MEDICAL SERVICES

Departments

Languages

  • English

EDUCATION

Medical School

  • Harvard Medical School , 1997 , Boston , MA

Residency

  • Boston Children's Hospital , 2002 , Boston , MA

Fellowship

  • Boston Children's Hospital , 2005 , Boston , MA

Graduate Degree

Master of Public Health (MPH)
  • Harvard School of Public Health , 2005 , Boston , MA

CERTIFICATIONS

  • American Board of Pediatrics, Pediatric Emergency Medicine
  • American Board of Pediatrics, General Pediatrics

PUBLICATIONS

Publications powered by Harvard Catalyst Profiles

  1. Kaji AH, Meurer WJ, Napper T, Nigrovic LE, Mower WR, Schriger DL, Cooper RJ. State of the Journal: Women First Authors, Peer Reviewers, and Editorial Board Members at Annals of Emergency Medicine. Ann Emerg Med. 2019 Jul 04. View abstract
  2. Aronson PL, Shabanova V, Shapiro ED, Wang ME, Nigrovic LE, Pruitt CM, DePorre AG, Leazer RC, Desai S, Sartori LF, Marble RD, Rooholamini SN, McCulloh RJ, Woll C, Balamuth F, Alpern ER, Shah SS, Williams DJ, Browning WL, Shah N, Neuman MI. A Prediction Model to Identify Febrile Infants =60 Days at Low Risk of Invasive Bacterial Infection. Pediatrics. 2019 Jul; 144(1). View abstract
  3. Aronson PL, Cruz AT, Freedman SB, Balamuth F, Grether-Jones KL, Lyons TW, Fleming AH, Louie J, Mistry RD, Garro AC, Shah SS, Nigrovic LE. Association of Herpes Simplex Virus Testing with Hospital Length of Stay for Infants =60 Days of Age Undergoing Evaluation for Meningitis. J Hosp Med. 2019 08 01; 14(8):492-495. View abstract
  4. Garro A, Bennett J, Balamuth F, Levas MN, Neville D, Branda JC, Maulden AB, Lantos PM, Nigrovic LE. Positive 2-Tiered Lyme Disease Serology is Uncommon in Asymptomatic Children Living in Endemic Areas of the United States. Pediatr Infect Dis J. 2019 May; 38(5):e105-e107. View abstract
  5. Zanetto L, Da Dalt L, Daverio M, Dunning J, Frigo AC, Nigrovic LE, Bressan S. Systematic review and meta-analysis found significant risk of brain injury and neurosurgery in alert children after a post-traumatic seizure. Acta Paediatr. 2019 Apr 05. View abstract
  6. Kuppermann N, Dayan PS, Levine DA, Vitale M, Tzimenatos L, Tunik MG, Saunders M, Ruddy RM, Roosevelt G, Rogers AJ, Powell EC, Nigrovic LE, Muenzer J, Linakis JG, Grisanti K, Jaffe DM, Hoyle JD, Greenberg R, Gattu R, Cruz AT, Crain EF, Cohen DM, Brayer A, Borgialli D, Bonsu B, Browne L, Blumberg S, Bennett JE, Atabaki SM, Anders J, Alpern ER, Miller B, Casper TC, Dean JM, Ramilo O, Mahajan P. A Clinical Prediction Rule to Identify Febrile Infants 60 Days and Younger at Low Risk for Serious Bacterial Infections. JAMA Pediatr. 2019 Apr 01; 173(4):342-351. View abstract
  7. Nigrovic LE, Neville DN, Balamuth F, Bennett JE, Levas MN, Garro AC. A minority of children diagnosed with Lyme disease recall a preceding tick bite. Ticks Tick Borne Dis. 2019 04; 10(3):694-696. View abstract
  8. Maulden AB, Garro AC, Balamuth F, Levas MN, Bennett JE, Neville DN, Branda JA, Nigrovic LE. Two-Tier Lyme Disease Serology Test Results Can Vary According to the Specific First-Tier Test Used. J Pediatric Infect Dis Soc. 2019 Feb 22. View abstract
  9. Winn AS, Nigrovic LE, Lovejoy FH, Sandora TJ. Impact of a Resident Research Grant on Scholarly Output During Pediatric Residency. Acad Pediatr. 2019 May - Jun; 19(4):477-479. View abstract
  10. Aronson PL, McCulloh RJ, Tieder JS, Nigrovic LE, Leazer RC, Alpern ER, Feldman EA, Balamuth F, Browning WL, Neuman MI. Application of the Rochester Criteria to Identify Febrile Infants With Bacteremia and Meningitis. Pediatr Emerg Care. 2019 Jan; 35(1):22-27. View abstract
  11. Rees CA, Cruz AT, Freedman SB, Mahajan P, Uspal NG, Okada P, Aronson PL, Thompson AD, Ishimine PT, Schmidt SM, Kuppermann N, Nigrovic LE. Application of the Bacterial Meningitis Score for Infants Aged 0 to 60 Days. J Pediatric Infect Dis Soc. 2018 Dec 10. View abstract
  12. Nigrovic LE, Lipsett SC, Molins CR, Wormser GP, Bennett JE, Garro AC, Levas MN, Balamuth F, Neville D, Lingampalli N, Robinson WH, Branda JA. Higher C6 enzyme immunoassay index values correlate with a diagnosis of noncutaneous Lyme disease. Diagn Microbiol Infect Dis. 2019 Jun; 94(2):160-164. View abstract
  13. Stoner MJ, Mahajan P, Bressan S, Lam SHF, Chumpitazi CE, Kornblith AE, Linakis SW, Roland D, Freedman SB, Nigrovic LE, Denninghoff K, Ishimine P, Kuppermann N. Pediatric Emergency Care Research Networks: A Research Agenda. Acad Emerg Med. 2018 Dec; 25(12):1336-1344. View abstract
  14. Rees CA, Nigrovic LE. Oral Ondansetron to Reduce Intravenous Fluid Rehydration: Context Matters. Ann Emerg Med. 2019 Mar; 73(3):266-268. View abstract
