MEDICAL SERVICES

Departments

Languages

  • English

EDUCATION

Undergraduate Degree

  • Mount Holyoke College , 1979 , South Hadley , MA

Medical School

  • Yale University School of Medicine , 1983 , New Haven , CT

Internship

  • Yale-New Haven Hospital , 1984 , New Haven , CT

Residency

  • Massachusetts General Hospital , 1987 , Boston , MA

Fellowship

  • Massachusetts General Hospital , 1989 , Boston , MA

Philosophy of Care

I have been inspired by my patients and their families during my career. In particular, my research has focused on the effective care of children through characterization of direct or surrogate imaging markers to improve understanding of physiologic and metabolic profiles of pediatric brain tumors at diagnosis and after therapy.

During college, 2 medicine career exploration projects stimulated me to pursue medicine as my life work. A career in medicine includes my love of science and dedication to helping people. Patient care, teaching and research remain the hallmark of my career.

PROFESSIONAL HISTORY

Tina Young Poussaint, MD, FACR is Professor of Radiology at Harvard Medical School and at Boston Children’s Hospital has served as an Attending Neuroradiologist. She received her Bachelor of Arts degree from Mount Holyoke College (magna cum laude) where she was elected to the Phi Beta Kappa Society.  She received her MD with honors from Yale University School of Medicine where she was elected to the Alpha Omega Alpha Honor Medical Society. After an internship in pediatrics at Yale-New Haven Hospital (YNHH), she completed residency training in diagnostic radiology and a fellowship in neuroradiology at Massachusetts General Hospital (MGH).  After serving on the neuroradiology faculty at MGH, and she then joined the faculty at Boston Children’s Hospital.  Dr. Poussaint is board-certified in Diagnostic Radiology with a Certificate of Added Qualification in Neuroradiology.

 

Dr. Poussaint also serves as Director of Neuro-oncologic Imaging and as Director of the Pediatric Neuroradiology Fellowship. She is a Fellow of the American College of Radiology (ACR) and has served in several professional organizations including the ASNR, RSNA and SPR. She is a Past-President of the American Society of Pediatric Neuroradiology (ASPNR). Dr. Poussaint is the Chair of the Institutional Review Board of Boston Children’s Hospital.

CERTIFICATIONS

  • American Board of Radiology, Diagnostic Radiology
  • American Board of Radiology, Neuroradiology

