• English


Undergraduate Degree

Electrical and Computer Engineering
  • University of California, San Diego , La Jolla , CA

Graduate Degree

  • Massachusetts Institute of Technology , Cambridge , MA

Graduate Degree

  • Massachusetts Institute of Technology , Cambridge , MA

Medical School

  • Harvard Medical School , Boston , MA


  • Massachusetts General Hospital , Boston , MA


  • Brigham and Women's Hospital , Boston , MA


Pediatric Radiology
  • Boston Children's Hospital , Boston , MA


  • American Board of Radiology, Diagnostic Radiology
  • American Board of Radiology, Pediatric Radiology


Publications powered by Harvard Catalyst Profiles

  1. Tsai A, Perez-Rossello J, Connolly SA, Kawai K, Kleinman PK. Temporal Pattern of Radiographic Findings of Costochondral Junction Rib Fractures on Serial Skeletal Surveys in Suspected Infant Abuse. AJR Am J Roentgenol. 2020 08 26. View abstract
  2. Tsai A, Johnston PR, Gordon LB, Walters M, Kleinman M, Laor T. Skeletal maturation and long-bone growth patterns of patients with progeria: a retrospective study. Lancet Child Adolesc Health. 2020 04; 4(4):281-289. View abstract
  3. Tsai A, Connolly SA, Ecklund K, Johnston PR, Kleinman PK. Subperiosteal new bone formation with the distal tibial classic metaphyseal lesion: prevalence on radiographic skeletal surveys. Pediatr Radiol. 2019 04; 49(4):551-558. View abstract
  4. Tsai A, Kleinman PK, Laor T, Kasser JR. Lower-extremity growth patterns and skeletal maturation in children with unilateral fibular hemimelia. Pediatr Radiol. 2019 01; 49(1):122-127. View abstract
  5. Tsai A, Laor T, Estroff JA, Kasser JR. Constant inhibition in congenital lower extremity shortening: does it begin in utero? Pediatr Radiol. 2018 09; 48(10):1451-1462. View abstract
  6. Tsai A, Johnston PR, Perez-Rossello JM, Breen MA, Kleinman PK. The distal tibial classic metaphyseal lesion: medial versus lateral cortical injury. Pediatr Radiol. 2018 07; 48(7):973-978. View abstract
  7. Tsai A, Coats B, Kleinman PK. Biomechanics of the classic metaphyseal lesion: finite element analysis. Pediatr Radiol. 2017 Nov; 47(12):1622-1630. View abstract
  8. Tsai A, Barnewolt CE, Prabhu SP, Yonekura R, Hosmer A, Schulz NE, Weinstock PH. Erratum to "Creation and Validation of a Simulator for Neonatal Brain Ultrasonography: A Pilot Study": [Acad Radiol 2017; 24:76-83]. Acad Radiol. 2018 05; 25(5):684. View abstract
  9. Tsai A, Barnewolt CE, Prabhu SP, Yonekura R, Hosmer A, Schulz NE, Weinstock PH. Creation and Validation of a Simulator for Neonatal Brain Ultrasonography: A Pilot Study. Acad Radiol. 2017 01; 24(1):76-83. View abstract
  10. Tsai A, Stamoulis C, Barber I, Kleinman PK. Infant lower extremity long bone growth rates: comparison of contemporary with early 20th century data using mixed effect models. Am J Hum Biol. 2017 Jan; 29(1). View abstract
  11. Breen MA, Tsai A, Stamm A, Kleinman PK. Bone age assessment practices in infants and older children among Society for Pediatric Radiology members. Pediatr Radiol. 2016 Aug; 46(9):1269-74. View abstract
  12. Zapala MA, Tsai A, Kleinman PK. Growth recovery lines are more common in infants at high vs. low risk for abuse. Pediatr Radiol. 2016 Aug; 46(9):1275-81. View abstract
  13. Tsai A, Stamoulis C, Bixby SD, Breen MA, Connolly SA, Kleinman PK. Infant bone age estimation based on fibular shaft length: model development and clinical validation. Pediatr Radiol. 2016 Mar; 46(3):342-56. View abstract
  14. Lessenich EM, Kimia AA, Mandeville K, Li J, Landschaft A, Tsai A, Bachur RG. The Frequency of Postreduction Interventions After Successful Enema Reduction of Intussusception. Acad Emerg Med. 2015 Sep; 22(9):1042-7. View abstract
  15. Perez-Rossello JM, McDonald AG, Rosenberg AE, Tsai A, Kleinman PK. Absence of rickets in infants with fatal abusive head trauma and classic metaphyseal lesions. Radiology. 2015 Jun; 275(3):810-21. View abstract
