Barbara O'Brien, MD
Faculty, Fetal Care and Surgery Center
Associate Professor of Obstetrics, Gynecology and Reproductive Biology, Harvard Medical School
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Barbara O'Brien, MD
Faculty, Fetal Care and Surgery Center
Associate Professor of Obstetrics, Gynecology and Reproductive Biology, Harvard Medical School
Medical Services
Languages
English
Education
Medical School
New York Medical College
Valhalla
NY
Internship
Obstetrics and Gynecology
Tufts Medical Center
Boston
MA
Residency
Obstetrics and Gynecology
Tufts Medical Center
Boston
MA
Fellowship
Maternal-Fetal Medicine/Medical Genomics
Tufts Medical Center
Boston
MA
Professional History
Dr. O’Brien is a maternal-fetal medicine specialist at Beth Israel Deaconess Medical Center (BIDMC). She is triple-board certified in Obstetrics and Gynecology, Maternal-Fetal Medicine, as well as Medical Genetics and Genomics, and is an Associate Professor at Harvard Medical School. She completed her residency and fellowship trainings at Tufts Medical Center. Her clinical interests include medical complications of pregnancy, non-invasive prenatal genetic testing and prenatal diagnosis. She also serves as the Program Director of the Maternal-Fetal Medicine Fellowship and the newly combined Maternal-Fetal Medicine/Genetics and Genomics Fellowship at BIDMC and Boston Children’s Hospital. In addition to her faculty position at BIDMC, she works in collaboration with the Fetal Care and Surgery Center at Boston Children's Hospital to provide consultations to patients with complex fetal conditions.
Publications
Caudal regression in fetus with de novo SMARCA2 pathogenic variant. View Abstract
Prenatal Screening and Diagnosis: Time for a Paradigm Shift. View Abstract
RASopathies are the most common set of monogenic syndromes identified by exome sequencing for nonimmune hydrops fetalis: A systematic review and meta-analysis. View Abstract
Cochrane update: news and reviews from the Cochrane US Network. View Abstract
Clinician communication after discovery of a soft marker of aneuploidy during pregnancy: A mixed methods assessment of a communication workshop. View Abstract
Low fetal fraction of cell-free DNA predicts placental dysfunction and hypertensive disease in pregnancy. View Abstract
Risk of ischemic placental disease in fresh and frozen embryo transfer cycles. View Abstract
What education, background, and credentials are required to provide genetic counseling? View Abstract
Peripartum management of HLA alloimmune platelet refractoriness. View Abstract
Cell-Free DNA: Screening for Single-Gene Disorders and Determination of Fetal Rhesus D Genotype. View Abstract
Relaxin-2 connecting peptide (pro-RLX2) levels in second trimester serum samples to predict preeclampsia. View Abstract
Separate transcriptionally regulated pathways specify distinct classes of sister dendrites in a nociceptive neuron. View Abstract
How Should Clinicians Counsel a Woman with a Strong Family History of Early-Onset Alzheimer's Disease about Her Pregnancy? View Abstract
Nuchal translucency measurement in the era of prenatal screening for aneuploidy using cell free (cf)DNA. View Abstract
The clinical utility of DNA-based screening for fetal aneuploidy by primary obstetrical care providers in the general pregnancy population. View Abstract
Neurodevelopment: Three's a Crowd, Four Is a Receptor Complex. View Abstract
The North American Fetal Therapy Network Consensus Statement: prenatal management of uncomplicated monochorionic gestations. View Abstract
Managing Multi-Center Recruitment in the PLCO Cancer Screening Trial. View Abstract
Comprehensive Quality Management (CQM) in the PLCO Trial. View Abstract
The North American Fetal Therapy Network consensus statement: prenatal surveillance of uncomplicated monochorionic gestations. View Abstract
Iatrogenic Preterm Premature Rupture of Membranes after Fetoscopic Laser Ablative Surgery. View Abstract
Evaluation of patient education materials: the example of circulating cell free DNA testing for aneuploidy. View Abstract
Maternal plasma DNA testing: experience of women counseled at a prenatal diagnosis center. View Abstract
In reply. View Abstract
Fetal craniopharyngioma: management, postmortem diagnosis, and literature review of an intracranial tumor detected in utero. View Abstract
Maternal and fetal safety of fluid-restrictive general anesthesia for endoscopic fetal surgery in monochorionic twin gestations. View Abstract
Noninvasive prenatal testing for microdeletion syndromes and expanded trisomies: proceed with caution. View Abstract
Monochorionic twins discordant for mosaic trisomy 14. View Abstract
Maternal plasma DNA testing for aneuploidy in pregnancies achieved by assisted reproductive technologies. View Abstract
Karyotype versus microarray testing for genetic abnormalities after stillbirth. View Abstract
Midwifery and obstetrics: twenty years of collaborative academic practice. View Abstract
Colorectal-cancer incidence and mortality with screening flexible sigmoidoscopy. View Abstract
Long-term morbidity after fetal endoscopic surgery for severe twin-to-twin transfusion syndrome. View Abstract
Laser ablation of placental vessels in twin-to-twin transfusion syndrome: a paradigm for endoscopic fetal surgery. View Abstract
Linking topography to tonotopy in the mouse auditory thalamocortical circuit. View Abstract
Bombay blood type and use of red cell apheresis during pregnancy. View Abstract
Improving foodborne illness prevention among transplant recipients. View Abstract
Influence of experience, case load, and stage distribution on outcome of endoscopic laser surgery for TTTS--a review. View Abstract
Feto-fetal transfusion syndrome in monochorionic quadruplets. View Abstract
Reflectance spectrometry for real-time hemoglobin determination of placental vessels during endoscopic laser surgery for twin-to-twin transfusion syndrome. View Abstract
The pediatric surgeons' contribution to in utero treatment of twin-to-twin transfusion syndrome. View Abstract
Prenatal features of Costello syndrome: ultrasonographic findings and atrial tachycardia. View Abstract
MFM/geneticist view on prenatal management of twins. View Abstract
Mortality results from a randomized prostate-cancer screening trial. View Abstract
Uses of misoprostol in obstetrics and gynecology. View Abstract
Power and interpretation of a randomized study on the treatment of severe twin-to-twin transfusion syndrome. View Abstract
Sampling the sample. View Abstract
Cell-free fetal DNA in amniotic fluid: unique fragmentation signatures in euploid and aneuploid fetuses. View Abstract
Postpartum haemorrhage: prevention. View Abstract
Fetal therapy for single gene disorders. View Abstract
Survival factors in replantation and revascularization of the amputated thumb--10 years experience. View Abstract
Replantation and revascularization of digits. View Abstract
Results of the use of autotransplantation of the intraabdominal testis using microsurgical vascular anastomosis. View Abstract
An experimental study of microvascular patency using a continuous suture technique. View Abstract
The cross toe flap. View Abstract
Coexisting familial abnormalities of karyotype and phenotype. Chromosome 16 and an unusual form of cutis laxa with skin webs. View Abstract
Locations