PUBLICATIONS

Publications powered by Harvard Catalyst Profiles

  1. Quon JL, Bala W, Chen LC, Wright J, Kim LH, Han M, Shpanskaya K, Lee EH, Tong E, Iv M, Seekins J, Lungren MP, Braun KRM, Poussaint TY, Laughlin S, Taylor MD, Lober RM, Vogel H, Fisher PG, Grant GA, Ramaswamy V, Vitanza NA, Ho CY, Edwards MSB, Cheshier SH, Yeom KW. Deep Learning for Pediatric Posterior Fossa Tumor Detection and Classification: A Multi-Institutional Study. AJNR Am J Neuroradiol. 2020 09; 41(9):1718-1725. View abstract
  2. Baxter PA, Su JM, Onar-Thomas A, Billups CA, Li XN, Poussaint TY, Smith ER, Thompson P, Adesina A, Ansell P, Giranda V, Paulino A, Kilburn L, Quaddoumi I, Broniscer A, Blaney SM, Dunkel IJ, Fouladi M. A phase I/II study of veliparib (ABT-888) with radiation and temozolomide in newly diagnosed diffuse pontine glioma: a Pediatric Brain Tumor Consortium study. Neuro Oncol. 2020 06 09; 22(6):875-885. View abstract
  3. Erker C, Tamrazi B, Poussaint TY, Mueller S, Mata-Mbemba D, Franceschi E, Brandes AA, Rao A, Haworth KB, Wen PY, Goldman S, Vezina G, MacDonald TJ, Dunkel IJ, Morgan PS, Jaspan T, Prados MD, Warren KE. Response assessment in paediatric high-grade glioma: recommendations from the Response Assessment in Pediatric Neuro-Oncology (RAPNO) working group. Lancet Oncol. 2020 06; 21(6):e317-e329. View abstract
  4. Goldman S, Pollack IF, Jakacki RI, Billups CA, Poussaint TY, Adesina AM, Panigrahy A, Parsons DW, Broniscer A, Robinson GW, Robison NJ, Partap S, Kilburn LB, Onar-Thomas A, Dunkel IJ, Fouladi M. Phase II study of peginterferon alpha-2b for patients with unresectable or recurrent craniopharyngiomas: a Pediatric Brain Tumor Consortium report. Neuro Oncol. 2020 May 11. View abstract
  5. Jaimes C, Vajapeyam S, Brown D, Kao PC, Ma C, Greenspan L, Gupta N, Goumnerova L, Bandopahayay P, Dubois F, Greenwald NF, Zack T, Shapira O, Beroukhim R, Ligon KL, Chi S, Kieran MW, Wright KD, Poussaint TY. MR Imaging Correlates for Molecular and Mutational Analyses in Children with Diffuse Intrinsic Pontine Glioma. AJNR Am J Neuroradiol. 2020 05; 41(5):874-881. View abstract
  6. Vajapeyam S, Brown D, Billups C, Patay Z, Vezina G, Shiroishi MS, Law M, Baxter P, Onar-Thomas A, Fangusaro JR, Dunkel IJ, Poussaint TY. Advanced ADC Histogram, Perfusion, and Permeability Metrics Show an Association with Survival and Pseudoprogression in Newly Diagnosed Diffuse Intrinsic Pontine Glioma: A Report from the Pediatric Brain Tumor Consortium. AJNR Am J Neuroradiol. 2020 04; 41(4):718-724. View abstract
  7. Devine CA, Liu KX, Ioakeim-Ioannidou M, Susko M, Poussaint TY, Huisman TAGM, Aboian M, Brown D, Zaslowe-Dude C, Rao AD, Orlina LT, Rawal B, Mueller S, Marcus KJ, Terezakis SA, Braunstein SE, Haas-Kogan DA. Brainstem Injury in Pediatric Patients Receiving Posterior Fossa Photon Radiation. Int J Radiat Oncol Biol Phys. 2019 12 01; 105(5):1034-1042. View abstract
  8. Jaimes C, Poussaint TY. Primary Neoplasms of the Pediatric Brain. Radiol Clin North Am. 2019 Nov; 57(6):1163-1175. View abstract
  9. Poussaint TY. Lionel W. Young, MD. Radiology. 2019 Aug; 292(2):E3. View abstract
  10. Poussaint TY. Lionel W. Young, MD, FACR (1932-2019). Pediatr Radiol. 2019 Jun; 49(7):973-974. View abstract
  11. Sarma A, Poussaint TY. Indications and Imaging Modality of Choice in Pediatric Headache. Neuroimaging Clin N Am. 2019 May; 29(2):271-289. View abstract
  12. Ceschin R, Kocak M, Vajapeyam S, Pollack IF, Onar-Thomas A, Dunkel IJ, Poussaint TY, Panigrahy A. Quantifying radiation therapy response using apparent diffusion coefficient (ADC) parametric mapping of pediatric diffuse intrinsic pontine glioma: a report from the pediatric brain tumor consortium. J Neurooncol. 2019 May; 143(1):79-86. View abstract
  13. Fahey F, Christian P, Zukotynski K, Sexton-Stallone B, Kiss C, Clarke B, Onar-Thomas A, Poussaint TY. Use of a Qualification Phantom for PET Brain Imaging in a Multicenter Consortium: A Collaboration Between the Pediatric Brain Tumor Consortium and the SNMMI Clinical Trials Network. J Nucl Med. 2019 05; 60(5):677-682. View abstract
  14. Haas-Kogan D, Indelicato D, Paganetti H, Esiashvili N, Mahajan A, Yock T, Flampouri S, MacDonald S, Fouladi M, Stephen K, Kalapurakal J, Terezakis S, Kooy H, Grosshans D, Makrigiorgos M, Mishra K, Poussaint TY, Cohen K, Fitzgerald T, Gondi V, Liu A, Michalski J, Mirkovic D, Mohan R, Perkins S, Wong K, Vikram B, Buchsbaum J, Kun L. National Cancer Institute Workshop on Proton Therapy for Children: Considerations Regarding Brainstem Injury. Int J Radiat Oncol Biol Phys. 2018 05 01; 101(1):152-168. View abstract
  15. Warren KE, Vezina G, Poussaint TY, Warmuth-Metz M, Packer RJ, Kieran MW. Response to Harreld re: "Response assessment in medulloblastoma and leptomeningeal seeding tumors: recommendations from the Response Assessment in Pediatric Neuro-Oncology Committee". Neuro Oncol. 2018 01 10; 20(1):144-145. View abstract
  16. Warren KE, Vezina G, Poussaint TY, Warmuth-Metz M, Chamberlain MC, Packer RJ, Brandes AA, Reiss M, Goldman S, Fisher MJ, Pollack IF, Prados MD, Wen PY, Chang SM, Dufour C, Zurakowski D, Kortmann RD, Kieran MW. Response assessment in medulloblastoma and leptomeningeal seeding tumors: recommendations from the Response Assessment in Pediatric Neuro-Oncology committee. Neuro Oncol. 2018 01 10; 20(1):13-23. View abstract