  15. Aronson PL, Wang ME, Shapiro ED, Shah SS, DePorre AG, McCulloh RJ, Pruitt CM, Desai S, Nigrovic LE, Marble RD, Leazer RC, Rooholamini SN, Sartori LF, Balamuth F, Woll C, Neuman MI. Risk Stratification of Febrile Infants =60 Days Old Without Routine Lumbar Puncture. Pediatrics. 2018 12; 142(6). View abstract
  16. Balamuth F, Cruz AT, Freedman SB, Ishimine PT, Garro A, Curtis S, Grether-Jones KL, Miller AS, Uspal NG, Schmidt SM, Shah SS, Nigrovic LE. Test Characteristics of Cerebrospinal Fluid Gram Stain to Identify Bacterial Meningitis in Infants Younger Than 60 Days. Pediatr Emerg Care. 2018 Nov 12. View abstract
  17. Paydar-Darian N, Kimia AA, Monuteaux MC, Michelson KA, Landschaft A, Maulden AB, Chenard RL, Nigrovic LE. C-reactive protein or erythrocyte sedimentation rate results reliably exclude invasive bacterial infections. Am J Emerg Med. 2019 Aug; 37(8):1510-1515. View abstract
  18. Boyle TP, Kimia AA, Nigrovic LE. Validating a Clinical Prediction Rule for Ventricular Shunt Malfunction. Pediatr Emerg Care. 2018 Nov; 34(11):751-756. View abstract
  19. Hess EP, Homme JL, Kharbanda AB, Tzimenatos L, Louie JP, Cohen DM, Nigrovic LE, Westphal JJ, Shah ND, Inselman J, Ferrara MJ, Herrin J, Montori VM, Kuppermann N. Effect of the Head Computed Tomography Choice Decision Aid in Parents of Children With Minor Head Trauma: A Cluster Randomized Trial. JAMA Netw Open. 2018 Sep 07; 1(5):e182430. View abstract
  20. Hirsch AW, Popovsky EY, Nigrovic LE, Burns MM. A Brush with Danger. Clin Pract Cases Emerg Med. 2018 Nov; 2(4):373-374. View abstract
  21. Aronson PL, Wang ME, Nigrovic LE, Shah SS, Desai S, Pruitt CM, Balamuth F, Sartori L, Marble RD, Rooholamini SN, Leazer RC, Woll C, DePorre AG, Neuman MI. Time to Pathogen Detection for Non-ill Versus Ill-Appearing Infants =60 Days Old With Bacteremia and Meningitis. Hosp Pediatr. 2018 Jul; 8(7):379-384. View abstract
  22. Sundberg M, Perron CO, Kimia A, Landschaft A, Nigrovic LE, Nelson KA, Fine AM, Eisenberg M, Baskin MN, Neuman MI, Stack AM. A method to identify pediatric high-risk diagnoses missed in the emergency department. Diagnosis (Berl). 2018 Jun 27; 5(2):63-69. View abstract
  23. Kuppermann N, Ghetti S, Schunk JE, Stoner MJ, Rewers A, McManemy JK, Myers SR, Nigrovic LE, Garro A, Brown KM, Quayle KS, Trainor JL, Tzimenatos L, Bennett JE, DePiero AD, Kwok MY, Perry CS, Olsen CS, Casper TC, Dean JM, Glaser NS. Clinical Trial of Fluid Infusion Rates for Pediatric Diabetic Ketoacidosis. N Engl J Med. 2018 Jun 14; 378(24):2275-2287. View abstract
  24. Lyons TW, Cruz AT, Freedman SB, Nigrovic LE. Accuracy of Herpes Simplex Virus Polymerase Chain Reaction Testing of the Blood for Central Nervous System Herpes Simplex Virus Infections in Infants. J Pediatr. 2018 09; 200:274-276.e1. View abstract
  25. Woll C, Neuman MI, Pruitt CM, Wang ME, Shapiro ED, Shah SS, McCulloh RJ, Nigrovic LE, Desai S, DePorre AG, Leazer RC, Marble RD, Balamuth F, Feldman EA, Sartori LF, Browning WL, Aronson PL. Epidemiology and Etiology of Invasive Bacterial Infection in Infants =60 Days Old Treated in Emergency Departments. J Pediatr. 2018 09; 200:210-217.e1. View abstract
  26. Garro A, Koster M, LaRue M, Hipolito E, Congdon E, Burnett K, Cullen N, Nigrovic LE. Would Parents Consent to a Comparative Effectiveness Trial of Oral Doxycycline Versus Intravenous Ceftriaxone for the Treatment of Children with Lyme Meningitis? Pediatr Infect Dis J. 2018 05; 37(5):e140-e142. View abstract
  27. Dart AH, Michelson KA, Aronson PL, Garro AC, Lee TJ, Glerum KM, Nigrovic PA, Kocher MS, Bachur RG, Nigrovic LE. Hip Synovial Fluid Cell Counts in Children From a Lyme Disease Endemic Area. Pediatrics. 2018 05; 141(5). View abstract
  28. Adams CM, Nigrovic LE, Hayes G, Weinstock PH, Nagler J. Teaching Incision and Drainage: Perceived Educational Value of Abscess Models. Pediatr Emerg Care. 2018 Mar; 34(3):174-178. View abstract
  29. Wormser GP, Molins CR, Levin A, Lipsett SC, Nigrovic LE, Schriefer ME, Branda JA. Evaluation of a sequential enzyme immunoassay testing algorithm for Lyme disease demonstrates lack of test independence but high diagnostic specificity. Diagn Microbiol Infect Dis. 2018 Jul; 91(3):217-219. View abstract
  30. Thomson J, Sucharew H, Cruz AT, Nigrovic LE, Freedman SB, Garro AC, Balamuth F, Mistry RD, Arms JL, Ishimine PT, Kulik DM, Neuman MI, Shah SS. Cerebrospinal Fluid Reference Values for Young Infants Undergoing Lumbar Puncture. Pediatrics. 2018 03; 141(3). View abstract
