Craig McClain

Craig McClain, MD

1st Milton H. Alper Research Fellowship; Senior Associate in Perioperative Anesthesia

Assistant Professor of Anaesthesia, Harvard Medical School

  • Contact: 617-355-7737

  • Fax: 617-730-0894

Medical Services

Specialties

  • Neuroanesthesia
  • Anesthesia

Departments

  • Anesthesiology Perioperative and Pain Medicine
To schedule an appointment: Call 617-355-7737

Experience and Education

Education

Undergraduate

University of Texas, 1991

Austin, TX

Medical School

University of Texas Medical Branch, 1999

Galveston, TX

Pediatric Anesthesia

Boston Children's Hospital , 2003-2004

Boston, MA

Medicine

Lyndon Baines Johnson Hospital, 1999-2000

Houston, TX

Anesthesiology

University of Virginia, 2000-2003

Charlottesville, VA

Professional History


Publications

Publications powered by Harvard Catalyst Profiles
  1. Chan DM, Wong R, Runnels S, Muhizi E, McClain CD. Factors Influencing the Choice of Anesthesia as a Career by Undergraduates of the University of Rwanda. Anesth Analg. 2016 Aug; 123(2):481-7.
  2. Kirpich IA, Marsano LS, McClain CJ. Gut-liver axis, nutrition, and non-alcoholic fatty liver disease. Clin Biochem. 2015 Sep; 48(13-14):923-30.
  3. McClain CD, Soriano SG. Anesthesia for intracranial surgery in infants and children. Curr Opin Anaesthesiol. 2014 Oct; 27(5):465-9.
  4. Landrigan-Ossar M, McClain CD. Anesthesia for interventional radiology. Paediatr Anaesth. 2014 Jul; 24(7):698-702.
  5. Hoyler M, Finlayson SR, McClain CD, Meara JG, Hagander L. Shortage of doctors, shortage of data: a review of the global surgery, obstetrics, and anesthesia workforce literature. World J Surg. 2014 Feb; 38(2):269-80.
  6. McClain CD, Landrigan-Ossar M. Challenges in pediatric neuroanesthesia: awake craniotomy, intraoperative magnetic resonance imaging, and interventional neuroradiology. Anesthesiol Clin. 2014 Mar; 32(1):83-100.
  7. Hughes CD, McClain CD, Hagander L, Pierre JH, Groen RS, Kushner AL, Meara JG. Ratio of cesarean deliveries to total operations and surgeon nationality are potential proxies for surgical capacity in central Haiti. World J Surg. 2013 Jul; 37(7):1526-9.
  8. McClain CD, Holzman RS. Attenuating the perioperative stress response: a proposition of a simple solution. Minerva Anestesiol. 2013 Sep; 79(9):981-2.
  9. Hughes CD, Nash KA, Alkire BC, McClain CD, Hagander LE, Smithers CJ, Raymonville M, Sullivan SR, Riviello R, Rogers SO, Meara JG. The impact of natural disaster on pediatric surgical delivery: a review of Haiti six months before and after the 2010 earthquake. J Health Care Poor Underserved. 2012 May; 23(2):523-33.
  10. Khoriaty E, McClain CD, Permaul P, Smith ER, Rachid R. Intraoperative anaphylaxis induced by the gelatin component of thrombin-soaked gelfoam in a pediatric patient. Ann Allergy Asthma Immunol. 2012 Mar; 108(3):209-10.
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  12. McClain CD, Rockoff MA, Soriano SG. Anesthetic concerns for pediatric patients in an intraoperative MRI suite. Curr Opin Anaesthesiol. 2011 Oct; 24(5):480-6.
  13. Vendrame M, Kaleyias J, Loddenkemper T, Smith E, McClain C, Rockoff M, Manganaro S, McKenzie B, Gao L, Scott M, Bourgeois B, Kothare SV. Electroencephalogram monitoring during intracranial surgery for moyamoya disease. Pediatr Neurol. 2011 Jun; 44(6):427-32.
  14. Smith ER, McClain CD, Heeney M, Scott RM. Pial synangiosis in patients with moyamoya syndrome and sickle cell anemia: perioperative management and surgical outcome. Neurosurg Focus. 2009 Apr; 26(4):E10.