  17. Vajapeyam S, Brown D, Johnston PR, Ricci KI, Kieran MW, Lidov HGW, Poussaint TY. Multiparametric Analysis of Permeability and ADC Histogram Metrics for Classification of Pediatric Brain Tumors by Tumor Grade. AJNR Am J Neuroradiol. 2018 Mar; 39(3):552-557. View abstract
  18. Kilburn LB, Kocak M, Baxter P, Poussaint TY, Paulino AC, McIntyre C, Lemenuel-Diot A, Lopez-Diaz C, Kun L, Chintagumpala M, Su JM, Broniscer A, Baker JN, Hwang EI, Fouladi M, Boyett JM, Blaney SM. A pediatric brain tumor consortium phase II trial of capecitabine rapidly disintegrating tablets with concomitant radiation therapy in children with newly diagnosed diffuse intrinsic pontine gliomas. Pediatr Blood Cancer. 2018 Feb; 65(2). View abstract
  19. Zukotynski KA, Vajapeyam S, Fahey FH, Kocak M, Brown D, Ricci KI, Onar-Thomas A, Fouladi M, Poussaint TY. Correlation of 18F-FDG PET and MRI Apparent Diffusion Coefficient Histogram Metrics with Survival in Diffuse Intrinsic Pontine Glioma: A Report from the Pediatric Brain Tumor Consortium. J Nucl Med. 2017 08; 58(8):1264-1269. View abstract
  20. Vajapeyam S, Stamoulis C, Ricci K, Kieran M, Poussaint TY. Automated Processing of Dynamic Contrast-Enhanced MRI: Correlation of Advanced Pharmacokinetic Metrics with Tumor Grade in Pediatric Brain Tumors. AJNR Am J Neuroradiol. 2017 Jan; 38(1):170-175. View abstract
  21. Salloum R, Hummel TR, Kumar SS, Dorris K, Li S, Lin T, Daryani VM, Stewart CF, Miles L, Poussaint TY, Stevenson C, Goldman S, Dhall G, Packer R, Fisher P, Pollack IF, Fouladi M, Boyett J, Drissi R. A molecular biology and phase II study of imetelstat (GRN163L) in children with recurrent or refractory central nervous system malignancies: a pediatric brain tumor consortium study. J Neurooncol. 2016 09; 129(3):443-451. View abstract
  22. Poussaint TY, Vajapeyam S, Ricci KI, Panigrahy A, Kocak M, Kun LE, Boyett JM, Pollack IF, Fouladi M. Apparent diffusion coefficient histogram metrics correlate with survival in diffuse intrinsic pontine glioma: a report from the Pediatric Brain Tumor Consortium. Neuro Oncol. 2016 05; 18(5):725-34. View abstract
  23. Poussaint TY, Huisman TA. Introduction to 'Advances in Pediatric Neuroradiology'. Pediatr Radiol. 2015 Sep; 45 Suppl 3:S369. View abstract
  24. Poussaint TY, Panigrahy A, Huisman TA. Pediatric brain tumors. Pediatr Radiol. 2015 Sep; 45 Suppl 3:S443-53. View abstract
  25. Kieran MW, Chi S, Goldman S, Onar-Thomas A, Poussaint TY, Vajapeyam S, Fahey F, Wu S, Turner DC, Stewart CF, Moses M, Packer RJ, Jakacki R, Banerjee A, Boyett JM, Fouladi M, Kun L. A phase I trial and PK study of cediranib (AZD2171), an orally bioavailable pan-VEGFR inhibitor, in children with recurrent or refractory primary CNS tumors. Childs Nerv Syst. 2015 Sep; 31(9):1433-45. View abstract
  26. Mulkern RV, Ricci KI, Vajapeyam S, Chenevert TL, Malyarenko DI, Kocak M, Poussaint TY. Pediatric brain tumor consortium multisite assessment of apparent diffusion coefficient z-axis variation assessed with an ice-water phantom. Acad Radiol. 2015 Mar; 22(3):363-9. View abstract
  27. Zukotynski K, Fahey F, Kocak M, Kun L, Boyett J, Fouladi M, Vajapeyam S, Treves T, Poussaint TY. 18F-FDG PET and MR imaging associations across a spectrum of pediatric brain tumors: a report from the pediatric brain tumor consortium. J Nucl Med. 2014 Sep; 55(9):1473-80. View abstract
  28. Byrd S, Davis B, Gibbs I, Poussaint TY, Simmons VJ. Diversity in diagnostic radiology. Radiology. 2014 Jul; 272(1):301-2. View abstract
  29. McCann ME, Schouten AN, Dobija N, Munoz C, Stephenson L, Poussaint TY, Kalkman CJ, Hickey PR, de Vries LS, Tasker RC. Infantile postoperative encephalopathy: perioperative factors as a cause for concern. Pediatrics. 2014 Mar; 133(3):e751-7. View abstract
  30. Gururangan S, Fangusaro J, Poussaint TY, McLendon RE, Onar-Thomas A, Wu S, Packer RJ, Banerjee A, Gilbertson RJ, Fahey F, Vajapeyam S, Jakacki R, Gajjar A, Goldman S, Pollack IF, Friedman HS, Boyett JM, Fouladi M, Kun LE. Efficacy of bevacizumab plus irinotecan in children with recurrent low-grade gliomas--a Pediatric Brain Tumor Consortium study. Neuro Oncol. 2014 Jan; 16(2):310-7. View abstract
  31. Dombi E, Ardern-Holmes SL, Babovic-Vuksanovic D, Barker FG, Connor S, Evans DG, Fisher MJ, Goutagny S, Harris GJ, Jaramillo D, Karajannis MA, Korf BR, Mautner V, Plotkin SR, Poussaint TY, Robertson K, Shih CS, Widemann BC. Recommendations for imaging tumor response in neurofibromatosis clinical trials. Neurology. 2013 Nov 19; 81(21 Suppl 1):S33-40. View abstract
  32. Fangusaro J, Gururangan S, Poussaint TY, McLendon RE, Onar-Thomas A, Warren KE, Wu S, Packer RJ, Banerjee A, Gilbertson RJ, Jakacki R, Gajjar A, Goldman S, Pollack IF, Friedman HS, Boyett JM, Kun LE, Fouladi M. Bevacizumab (BVZ)-associated toxicities in children with recurrent central nervous system tumors treated with BVZ and irinotecan (CPT-11): a Pediatric Brain Tumor Consortium Study (PBTC-022). Cancer. 2013 Dec 01; 119(23):4180-7. View abstract
  33. Zukotynski KA, Fahey FH, Vajapeyam S, Ng SS, Kocak M, Gururangan S, Kun LE, Poussaint TY. Exploratory evaluation of MR permeability with 18F-FDG PET mapping in pediatric brain tumors: a report from the Pediatric Brain Tumor Consortium. J Nucl Med. 2013 Aug; 54(8):1237-43. View abstract
