Carol E. Barnewolt, MD

Staff Radiologist, Department of Radiology
Assistant Professor of Radiology, Harvard Medical School
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Carol E. Barnewolt, MD

Carol E. Barnewolt, MD

Staff Radiologist, Department of Radiology
Assistant Professor of Radiology, Harvard Medical School
Education
Undergraduate School
Santa Clara University
1983
Santa Clara
CA
Medical School
Chicago Medical School
1987
Chicago
IL
Internship
UCSF Valley Medical Center of Fresno
1988
Fresno
CA
Residency
UCSF - Fresno Hospitals
1992
Fresno
CA
Fellowship
Boston Children's Hospital
1994
Boston
MA
Certifications
American Board of Radiology (Pediatric Radiology)
American Board of Radiology (Diagnostic Radiology)
Professional History

I have been a full-time radiology faculty member since 1994.  Areas of interest were broad initially and have gradually become more concentrated in the areas of integrated fetal and pediatric genitourinary imaging and ultrasound/MRI correlation.  This has led to a close relationship and collaboration with pediatric gynecology, urology, general surgery, rheumatology, orthopedic, and fetal subspecialists in daily problem solving.  My work centers around the Advanced Fetal Care Center at Children's Hospital and the development of techniques in fetal imaging as a natural extension of expertise in the field of Pediatric Radiology.  Our goal is to cultivate a center that supports families faced with anomalous pregnancies beginning with accurate, precise diagnosis, connection with appropriate subspecialties, counseling, delivery, treatment, and health care throughout childhood.

Approach to Care
My goal is to provide thoughtful, individualized imaging evaluation of the fetus, infant, and child through direct collaboration with the patient, family, sonographers/technologists, referring clinicians, and subspecialists, while minimizing cost and exposure to risks such as ionizing radiation and sedation/anesthesia.