  15. McClain CD and McManus ML. Complications Following Operative Interventions for Vascular Anomalies in Pediatrics. Neurosurgical Anesthesia and Critical Care Medicine – Strategies for Prevention, Early Detection, and Management, edited by Brambrink A and Kirsch JR (in press). 2009.
  16. McClain CD and Soriano SG. Specific ICU Risks after Pediatric Neurosurgery in Perioperative Complications. Neurosurgical Anesthesia and Critical Care Medicine – Strategies for Prevention, Early Detection, and Management, edited by Brambrink A and Kirsch JR (in press). 2009.
  17. McClain CD. contributing author. How to Pick a Doctor, by Kyra Bobinet (in press). 2009.
  18. McClain CD and Soriano SG. Neurosurgery and Neurotraumatology: Anesthetic Considerations. Pediatric Anesthesia: Principles & Practice, edited by Bissonette B and Dalens BJ (in press). 2009.
  19. McClain CD, Soriano SG and Rockoff MA. Pediatric Neurosurgical Anesthesia. A Practice of Anesthesia for Infants and Children, edited by Cote CJ, Todres ID, Goudsouzian NG and Ryan JF (in press). 2008.
  20. McClain CD and McManus ML. Perioperative Pediatric Fluid Management. A Practice of Anesthesia for Infants and Children, edited by Cote CJ, Todres ID, Goudsouzian NG and Ryan JF (in press). 2008.
  21. McClain CD and Soriano SG. The Central Nervous System: Pediatric Neuroanesthesia. A Practical Approach to Pediatric Anesthesia, edited by Holzman RS, Mancuso T and Polaner D. 2008.
  22. McClain CD. Ethical Treatment of Combatants and Noncombatants. ASA Syllabus on Ethics. 2008.
  23. McClain CD, Soriano SG, Goumnerova LC, Black PM, Rockoff MA. Detection of unanticipated intracranial hemorrhage during intraoperative magnetic resonance image-guided neurosurgery. Report of two cases. J Neurosurg. 2007 May; 106(5 Suppl):398-400.
  24. McClain CD, Proctor MR, Soriano SG, Goumnerova LG and Rockoff MA. Initial Experience with a Mobile 1.5T MRI for Intraoperative Guidance in Pediatric Neurosurgery. J Neurosurg Anesthesiol. 2007; in press.
  25. McClain CD, McGowan FX, Kovatsis PG. Laparoscopic surgery in a patient with Fontan physiology. Anesth Analg. 2006 Oct; 103(4):856-8.
  26. Wolf GK, McClain CD, Zurakowski D, Dodson B, McManus ML. Total phenytoin concentrations do not accurately predict free phenytoin concentrations in critically ill children. Pediatr Crit Care Med. 2006 Sep; 7(5):434-9; quiz 440.
  27. McClain CD. Society of neurosurgical anesthesia and critical care scientific meeting. Anesthesiology. 2006 Apr; 104(4):898-9.
  28. McClain CD. Report of Scientific Meeting – SNACC 2005. Anesthesiology. 2006; 104(4):898-99.
  29. Yemen TA, McClain C. Muscular dystrophy, anesthesia and the safety of inhalational agents revisited; again. Paediatr Anaesth. 2006 Feb; 16(2):105-8.
  30. Yemen TA and McClain C. Muscular Dystrophy, Anesthesia, and the Safety of Inhalational Agents Revisited; Again. Paediatric Anesthesia. 2006; 16(2):105-8.
  31. Yen KL, Piva S, McClain CD, Smith ER, Riviello JJ, Robertson RL, Soriano SG, Scott RM and McManus ML. Regional Cerebral Blood Flow Monitoring by Thermal Diffusion Probe in Children with Moyamoya Syndrome Undergoing Pial Synangiosis. J Neurosurg Anesthesiol. 2006; 18(4):277.
  32. Gerhard Wolf MD, Craig McClain MD, David Zurakowski PhD, MPH, Brenda Dodson PharmD, Michael L. McManus MD, MPH. Safe and Effective Treatment with Phenytoin Requires Measurement of Free Levels in the Pediatric Intensive Care Unit. Pediatric Crit Care Med. 2006; 7:518.
  33. Yen KL, Piva S, McClain CD, Smith ER, Riviello JJ, Robertson RL, Soriano SG, Scott RM and McManus ML. Noninvasive Cerebral Oxygenation Monitoring by Near-Infrared Spectroscopy in Children with Moyamoya Syndrome Undergoing Pial Synangiosis. J Neurosurg Anesthesiol. 2006; 18(4):277-8.