  31. Cruz AT, Freedman SB, Kulik DM, Okada PJ, Fleming AH, Mistry RD, Thomson JE, Schnadower D, Arms JL, Mahajan P, Garro AC, Pruitt CM, Balamuth F, Uspal NG, Aronson PL, Lyons TW, Thompson AD, Curtis SJ, Ishimine PT, Schmidt SM, Bradin SA, Grether-Jones KL, Miller AS, Louie J, Shah SS, Nigrovic LE. Herpes Simplex Virus Infection in Infants Undergoing Meningitis Evaluation. Pediatrics. 2018 02; 141(2). View abstract
  32. Marcin JP, Romano PS, Dayal P, Dharmar M, Chamberlain JM, Dudley N, Macias CG, Nigrovic LE, Powell EC, Rogers AJ, Sonnett M, Tzimenatos L, Alpern ER, Andrews-Dickert R, Borgialli DA, Sidney E, Charles Casper T, Michael Dean J, Kuppermann N. Patient-level Factors and the Quality of Care Delivered in Pediatric Emergency Departments. Acad Emerg Med. 2018 03; 25(3):301-309. View abstract
  33. Nigrovic LE, Bennett JE, Balamuth F, Levas MN, Chenard RL, Maulden AB, Garro AC. Accuracy of Clinician Suspicion of Lyme Disease in the Emergency Department. Pediatrics. 2017 Dec; 140(6). View abstract
  34. Bressan S, Marchetto L, Lyons TW, Monuteaux MC, Freedman SB, Da Dalt L, Nigrovic LE. A Systematic Review and Meta-Analysis of the Management and Outcomes of Isolated Skull Fractures in Children. Ann Emerg Med. 2018 06; 71(6):714-724.e2. View abstract
  35. Marcin JP, Romano PS, Dharmar M, Chamberlain JM, Dudley N, Macias CG, Nigrovic LE, Powell EC, Rogers AJ, Sonnett M, Tzimenatos L, Alpern ER, Andrews-Dickert R, Borgialli DA, Sidney E, Casper C, Dean JM, Kuppermann N. Implicit Review Instrument to Evaluate Quality of Care Delivered by Physicians to Children in Emergency Departments. Health Serv Res. 2018 06; 53(3):1316-1334. View abstract
  36. Cruz AT, Mahajan P, Bonsu BK, Bennett JE, Levine DA, Alpern ER, Nigrovic LE, Atabaki SM, Cohen DM, VanBuren JM, Ramilo O, Kuppermann N. Accuracy of Complete Blood Cell Counts to Identify Febrile Infants 60 Days or Younger With Invasive Bacterial Infections. JAMA Pediatr. 2017 11 06; 171(11):e172927. View abstract
  37. Garro A, Nigrovic LE. Managing Peripheral Facial Palsy. Ann Emerg Med. 2018 May; 71(5):618-624. View abstract
  38. Green-Hopkins I, Monuteaux MC, Lee L, Nigrovic L, Mannix R, Schutzman S. Use of Ondansetron for Vomiting After Head Trauma: Does It Mask Clinically Significant Traumatic Brain Injury? Pediatr Emerg Care. 2017 Oct 16. View abstract
  39. Taylor AM, Nigrovic LE, Saillant ML, Trudell EK, Modest JR, Kuhn M, Vernacchio L. Educational Initiative to Standardize Concussion Management in Pediatric Primary Care. Clin Pediatr (Phila). 2018 Jun; 57(7):806-814. View abstract
  40. Lyons TW, Cruz AT, Freedman SB, Arms JL, Aronson PL, Fleming AH, Kulik DM, Mahajan P, Mistry RD, Pruitt CM, Thompson AD, Nigrovic LE. Correction of Cerebrospinal Fluid Protein in Infants With Traumatic Lumbar Punctures. Pediatr Infect Dis J. 2017 Oct; 36(10):1006-1008. View abstract
  41. Kessler DO, Nigrovic LE. X Marks the Spot (or Does It?): Ultrasonography-Assisted Site Marking for Lumbar Puncture in Children: Answers to the May 2017 Journal Club Questions. Ann Emerg Med. 2017 Oct; 70(4):592-596. View abstract
  42. Thomson J, Cruz AT, Nigrovic LE, Freedman SB, Garro AC, Ishimine PT, Kulik DM, Uspal NG, Grether-Jones KL, Miller AS, Schnadower D, Shah SS, Aronson PL, Balamuth F. Concomitant Bacterial Meningitis in Infants With Urinary Tract Infection. Pediatr Infect Dis J. 2017 09; 36(9):908-910. View abstract
  43. Michelson KA, Lyons TW, Johnson KB, Nigrovic LE, Harper MB, Kimia AA. Utility of Lumbar Puncture in Children Presenting With Status Epilepticus. Pediatr Emerg Care. 2017 Aug; 33(8):544-547. View abstract
  44. Feldman EA, McCulloh RJ, Myers AL, Aronson PL, Neuman MI, Bradford MC, Alpern ER, Balamuth F, Blackstone MM, Browning WL, Hayes K, Korman R, Leazer RC, Nigrovic LE, Marble R, Roben E, Williams DJ, Tieder JS. Empiric Antibiotic Use and Susceptibility in Infants With Bacterial Infections: A Multicenter Retrospective Cohort Study. Hosp Pediatr. 2017 Jul 20. View abstract
  45. Aronson PL, Lyons TW, Cruz AT, Freedman SB, Okada PJ, Fleming AH, Arms JL, Thompson AD, Schmidt SM, Louie J, Alfonzo MJ, Monuteaux MC, Nigrovic LE. Impact of Enteroviral Polymerase Chain Reaction Testing on Length of Stay for Infants 60 Days Old or Younger. J Pediatr. 2017 10; 189:169-174.e2. View abstract
  46. Nigrovic LE, Mahajan PV, Blumberg SM, Browne LR, Linakis JG, Ruddy RM, Bennett JE, Rogers AJ, Tzimenatos L, Powell EC, Alpern ER, Casper TC, Ramilo O, Kuppermann N. The Yale Observation Scale Score and the Risk of Serious Bacterial Infections in Febrile Infants. Pediatrics. 2017 Jun 06. View abstract
