EDUCATION

Undergraduate Degree

  • Columbia Union College , 1992 , Takoma Park , MD

Medical School

  • Loma Linda University , 1996 , Loma Linda , CA

Internship

  • Medical College of Ohio , 1997 , Toledo , OH

Residency

  • Medical College of Ohio , 2000 , Toledo , OH

Fellowship

  • Baystate Medical Center, Tufts University of Medicine , 2003 , Boston , MA

Fellowship

  • Boston Children's Hospital/Brigham & Women's Hospital , 2004 , Boston , MA

Philosophy of Care

Dr. Michael Singh is originally from Takoma Park, Maryland and first came to Boston for his fellowships at Boston Children’s and Brigham and Women’s Hospital in 2003. He is acutely aware of the unique challenges patients with congenital heart disease and cardiovascular genetic conditions face as they age out of pediatric care, and has dedicated his cardiology practice to this population. Dr. Singh is committed to providing top-quality, lifelong care to his patients, who range from teenagers to adults in their golden years. Dr. Singh’s particular interests include aortopathies and aortic health in Marfan Syndrome and related connective tissue disorders, congenital heart conditions such as tetralogy of Fallot, coarctation of the aorta, single ventricle/Fontan and bicuspid aortic valve, and caring for patients with congenital heart disease and connective tissue disorder through pregnancy.

PROFESSIONAL HISTORY

Dr. Singh completed his M.D. at Loma Linda University Medical Center in California; Internal Medicine/Pediatric residency at the Medical College of Ohio; Adult Cardiovascular Disease fellowship at Baystate Medical Center-Tufts University of Medicine in Massachusetts; and Marfan Syndrome/Connective Tissue Disorder and Adult Congenital Heart Disease fellowships at Boston Children's Hospital and Brigham & Women’s Hospital. In addition to being co-director of the Adult Marfan Sydrome/Related Connective Tissue Disorder and Aortic Disease program of the Cardiovascular Genetics Service, he is also the inpatient director of the Boston Adult Congenital Heart (BACH)/Pulmonary Hypertension service. He is a staff cardiologist at the Brigham & Women’s Hospital and Boston Children's Hospital. His clinical efforts have centered on supporting existing programs in congenital heart disease, pulmonary hypertension, and pregnancy in congenital heart disease, currently spanning Brigham & Women’s Hospital and Boston Children’s Hospital, as well as, the establishment of regional center of excellence for adolescents and adults with Marfan syndrome and related connective tissue disorders at both Brigham & Women’s Hospital and Boston Children's Hospital. His research interests include aortic health, and database direction and development of outcomes assessment tools.

CERTIFICATIONS

  • American Board of Pediatrics, General Pediatrics
  • American Board of Internal Medicine
  • American Board of Internal Medicine, Adult Congenital Heart Disease
  • American Board of Internal Medicine, Cardiovascular Disease