  34. Brandão LA, Poussaint TY. Pediatric brain tumors. Neuroimaging Clin N Am. 2013 Aug; 23(3):499-525. View abstract
  35. Warren KE, Poussaint TY, Vezina G, Hargrave D, Packer RJ, Goldman S, Wen PY, Pollack IF, Zurakowski D, Kun LE, Prados MD, Rutkowski S, Kieran MW. Challenges with defining response to antitumor agents in pediatric neuro-oncology: a report from the response assessment in pediatric neuro-oncology (RAPNO) working group. Pediatr Blood Cancer. 2013 Sep; 60(9):1397-401. View abstract
  36. Li Y, Estroff JA, Khwaja O, Mehta TS, Poussaint TY, Robson CD, Feldman HA, Ware J, Levine D. Callosal dysgenesis in fetuses with ventriculomegaly: levels of agreement between imaging modalities and postnatal outcome. Ultrasound Obstet Gynecol. 2012 Nov; 40(5):522-9. View abstract
  37. Warren KE, Gururangan S, Geyer JR, McLendon RE, Poussaint TY, Wallace D, Balis FM, Berg SL, Packer RJ, Goldman S, Minturn JE, Pollack IF, Boyett JM, Kun LE. A phase II study of O6-benzylguanine and temozolomide in pediatric patients with recurrent or progressive high-grade gliomas and brainstem gliomas: a Pediatric Brain Tumor Consortium study. J Neurooncol. 2012 Feb; 106(3):643-9. View abstract
  38. Paldino MJ, Faerber EN, Poussaint TY. Imaging tumors of the pediatric central nervous system. Radiol Clin North Am. 2011 Jul; 49(4):589-616, v. View abstract
  39. Li Y, Estroff JA, Mehta TS, Robertson RL, Robson CD, Poussaint TY, Feldman HA, Ware J, Levine D. Ultrasound and MRI of fetuses with ventriculomegaly: can cortical development be used to predict postnatal outcome? AJR Am J Roentgenol. 2011 Jun; 196(6):1457-67. View abstract
  40. Pier DB, Levine D, Kataoka ML, Estroff JA, Werdich XQ, Ware J, Beeghly M, Poussaint TY, Duplessis A, Li Y, Feldman HA. Magnetic resonance volumetric assessments of brains in fetuses with ventriculomegaly correlated to outcomes. J Ultrasound Med. 2011 May; 30(5):595-603. View abstract
  41. Haas-Kogan DA, Banerjee A, Poussaint TY, Kocak M, Prados MD, Geyer JR, Fouladi M, Broniscer A, Minturn JE, Pollack IF, Packer RJ, Boyett JM, Kun LE. Phase II trial of tipifarnib and radiation in children with newly diagnosed diffuse intrinsic pontine gliomas. Neuro Oncol. 2011 Mar; 13(3):298-306. View abstract
  42. Poussaint TY, Kocak M, Vajapeyam S, Packer RI, Robertson RL, Geyer R, Haas-Kogan D, Pollack IF, Vezina G, Zimmerman R, Cha S, Patay Z, Boyett JM, Kun LE. MRI as a central component of clinical trials analysis in brainstem glioma: a report from the Pediatric Brain Tumor Consortium (PBTC). Neuro Oncol. 2011 Apr; 13(4):417-27. View abstract
  43. Pollack IF, Stewart CF, Kocak M, Poussaint TY, Broniscer A, Banerjee A, Douglas JG, Kun LE, Boyett JM, Geyer JR. A phase II study of gefitinib and irradiation in children with newly diagnosed brainstem gliomas: a report from the Pediatric Brain Tumor Consortium. Neuro Oncol. 2011 Mar; 13(3):290-7. View abstract
  44. Zukotynski KA, Fahey FH, Kocak M, Alavi A, Wong TZ, Treves ST, Shulkin BL, Haas-Kogan DA, Geyer JR, Vajapeyam S, Boyett JM, Kun LE, Poussaint TY. Evaluation of 18F-FDG PET and MRI associations in pediatric diffuse intrinsic brain stem glioma: a report from the Pediatric Brain Tumor Consortium. J Nucl Med. 2011 Feb; 52(2):188-95. View abstract
  45. Li Y, Sansgiri RK, Estroff JA, Mehta TS, Poussaint TY, Robertson RL, Robson CD, Feldman HA, Barnewolt C, Levine D. Outcome of fetuses with cerebral ventriculomegaly and septum pellucidum leaflet abnormalities. AJR Am J Roentgenol. 2011 Jan; 196(1):W83-92. View abstract
  46. Prabhu SP, Ng S, Vajapeyam S, Kieran MW, Pollack IF, Geyer R, Haas-Kogan D, Boyett JM, Kun L, Poussaint TY. DTI assessment of the brainstem white matter tracts in pediatric BSG before and after therapy: a report from the Pediatric Brain Tumor Consortium. Childs Nerv Syst. 2011 Jan; 27(1):11-8. View abstract
  47. Senapati GM, Levine D, Smith C, Estroff JA, Barnewolt CE, Robertson RL, Poussaint TY, Mehta TS, Werdich XQ, Pier D, Feldman HA, Robson CD. Frequency and cause of disagreements in imaging diagnosis in children with ventriculomegaly diagnosed prenatally. Ultrasound Obstet Gynecol. 2010 Nov; 36(5):582-95. View abstract
  48. Fahey FH, Kinahan PE, Doot RK, Kocak M, Thurston H, Poussaint TY. Variability in PET quantitation within a multicenter consortium. Med Phys. 2010 Jul; 37(7):3660-6. View abstract
  49. Beeghly M, Ware J, Soul J, du Plessis A, Khwaja O, Senapati GM, Robson CD, Robertson RL, Poussaint TY, Barnewolt CE, Feldman HA, Estroff JA, Levine D. Neurodevelopmental outcome of fetuses referred for ventriculomegaly. Ultrasound Obstet Gynecol. 2010 Apr; 35(4):405-16. View abstract
  50. Grace RF, Su H, Sena L, Poussaint TY, Heeney MM, Gutierrez A. Resolution of cerebral artery stenosis in a child with sickle cell anemia treated with hydroxyurea. Am J Hematol. 2010 Feb; 85(2):135-7. View abstract
  51. Rodriguez DP, Poussaint TY. Imaging of back pain in children. AJNR Am J Neuroradiol. 2010 May; 31(5):787-802. View abstract
  52. Kieran MW, Supko JG, Wallace D, Fruscio R, Poussaint TY, Phillips P, Pollack I, Packer R, Boyett JM, Blaney S, Banerjee A, Geyer R, Friedman H, Goldman S, Kun LE, Macdonald T. Phase I study of SU5416, a small molecule inhibitor of the vascular endothelial growth factor receptor (VEGFR) in refractory pediatric central nervous system tumors. Pediatr Blood Cancer. 2009 Feb; 52(2):169-76. View abstract