  47. Nigrovic LE, Mahajan PV, Blumberg SM, Browne LR, Linakis JG, Ruddy RM, Bennett JE, Rogers AJ, Tzimenatos L, Powell EC, Alpern ER, Casper TC, Ramilo O, Kuppermann N. The Yale Observation Scale Score and the Risk of Serious Bacterial Infections in Febrile Infants. Pediatrics. 2017 Jul; 140(1). View abstract
  48. Paydar-Darian N, Kimia AA, Lantos PM, Fine AM, Gordon CD, Gordon CR, Landschaft A, Nigrovic LE. Diagnostic Lumbar Puncture Among Children With Facial Palsy in a Lyme Disease Endemic Area. J Pediatric Infect Dis Soc. 2017 Jun 01; 6(2):205-208. View abstract
  49. Kessler DO, Nigrovic LE. X Marks the Spot (or Does It?): Ultrasonography-Assisted Site Marking for Lumbar Puncture in Children: May 2017 Annals of Emergency Medicine Journal Club. Ann Emerg Med. 2017 May; 69(5):657-658. View abstract
  50. Stanley RM, Nigrovic LE. Research priorities for a multi-center child abuse network: Lessons learned from pediatric emergency medicine networks. Child Abuse Negl. 2017 08; 70:414-416. View abstract
  51. Branda JA, Strle K, Nigrovic LE, Lantos PM, Lepore TJ, Damle NS, Ferraro MJ, Steere AC. Evaluation of Modified 2-Tiered Serodiagnostic Testing Algorithms for Early Lyme Disease. Clin Infect Dis. 2017 04 15; 64(8):1074-1080. View abstract
  52. Hudgins JD, Monuteaux MC, Bourgeois FT, Nigrovic LE, Fine AM, Lee LK, Mannix R, Lipsett SC, Neuman MI. Complexity and Severity of Pediatric Patients Treated at United States Emergency Departments. J Pediatr. 2017 07; 186:145-149.e1. View abstract
  53. Michelson KA, Nigrovic LE, Nagler J, McAneney CM, Mistry RD. Research Interest in Pediatric Emergency Medicine Fellows. Pediatr Emerg Care. 2017 Mar 13. View abstract
  54. Lantos PM, Tsao J, Nigrovic LE, Auwaerter PG, Fowler VG, Ruffin F, Foster E, Hickling G. Geographic Expansion of Lyme Disease in Michigan, 2000-2014. Open Forum Infect Dis. 2017; 4(1):ofw269. View abstract
  55. Lyons TW, Cruz AT, Freedman SB, Neuman MI, Balamuth F, Mistry RD, Mahajan P, Aronson PL, Thomson JE, Pruitt CM, Shah SS, Nigrovic LE. Interpretation of Cerebrospinal Fluid White Blood Cell Counts in Young Infants With a Traumatic Lumbar Puncture. Ann Emerg Med. 2017 May; 69(5):622-631. View abstract
  56. Mahajan P, Kuppermann N, Mejias A, Suarez N, Chaussabel D, Casper TC, Smith B, Alpern ER, Anders J, Atabaki SM, Bennett JE, Blumberg S, Bonsu B, Borgialli D, Brayer A, Browne L, Cohen DM, Crain EF, Cruz AT, Dayan PS, Gattu R, Greenberg R, Hoyle JD, Jaffe DM, Levine DA, Lillis K, Linakis JG, Muenzer J, Nigrovic LE, Powell EC, Rogers AJ, Roosevelt G, Ruddy RM, Saunders M, Tunik MG, Tzimenatos L, Vitale M, Dean JM, Ramilo O. Association of RNA Biosignatures With Bacterial Infections in Febrile Infants Aged 60 Days or Younger. JAMA. 2016 Aug 23-30; 316(8):846-57. View abstract
  57. Lipsett SC, Branda JA, McAdam AJ, Vernacchio L, Gordon CD, Gordon CR, Nigrovic LE. Evaluation of the C6 Lyme Enzyme Immunoassay for the Diagnosis of Lyme Disease in Children and Adolescents. Clin Infect Dis. 2016 10 01; 63(7):922-8. View abstract
  58. Lipsett SC, Nigrovic LE. Diagnosis of Lyme disease in the pediatric acute care setting. Curr Opin Pediatr. 2016 06; 28(3):287-93. View abstract
  59. Lyons TW, Stack AM, Monuteaux MC, Parver SL, Gordon CR, Gordon CD, Proctor MR, Nigrovic LE. A QI Initiative to Reduce Hospitalization for Children With Isolated Skull Fractures. Pediatrics. 2016 06; 137(6). View abstract
  60. Lantos PM, Lipsett SC, Nigrovic LE. False Positive Lyme Disease IgM Immunoblots in Children. J Pediatr. 2016 Jul; 174:267-269.e1. View abstract
  61. Moorthy LN, Muscal E, Riebschleger M, Klein-Gitelman M, Nigrovic LE, Horon JR, Rouster-Stevens K, Ferguson PJ, Eberhard BA, Brunner HI, Prahalad S, Schneider R, Nigrovic PA. Efficacy of an Interinstitutional Mentoring Program Within Pediatric Rheumatology. Arthritis Care Res (Hoboken). 2016 05; 68(5):645-51. View abstract
  62. McArthur R, Edlow JA, Nigrovic LE. Validation of the bacterial meningitis score in adults presenting to the ED with meningitis. Am J Emerg Med. 2016 Jul; 34(7):1265-7. View abstract
  63. Lyons TW, Johnson KB, Michelson KA, Nigrovic LE, Loddenkemper T, Prabhu SP, Kimia AA. Yield of emergent neuroimaging in children with new-onset seizure and status epilepticus. Seizure. 2016 Feb; 35:4-10. View abstract
  64. Lipsett SC, Pollock NR, Branda JA, Gordon CD, Gordon CR, Lantos PM, Nigrovic LE. The Positive Predictive Value of Lyme Elisa for the Diagnosis of Lyme Disease in Children. Pediatr Infect Dis J. 2015 Nov; 34(11):1260-2. View abstract