PUBLICATIONS

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  1. Effect of Losartan or Atenolol on Children and Young Adults With Bicuspid Aortic Valve and Dilated Aorta. Am J Cardiol. 2021 04 01; 144:111-117. View abstract
  2. Surgical management of pediatric renovascular hypertension and midaortic syndrome at a single-center multidisciplinary program. J Vasc Surg. 2021 07; 74(1):79-89.e2. View abstract
  3. Intraperitoneal corticosteroids for recurrent ascites in patients with Fontan circulation: Initial clinical experience. J Card Surg. 2021 Feb; 36(2):735-738. View abstract
  4. Prevalence and Prognostic Association of a Clinical Diagnosis of Depression in Adult Congenital Heart Disease: Results of the Boston Adult Congenital Heart Disease Biobank. J Am Heart Assoc. 2020 05 05; 9(9):e014820. View abstract
  5. Planned vaginal delivery and cardiovascular morbidity in pregnant women with heart disease. Am J Obstet Gynecol. 2020 01; 222(1):77.e1-77.e11. View abstract
  6. Creatinine versus cystatin C to estimate glomerular filtration rate in adults with congenital heart disease: Results of the Boston Adult Congenital Heart Disease Biobank. Am Heart J. 2019 08; 214:142-155. View abstract
  7. Early and Midterm Outcomes of Valve-Sparing Aortic Root Replacement-Reimplantation Technique. Aorta (Stamford). 2018 Oct; 6(5):113-117. View abstract
  8. Transcatheter Aortic Valve Replacement for Bioprosthetic Aortic Stenosis in Pregnancy. JACC Cardiovasc Interv. 2018 10 08; 11(19):e161-e162. View abstract
  9. Relationship of Red Cell Distribution Width to Adverse Outcomes in Adults With Congenital Heart Disease (from the Boston Adult Congenital Heart Biobank). Am J Cardiol. 2018 11 01; 122(9):1557-1564. View abstract
  10. Whole Exome Sequencing Reveals a Monogenic Cause of Disease in ˜43% of 35 Families With Midaortic Syndrome. Hypertension. 2018 04; 71(4):691-699. View abstract
  11. Three-generation family with novel contiguous gene deletion on chromosome 2p22 associated with thoracic aortic aneurysm syndrome. . 2018 03; 176(3):560-569. View abstract
  12. Longitudinal Changes in Segmental Aortic Stiffness Determined by Cardiac Magnetic Resonance in Children and Young Adults With Connective Tissue Disorders (the Marfan, Loeys-Dietz, and Ehlers-Danlos Syndromes, and Nonspecific Connective Tissue Disorders). Am J Cardiol. 2017 Oct 01; 120(7):1214-1219. View abstract
  13. Design and Implementation of a Prospective Adult Congenital Heart Disease Biobank. World J Pediatr Congenit Heart Surg. 2016 11; 7(6):734-743. View abstract
  14. Predictive value of biomarkers of hepatic fibrosis in adult Fontan patients. J Heart Lung Transplant. 2017 Feb; 36(2):211-219. View abstract
  15. Response to Letters Regarding Article "Segmental Aortic Stiffness in Children and Young Adults With Connective Tissue Disorders: Relationships With Age, Aortic Size, Rate of Dilation, and Surgical Root Replacement". Circulation. 2016 Feb 16; 133(7):e405. View abstract
  16. Galectin-3 Is Elevated and Associated With Adverse Outcomes in Patients With Single-Ventricle Fontan Circulation. J Am Heart Assoc. 2016 Jan 11; 5(1). View abstract
  17. Recent Clinical Drug Trials Evidence in Marfan Syndrome and Clinical Implications. Can J Cardiol. 2016 Jan; 32(1):66-77. View abstract
  18. Segmental Aortic Stiffness in Children and Young Adults With Connective Tissue Disorders: Relationships With Age, Aortic Size, Rate of Dilation, and Surgical Root Replacement. Circulation. 2015 Aug 18; 132(7):595-602. View abstract
  19. Distinct effects of losartan and atenolol on vascular stiffness in Marfan syndrome. Vasc Med. 2015 Aug; 20(4):317-25. View abstract
  20. Portal and centrilobular hepatic fibrosis in Fontan circulation and clinical outcomes. J Heart Lung Transplant. 2015 Jul; 34(7):883-91. View abstract
  21. Pheochromocytoma and paraganglioma in cyanotic congenital heart disease. J Clin Endocrinol Metab. 2015 Apr; 100(4):1325-34. View abstract
  22. Transient elastography may identify Fontan patients with unfavorable hemodynamics and advanced hepatic fibrosis. Congenit Heart Dis. 2014 Sep-Oct; 9(5):438-47. View abstract
  23. Aortic valve dysfunction and aortic dilation in adults with coarctation of the aorta. Congenit Heart Dis. 2014 May-Jun; 9(3):235-43. View abstract
  24. MELD-XI score and cardiac mortality or transplantation in patients after Fontan surgery. Heart. 2013 Apr; 99(7):491-6. View abstract
  25. A shifting approach to management of the thoracic aorta in bicuspid aortic valve. J Thorac Cardiovasc Surg. 2013 Aug; 146(2):339-46. View abstract
  26. Bicuspid aortic valve and associated aortic dilation in the young. Heart. 2012 Jul; 98(13):1014-9. View abstract
  27. Increased vertebral artery tortuosity index is associated with adverse outcomes in children and young adults with connective tissue disorders. Circulation. 2011 Jul 26; 124(4):388-96. View abstract
  28. Mutations in smooth muscle alpha-actin (ACTA2) cause coronary artery disease, stroke, and Moyamoya disease, along with thoracic aortic disease. Am J Hum Genet. 2009 May; 84(5):617-27. View abstract
  29. Care of the adult with congenital heart disease. Curr Treat Options Cardiovasc Med. 2008 Dec; 10(6):505-15. View abstract
  30. Stacked proximal aortic cuffs: an "off-the-shelf" solution for treating focal thoracic aortic pathology. J Endovasc Ther. 2005 Oct; 12(5):574-8. View abstract