  53. Saad A, Folkerth R, Poussaint T, Smith E, Ligon K. Meningioangiomatosis associated with meningioma: a case report. Acta Cytol. 2009 Jan-Feb; 53(1):93-7. View abstract
  54. Mulkern RV, Forbes P, Dewey K, Osganian S, Clark M, Wong S, Ramamurthy U, Kun L, Poussaint TY. Establishment and results of a magnetic resonance quality assurance program for the pediatric brain tumor consortium. Acad Radiol. 2008 Sep; 15(9):1099-110. View abstract
  55. Levine D, Feldman HA, Tannus JF, Estroff JA, Magnino M, Robson CD, Poussaint TY, Barnewolt CE, Mehta TS, Robertson RL. Frequency and cause of disagreements in diagnoses for fetuses referred for ventriculomegaly. Radiology. 2008 May; 247(2):516-27. View abstract
  56. Williams G, Fahey FH, Treves ST, Kocak M, Pollack IF, Boyett JM, Kun LE, Poussaint TY. Exploratory evaluation of two-dimensional and three-dimensional methods of FDG PET quantification in pediatric anaplastic astrocytoma: a report from the Pediatric Brain Tumor Consortium (PBTC). Eur J Nucl Med Mol Imaging. 2008 Sep; 35(9):1651-8. View abstract
  57. Haas-Kogan DA, Banerjee A, Kocak M, Prados MD, Geyer JR, Fouladi M, McKnight T, Poussaint TY, Broniscer A, Blaney SM, Boyett JM, Kun LE. Phase I trial of tipifarnib in children with newly diagnosed intrinsic diffuse brainstem glioma. Neuro Oncol. 2008 Jun; 10(3):341-7. View abstract
  58. MacDonald TJ, Stewart CF, Kocak M, Goldman S, Ellenbogen RG, Phillips P, Lafond D, Poussaint TY, Kieran MW, Boyett JM, Kun LE. Phase I clinical trial of cilengitide in children with refractory brain tumors: Pediatric Brain Tumor Consortium Study PBTC-012. J Clin Oncol. 2008 Feb 20; 26(6):919-24. View abstract
  59. Gururangan S, Turner CD, Stewart CF, O'Shaughnessy M, Kocak M, Poussaint TY, Phillips PC, Goldman S, Packer R, Pollack IF, Blaney SM, Karsten V, Gerson SL, Boyett JM, Friedman HS, Kun LE. Phase I trial of VNP40101M (Cloretazine) in children with recurrent brain tumors: a pediatric brain tumor consortium study. Clin Cancer Res. 2008 Feb 15; 14(4):1124-30. View abstract
  60. Broniscer A, Gururangan S, MacDonald TJ, Goldman S, Packer RJ, Stewart CF, Wallace D, Danks MK, Friedman HS, Poussaint TY, Kun LE, Boyett JM, Gajjar A. Phase I trial of single-dose temozolomide and continuous administration of o6-benzylguanine in children with brain tumors: a pediatric brain tumor consortium report. Clin Cancer Res. 2007 Nov 15; 13(22 Pt 1):6712-8. View abstract
  61. Poussaint TY, Phillips PC, Vajapeyam S, Fahey FH, Robertson RL, Osganian S, Ramamurthy U, Mulkern RV, Treves ST, Boyett JM, Kun LE. The Neuroimaging Center of the Pediatric Brain Tumor Consortium-collaborative neuroimaging in pediatric brain tumor research: a work in progress. AJNR Am J Neuroradiol. 2007 Apr; 28(4):603-7. View abstract
  62. Liu AK, Marcus KJ, Fischl B, Grant PE, Poussaint TY, Rivkin MJ, Davis P, Tarbell NJ, Yock TI. Changes in cerebral cortex of children treated for medulloblastoma. Int J Radiat Oncol Biol Phys. 2007 Jul 15; 68(4):992-8. View abstract
  63. Marcus KJ, Astrakas LG, Zurakowski D, Zarifi MK, Mintzopoulos D, Poussaint TY, Anthony DC, De Girolami U, Black PM, Tarbell NJ, Tzika AA. Predicting survival of children with CNS tumors using proton magnetic resonance spectroscopic imaging biomarkers. Int J Oncol. 2007 Mar; 30(3):651-7. View abstract
  64. Pollack IF, Jakacki RI, Blaney SM, Hancock ML, Kieran MW, Phillips P, Kun LE, Friedman H, Packer R, Banerjee A, Geyer JR, Goldman S, Poussaint TY, Krasin MJ, Wang Y, Hayes M, Murgo A, Weiner S, Boyett JM. Phase I trial of imatinib in children with newly diagnosed brainstem and recurrent malignant gliomas: a Pediatric Brain Tumor Consortium report. Neuro Oncol. 2007 Apr; 9(2):145-60. View abstract
  65. Rodriguez DP, Poussaint TY. Neuroimaging of the child with developmental delay. Top Magn Reson Imaging. 2007 Feb; 18(1):75-92. View abstract
  66. Levine D, Cavazos C, Kazan-Tannus JF, McKenzie CA, Dialani V, Robson CD, Robertson RL, Poussaint TY, Busse RF, Rofsky NM. Evaluation of real-time single-shot fast spin-echo MRI for visualization of the fetal midline corpus callosum and secondary palate. AJR Am J Roentgenol. 2006 Dec; 187(6):1505-11. View abstract
  67. Fouladi M, Blaney SM, Poussaint TY, Freeman BB, McLendon R, Fuller C, Adesina AM, Hancock ML, Danks MK, Stewart C, Boyett JM, Gajjar A. Phase II study of oxaliplatin in children with recurrent or refractory medulloblastoma, supratentorial primitive neuroectodermal tumors, and atypical teratoid rhabdoid tumors: a pediatric brain tumor consortium study. Cancer. 2006 Nov 01; 107(9):2291-7. View abstract
  68. Turner CD, Chi S, Marcus KJ, MacDonald T, Packer RJ, Poussaint TY, Vajapeyam S, Ullrich N, Goumnerova LC, Scott RM, Briody C, Chordas C, Zimmerman MA, Kieran MW. Phase II study of thalidomide and radiation in children with newly diagnosed brain stem gliomas and glioblastoma multiforme. J Neurooncol. 2007 Mar; 82(1):95-101. View abstract
  69. Gururangan S, Petros WP, Poussaint TY, Hancock ML, Phillips PC, Friedman HS, Bomgaars L, Blaney SM, Kun LE, Boyett JM. Phase I trial of intrathecal spartaject busulfan in children with neoplastic meningitis: a Pediatric Brain Tumor Consortium Study (PBTC-004). Clin Cancer Res. 2006 Mar 01; 12(5):1540-6. View abstract