  65. Schonfeld D, Bressan S, Da Dalt L, Henien MN, Winnett JA, Nigrovic LE. Pediatric Emergency Care Applied Research Network head injury clinical prediction rules are reliable in practice. Postgrad Med J. 2015 Nov; 91(1081):634-8. View abstract
  66. Lantos PM, Nigrovic LE, Auwaerter PG, Fowler VG, Ruffin F, Brinkerhoff RJ, Reber J, Williams C, Broyhill J, Pan WK, Gaines DN. Geographic Expansion of Lyme Disease in the Southeastern United States, 2000-2014. Open Forum Infect Dis. 2015 Dec; 2(4):ofv143. View abstract
  67. Aronson PL, Williams DJ, Thurm C, Tieder JS, Alpern ER, Nigrovic LE, Schondelmeyer AC, Balamuth F, Myers AL, McCulloh RJ, Alessandrini EA, Shah SS, Browning WL, Hayes KL, Feldman EA, Neuman MI. Accuracy of diagnosis codes to identify febrile young infants using administrative data. J Hosp Med. 2015 Dec; 10(12):787-93. View abstract
  68. Lee LK, Monuteaux MC, Burghardt LC, Fleegler EW, Nigrovic LE, Meehan WP, Schutzman SA, Mannix R. Motor Vehicle Crash Fatalities in States With Primary Versus Secondary Seat Belt Laws: A Time-Series Analysis. Ann Intern Med. 2015 Aug 04; 163(3):184-90. View abstract
  69. Lantos PM, Branda JA, Boggan JC, Chudgar SM, Wilson EA, Ruffin F, Fowler V, Auwaerter PG, Nigrovic LE. Poor Positive Predictive Value of Lyme Disease Serologic Testing in an Area of Low Disease Incidence. Clin Infect Dis. 2015 Nov 01; 61(9):1374-80. View abstract
  70. Nigrovic LE, Stack AM, Mannix RC, Lyons TW, Samnaliev M, Bachur RG, Proctor MR. Quality Improvement Effort to Reduce Cranial CTs for Children With Minor Blunt Head Trauma. Pediatrics. 2015 Jul; 136(1):e227-33. View abstract
  71. Taylor AM, Nigrovic LE, Saillant ML, Trudell EK, Proctor MR, Modest JR, Vernacchio L. Trends in Ambulatory Care for Children with Concussion and Minor Head Injury from Eastern Massachusetts between 2007 and 2013. J Pediatr. 2015 Sep; 167(3):738-44. View abstract
  72. Boyle TP, Nigrovic LE. Radiographic evaluation of pediatric cerebrospinal fluid shunt malfunction in the emergency setting. Pediatr Emerg Care. 2015 Jun; 31(6):435-40; quiz 441-3. View abstract
  73. Aronson PL, Thurm C, Williams DJ, Nigrovic LE, Alpern ER, Tieder JS, Shah SS, McCulloh RJ, Balamuth F, Schondelmeyer AC, Alessandrini EA, Browning WL, Myers AL, Neuman MI. Association of clinical practice guidelines with emergency department management of febrile infants =56 days of age. J Hosp Med. 2015 Jun; 10(6):358-65. View abstract
  74. Pingree EW, Kimia AA, Nigrovic LE. The effect of traumatic lumbar puncture on hospitalization rate for febrile infants 28 to 60 days of age. Acad Emerg Med. 2015 Feb; 22(2):240-3. View abstract
  75. Rudloe T, Prabhu SP, Gorman MP, Nigrovic LE, Harper MB, Landschaft A, Kimia AA. The Yield of Neuroimaging in Children Presenting to the Emergency Department With Acute Ataxia in the Post-Varicella Vaccine Era. J Child Neurol. 2015 Sep; 30(10):1333-9. View abstract
  76. Green SM, Nigrovic LE, Krauss BS. Sick kids look sick. Ann Emerg Med. 2015 Jun; 65(6):633-5. View abstract
  77. Aronson PL, Thurm C, Alpern ER, Alessandrini EA, Williams DJ, Shah SS, Nigrovic LE, McCulloh RJ, Schondelmeyer A, Tieder JS, Neuman MI. Variation in care of the febrile young infant <90 days in US pediatric emergency departments. Pediatrics. 2014 Oct; 134(4):667-77. View abstract
  78. Boyle TP, Paldino MJ, Kimia AA, Fitz BM, Madsen JR, Monuteaux MC, Nigrovic LE. Comparison of rapid cranial MRI to CT for ventricular shunt malfunction. Pediatrics. 2014 Jul; 134(1):e47-54. View abstract
  79. Kuppermann N, Natale JE, Nigrovic LE. Incorrect classification in articles about traumatic brain injuries in children with minor blunt head trauma. JAMA Pediatr. 2014 Jun; 168(6):585-6. View abstract
  80. Johnson KB, Michelson KA, Lyons TW, Nigrovic LE, Landschaft A, Loddenkemper T, Kimia AA. Pediatric status epilepticus: how common is cerebrospinal fluid pleocytosis in the absence of infection? Seizure. 2014 Aug; 23(7):573-5. View abstract
  81. Mekitarian Filho E, Horita SM, Gilio AE, Nigrovic LE. Cerebrospinal fluid lactate level as a diagnostic biomarker for bacterial meningitis in children. Int J Emerg Med. 2014 Feb 27; 7(1):14. View abstract
  82. Schonfeld D, Bressan S, Da Dalt L, Henien MN, Winnett JA, Nigrovic LE. Pediatric Emergency Care Applied Research Network head injury clinical prediction rules are reliable in practice. Arch Dis Child. 2014 May; 99(5):427-31. View abstract
  83. Deanehan JK, Nigrovic PA, Milewski MD, Tan Tanny SP, Kimia AA, Smith BG, Nigrovic LE. Synovial fluid findings in children with knee monoarthritis in lyme disease endemic areas. Pediatr Emerg Care. 2014 Jan; 30(1):16-9. View abstract