  16. Callahan MJ, Kleinman PL, Strauss KJ, Bandos A, Taylor GA, Tsai A, Kleinman PK. Pediatric CT dose reduction for suspected appendicitis: a practice quality improvement project using artificial Gaussian noise--part 1, computer simulations. AJR Am J Roentgenol. 2015 Jan; 204(1):W86-94. View abstract
  17. Tsai A, McDonald AG, Rosenberg AE, Gupta R, Kleinman PK. Erratum to: High-resolution CT with histopathological correlates of the classic metaphyseal lesion of infant abuse. Pediatr Radiol. 2014 Sep; 44(9):1190. View abstract
  18. Tsai A, McDonald AG, Rosenberg AE, Gupta R, Kleinman PK. Reply to Dr. Oestreich's letter regarding the metaphyseal collar. Pediatr Radiol. 2014 Aug; 44(8):1048. View abstract
  19. Tsai A, McDonald AG, Rosenberg AE, Gupta R, Kleinman PK. High-resolution CT with histopathological correlates of the classic metaphyseal lesion of infant abuse. Pediatr Radiol. 2014 Feb; 44(2):124-40. View abstract
  20. Tsai A, McDonald AG, Rosenberg AE, Stamoulis C, Kleinman PK. Discordant radiologic and histological dimensions of the zone of provisional calcification in fetal piglets. Pediatr Radiol. 2013 Dec; 43(12):1606-14. View abstract
  21. Tsai A, Connolly S, Nedder A, Shapiro F. Visualization and analysis of the deforming piglet femur and hip following experimentally induced avascular necrosis of the femoral head. IEEE Trans Biomed Eng. 2013 Jun; 60(6):1742-50. View abstract
  22. Tsai A, Coats B, Kleinman PK. Stress profile of infant rib in the setting of child abuse: A finite element parametric study. J Biomech. 2012 Jul 26; 45(11):1861-8. View abstract
  23. Tsai A, Chaudry G, Spencer S, Kasser JR, Alomari AI. Misdiagnosis of knee venous malformation as juvenile idiopathic arthritis. J Pediatr Orthop. 2011 Sep; 31(6):683-90. View abstract
  24. Tsai A, Caprioli J, Shen LQ. Coupled parametric model for estimation of visual field tests based on OCT macular thickness maps, and vice versa, in glaucoma care. Med Image Anal. 2012 Jan; 16(1):101-13. View abstract
  25. Tsai A, Paltiel HJ, Sena LM, Kim HB, Fishman SJ, Alomari AI. Neonatal hemochromatosis and patent ductus venosus: clinical course and diagnostic pitfalls. Pediatr Radiol. 2009 Aug; 39(8):823-7. View abstract
  26. Tsai A, Wells WM, Warfield SK, Willsky AS. An EM algorithm for shape classification based on level sets. Med Image Anal. 2005 Oct; 9(5):491-502. View abstract
  27. Tsai A, Rhea JT, Novelline RA. The jet ski open-book pelvic fracture: diagnosis with multidetector CT. Emerg Radiol. 2003 Oct; 10(2):96-8. View abstract
  28. Tsai A, Yezzi A, Wells W, Tempany C, Tucker D, Fan A, Grimson WE, Willsky A. A shape-based approach to the segmentation of medical imagery using level sets. IEEE Trans Med Imaging. 2003 Feb; 22(2):137-54. View abstract
  29. Maeda T, Tsai AY, Saito H. Mutations in a protein tyrosine phosphatase gene (PTP2) and a protein serine/threonine phosphatase gene (PTC1) cause a synthetic growth defect in Saccharomyces cerevisiae. Mol Cell Biol. 1993 Sep; 13(9):5408-17. View abstract
  30. Saito H, Streuli M, Krueger NX, Itoh M, Tsai AY. CD45 and a family of receptor-linked protein tyrosine phosphatases. Biochem Soc Trans. 1992 Feb; 20(1):165-9. View abstract
  31. Tsai AY, Itoh M, Streuli M, Thai T, Saito H. Isolation and characterization of temperature-sensitive and thermostable mutants of the human receptor-like protein tyrosine phosphatase LAR. J Biol Chem. 1991 Jun 05; 266(16):10534-43. View abstract
  32. Streuli M, Krueger NX, Tsai AY, Saito H. A family of receptor-linked protein tyrosine phosphatases in humans and Drosophila. Proc Natl Acad Sci U S A. 1989 Nov; 86(22):8698-702. View abstract
  33. Tsai AY, Streuli M, Saito H. Integrity of the exon 6 sequence is essential for tissue-specific alternative splicing of human leukocyte common antigen pre-mRNA. Mol Cell Biol. 1989 Oct; 9(10):4550-5. View abstract