American Board of Psychiatry and Neurology (Child and Adolescent Neurology)
Professional History
I am a neurologist focusing on understanding neurological outcomes in congenital heart disease. Through my clinical care, I am uniquely situated to allow my patient experiences to inform our research. At the same time, I am able to provide families with information about the latest research advances in the field. By intertwining clinical care and research, I strive to bring a richer perspective to both research and to my patients and their families.
My clinical work is as a neurologist with the Cardiac Neurodevelopmental Neurology Program. Here I treat conditions such as developmental delay, motor concerns, attention deficit hyperactivity disorder (ADHD) and learning disabilities. I also see patients in the neurology consultation service.
My research lies at the intersection of neurology and cardiology, aiming to illuminate the neurobiological underpinnings of neurodevelopmental impairment in congenital heart disease.
Currently, I am the Principal Investigator of a fetal MRI study that investigates fetal brain measurements in congenital heart disease to determine whether in utero markers of abnormal brain development can be identified. The ultimate goal of the study is to establish neurobiological targets for fetal neuroprotective intervention and identify those patients most likely to benefit from such therapy.
Approach to Care
As the child of a clinical psychologist and scientist, I have always been interested in linking human experience with underlying biology. As part of the Cardiac Neurodevelopmental Program, I have the wonderful privilege of being able to work with children and their families over many years. The greatest joy of my practice is being able to support families as their infants grow into childhood and beyond.
My focus is to be a compassionate physician who is continually bringing the latest in clinical research on cardioneurology to the precious children entrusted to us.
Publications
Foetal cortical expansion is associated with neurodevelopmental outcome at 2-years in congenital heart disease: a longitudinal follow-up study. View Abstract
Graph-based prototype inverse-projection for identifying cortical sulcal pattern abnormalities in congenital heart disease. View Abstract
Noncoding variants and sulcal patterns in congenital heart disease: Machine learning to predict functional impact. View Abstract
Detailed delineation of the fetal brain in diffusion MRI via multi-task learning. View Abstract
Detailed delineation of the fetal brain in diffusion MRI via multi-task learning. View Abstract
Meta-regression of sulcal patterns, clinical and environmental factors on neurodevelopmental outcomes in participants with multiple CHD types. View Abstract
Divergent growth of the transient brain compartments in fetuses with nonsyndromic isolated clefts involving the primary and secondary palate. View Abstract
Risk factors for health impairments in children after hospitalization for acute COVID-19 or MIS-C. View Abstract
Atypical fetal brain development in fetuses with non-syndromic isolated musculoskeletal birth defects (niMSBDs). View Abstract
Factors Associated With Attendance for Cardiac Neurodevelopmental Evaluation. View Abstract
Neurological and Psychological Sequelae Associated With Multisystem Inflammatory Syndrome in Children. View Abstract
Abnormal prenatal brain development in Chiari II malformation. View Abstract
Abnormal development of transient fetal zones in mild isolated fetal ventriculomegaly. View Abstract
Learning to segment fetal brain tissue from noisy annotations. View Abstract
Fetal Brain Development in Congenital Heart Disease. View Abstract
Quantification of sulcal emergence timing and its variability in early fetal life: Hemispheric asymmetry and sex difference. View Abstract
Sleep Patterns in Young Children with Congenital Heart Disease. View Abstract
Maternal Social Risk, Gestational Age at Delivery, and Cognitive Outcomes among Adolescents Born Extremely Preterm. View Abstract
Neurodevelopmental and Mental Health Outcomes in Patients With Fontan Circulation: A State-of-the-Art Review. View Abstract
Neurological features in infants with congenital heart disease. View Abstract
Optimal Method for Fetal Brain Age Prediction Using Multiplanar Slices From Structural Magnetic Resonance Imaging. View Abstract
Abnormal Right-Hemispheric Sulcal Patterns Correlate with Executive Function in Adolescents with Tetralogy of Fallot. View Abstract
Association between Quantitative MR Markers of Cortical Evolving Organization and Gene Expression during Human Prenatal Brain Development. View Abstract
A Deep Attentive Convolutional Neural Network for Automatic Cortical Plate Segmentation in Fetal MRI. View Abstract
Tractography of the Cerebellar Peduncles in Second- and Third-Trimester Fetuses. View Abstract
Fetal Cortical Plate Segmentation Using Fully Convolutional Networks With Multiple Plane Aggregation. View Abstract
Regional Brain Growth Trajectories in Fetuses with Congenital Heart Disease. View Abstract
Neurodevelopmental evaluation for school-age children with congenital heart disease: recommendations from the cardiac neurodevelopmental outcome collaborative. View Abstract
Neurodevelopmental evaluation strategies for children with congenital heart disease aged birth through 5 years: recommendations from the cardiac neurodevelopmental outcome collaborative. View Abstract
Association of Isolated Congenital Heart Disease with Fetal Brain Maturation. View Abstract
Spatiotemporal Differences in the Regional Cortical Plate and Subplate Volume Growth during Fetal Development. View Abstract
Temporal Patterns of Emergence and Spatial Distribution of Sulcal Pits During Fetal Life. View Abstract
In vivo characterization of emerging white matter microstructure in the fetal brain in the third trimester. View Abstract
Quantitative In vivo MRI Assessment of Structural Asymmetries and Sexual Dimorphism of Transient Fetal Compartments in the Human Brain. View Abstract
Early-Emerging Sulcal Patterns Are Atypical in Fetuses with Congenital Heart Disease. View Abstract
Correction of d-Transposition of the Great Arteries Sooner Rather Than Later. View Abstract
Early Neurodevelopmental Outcomes in Children Supported with ECMO for Cardiac Indications. View Abstract
Ascending Aorta Size at Birth Predicts White Matter Microstructure in Adolescents Who Underwent Fontan Palliation. View Abstract
Automatic labeling of cortical sulci for the human fetal brain based on spatio-temporal information of gyrification. View Abstract
Tract-Specific Group Analysis in Fetal Cohorts Using in utero Diffusion Tensor Imaging. View Abstract
Disorganized Patterns of Sulcal Position in Fetal Brains with Agenesis of Corpus Callosum. View Abstract
Fetal brain growth portrayed by a spatiotemporal diffusion tensor MRI atlas computed from in utero images. View Abstract
Genetic contribution to neurodevelopmental outcomes in congenital heart disease: are some patients predetermined to have developmental delay? View Abstract
Quantitative Folding Pattern Analysis of Early Primary Sulci in Human Fetuses with Brain Abnormalities. View Abstract
Temporal slice registration and robust diffusion-tensor reconstruction for improved fetal brain structural connectivity analysis. View Abstract
A normative spatiotemporal MRI atlas of the fetal brain for automatic segmentation and analysis of early brain growth. View Abstract
White Matter Volume Predicts Language Development in Congenital Heart Disease. View Abstract
A mixed bag: Differential influences of oxygenation and perfusion on brain development in congenital heart disease. View Abstract