  84. Mahajan P, Jaffe DM, Olsen CS, Leonard JR, Nigrovic LE, Rogers AJ, Kuppermann N, Leonard JC. Spinal cord injury without radiologic abnormality in children imaged with magnetic resonance imaging. J Trauma Acute Care Surg. 2013 Nov; 75(5):843-7. View abstract
  85. Lerner EB, Dayan PS, Brown K, Fuchs S, Leonard J, Borgialli D, Babcock L, Hoyle JD, Kwok M, Lillis K, Nigrovic LE, Mahajan P, Rogers A, Schwartz H, Soprano J, Tsarouhas N, Turnipseed S, Funai T, Foltin G. Characteristics of the pediatric patients treated by the Pediatric Emergency Care Applied Research Network's affiliated EMS agencies. Prehosp Emerg Care. 2014 Jan-Mar; 18(1):52-9. View abstract
  86. Walsh KE, Cutrona SL, Foy S, Baker MA, Forrow S, Shoaibi A, Pawloski PA, Conroy M, Fine AM, Nigrovic LE, Selvam N, Selvan MS, Cooper WO, Andrade S. Validation of anaphylaxis in the Food and Drug Administration's Mini-Sentinel. Pharmacoepidemiol Drug Saf. 2013 Nov; 22(11):1205-13. View abstract
  87. Mekitarian Filho E, Horita SM, Gilio AE, Alves AC, Nigrovic LE. The bacterial meningitis score to distinguish bacterial from aseptic meningitis in children from Sao Paulo, Brazil. Pediatr Infect Dis J. 2013 Sep; 32(9):1026-9. View abstract
  88. Nigrovic LE, Schonfeld D, Dayan PS, Fitz BM, Mitchell SR, Kuppermann N. Nurse and physician agreement in the assessment of minor blunt head trauma. Pediatrics. 2013 Sep; 132(3):e689-94. View abstract
  89. Schonfeld D, Fitz BM, Nigrovic LE. Effect of the duration of emergency department observation on computed tomography use in children with minor blunt head trauma. Ann Emerg Med. 2013 Dec; 62(6):597-603. View abstract
  90. Sheehan B, Nigrovic LE, Dayan PS, Kuppermann N, Ballard DW, Alessandrini E, Bajaj L, Goldberg H, Hoffman J, Offerman SR, Mark DG, Swietlik M, Tham E, Tzimenatos L, Vinson DR, Jones GS, Bakken S. Informing the design of clinical decision support services for evaluation of children with minor blunt head trauma in the emergency department: a sociotechnical analysis. J Biomed Inform. 2013 Oct; 46(5):905-13. View abstract
  91. Gibson S, Nigrovic LE, O'Brien M, Meehan WP. The effect of recommending cognitive rest on recovery from sport-related concussion. Brain Inj. 2013; 27(7-8):839-42. View abstract
  92. Mannix R, Monuteaux MC, Schutzman SA, Meehan WP, Nigrovic LE, Neuman MI. Isolated skull fractures: trends in management in US pediatric emergency departments. Ann Emerg Med. 2013 Oct; 62(4):327-31. View abstract
  93. Nigrovic LE, Cohn KA, Lyons TW, Thompson AD, Hines EM, Welsh EJ, Shah SS. Enteroviral testing and length of hospital stay for children evaluated for lyme meningitis. J Emerg Med. 2013 Jun; 44(6):1196-200. View abstract
  94. Nigrovic LE, Fine AM, Monuteaux MC, Shah SS, Neuman MI. Trends in the management of viral meningitis at United States children's hospitals. Pediatrics. 2013 Apr; 131(4):670-6. View abstract
  95. Deanehan JK, Kimia AA, Tan Tanny SP, Milewski MD, Talusan PG, Smith BG, Nigrovic LE. Distinguishing Lyme from septic knee monoarthritis in Lyme disease-endemic areas. Pediatrics. 2013 Mar; 131(3):e695-701. View abstract
  96. Nigrovic LE. Aseptic meningitis. Handb Clin Neurol. 2013; 112:1153-6. View abstract
  97. Mannix R, Fleegler E, Meehan WP, Schutzman SA, Hennelly K, Nigrovic L, Lee LK. Booster seat laws and fatalities in children 4 to 7 years of age. Pediatrics. 2012 Dec; 130(6):996-1002. View abstract
  98. Nigrovic LE, Lillis K, Atabaki SM, Dayan PS, Hoyle J, Tunik MG, Jacobs ES, Monroe D, Wootton-Gorges SW, Miskin M, Holmes JF, Kuppermann N. The prevalence of traumatic brain injuries after minor blunt head trauma in children with ventricular shunts. Ann Emerg Med. 2013 Apr; 61(4):389-93. View abstract
  99. Thompson AD, Cohn KA, Shah SS, Lyons T, Welsh EJ, Hines EM, Nigrovic LE. Treatment complications in children with lyme meningitis. Pediatr Infect Dis J. 2012 Oct; 31(10):1032-5. View abstract
  100. Hennelly KE, Mannix R, Nigrovic LE, Lee LK, Thompson KM, Monuteaux MC, Proctor M, Schutzman S. Pediatric traumatic brain injury and radiation risks: a clinical decision analysis. J Pediatr. 2013 Feb; 162(2):392-7. View abstract
  101. Welsh EJ, Cohn KA, Nigrovic LE, Thompson AD, Hines EM, Lyons TW, Glatz AC, Shah SS. Electrocardiograph Abnormalities in Children With Lyme Meningitis. J Pediatric Infect Dis Soc. 2012 Dec; 1(4):293-8. View abstract
  102. Nigrovic LE, Malley R, Kuppermann N. Meta-analysis of bacterial meningitis score validation studies. Arch Dis Child. 2012 Sep; 97(9):799-805. View abstract