  34. Louthan MV, Theriot JA, Zimmerman E, Stutts JT, McClain CJ. Decreased prevalence of nonalcoholic fatty liver disease in black obese children. J Pediatr Gastroenterol Nutr. 2005 Oct; 41(4):426-9.
  35. McClain CD. Should the Results of Animal Studies Change Clinical Anesthetic Care?. Society for Pediatric Anesthesia Newsletter. 2005; Summer.
  36. McClain CD, Wolf G, Dodson BL and McManus ML. Total and Unbound Phenytoin Levels in Critically Ill Children. Canadian Journal of Anesthesia. 2005; 52(Supplement 1):A166.
  37. McClain CD. Should the Results of Animal Studies Change Clinical Anesthetic Care? Point/Counterpoint. Society for Pediatric Anesthesia Newsletter. 2005; 3-4.
  38. McClain CD, Baum VC, Erdmann A. Concise Anatomy for Anesthesia. Crit Care Med. 2003; 31:1892.
  39. McClain CD. Pulmonary Artery Catheter: Cannot Wedge, Malfunction. Critical Care on Call, edited by Alan T. Lefor. 2002.
  40. Hatton J, Rapp RP, Kudsk KA, Brown RO, Luer MS, Bukar JG, Chen SA, McClain CJ, Gesundheit N, Dempsey RJ, Young B. Intravenous insulin-like growth factor-I (IGF-I) in moderate-to-severe head injury: a Phase II safety and efficacy trial. Neurosurg Focus. 1997 May 15; 2(5):ECP1; discussion 1 p following ECP1.
  41. Hatton J, Rapp RP, Kudsk KA, Brown RO, Luer MS, Bukar JG, Chen SA, McClain CJ, Gesundheit N, Dempsey RJ, Young B. Intravenous insulin-like growth factor-I (IGF-I) in moderate-to-severe head injury: a phase II safety and efficacy trial. J Neurosurg. 1997 May; 86(5):779-86.
  42. Zhang W, Grasso L, McClain CD, Gambel AM, Cha Y, Travali S, Deisseroth AB, Mercer WE. p53-independent induction of WAF1/CIP1 in human leukemia cells is correlated with growth arrest accompanying monocyte/macrophage differentiation. Cancer Res. 1995 Feb 1; 55(3):668-74.
  43. Zhang W, Randaw GS, Gau J, McClain CD, Guo XY, Shay JW and Deisseroth AB. The first intron of human H-ras is regulated by p53: Specific activation mediated by a p53-binding element and general repression by the N-terminus of p53. Int. J. Oncol. 1995; 7:1021-28.
  44. Zhang W, McClain C, Gau JP, Guo XY, Deisseroth AB. Hyperphosphorylation of p53 induced by okadaic acid attenuates its transcriptional activation function. Cancer Res. 1994 Aug 15; 54(16):4448-53.
  45. Ott L, Young B, Phillips R, McClain C, Adams L, Dempsey R, Tibbs P, Ryo UY. Altered gastric emptying in the head-injured patient: relationship to feeding intolerance. J Neurosurg. 1991 May; 74(5):738-42.
  46. Hill DB, Henderson LM, McClain CJ. Osmotic diarrhea induced by sugar-free theophylline solution in critically ill patients. JPEN J Parenter Enteral Nutr. 1991 May-Jun; 15(3):332-6.
  47. McClain CJ, Hennig B, Ott LG, Goldblum S, Young AB. Mechanisms and implications of hypoalbuminemia in head-injured patients. J Neurosurg. 1988 Sep; 69(3):386-92.
  48. Young AB, Ott LG, Beard D, Dempsey RJ, Tibbs PA, McClain CJ. The acute-phase response of the brain-injured patient. J Neurosurg. 1988 Sep; 69(3):375-80.
  49. Norton JA, Ott LG, McClain C, Adams L, Dempsey RJ, Haack D, Tibbs PA, Young AB. Intolerance to enteral feeding in the brain-injured patient. J Neurosurg. 1988 Jan; 68(1):62-6.
  50. McClain CJ, Twyman DL, Ott LG, Rapp RP, Tibbs PA, Norton JA, Kasarskis EJ, Dempsey RJ, Young B. Serum and urine zinc response in head-injured patients. J Neurosurg. 1986 Feb; 64(2):224-30.
  51. Bates J, McClain CJ. The effect of severe zinc deficiency on serum levels of albumin, transferrin, and prealbumin in man. Am J Clin Nutr. 1981 Sep; 34(9):1655-60.
To schedule an appointment: Call 617-355-7737

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