  70. Poussaint TY, Rodriguez D. Advanced neuroimaging of pediatric brain tumors: MR diffusion, MR perfusion, and MR spectroscopy. Neuroimaging Clin N Am. 2006 Feb; 16(1):169-92, ix. View abstract
  71. Anselm IA, Anselm IM, Alkuraya FS, Salomons GS, Jakobs C, Fulton AB, Mazumdar M, Rivkin M, Frye R, Poussaint TY, Marsden D. X-linked creatine transporter defect: a report on two unrelated boys with a severe clinical phenotype. J Inherit Metab Dis. 2006 Feb; 29(1):214-9. View abstract
  72. Baser ME, Poussaint TY. Age associated increase in the prevalence of chromosome 22q loss of heterozygosity in histological subsets of benign meningioma. J Med Genet. 2006 Mar; 43(3):285-7. View abstract
  73. Fleischman A, Brue C, Poussaint TY, Kieran M, Pomeroy SL, Goumnerova L, Scott RM, Cohen LE. Diencephalic syndrome: a cause of failure to thrive and a model of partial growth hormone resistance. Pediatrics. 2005 Jun; 115(6):e742-8. View abstract
  74. Lim R, Jaramillo D, Poussaint TY, Chang Y, Korf B. Superficial neurofibroma: a lesion with unique MRI characteristics in patients with neurofibromatosis type 1. AJR Am J Roentgenol. 2005 Mar; 184(3):962-8. View abstract
  75. Zacharia TT, Jaramillo D, Poussaint TY, Korf B. MR imaging of abdominopelvic involvement in neurofibromatosis type 1: a review of 43 patients. Pediatr Radiol. 2005 Mar; 35(3):317-22. View abstract
  76. Sun Y, Schmidt NO, Schmidt K, Doshi S, Rubin JB, Mulkern RV, Carroll R, Ziu M, Erkmen K, Poussaint TY, Black P, Albert M, Burstein D, Kieran MW. Perfusion MRI of U87 brain tumors in a mouse model. Magn Reson Med. 2004 May; 51(5):893-9. View abstract
  77. Rodriguez D, Young Poussaint T. Neuroimaging findings in neurofibromatosis type 1 and 2. Neuroimaging Clin N Am. 2004 May; 14(2):149-70, vii. View abstract
  78. Tzika AA, Astrakas LG, Zarifi MK, Zurakowski D, Poussaint TY, Goumnerova L, Tarbell NJ, Black PM. Spectroscopic and perfusion magnetic resonance imaging predictors of progression in pediatric brain tumors. Cancer. 2004 Mar 15; 100(6):1246-56. View abstract
  79. Caruso PA, Poussaint TY, Tzika AA, Zurakowski D, Astrakas LG, Elias ER, Bay C, Irons MB. MRI and 1H MRS findings in Smith-Lemli-Opitz syndrome. Neuroradiology. 2004 Jan; 46(1):3-14. View abstract
  80. Heath JA, Turner CD, Poussaint TY, Scott RM, Goumnerova L, Kieran MW. Chemotherapy for progressive low-grade gliomas in children older than ten years: the Dana-Farber experience. Pediatr Hematol Oncol. 2003 Oct-Nov; 20(7):497-504. View abstract
  81. Jaramillo D, Poussaint TY, Grottkau BE. Scoliosis: evidence-based diagnostic evaluation. Neuroimaging Clin N Am. 2003 May; 13(2):335-41, xii. View abstract
  82. Poussaint TY, Jaramillo D, Chang Y, Korf B. Interobserver reproducibility of volumetric MR imaging measurements of plexiform neurofibromas. AJR Am J Roentgenol. 2003 Feb; 180(2):419-23. View abstract
  83. Zarifi MK, Astrakas LG, Poussaint TY, Plessis Ad Ad, Zurakowski D, Tzika AA. Prediction of adverse outcome with cerebral lactate level and apparent diffusion coefficient in infants with perinatal asphyxia. Radiology. 2002 Dec; 225(3):859-70. View abstract
  84. Poussaint TY, Moeller KK. Imaging of pediatric head trauma. Neuroimaging Clin N Am. 2002 May; 12(2):271-94, ix. View abstract
  85. Faerber EN, Poussaint TY. Magnetic resonance of metabolic and degenerative diseases in children. Top Magn Reson Imaging. 2002 Feb; 13(1):3-21. View abstract
  86. Poussaint TY, Moeller K. Pediatric Head Trauma. Neuroimaging Clin No Am. 2002; In Press. View abstract
  87. Faerber EN, Poussaint TY. MR of Metabolic and Degenerative Disease in Childhood. Topics in MRI. 2002. View abstract
  88. O'Tuama LA, Poussaint TY. Thallium-201 single-photon emission CT in recurrent squamous cell carcinoma of the head and neck. AJNR Am J Neuroradiol. 2002 Jan; 23(1):174-5. View abstract
  89. Poussaint TY. Magnetic resonance imaging of pediatric brain tumors: state of the art. Top Magn Reson Imaging. 2001 Dec; 12(6):411-33. View abstract
  90. Poussaint TY. Magnetic resonance imaging (MRI) is one of the most important imaging modalities in pediatric neuroradiology. Top Magn Reson Imaging. 2001 Dec; 12(6):359. View abstract
  91. Poussaint, TY. Editorial. Topics in MRI. 2001; 359. View abstract
  92. Poussaint, TY. MR Imaging of Pediatric Brain Tumors: State of the Art. Topics in MRI. 2001; 12: 411-433. View abstract
  93. O'Tuama LA,Poussaint TY. Thallum-201 Single-Proton Emission CT versus CT for the Detection of Recurrent Squamous Cell Carcinoma of the Head and Neck. AJNR Am J Neuroradiol. 2001; 22(1). View abstract
  94. Madsen JR, Poussaint TY, Barnes PD. Congenital Malformations of the Cerebellum and Posterior Fossa: Radiographic Diagnosis and Surgical Treatment. . The Cerebellum and Its Disorders. 2001. View abstract
  95. Young Poussaint T and Barnes PD. Imaging of the Developmentally Delayed Child. Magnetic Resonance Imaging Clinics of North America. 2001; 999-119. View abstract
  96. Zarifi MK, Tzika AA, Astrakas LG, Poussaint TY, Anthony DC, Darras BT. Magnetic resonance spectroscopy and magnetic resonance imaging findings in Krabbe's disease. J Child Neurol. 2001 Jul; 16(7):522-6. View abstract
  97. Tzika AA, Zurakowski D, Poussaint TY, Goumnerova L, Astrakas LG, Barnes PD, Anthony DC, Billett AL, Tarbell NJ, Scott RM, Black PM. Proton magnetic spectroscopic imaging of the child's brain: the response of tumors to treatment. Neuroradiology. 2001 Feb; 43(2):169-77. View abstract