  103. Lyons TW, McAdam AJ, Cohn KA, Monuteaux MC, Nigrovic LE. Impact of in-hospital enteroviral polymerase chain reaction testing on the clinical management of children with meningitis. J Hosp Med. 2012 Sep; 7(7):517-20. View abstract
  104. Rogers EA, Kimia A, Madsen JR, Nigrovic LE, Neuman MI. Predictors of ventricular shunt infection among children presenting to a pediatric emergency department. Pediatr Emerg Care. 2012 May; 28(5):405-9. View abstract
  105. Nigrovic LE, Rogers AJ, Adelgais KM, Olsen CS, Leonard JR, Jaffe DM, Leonard JC. Utility of plain radiographs in detecting traumatic injuries of the cervical spine in children. Pediatr Emerg Care. 2012 May; 28(5):426-32. View abstract
  106. Bargui F, D'Agostino I, Mariani-Kurkdjian P, Alberti C, Doit C, Bellier N, Morin L, Galli Gibertini G, Smail A, Zanin A, Lorrot M, Dauger S, Neve M, Faye A, Armoogum P, Bourrillon A, Bingen E, Mercier JC, Bonacorsi S, Nigrovic LE, Titomanlio L. Factors influencing neurological outcome of children with bacterial meningitis at the emergency department. Eur J Pediatr. 2012 Sep; 171(9):1365-71. View abstract
  107. Kerrey BT, Rinderknecht AS, Geis GL, Nigrovic LE, Mittiga MR. Rapid sequence intubation for pediatric emergency patients: higher frequency of failed attempts and adverse effects found by video review. Ann Emerg Med. 2012 Sep; 60(3):251-9. View abstract
  108. Hines EM, Nigrovic LE, Neuman MI, Shah SS. Adjustment of cerebrospinal fluid protein for red blood cells in neonates and young infants. J Hosp Med. 2012 Apr; 7(4):325-8. View abstract
  109. Nigrovic LE, Kimia AA, Shah SS, Neuman MI. Relationship between cerebrospinal fluid glucose and serum glucose. N Engl J Med. 2012 Feb 09; 366(6):576-8. View abstract
  110. Cohn KA, Thompson AD, Shah SS, Hines EM, Lyons TW, Welsh EJ, Nigrovic LE. Validation of a clinical prediction rule to distinguish Lyme meningitis from aseptic meningitis. Pediatrics. 2012 Jan; 129(1):e46-53. View abstract
  111. Nigrovic LE, Lee LK, Hoyle J, Stanley RM, Gorelick MH, Miskin M, Atabaki SM, Dayan PS, Holmes JF, Kuppermann N. Prevalence of clinically important traumatic brain injuries in children with minor blunt head trauma and isolated severe injury mechanisms. Arch Pediatr Adolesc Med. 2012 Apr; 166(4):356-61. View abstract
  112. Mannix R, Nigrovic LE, Schutzman SA, Hennelly K, Bourgeois FT, Meehan WP, Fleisher G, Monuteaux M, Lee LK. Factors associated with the use of cervical spine computed tomography imaging in pediatric trauma patients. Acad Emerg Med. 2011 Sep; 18(9):905-11. View abstract
  113. Nigrovic LE, Schunk JE, Foerster A, Cooper A, Miskin M, Atabaki SM, Hoyle J, Dayan PS, Holmes JF, Kuppermann N. The effect of observation on cranial computed tomography utilization for children after blunt head trauma. Pediatrics. 2011 Jun; 127(6):1067-73. View abstract
  114. Nigrovic LE, Shah SS, Neuman MI. Correction of cerebrospinal fluid protein for the presence of red blood cells in children with a traumatic lumbar puncture. J Pediatr. 2011 Jul; 159(1):158-9. View abstract
  115. Fine AM, Brownstein JS, Nigrovic LE, Kimia AA, Olson KL, Thompson AD, Mandl KD. Integrating spatial epidemiology into a decision model for evaluation of facial palsy in children. Arch Pediatr Adolesc Med. 2011 Jan; 165(1):61-7. View abstract
  116. Nigrovic LE, Malley R, Agrawal D, Kuppermann N. Low risk of bacterial meningitis in children with a positive enteroviral polymerase chain reaction test result. Clin Infect Dis. 2010 Nov 15; 51(10):1221-2. View abstract
  117. Leonard JC, Kuppermann N, Olsen C, Babcock-Cimpello L, Brown K, Mahajan P, Adelgais KM, Anders J, Borgialli D, Donoghue A, Hoyle JD, Kim E, Leonard JR, Lillis KA, Nigrovic LE, Powell EC, Rebella G, Reeves SD, Rogers AJ, Stankovic C, Teshome G, Jaffe DM. Factors associated with cervical spine injury in children after blunt trauma. Ann Emerg Med. 2011 Aug; 58(2):145-55. View abstract
  118. Fine AM, Reis BY, Nigrovic LE, Goldmann DA, Laporte TN, Olson KL, Mandl KD. Use of population health data to refine diagnostic decision-making for pertussis. J Am Med Inform Assoc. 2010 Jan-Feb; 17(1):85-90. View abstract
  119. Kanegaye JT, Nigrovic LE, Malley R, Cannavino CR, Schwab SH, Bennett JE, Mohseni MM, Wang VJ, Katsogridakis YL, Herman MI, Kuppermann N. Diagnostic value of immature neutrophils (bands) in the cerebrospinal fluid of children with cerebrospinal fluid pleocytosis. Pediatrics. 2009 Jun; 123(6):e967-71. View abstract
