Dan Nigrin MD, MS

Daniel Nigrin, MD, MS

SVP & Chief Information Officer; Assistant in Medicine

Assistant Professor of Pediatrics, Harvard Medical School

    Contact: 617-355-7476
  • Fax: 617-730-0019

Medical Services


  • Endocrinology
  • Medicine


  • Endocrinology Program
  • Diabetes Program
To schedule an appointment: Call 617-355-7476

Experience and Education


BA, Biophysics

Johns Hopkins University, 1987

Baltimore, MD

Fellowship, Pediatric Endocrinology

Boston Children's Hospital, 1995-1998

Boston, MA

MS, Medical Informatics

Massachusetts Institute of Technology, 1999

Boston, MA

Medical School

Johns Hopkins University School of Medicine, 1991

Baltimore, MD

Internship, Pediatrics

Johns Hopkins Hospital, 1992

Baltimore, MD

Residency, Pediatrics

Johns Hopkins Hospital, 1991-1994

Baltimore, MD


  • American Board of Pediatrics, Pediatric Endocrinology

  • American Board of Preventative Medicine, Clinical Informatics


Publications powered by Harvard Catalyst Profiles
  1. Twichell SA, Rea CJ, Melvin P, Capraro AJ, Mandel JC, Ferguson MA, Nigrin DJ, Mandl KD, Graham D, Zachariah JP. The effect of an electronic health record-based tool on abnormal pediatric blood pressure recognition. Congenit Heart Dis. 2017 Jul; 12(4):484-490.
  2. Bourgeois FC, Nigrin DJ, Harper MB. Preserving patient privacy and confidentiality in the era of personal health records. Pediatrics. 2015 May; 135(5):e1125-7.
  3. Nigrin DJ. When 'hacktivists' target your hospital. N Engl J Med. 2014 Jul 31; 371(5):393-5.
  4. Bourgeois FC, Mandl KD, Shaw D, Flemming D, Nigrin DJ. Mychildren's: integration of a personally controlled health record with a tethered patient portal for a pediatric and adolescent population. AMIA Annu Symp Proc. 2009 Nov 14; 2009:65-9.
  5. Weber GM, Murphy SN, McMurry AJ, Macfadden D, Nigrin DJ, Churchill SI, Kohane IS. The Shared Information Network (SHRINE): A prototype federated query tool for clinical data repositories. J Amer.Med. Inform. Assoc. 2009; 16(5):624-630.
  6. Weber GM, Murphy SN, McMurry AJ, Macfadden D, Nigrin DJ, Churchill S, Kohane IS. The Shared Health Research Information Network (SHRINE): a prototype federated query tool for clinical data repositories. J Am Med Inform Assoc. 2009 Sep-Oct; 16(5):624-30.
  7. Nigrin, DJ. Health IT for Kids, Pediatric Health IT and the Flu. Government Health IT. 2009; 3(5):3.
  8. Nigrin DJ. Pharmacy Automation, High Tech Tools Close the Loop for Medication Safety. Most Wired. 2009.
  9. Holm IA, Kohane IS, Mandl K, Clinton C, Adida B, Nigrin DJ, Taylor P, Kunkel LM. The Gene Partnership Project: Implementing the informed cohort model for the ethical recruitment and engagement of participant into genomic research. American Socity of Human Genetics . 2009.
  10. Bourgeois FC, Taylor PL, Emans SJ, Nigrin DJ, Mandl KD. Whose personal control? Creating private, personally controlled health records for pediatric and adolescent patients. J Am Med Inform Assoc. 2008 Nov-Dec; 15(6):737-43.
  11. Show all
  12. Nigrin, DJ. The Importance of Technology in Healthcare. Inside The Minds: Updating Your Company's Technology Strategy. 2008.
  13. Kohane IS, Mandl KD, Taylor PL, Holm IA, Nigrin DJ, Kunkel LM. Medicine. Reestablishing the researcher-patient compact. Science. 2007 May 11; 316(5826):836-7.
  14. Quinn M, Fleischman A, Rosner B, Nigrin DJ, Wolfsdorf JI. Characteristics at diagnosis of type 1 diabetes in children younger than 6 years. J Pediatr. 2006 Mar; 148(3):366-71.
  15. Simons WW, Halamka JD, Kohane IS, Nigrin D, Finstein N, Mandl KD. Integration of the personally controlled electronic medical record into regional inter-regional data exchanges: a national demonstration. AMIA Annu Symp Proc. 2006; 1099.