  98. Poussaint TY, Fox JW, Dobyns WB, Radtke R, Scheffer IE, Berkovic SF, Barnes PD, Huttenlocher PR, Walsh CA. Periventricular nodular heterotopia in patients with filamin-1 gene mutations: neuroimaging findings. Pediatr Radiol. 2000 Nov; 30(11):748-55. View abstract
  99. Caruso P, Poussaint TY. Case Report: Supratentorial intraventricular PNET. ACR Learning File CD-ROM Series. 2000. View abstract
  100. Caruso P, Poussaint TY. Case Report: Supratentorial ependymoma. ACR Learning File CD-ROM Series. 2000. View abstract
  101. Drubach LA, Connolly LP, Poussaint TY, Faul PN, Treves ST. Role of intraoperative skeletal scintigraphy in the localization of osteoblastomas. Clin Nucl Med. 2000 Oct; 25(10):819-20. View abstract
  102. Siffert J, Poussaint TY, Goumnerova LC, Scott RM, LaValley B, Tarbell NJ, Pomeroy SL. Neurological dysfunction associated with postoperative cerebellar mutism. J Neurooncol. 2000 May; 48(1):75-81. View abstract
  103. Poussaint, TY. Neuroradiology portion of Pediatric Radiology Chapter . Mosby Yearbook. 1999. View abstract
  104. Young Poussaint T, Yousuf N, Barnes PD, Anthony DC, Zurakowski D, Scott RM, Tarbell NJ. Cervicomedullary astrocytomas of childhood: clinical and imaging follow-up. Pediatr Radiol. 1999 Sep; 29(9):662-8. View abstract
  105. Santiago Medina L, al-Orfali M, Zurakowski D, Poussaint TY, DiCanzio J, Barnes PD. Occult lumbosacral dysraphism in children and young adults: diagnostic performance of fast screening and conventional MR imaging. Radiology. 1999 Jun; 211(3):767-71. View abstract
  106. Korf BR, Schneider G, Poussaint TY. Structural anomalies revealed by neuroimaging studies in the brains of patients with neurofibromatosis type 1 and large deletions. Genet Med. 1999 May-Jun; 1(4):136-40. View abstract
  107. Poussaint TY, Gudas T, Barnes PD. Imaging of neuroendocrine disorders of childhood. Neuroimaging Clin N Am. 1999 Feb; 9(1):157-75. View abstract
  108. Kim FM, Poussaint TY, Barnes PD. Neuroimaging of scoliosis in childhood. Neuroimaging Clin N Am. 1999 Feb; 9(1):195-221. View abstract
  109. Oestreich AE, Young LW, Poussaint TY. Scoliosis circa 2000: radiologic imaging perspective. II. Treatment and follow-up. Skeletal Radiol. 1998 Dec; 27(12):651-6. View abstract
  110. Oestreich AE, Young LW, Young Poussaint T. Scoliosis circa 2000: radiologic imaging perspective. I. Diagnosis and pretreatment evaluation. Skeletal Radiol. 1998 Nov; 27(11):591-605. View abstract
  111. O'Tuama LA, Poussaint TY, Anthony DC, Treves ST. Childhood brain tumor: neuroimaging correlated with disease outcome. Pediatr Neurol. 1998 Oct; 19(4):259-62. View abstract
  112. Madsen JR, Vallat AV, Poussaint TY, Scott RM, De Girolami U, Anthony DC. Focal cortical dysplasia with glioproliferative changes causing seizures: report of 3 cases. Pediatr Neurosurg. 1998 May; 28(5):261-6. View abstract
  113. Poussaint TY, Kowal JR, Barnes PD, Zurakowski D, Anthony DC, Goumnerova L, Tarbell NJ. Tectal tumors of childhood: clinical and imaging follow-up. AJNR Am J Neuroradiol. 1998 May; 19(5):977-83. View abstract
  114. Medina LS, Zurakowski D, Strife KR, Robertson RL, Poussaint TY, Barnes PD. Efficacy of fast screening MR in children and adolescents with suspected intracranial tumors. AJNR Am J Neuroradiol. 1998 Mar; 19(3):529-34. View abstract
  115. Poussaint TY, Barnes PD, Nichols K, Anthony DC, Cohen L, Tarbell NJ, Goumnerova L. Diencephalic syndrome: clinical features and imaging findings. AJNR Am J Neuroradiol. 1997 Sep; 18(8):1499-505. View abstract
  116. Robertson RL, Burrows PE, Barnes PD, Robson CD, Poussaint TY, Scott RM. Angiographic changes after pial synangiosis in childhood moyamoya disease. AJNR Am J Neuroradiol. 1997 May; 18(5):837-45. View abstract
  117. Poussaint TY, Ball WS, Jr., Barnes PD. Imaging of the spine and spinal cord. Practical pediatric imaging. Diagnostic radiology of infants and children. 1997; 259-325.. View abstract
  118. Barnes PD, Robertson RL, Young Poussaint T. Structural imaging of CNS tumors. Cancer of the nervous system. 1997; 54-97. View abstract
  119. Poussaint TY, Barnes PD, Anthony DC, Spack N, Scott RM, Tarbell NJ. Hemorrhagic pituitary adenomas of adolescence. AJNR Am J Neuroradiol. 1996 Nov-Dec; 17(10):1907-12. View abstract
  120. Levy HL, Lobbregt D, Barnes PD, Poussaint TY. Maternal phenylketonuria: magnetic resonance imaging of the brain in offspring. J Pediatr. 1996 Jun; 128(6):770-5. View abstract
  121. Steingard RJ, Renshaw PF, Yurgelun-Todd D, Appelmans KE, Lyoo IK, Shorrock KL, Bucci JP, Cesena M, Abebe D, Zurakowski D, Poussaint TY, Barnes P. Structural abnormalities in brain magnetic resonance images of depressed children. J Am Acad Child Adolesc Psychiatry. 1996 Mar; 35(3):307-11. View abstract
  122. Barnes PD, Robson CD, Robertson RL, Poussaint TY. Pediatric orbital and visual pathway lesions. Neuroimaging Clin N Am. 1996 Feb; 6(1):179-98. View abstract
  123. Poussaint TY, Siffert J, Barnes PD, Pomeroy SL, Goumnerova LC, Anthony DC, Sallan SE, Tarbell NJ. Hemorrhagic vasculopathy after treatment of central nervous system neoplasia in childhood: diagnosis and follow-up. AJNR Am J Neuroradiol. 1995 Apr; 16(4):693-9. View abstract
