensitivity: Specific Drugs. View Abstract
A regulatory T cell Notch4-GDF15 axis licenses tissue inflammation in asthma. View Abstract
Dietary and Microbial Determinants in Food Allergy. View Abstract
Untargeted metabolomic profiling identifies disease-specific signatures in food allergy and asthma. View Abstract
Author Correction: Microbiota therapy acts via a regulatory T cell MyD88/ROR?t pathway to suppress food allergy. View Abstract
Heterozygous FOXN1 Variants Cause Low TRECs and Severe T Cell Lymphopenia, Revealing a Crucial Role of FOXN1 in Supporting Early Thymopoiesis. View Abstract
Microbiota therapy acts via a regulatory T cell MyD88/ROR?t pathway to suppress food allergy. View Abstract
Systemic Reactions in Pediatric Patients Receiving Standardized Allergen Subcutaneous Immunotherapy with and without Seasonal Dose Adjustment. View Abstract
Efficacy and Safety of AR101 in Oral Immunotherapy for Peanut Allergy: Results of ARC001, a Randomized, Double-Blind, Placebo-Controlled Phase 2 Clinical Trial. View Abstract
Dual T cell- and B cell-intrinsic deficiency in humans with biallelic RLTPR mutations. View Abstract
Autoimmune lymphoproliferative syndrome caused by a homozygous FasL mutation that disrupts FasL assembly. View Abstract
Broad spectrum of autoantibodies in patients with Wiskott-Aldrich syndrome and X-linked thrombocytopenia. View Abstract
RAG1 deficiency may present clinically as selective IgA deficiency. View Abstract
IgE-mediated hypersensitivity reaction and desensitization to glatiramer acetate in a pediatric patient. View Abstract
RAG1 reversion mosaicism in a patient with Omenn syndrome. View Abstract
Association of IL-5 cytokine production and in vivo IgE levels in infants and parents. View Abstract
Exhaled air temperature in asthma: methods and relationship with markers of disease. View Abstract
Parental asthma as a risk factor for the development of early skin test sensitization in children. View Abstract
Fractionated total body irradiation in bone marrow transplantation--an emphasis on lung dosimetry. View Abstract