Michael McManus

Michael McManus, MD, MPH

Senior Associate in Critical Care Medicine, Boston Children’s Chair in Critical Care Anesthesiology

Associate Professor of Anaesthesia, Harvard Medical School.

  • Contact: 617-355-7327

  • Fax: 617-734-3863

Medical Services


  • Anesthesia
  • Critical Care


  • Critical Care Medicine
  • Anesthesiology Perioperative and Pain Medicine


  • Division of Perioperative Anesthesia
To schedule an appointment:

Experience and Education


Graduate School, MPH Policy & Management

Harvard School of Public Health, 2001

Boston, MA

Medical School

Northwestern University Medical School, 1983

Chicago, IL


Boston Children's Hospital, 1983-1984

Boston, MA

Residency, Pediatrics

Boston Children's Hospital, 1983-1986

Boston, MA

Residency, Anaesthesia

Massachusetts General Hospital, 1986-1988

Boston, MA

Fellowship, Pediatric Anesthesia Critical Care

Boston Children's Hospital, 1988-1989

Boston, MA


  • Anesthesiology, Pediatrics, Critical Care Medicine


Research Focus Area
Public health systems, access to care

For more information, please visit my research profile.


Publications powered by Harvard Catalyst Profiles
  1. McManus ML. Shifting Goals in Operating Room Management. A A Case Rep. 2016 Mar 15; 6(6):181-2.
  2. França UL, Mustafa S, McManus ML. The Growing Burden of Neonatal Opiate Exposure on Children and Family Services in Massachusetts. Child Maltreat. 2016 Feb; 21(1):80-4.
  3. Bravo F, Levi R, Ferrari LR, McManus ML. The nature and sources of variability in pediatric surgical case duration. Paediatr Anaesth. 2015 Oct; 25(10):999-1006.
  4. Casavant DW, McManus ML, Parsons SK, Zurakowski D, Graham RJ. Trial of telemedicine for patients on home ventilator support: feasibility, confidence in clinical management and use in medical decision-making. J Telemed Telecare. 2014 Dec; 20(8):441-9.
  5. Sturrock A, Seedahmed E, Mir-Kasimov M, Boltax J, McManus ML, Paine R. GM-CSF provides autocrine protection for murine alveolar epithelial cells from oxidant-induced mitochondrial injury. Am J Physiol Lung Cell Mol Physiol. 2012 Feb 1; 302(3):L343-51.
  6. Solter LF, Pilarska DK, McManus ML, Zúbrik M, Patocka J, Huang WF, Novotný J. Host specificity of microsporidia pathogenic to the gypsy moth, Lymantria dispar (L.): field studies in Slovakia. J Invertebr Pathol. 2010 Sep; 105(1):1-10.
  7. Hoch G, D'Amico V, Solter LF, Zubrik M, McManus ML. Quantifying horizontal transmission of Nosema lymantriae, a microsporidian pathogen of the gypsy moth, Lymantria dispar (Lep., Lymantriidae) in field cage studies. J Invertebr Pathol. 2008 Oct; 99(2):146-50.
  8. Vinecore K, Aboy M, McNames J, Phillips C, Agbeko R, Peters M, Ellenby M, McManus ML, Goldstein B. Design and implementation of a portable physiologic data acquisition system. Pediatr Crit Care Med. 2007 Nov; 8(6):563-9.
  9. Wolf GK, McClain CD, Zurakowski D, Dodson B, McManus ML. Total phenytoin concentrations do not accurately predict free phenytoin concentrations in critically ill children. Pediatr Crit Care Med. 2006 Sep; 7(5):434-9; quiz 440.
  10. Vavra J, Hylis M, Vossbrinck CR, Pilarska DK, Linde A, Weiser J, McManus ML, Hoch G, Solter LF. Vairimorpha disparis n. comb. (Microsporidia: Burenellidae): a redescription and taxonomic revision of Thelohania disparis Timofejeva 1956, a microsporidian parasite of the gypsy moth Lymantria dispar (L.) (Lepidoptera: Lymantriidae). J Eukaryot Microbiol. 2006 Jul-Aug; 53(4):292-304.
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  12. Fallon DJ, Solter LF, Bauer LS, Miller DL, Cate JR, McManus ML. Effect of entomopathogenic nematodes on Plectrodera scalator (Fabricius) (Coleoptera: Cerambycidae). J Invertebr Pathol. 2006 May; 92(1):55-7.
  13. Hylis M, Pilarska DK, Oborník M, Vávra J, Solter LF, Weiser J, Linde A, McManus ML. Nosema chrysorrhoeae n. sp. (Microsporidia), isolated from browntail moth (Euproctis chrysorrhoea L.) (Lepidoptera, Lymantriidae) in Bulgaria: characterization and phylogenetic relationships. J Invertebr Pathol. 2006 Feb; 91(2):105-14.