  124. Chiang V, Adelson PD, Poussaint TY, Hand M, Churchwell KB. Brain abscesses caused by Clostridium septicum as a complication of hemolytic-uremic syndrome. Pediatr Infect Dis J. 1995 Jan; 14(1):72-4. View abstract
  125. Woods BT, Brennan S, Yurgelun-Todd D, Young T, Panzarino P. MRI abnormalities in major psychiatric disorders: an exploratory comparative study. J Neuropsychiatry Clin Neurosci. 1995; 7(1):49-53. View abstract
  126. Barnes PD, Young Poussaint T, Robertson RL. Imaging of the pediatric spine and spinal neuraxis. Spine: state of the art reviews. Spinal imaging. 1995; 73-92. View abstract
  127. Appignani BA, Jaramillo D, Barnes PD, Poussaint TY. Dysraphic myelodysplasias associated with urogenital and anorectal anomalies: prevalence and types seen with MR imaging. AJR Am J Roentgenol. 1994 Nov; 163(5):1199-203. View abstract
  128. Barnes PD, Poussaint TY, Burrows PE. Imaging of pediatric central nervous system infections. Neuroimaging Clin N Am. 1994 May; 4(2):367-91. View abstract
  129. Barnes P, Poussaint TY, Burrows PE. Imaging of pediatric CNS infections. Neuroimaging Clin No Am. 1994; 4:367-91. View abstract
  130. Johnson LA, Pearlman JD, Miller CA, Young TI, Thulborn KR. MR quantification of cerebral ventricular volume using a semiautomated algorithm. AJNR Am J Neuroradiol. 1993 Nov-Dec; 14(6):1373-8. View abstract
  131. Lopez-Bresnahan MV, Kearse LA, Yanez P, Young TI. Anterior communicating artery collateral flow protection against ischemic change during carotid endarterectomy. J Neurosurg. 1993 Sep; 79(3):379-82. View abstract
  132. Strand RD, Barnes PD, Poussaint TY, Estroff JA, Burrows PE. Cystic retrocerebellar malformations: unification of the Dandy-Walker complex and the Blake's pouch cyst. Pediatr Radiol. 1993; 23(4):258-60. View abstract
  133. Young TI. MR and CT imaging in multiple sclerosis. Current practice in radiology. 1993; 502-511. View abstract
  134. Young TI. Magnetic resonance imaging of spine.[Book Review]. Year Book Med Pub. 1991; 75:666. View abstract
  135. Teitelbaum GP, Lin MC, Watanabe AT, Norfray JF, Young TI, Bradley WG. Ferromagnetism and MR imaging: safety of carotid vascular clamps. AJNR Am J Neuroradiol. 1990 Mar-Apr; 11(2):267-72. View abstract
  136. Smith CG, Paradise JL, Young TI. Modified schema for classifying positive-pressure tympanograms. Pediatrics. 1982 Mar; 69(3):351-4. View abstract
  137. Greene MH, Young TI, Clark WH. Malignant melanoma in renal-transplant recipients. Lancet. 1981 May 30; 1(8231):1196-9. View abstract
  138. Greene MH, Young TI. Polyethylene glycol in suppositories: carcinogenic? Ann Intern Med. 1980 Nov; 93(5):781. View abstract
  139. Tzika AA, Astrakas LG, Kieran M, Zurakowski D, Zarifi MK, Poussaint T. Choline to N-Acetylaspartate Ratio is Predictive of Pediatric BrainTumor Progression . View abstract
  140. Tzika AA, Zarifi MK, Goumnerova L, Astrakas LG, Zurakowski D, Poussaint TY, Anthony DA, Scott RM, Black PM . Neuroimaging of Pediatric Brain Tumors: Gd-DTPA Enhanced, Hemodynamic and Diffusion MR Imaging Compared to MR Spectroscopic Imaging. . AJNR, In Press. View abstract
  141. Astrakas L, Tzika A, Poussaint T, Kieran M. MRSI of Antiangiogenesis/Radiation in Pediatric Gliomas . View abstract
  142. Zarifi M, Astrakas L, Zurakowski D, Poussaint T, duPlessis A, Tzika A . Predicting Clinical Outcome in Perinatal Asphyxia by MRI and MRS. View abstract
  143. Poussaint TY, Caruso P, Anthony D, Connolly L, Kim F, Riviello J. Rasmussen Encephalitis: typical and atypical MRI findings with pathologic correlation. View abstract
  144. Zarifi M, Astrakas L, Zurakowski D, Poussaint T, Duplessis A, Tzika A . Predicting Clinical Outcome in Infants with Perinatal Asphyxia. View abstract
  145. Zarifi M, Astrakas L, Zurakowski D, Poussaint T, duPlessis A, Tzika A . Predicting Clinical Outcome in Perinatal Asphyxia by MRI and MRS. View abstract
  146. Zarifi M, Astrakas L, Zurakowski D, Poussaint T, Duplessis A, Tzika A . Predicting Clinical Outcome in Infants with Perinatal Asphyxia. View abstract
  147. Tzika A, Cheng L, Astrakas L, Zarifi M, Poussaint T, Goumnerova L, Zurakowski D, Anthony D, Gonzalez G. . Comparison of in Vivo proton MRS of pediatric brain tumors with ex vivo Magic Angle Spinning MRS of intact biopsy tumor samples . View abstract
  148. Astrakas L, Tzika A, Poussaint T, Kieran M. MRSI of Antiangiogenesis/Radiation in Pediatric Gliomas. View abstract
  149. Poussaint TY, Caruso P, Anthony D, Connolly L, Kim F, Riviello . Rasmussen Encephalitis: typical and atypical MRI findings with pathologic correlation. View abstract
  150. Poussaint TY, Tzika AA, Caruso P, Astrakas L, Elias ER, Irons M. . MR Imaging and MR Spectroscopy Findings in Smith-Lemli-Opitz Syndrome. View abstract
  151. Poussaint TY, Tzika AA, Caruso P, Astrakas L, Elias ER, Irons M. MR Imaging and MR Spectroscopy Findings in Smith-Lemli-Opitz Syndrome. View abstract
  152. Tzika AA, Astrakas LG, Kieran M, Zurakowski D, Zarifi MK, Poussaint T. Choline to N-Acetylaspartate Ratio is Predictive of Pediatric Brain Tumor Progression. View abstract
  153. Tzika A, Cheng L, Astrakas L, Zarifi M, Poussaint T, Goumnerova L, Zurakowski D, Anthony D, Gonzalez G . Comparison of in Vivo proton MRS of pediatric brain tumors with ex vivo Magic Angle Spinning MRS of intact biopsy tumor samples . View abstract