April Levin, MD
Neurologist, Department of Neurology
Assistant Professor of Neurology, Harvard Medical School
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April Levin, MD
Neurologist, Department of Neurology
Assistant Professor of Neurology, Harvard Medical School
Medical Services
Languages
English
Education
Undergraduate School
Brown University
2003
Providence
RI
Medical School
Yale University School of Medicine
2007
New Haven
CT
Residency
Boston Combined Residency Program (BCRP)
2009
Boston
MA
Residency
Neurology
Boston Children's Hospital
2012
Boston
MA
Fellowship
Behavioral Neurology
Boston Children's Hospital
2014
Boston
MA
Fellowship
Postdoctoral Research
Boston Children's Hospital
2014
Boston
MA
Certifications
American Board of Psychiatry and Neurology (Child and Adolescent Neurology)
Professional History
I am currently an instructor and attending physician in neurology. My clinical work and research focus on management of autism from a child neurology perspective.
In the neurology clinic, my focus is on caring for children with autism. In addition to seeing patients, I am working to implement an online parent questionnaire that will help families and clinicians monitor outcomes over time in children with autism.
My primary research focuses on identifying biomarkers of autism, using information about brain rhythms as measured by EEG. The long-term goal of this research is to find new ways to predict, diagnose, and monitor autism; in the process, I hope to shed light on how the brain works in children with autism.
I am also involved with the Bucharest Early Intervention Project, which examines the effects of institutionalization versus foster care on child development. Alongside my participation in this research project, I have been involved in clinical, teaching, and volunteer work in Romanian hospitals and orphanages since 1999.
In summary, my interests remain focused on evaluating and treating autism and related neurodevelopmental disorders, from a neurological perspective.
Approach to Care
Taking care of patients and their families is my most important job. Children and families facing autism often have a lot of questions. They need to know about therapies, education, and medical problems that sometimes go along with autism. They need to know about coping with their child’s diagnosis and building a supportive community. There’s still a lot that is unknown about autism, however, which means that families often come to my office with questions that don’t have an answer yet. That’s why I do research. I want to find answers to those unanswered questions.
Publications
Longitudinal relationships between social anhedonia and internalizing symptoms in autistic children: results from the Autism Biomarkers Consortium for Clinical Trials. View Abstract
Associations Among EEG Aperiodic Slope, Infant Temperament, and Maternal Anxiety/Depression Symptoms in Infancy. View Abstract
A roadmap for SHANK3-related Epilepsy Research: recommendations from the 2023 strategic planning workshop. View Abstract
Early differential impact of MeCP2 mutations on functional networks in Rett syndrome patient-derived human cerebral organoids. View Abstract
Parsing evoked and induced gamma response differences in Autism: A visual evoked potential study. View Abstract
Modeling intra-individual inter-trial EEG response variability in autism. View Abstract
Constrained Multivariate Functional Principal Components Analysis for Novel Outcomes in Eye-Tracking Experiments. View Abstract
Clinically derived 12-factor structure and confirmatory factor analysis of the neurodevelopmental parent report for outcome monitoring. View Abstract
Evaluation of clinical assessments of social abilities for use in autism clinical trials by the autism biomarkers consortium for clinical trials. View Abstract
A circuit-level biomarker of Rett syndrome based on ectopic phase-amplitude coupling during slow-wave-sleep. View Abstract
Associations Between Infant Screen Use, Electroencephalography Markers, and Cognitive Outcomes. View Abstract
The role of aperiodic spectral slope in event-related potentials and cognition among children with and without attention deficit hyperactivity disorder. View Abstract
A randomized controlled trial of everolimus for neurocognitive symptoms in PTEN hamartoma tumor syndrome. View Abstract
Concomitant medication use in children with autism spectrum disorder: Data from the Autism Biomarkers Consortium for Clinical Trials. View Abstract
A functional model for studying common trends across trial time in eye tracking experiments. View Abstract
The Autism Biomarkers Consortium for Clinical Trials: Initial Evaluation of a Battery of Candidate EEG Biomarkers. View Abstract
Absence of dynamic neural oscillatory response to environmental conditions marks childhood attention deficit hyperactivity disorder. View Abstract
Multilevel hybrid principal components analysis for region-referenced functional electroencephalography data. View Abstract
Identifying Age Based Maturation in the ERP Response to Faces in Children With Autism: Implications for Developing Biomarkers for Use in Clinical Trials. View Abstract
The autism biomarkers consortium for clinical trials: evaluation of a battery of candidate eye-tracking biomarkers for use in autism clinical trials. View Abstract
Bridges Through the Cloud: Towards Clinical Biomarkers of Cognitive Neurophysiology. View Abstract
Neurobehavioral Biomarkers: An EEG Family Reunion. View Abstract
Parental Language Input Predicts Neuroscillatory Patterns Associated with Language Development in Toddlers at Risk of Autism. View Abstract
EEG Phase-Amplitude Coupling Strength and Phase Preference: Association with Age over the First Three Years after Birth. View Abstract
Shifted phase of EEG cross-frequency coupling in individuals with Phelan-McDermid syndrome. View Abstract
Autism Spectrum Disorder Parent Report for Outcome Monitoring: A Preliminary Report of Development and Clinical Utility. View Abstract
EEG-IP: an international infant EEG data integration platform for the study of risk and resilience in autism and related conditions. View Abstract
Day-to-Day Test-Retest Reliability of EEG Profiles in Children With Autism Spectrum Disorder and Typical Development. View Abstract
The Autism Biomarkers Consortium for Clinical Trials (ABC-CT): Scientific Context, Study Design, and Progress Toward Biomarker Qualification. View Abstract
Use of longitudinal EEG measures in estimating language development in infants with and without familial risk for autism spectrum disorder. View Abstract
Biomarker Acquisition and Quality Control for Multisite Studies: The Autism Biomarkers Consortium for Clinical Trials View Abstract
Biomarker Acquisition and Quality Control for Multi-Site Studies: The Autism Biomarkers Consortium for Clinical Trials. View Abstract
Longitudinal EEG power in the first postnatal year differentiates autism outcomes. View Abstract
Electroencephalographic spectral power as a marker of cortical function and disease severity in girls with Rett syndrome. View Abstract
Reduced frontal gamma power at 24 months is associated with better expressive language in toddlers at risk for autism. View Abstract
Early motor abilities in infants at heightened versus low risk for ASD: A Baby Siblings Research Consortium (BSRC) study. View Abstract
Discovering translational biomarkers in neurodevelopmental disorders. View Abstract
BEAPP: The Batch Electroencephalography Automated Processing Platform. View Abstract
The Harvard Automated Processing Pipeline for Electroencephalography (HAPPE): Standardized Processing Software for Developmental and High-Artifact Data. View Abstract
EEG power at 3 months in infants at high familial risk for autism. View Abstract
Inhibition-Based Biomarkers for Autism Spectrum Disorder. View Abstract
Autism associated with early institutionalization, high intelligence, and naturalistic behavior therapy in a 7-year-old boy. View Abstract
Social communication difficulties and autism in previously institutionalized children. View Abstract
Motor outcomes in children exposed to early psychosocial deprivation. View Abstract
Clinical use of ictal SPECT in secondarily generalized tonic-clonic seizures. View Abstract
Cortical and subcortical networks in human secondarily generalized tonic-clonic seizures. View Abstract
Early treatment suppresses the development of spike-wave epilepsy in a rat model. View Abstract
Shedding of tumor necrosis factor type 1 receptor after experimental spinal cord injury. View Abstract
msJAMA. Genomics in medicine and public health: role of cost-effectiveness analysis. View Abstract
Locations