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Ralph Salloum, MD
Attending, Dana-Farber/Boston Children's Cancer and Blood Disorders Center
Associate Professor of Pediatrics, Harvard Medical School
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Ralph Salloum, MD
Attending, Dana-Farber/Boston Children's Cancer and Blood Disorders Center
Associate Professor of Pediatrics, Harvard Medical School
Medical Services
Languages
Arabic
English
French
Spanish
Education
Medical School
American University of Beirut
2006
Beirut
Lebanon
Residency
Internal Medicine/Pediatrics
Wayne State University/ Children's Hospital of Michigan
2011
Detroit
MI
Fellowship
Pediatric Hematology/Oncology Cincinnati
Cincinnati Children's Hospital Medical Center
2014
Cincinnati
OH
Fellowship
Pediatric Neuro-Oncology
Cincinnati Children's Hospital Medical Center
2015
Cincinnati
OH
Certifications
American Board of Internal Medicine (General)
American Board of Pediatrics (General)
American Board of Pediatrics (Hematology-Oncology)
Professional History
Dr. Salloum earned his medical degree from the American University of Beirut. He completed a combined residency training in internal medicine and pediatrics at Wayne State University/Children’s Hospital of Michigan. He did his fellowship training in pediatric hematology/oncology and pediatric neuro-oncology at Cincinnati Children’s Hospital Medical Center. He conducts research in both translational and clinical aspects of pediatric neuro-oncology with a focus on developmental therapeutics and brain tumor survivorship.
Publications
TissUnet: Improved extracranial tissue and cranium segmentation for children through adulthood. View Abstract
Salvage therapies for first relapse of SHH medulloblastoma in early childhood. View Abstract
MRD4U: A path to development for personalized liquid biopsy for children with central nervous system tumors. View Abstract
Radiomic-based prognostic score for survival risk-stratification in pediatric medulloblastoma tumors: A multi-institutional study. View Abstract
Neurocognitive outcomes and functional independence in adult survivors of childhood medulloblastoma diagnosed over 3 decades. View Abstract
Molecular characterization of gliomas and glioneuronal tumors amid Noonan syndrome: cancer predisposition examined. View Abstract
nnU-Net-based Segmentation of Tumor Subcompartments in Pediatric Medulloblastoma Using Multiparametric MRI: A Multi-institutional Study. View Abstract
Evolving therapies, neurocognitive outcomes, and functional independence in adult survivors of childhood glioma. View Abstract
Caregivers matter: Neurological vulnerability for pediatric brain tumor survivors. View Abstract
Outcomes of Infants and Young Children With Relapsed Medulloblastoma After Initial Craniospinal Irradiation-Sparing Approaches: An International Cohort Study. View Abstract
Novel MRI deformation-heterogeneity radiomic features are associated with molecular subgroups and overall survival in pediatric medulloblastoma: Preliminary findings from a multi-institutional study. View Abstract
Immunohistochemical assessment and clinical, histopathologic, and molecular correlates of membranous somatostatin type-2A receptor expression in high-risk pediatric central nervous system tumors. View Abstract
Risk of secondary malignant neoplasms in children following proton therapy vs. photon therapy for primary CNS tumors: A systematic review and meta-analysis. View Abstract
An unusual case of atypical teratoid/rhabdoid tumor, initially diagnosed as atypical pituitary adenoma in a 13-year-old male patient. View Abstract
Medulloblastoma in the Modern Era: Review of Contemporary Trials, Molecular Advances, and Updates in Management. View Abstract
Molecular Heterogeneity in Pediatric Malignant Rhabdoid Tumors in Patients With Multi-Organ Involvement. View Abstract
Comorbidity Burden in a Cohort of Adolescent and Young Adult Patients Diagnosed with Central Nervous System Tumors and Sarcomas. View Abstract
Phase I study of ribociclib and everolimus in children with newly diagnosed DIPG and high-grade glioma: A CONNECT pediatric neuro-oncology consortium report. View Abstract
Impact of COVID-19 on adolescent and emerging adult brain tumor survivors and their parents. View Abstract
Trametinib-associated Hyponatremia in a Child With Low-grade Glioma is Not Seen Following Treatment With Alternative MEK Inhibitor. View Abstract
A Mixed-Methods Analysis of Family Perceptions of Neuropsychological Evaluation and Resources for Pediatric Brain Tumor Survivors. View Abstract
Echocardiographic myocardial strain analysis describes subclinical cardiac dysfunction after craniospinal irradiation in pediatric and young adult patients with central nervous system tumors. View Abstract
Overcoming barriers to establishing autopsy procurement programs in pediatric patients with central nervous system tumors: a call to develop regional centers. View Abstract
Characterizing temporal genomic heterogeneity in pediatric low-grade gliomas. View Abstract
Active and Protected: Developing a "Safer Sex" Handout for Adolescents and Young Adults with Cancer. View Abstract
A phase I/II study of ribociclib following radiation therapy in children with newly diagnosed diffuse intrinsic pontine glioma (DIPG). View Abstract
LC-MS/MS method for quantitation of the CK2 inhibitor silmitasertib (CX-4945) in human plasma, CSF, and brain tissue, and application to a clinical pharmacokinetic study in children with brain tumors. View Abstract
A Survivor's Journey: Preliminary efficacy of an online problem-solving therapy for survivors of pediatric brain tumor. View Abstract
Late Morbidity and Mortality Among Medulloblastoma Survivors Diagnosed Across Three Decades: A Report From the Childhood Cancer Survivor Study. View Abstract
Malignant peripheral nerve sheath tumor: Transformation in a patient with neurofibromatosis type 2. View Abstract
Development of a Web-Based Psychosocial Intervention for Adolescent and Young Adult Survivors of Pediatric Brain Tumor. View Abstract
Characterizing temporal genomic heterogeneity in pediatric high-grade gliomas. View Abstract
Blood-brain barrier-adapted precision medicine therapy for pediatric brain tumors. View Abstract
A molecular biology and phase II study of imetelstat (GRN163L) in children with recurrent or refractory central nervous system malignancies: a pediatric brain tumor consortium study. View Abstract
Response of Blue Rubber Bleb Nevus Syndrome to Sirolimus Treatment. View Abstract
The G protein Gas acts as a tumor suppressor in sonic hedgehog signaling-driven tumorigenesis. View Abstract
A pilot study of bevacizumab-based therapy in patients with newly diagnosed high-grade gliomas and diffuse intrinsic pontine gliomas. View Abstract