Publications

Accuracy of contrast-enhanced voiding urosonography using Optison™ for diagnosis of vesicoureteral reflux in children. View Abstract
Refining sonographic criteria for paediatric appendicitis: combined effects of age-based appendiceal size and secondary findings. View Abstract
Ultrasound Assessment of Quadriceps Femoris Muscle Thickness in Critically Ill Children. View Abstract
Contrast-enhanced ultrasound of the spleen, pancreas and gallbladder in children. View Abstract
Contrast-enhanced voiding urosonography part 2: urethral imaging. View Abstract
Does age affect the test performance of secondary sonographic findings for pediatric appendicitis? View Abstract
Contrast-enhanced ultrasound of pediatric lungs. View Abstract
Contrast-enhanced ultrasound for musculoskeletal indications in children. View Abstract
Contrast-enhanced ultrasound of the pediatric brain. View Abstract
Contrast enhanced colostography: New applications in preoperative evaluation of anorectal malformations. View Abstract
Leveraging the Combined Predictive Value of Ultrasound and Laboratory Data to Reduce Radiation Exposure and Resource Utilization in Children with Suspected Appendicitis. View Abstract
Fetal Echoplanar Imaging: Promises and Challenges. View Abstract
Interobserver and Intra-Observer Reliability of the Urinary Tract Dilation Classification System in Neonates: A Multicenter Study. View Abstract
The association of postnatal urinary tract dilation risk score with clinical outcomes. View Abstract
Prenatal imaging throughout gestation in Beckwith-Wiedemann syndrome. View Abstract
A new variant of type III jejunoileal atresia. View Abstract
The Distended Fetal Hypopharynx: A Sensitive and Novel Sign for the Prenatal Diagnosis of Esophageal Atresia. View Abstract
Pediatric contrast-enhanced ultrasound in the United States: a survey by the Contrast-Enhanced Ultrasound Task Force of the Society for Pediatric Radiology. View Abstract
Early Outcomes of Vein Grafting for Reconstruction of Brachial Arterial Injuries in Children. View Abstract
Radiographic measurement of intestinal length among children with short bowel syndrome: Retrospective determination remains problematic. View Abstract
Erratum to "Creation and Validation of a Simulator for Neonatal Brain Ultrasonography: A Pilot Study": [Acad Radiol 2017; 24:76-83]. View Abstract
Percent predicted lung volume changes on fetal magnetic resonance imaging throughout gestation in congenital diaphragmatic hernia. View Abstract
Teratoma of the neonatal head and neck: A 41-year experience. View Abstract
Creation and Validation of a Simulator for Neonatal Brain Ultrasonography: A Pilot Study. View Abstract
Intrarenal Reflux: Diagnosis at Contrast-Enhanced Voiding Urosonography. View Abstract
Residual intravesical iodinated contrast: a potential cause of false-negative reflux study at contrast-enhanced voiding urosonography. View Abstract
Fetal lung apparent diffusion coefficient measurement using diffusion-weighted MRI at 3 Tesla: Correlation with gestational age. View Abstract
Fetal MRI: A Technical Update with Educational Aspirations. View Abstract
Utility of ultrasound in the diagnosis of polycystic ovary syndrome in adolescents. View Abstract
Human fetal sacrococcygeal extension or 'tail' in the second trimester: prenatal diagnosis, associated findings, and clinical outcome. View Abstract
A prospective study of expectant observation as primary therapy for neuroblastoma in young infants: a Children's Oncology Group study. View Abstract
Identifying ureteropelvic junction obstruction by fluorescence imaging: a comparative study of imaging modalities to assess renal function and degree of obstruction in a mouse model. View Abstract
Serial amnioinfusions prevent fetal pulmonary hypoplasia in a large animal model of oligohydramnios. View Abstract
Frequency and cause of disagreements in imaging diagnosis in children with ventriculomegaly diagnosed prenatally. View Abstract
Fetal brain volumetry through MRI volumetric reconstruction and segmentation. View Abstract
Correlation between prenatal urinary matrix metalloproteinase activity and the degree of kidney damage in a large animal model of congenital obstructive uropathy. View Abstract
Neurodevelopmental outcome of fetuses referred for ventriculomegaly. View Abstract
Posthemorrhagic cerebellar disruption mimicking Dandy-Walker malformation: fetal imaging and neuropathology findings. View Abstract
Prenatal urinary matrix metalloproteinase profiling as a potential diagnostic tool in fetal obstructive uropathy. View Abstract
Prenatal diagnosis and treatment of congenital differences of the hand and upper limb. View Abstract
Differential risk for neonatal surgical airway intervention in prenatally diagnosed neck masses. View Abstract
Pediatric radiation exposure and effective dose reduction during voiding cystourethrography. View Abstract
In utero treatment for bladder outlet obstruction using robot assisted laparoscopic techniques. View Abstract
Prenatal diagnosis and subsequent treatment of an intermediate-risk paraspinal neuroblastoma: case report and review of the literature. View Abstract
How accurately does current fetal imaging identify posterior fossa anomalies? View Abstract
Frequency and cause of disagreements in diagnoses for fetuses referred for ventriculomegaly. View Abstract
Liver position is a prenatal predictive factor of prosthetic repair in congenital diaphragmatic hernia. View Abstract
Prenatal diagnosis of thoracic ectopia cordis by real-time fetal cardiac magnetic resonance imaging and by echocardiography. View Abstract
Large fetal congenital cystic adenomatoid malformations: growth trends and patient survival. View Abstract
Ex utero intrapartum treatment with placement on extracorporeal membrane oxygenation for fetal thoracic masses. View Abstract
Ex utero intrapartum treatment with extracorporeal membrane oxygenation for severe congenital diaphragmatic hernia. View Abstract