  120. Nigrovic LE, Malley R, Kuppermann N. Cerebrospinal fluid pleocytosis in children in the era of bacterial conjugate vaccines: distinguishing the child with bacterial and aseptic meningitis. Pediatr Emerg Care. 2009 Feb; 25(2):112-7; quiz 118-20. View abstract
  121. Nigrovic LE, Thompson AD, Fine AM, Kimia A. Clinical predictors of Lyme disease among children with a peripheral facial palsy at an emergency department in a Lyme disease-endemic area. Pediatrics. 2008 Nov; 122(5):e1080-5. View abstract
  122. Nigrovic LE, Malley R, Macias CG, Kanegaye JT, Moro-Sutherland DM, Schremmer RD, Schwab SH, Agrawal D, Mansour KM, Bennett JE, Katsogridakis YL, Mohseni MM, Bulloch B, Steele DW, Kaplan RL, Herman MI, Bandyopadhyay S, Dayan P, Truong UT, Wang VJ, Bonsu BK, Chapman JL, Kuppermann N. Effect of antibiotic pretreatment on cerebrospinal fluid profiles of children with bacterial meningitis. Pediatrics. 2008 Oct; 122(4):726-30. View abstract
  123. Nigrovic LE, Wingerter SL. Tularemia. Infect Dis Clin North Am. 2008 Sep; 22(3):489-504, ix. View abstract
  124. Nigrovic LE, Kuppermann N, Malley R. Children with bacterial meningitis presenting to the emergency department during the pneumococcal conjugate vaccine era. Acad Emerg Med. 2008 Jun; 15(6):522-8. View abstract
  125. Nigrovic LE, Trivedi M, Edlow JA, Neuman MI. Cerebrospinal fluid xanthochromia in newborns is related to maternal labor before delivery. Pediatrics. 2007 Nov; 120(5):e1212-6. View abstract
  126. Nigrovic LE, McQueen AA, Neuman MI. Lumbar puncture success rate is not influenced by family-member presence. Pediatrics. 2007 Oct; 120(4):e777-82. View abstract
  127. Nigrovic LE, Kuppermann N, Malley R. Letter in response. Clinical decision rule to identify patients at very low risk of bacterial meningitis. JAMA. 2007; 297(15):1653-1655. View abstract
  128. Nigrovic LE, Kuppermann N, Neuman MI. Risk factors for traumatic or unsuccessful lumbar punctures in children. Ann Emerg Med. 2007 Jun; 49(6):762-71. View abstract
  129. Fine AM, Nigrovic LE, Reis BY, Cook EF, Mandl KD. Linking surveillance to action: incorporation of real-time regional data into a medical decision rule. J Am Med Inform Assoc. 2007 Mar-Apr; 14(2):206-11. View abstract
  130. Nigrovic LE, Kuppermann N, Macias CG, Cannavino CR, Moro-Sutherland DM, Schremmer RD, Schwab SH, Agrawal D, Mansour KM, Bennett JE, Katsogridakis YL, Mohseni MM, Bulloch B, Steele DW, Kaplan RL, Herman MI, Bandyopadhyay S, Dayan P, Truong UT, Wang VJ, Bonsu BK, Chapman JL, Kanegaye JT, Malley R. Clinical prediction rule for identifying children with cerebrospinal fluid pleocytosis at very low risk of bacterial meningitis. JAMA. 2007 Jan 03; 297(1):52-60. View abstract
  131. Stoll ML, Zurakowski D, Nigrovic LE, Nichols DP, Sundel RP, Nigrovic PA. Patients with juvenile psoriatic arthritis comprise two distinct populations. Arthritis Rheum. 2006 Nov; 54(11):3564-72. View abstract
  132. Nigrovic LE, Thompson KM. The Lyme vaccine: a cautionary tale. Epidemiol Infect. 2007 Jan; 135(1):1-8. View abstract
  133. Nigrovic LE, Nigrovic PA, Harper MB, Chiang VW. Extreme thrombocytosis predicts Kawasaki disease in infants. Clin Pediatr (Phila). 2006 Jun; 45(5):446-52. View abstract
  134. Nigrovic LE, Kuppermann N, McAdam AJ, Malley R. Cerebrospinal latex agglutination fails to contribute to the microbiologic diagnosis of pretreated children with meningitis. Pediatr Infect Dis J. 2004 Aug; 23(8):786-8. View abstract
  135. Nigrovic LE, Malley R. Evaluation of the febrile child 3 to 36 months old in the era of the pneumococcal conjugate vaccine: focus on occult bacteremia. Clin Pediatr Emerg Med. 2004; 49:13-19. View abstract
  136. Nigrovic LE, Kuppermann N, Malley R. Development and validation of a multivariable predictive model to distinguish bacterial from aseptic meningitis in children in the post-Haemophilus influenzae era. Pediatrics. 2002 Oct; 110(4):712-9. View abstract
  137. Nigrovic LE, Lumeng C, Landrigan C, Chiang VW. Rotavirus cerebellitis? Clin Infect Dis. 2002 Jan 01; 34(1):130. View abstract
  138. Rehm KP, Nigrovic LE. Introduction. Curr Opin Pediatr. 2001 Feb; 13(1):81. View abstract
  139. Babl FE, Edelberg LH, Shannon M. Oral and airway sequelae after hair relaxer ingestion. Pediatr Emerg Care. 2001 Feb; 17(1):36-7. View abstract
  140. Nigrovic LE. What's new with enteroviral infections? Curr Opin Pediatr. 2001 Feb; 13(1):89-94. View abstract
  141. Nigrovic LE, Chiang VW. Cost analysis of enteroviral polymerase chain reaction in infants with fever and cerebrospinal fluid pleocytosis. Arch Pediatr Adolesc Med. 2000 Aug; 154(8):817-21. View abstract