MEDICAL SERVICES

EDUCATION

Undergraduate Degree

  • Merrimack College , 2002 , North Andover , MA

Medical School

  • Jefferson Medical College, Thomas Jefferson University , 2009 , Philadelphia , PA

Internship

  • Fletcher Allen Health Care, University of Vermont , 2010 , Burlington , VT

Residency

Pediatrics
  • Fletcher Allen Health Care, University of Vermont , 2012 , Burlington , VT

Fellowship

Allergy & Immunology
  • Boston Children's Hospital , 2014 , Boston , MA

Fellowship

  • Harvard Neonatal-Perinatal Medicine Training Program , 2016 , Boston , MA

Philosophy of Care

In the Boston Children’s Hospital (BCH) Neonatal Intensive Care Unit (NICU) our philosophy is to ensure that every patient receives the best care for the best possible outcomes. We consider our “patient” to be the baby and the family; we are constantly striving to serve the needs of both. This requires a team based approach with all members being essential. My passion is taking care of critically ill babies and their families in a team-centered environment, and that is why I am a neonatologist at Boston Children’s Hospital. I help babies and infants with respiratory failure, congenital heart disease, prematurity, complex surgical problems, and a host of other diseases, from the common to the rare. In addition, I oversee infection control for the unit and make sure we are always doing our best to minimize the risk of hospital-acquired infections.

PROFESSIONAL HISTORY

Dr. Amy O’Connell is a physician scientist who has clinical training in pediatrics, allergy/immunology, and neonatology. She attended medical and graduate school at what is now Jefferson University in Philadelphia and did her pediatrics residency at the University of Vermont. She has been in Boston since 2012 when she started her fellowship training at Boston Children’s Hospital, completing fellowships in allergy/immunology in 2014 and neonatal perinatal medicine in 2017. Her research focuses on developmental biology and neonatal immunity. The biggest focuses of the laboratory are intestinal stem cell biology and immune maturation in former preterm infants.

CERTIFICATIONS

  • American Board of Pediatrics, General Pediatrics
  • American Board of Pediatrics, Neonatal-Perinatal Medicine

PUBLICATIONS

Publications powered by Harvard Catalyst Profiles

  1. Novel variants in the stem cell niche factor WNT2B define the disease phenotype as a congenital enteropathy with ocular dysgenesis. Eur J Hum Genet. 2021 Feb 01. View abstract
  2. Gene and Stem Cell Therapies for Fetal Care: A Review. JAMA Pediatr. 2020 10 01; 174(10):985-991. View abstract
  3. Primary immunodeficiency testing in a Massachusetts tertiary care NICU: persistent challenges in the extremely premature population. Pediatr Res. 2021 Feb; 89(3):549-553. View abstract
  4. Hypersensitivity to tetracyclines: Skin testing, graded challenge, and desensitization regimens. Ann Allergy Asthma Immunol. 2020 06; 124(6):589-593. View abstract
  5. Risk-factors Associated With Poor Outcomes in VEO-IBD Secondary to XIAP Deficiency: A Case Report and Literature Review. J Pediatr Gastroenterol Nutr. 2019 07; 69(1):e13-e18. View abstract
  6. Mammalian Hbs1L deficiency causes congenital anomalies and developmental delay associated with Pelota depletion and 80S monosome accumulation. PLoS Genet. 2019 02; 15(2):e1007917. View abstract
  7. Primary Immunodeficiency in the NICU. Neoreviews. 2019 02; 20(2):e67-e78. View abstract
  8. Duplicate skin prick testing in the assessment of food allergy. J Allergy Clin Immunol Pract. 2019 Feb; 7(2):675-677. View abstract
  9. Neonatal-Onset Chronic Diarrhea Caused by Homozygous Nonsense WNT2B Mutations. Am J Hum Genet. 2018 07 05; 103(1):131-137. View abstract
  10. NeoReviews. Perinatal Transient Myeloproliferative Disorder in Trisomy 21. 2016; 17(11):e636-e644. View abstract
  11. Next generation sequencing reveals skewing of the T and B cell receptor repertoires in patients with wiskott-Aldrich syndrome. Front Immunol. 2014; 5:340. View abstract
  12. Paravertebral mushroom: identification of a novel species of Phellinus as a human pathogen in chronic granulomatous disease. J Clin Microbiol. 2014 Jul; 52(7):2726-9. View abstract
  13. Successful desensitization to brentuximab vedotin after anaphylaxis. Clin Lymphoma Myeloma Leuk. 2014 Apr; 14(2):e73-5. View abstract
  14. Human and mouse macrophages collaborate with neutrophils to kill larval Strongyloides stercoralis. Infect Immun. 2013 Sep; 81(9):3346-55. View abstract
  15. Major basic protein from eosinophils and myeloperoxidase from neutrophils are required for protective immunity to Strongyloides stercoralis in mice. Infect Immun. 2011 Jul; 79(7):2770-8. View abstract
  16. Soluble extract from the nematode Strongyloides stercoralis induces CXCR2 dependent/IL-17 independent neutrophil recruitment. Microbes Infect. 2011 Jun; 13(6):536-44. View abstract
  17. IL-4(-/-) mice with lethal Mesocestoides corti infections--reduced Th2 cytokines and alternatively activated macrophages. Parasite Immunol. 2009 Dec; 31(12):741-9. View abstract