Percent predicted lung volumes as measured on fetal magnetic resonance imaging: a useful biometric parameter for risk stratification in congenital diaphragmatic hernia. View Abstract
Bronchial atresia is common to extralobar sequestration, intralobar sequestration, congenital cystic adenomatoid malformation, and lobar emphysema. View Abstract
Fetal lung volume measurements: determination with MR imaging--effect of various factors. View Abstract
Cleft of the secondary palate without cleft lip diagnosed with three-dimensional ultrasound and magnetic resonance imaging in a fetus with Fryns' syndrome. View Abstract
Diagnosis of inferior vermian hypoplasia by fetal magnetic resonance imaging: potential pitfalls and neurodevelopmental outcome. View Abstract
Fetal sheep development on ultrasound and magnetic resonance imaging: a standard for the in utero assessment of models of congenital abnormalities. View Abstract
Radiation exposure reduction during voiding cystourethrography in a pediatric porcine model of vesicoureteral reflux. View Abstract
Bronchial atresia: the hidden pathology within a spectrum of prenatally diagnosed lung masses. View Abstract
Magnetic resonance imaging of pelvic musculoskeletal and genitourinary anatomy in patients before and after complete primary repair of bladder exstrophy. View Abstract
Fetal surgery in otolaryngology: a new era in the diagnosis and management of fetal airway obstruction because of advances in prenatal imaging. View Abstract
Pediatric ceftriaxone nephrolithiasis. View Abstract
Oropharyngeal teratoma: prenatal diagnosis and assessment using sonography, MRI, and CT with management by ex utero intrapartum treatment procedure. View Abstract
Validation of a clinical prediction rule for the differentiation between septic arthritis and transient synovitis of the hip in children. View Abstract
Prenatal diagnosis of cleft lip and cleft palate using MRI. View Abstract
Sonography of the fetal central nervous system. View Abstract
MR imaging of fetal head and neck anomalies. View Abstract
Congenital abnormalities of the gastrointestinal tract. View Abstract
Calcified ureteral stricture in a child with polyarteritis nodosa. View Abstract
Intratesticular varicocele in adolescents: a reversible anechoic lesion of the testis. View Abstract
Fetal thoracic abnormalities: MR imaging. View Abstract
Correlation of contrast-enhanced power Doppler sonography and conventional angiography of abduction-induced hip ischemia in piglets. View Abstract
Ultrasonographic guidance for location of the trachea during the EXIT procedure for cervical teratoma. View Abstract
Pediatric spine ultrasound View Abstract
A comparison of MRI and laparoscopy in detecting pelvic structures in cases of vaginal agenesis. View Abstract
Ultrasound-guided fetal tracheal occlusion. View Abstract
Ultrasound of the Newborn Hip View Abstract
Definition of normal ultrasound and magnetic resonance imaging characteristics of fetal sheep development as a standard for in utero evaluation of models of congenital abnormality View Abstract
Ultrasound-guided fetal tracheal occlusion View Abstract
Progressive fetal bronchial obstruction caused by a bronchogenic cyst diagnosed using prenatal MR imaging. View Abstract
99m Technetium dimercapto-succinic acid renal scintigraphy abnormalities in infants with sterile high grade vesicoureteral reflux. View Abstract
Imaging of fetal thoracic abnormalities with ultrasound and magnetic resonance imaging View Abstract
Experimental fetal vesicoureteral reflux induces renal tubular and glomerular damage, and is associated with persistent bladder instability. View Abstract
Nonradiopaque penetrating foreign body: "a sticky situation". View Abstract
Depiction of renal perfusion defects with contrast-enhanced harmonic sonography in a porcine model. View Abstract
Renal blood flow in pigs: changes depicted with contrast-enhanced harmonic US imaging during acute urinary obstruction. View Abstract
Pediatric Musculoskeletal MR Techniques View Abstract
Renal findings on radiological followup of patients with Beckwith-Wiedemann syndrome. View Abstract
Techniques, coils, pulse sequences, and contrast enhancement in pediatric musculoskeletal MR imaging. View Abstract
Excitotoxin-induced cerebral hyperemia in newborn piglets: regional cerebral blood flow mapping with contrast-enhanced power Doppler US. View Abstract
Ossifying renal tumor of infancy presenting as a palpable abdominal mass. View Abstract
Neonatal pig brain: lack of heating during Doppler US. View Abstract
Renal cortical ischemia in rabbits revealed by contrast-enhanced power Doppler sonography. View Abstract
Imaging techniques to assess the pelvis in young females. View Abstract
Genitourinary tract View Abstract
Normal gadolinium-enhanced MR images of the developing appendicular skeleton: Part I. Cartilaginous epiphysis and physis. View Abstract
Normal gadolinium-enhanced MR images of the developing appendicular skeleton: Part 2. Epiphyseal and metaphyseal marrow. View Abstract
Radiologic-Pathologic Conference of Children's Hospital Boston: bilateral asymptomatic renal enlargement. View Abstract
Use of the mastoid fontanelle for improved sonographic visualization of the neonatal midbrain and posterior fossa. View Abstract
The sonographic diagnosis of infravesical obstruction in children: evaluation of bladder wall thickness indexed to bladder filling. View Abstract
Pediatric case of the day. Hepatorenal tyrosinemia (tyrosinemia type I). View Abstract
Potential role of Color Doppler sonograpy in defining the location of extracerebral fluid collections in infants View Abstract
Absence of a renal sinus echo complex in the ectopic kidney of a child: a normal finding. View Abstract
Serial imaging of the liver in patients with glycogen storage disease View Abstract
Computer-aided differential diagnosis in radiology - Hyperray View Abstract
Transendothelial transport of macromolecules in isolated perfused microvessels View Abstract