  16. Simons WW, Halamka JD, Kohane IS, Nigrin D, Finstein N, Mandl KD. Integration of the personally controlled electronic medical record into regional inter-regional data exchanges: a national demonstration. Proc AMIA Symp. 2006; 1099.
  17. Landrigan CP, Muret-Wagstaff S, Chiang VW, Nigrin DJ, Goldmann DA, Finkelstein JA. Senior resident autonomy in a pediatric hospitalist system. Arch Pediatr Adolesc Med. 2003 Feb; 157(2):206-7.
  18. Landrigan CP, Muret-Wagstaff S, Chiang VW, Nigrin DJ, Goldmann DA, Finkelstein JA. Effect of a pediatric hospitalist system on housestaff education and experience. Arch Pediatr Adolesc Med. 2002 Sep; 156(9):877-83.
  19. Riva A, Mandl KD, Oh DH, Nigrin DJ, Butte A, Szolovits P, Kohane IS. The personal internetworked notary and guardian. Int J Med Inform. 2001 Jun; 62(1):27-40.
  20. Rhee EK, Evangelista JK, Nigrin DJ, Erickson LC. Impact of anatomic closure on somatic growth among small, asymptomatic children with secundum atrial septal defect. Am J Cardiol. 2000 Jun 15; 85(12):1472-5.
  21. Nigrin DJ, Kohane IS. Temporal expressiveness in querying a time-stamp--based clinical database. J Am Med Inform Assoc. 2000 Mar-Apr; 7(2):152-63.
  22. Nigrin DJ, Kohane IS. Glucoweb: a case study of secure, remote biomonitoring and communication. Proc AMIA Symp. 2000; 610-4.
  23. Wolfsdorf JI, Nigrin DJ. Diabetes in Children. Cefalu WT, Clark NG, Leahy JL, editors. Medical Management of Diabetes Mellitus. 2000.
  24. Dodson BL, Lucich JL, Nigrin DJ. Evolution to a Palm Pilot based intervention tracking tool for clinical pharmacists in a pediatric teaching hospital. American Society of Health-System Pharmacists, Midyear Clinical Meeting. 2000.
  25. Nigrin DJ, Kohane IS, inventors. System and method for performing stepwise querying of a timestamp-based database. 1999.
  26. Nigrin DJ, Kohane IS. Scaling a data retrieval and mining application to the enterprise-wide level. Proc AMIA Symp. 1999; 901-5.
  27. Nigrin DJ, Kohane IS. A New tool for Improved Research Utilization of Pediatric Clinical Databases. Pediatr Res. 1999; 45.
  28. Nigrin DJ. Improved access to large medical databases for clinical research and quality improvement [dissertation]. 1999.
  29. Nigrin DJ, Kohane IS. Growth Calc: an antropometric calculator accessible via the World Wide Web. Soc Ped Research. 1999.
  30. Nigrin DJ, Kohane IS. Data mining by clinicians. Proc AMIA Symp. 1998; 957-61.
  31. Nigrin DJ. ATRAS: a decision support application layered on the W3-EMRS architecture. Stud Health Technol Inform. 1998; 52 Pt 1:40-4.
  32. Tsien CL, Nigrin DJ, Kohane IS. Methodology for computer-assisted prediction of growth hormone deficiency in children. Proc AMIA Symposium. 1998; 1088.
  33. Nigrin DJ. IT? Give me what I'll use. Healthc Inform. 1997 May; 14(5):112.
  34. Nigrin DJ. Implementation of Portable Decision Support Using the W-3 EMRS Architecture. Proc AMIA Symposium. 1997; (1997):879.
  35. Nigrin DJ, Kohane IS. ATRAS: A database-independent, computer-based retrieval and analysis system for functional adrenal hormone testing. Proc 79th Annual Meeting of the Endo Society. 1997.
  36. North RB, Nigrin DJ, Fowler KR, Szymanski RE, Piantadosi S. Automated 'pain drawing' analysis by computer-controlled, patient-interactive neurological stimulation system. Pain. 1992 Jul; 50(1):51-7.
  37. North RB, Fowler K, Nigrin DJ, Szymanski R. Patient-interactive, computer-controlled neurological stimulation system: clinical efficacy in spinal cord stimulator adjustment. J Neurosurg. 1992 Jun; 76(6):967-72.
To schedule an appointment: Call 617-355-7476


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