  14. Litvak E, Buerhaus PI, Davidoff F, Long MC, McManus ML, Berwick DM. Managing unnecessary variability in patient demand to reduce nursing stress and improve patient safety. Jt Comm J Qual Patient Saf. 2005 Jun; 31(6):330-8.
  15. Khwaja OS, Robson CD, McManus ML, Urion DK. Basilar meningitis associated with ethmoid and sphenoid cephaloceles. Pediatr Neurol. 2005 Jul; 33(1):57-60.
  16. Wise-Faberowski L, Soriano SG, Ferrari L, McManus ML, Wolfsdorf JI, Majzoub J, Scott RM, Truog R, Rockoff MA. Perioperative management of diabetes insipidus in children. J Neurosurg Anesthesiol. 2004 Jul; 16(3):220-5.
  17. McManus ML, Long MC, Cooper A, Litvak E. Queuing theory accurately models the need for critical care resources. Anesthesiology. 2004 May; 100(5):1271-6.
  18. Wise-Faberowski L, Soriano SG, Ferrari L, McManus ML, Wolfsdorf JI, Majzoub J, Scott RM, Truog R, Rockoff MA. Perioperative management of diabetes insipidus in children [corrected]. J Neurosurg Anesthesiol. 2004 Jan; 16(1):14-9.
  19. McManus ML, Long MC, Cooper A, Mandell J, Berwick DM, Pagano M, Litvak E. Variability in surgical caseload and access to intensive care services. Anesthesiology. 2003 Jun; 98(6):1491-6.
  20. Litvak E, Long MC, Cooper AB, McManus ML. Emergency department diversion: causes and solutions. Acad Emerg Med. 2001 Nov; 8(11):1108-10.
  21. D'Amico V, Elkinton JS, Podgwaite JD, Slavicek JM, McManus ML, Burand JP. A field release of genetically engineered gypsy moth (Lymantria dispar L.) nuclear polyhedrosis virus (LdNPV). J Invertebr Pathol. 1999 May; 73(3):260-8.
  22. Bauer LS, Miller DL, Maddox JV, McManus ML. Interactions between a Nosema sp. (Microspora: nosematidae) and nuclear polyhedrosis virus infecting the gypsy moth, Lymantria dispar (Lepidoptera: lymantriidae). J Invertebr Pathol. 1998 Sep; 72(2):147-53.
  23. McManus ML, Soriano SG. Rebound swelling of astroglial cells exposed to hypertonic mannitol. Anesthesiology. 1998 Jun; 88(6):1586-91.
  24. Emma F, McManus M, Strange K. Intracellular electrolytes regulate the volume set point of the organic osmolyte/anion channel VSOAC. Am J Physiol. 1997 Jun; 272(6 Pt 1):C1766-75.
  25. Soriano SG, McManus ML, Sullivan LJ, Rockoff MA, Black PM, Burrows FA. Cerebral blood flow velocity after mannitol infusion in children. Can J Anaesth. 1996 May; 43(5 Pt 1):461-6.
  26. McManus ML, Churchwell KB, Strange K. Regulation of cell volume in health and disease. N Engl J Med. 1995 Nov 9; 333(19):1260-6.
  27. McManus ML, Kevy SV, Bower LK, Hickey PR. Coagulation factor deficiencies during initiation of extracorporeal membrane oxygenation. J Pediatr. 1995 Jun; 126(6):900-4.
  28. Churchwell KB, McManus ML, Kent P, Gorlin J, Galacki D, Humphreys D, Kevy SV. Intensive blood and plasma exchange for treatment of coagulopathy in meningococcemia. J Clin Apher. 1995; 10(4):171-7.
  29. Soriano SG, McManus ML, Sullivan LJ, Scott RM, Rockoff MA. Doppler sensor placement during neurosurgical procedures for children in the prone position. J Neurosurg Anesthesiol. 1994 Jul; 6(3):153-5.
  30. McManus M, Serhan C, Jackson P, Strange K. Ketoconazole blocks organic osmolyte efflux independently of its effect on arachidonic acid conversion. Am J Physiol. 1994 Jul; 267(1 Pt 1):C266-71.
  31. McManus M, Fischbarg J, Sun A, Hebert S, Strange K. Laser light-scattering system for studying cell volume regulation and membrane transport processes. Am J Physiol. 1993 Aug; 265(2 Pt 1):C562-70.
  32. McManus ML, Strange K. Acute volume regulation of brain cells in response to hypertonic challenge. Anesthesiology. 1993 Jun; 78(6):1132-7.
  33. McManus ML, Churchwell KB. Coagulopathy as a predictor of outcome in meningococcal sepsis and the systemic inflammatory response syndrome with purpura. Crit Care Med. 1993 May; 21(5):706-11.
  34. Paredes A, McManus M, Kwon HM, Strange K. Osmoregulation of Na(+)-inositol cotransporter activity and mRNA levels in brain glial cells. Am J Physiol. 1992 Dec; 263(6 Pt 1):C1282-8.
  35. Irazuzta J, McManus ML. Use of topically applied nitroglycerin in the treatment of purpura fulminans. J Pediatr. 1990 Dec; 117(6):993-5.
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