James E.  Lock

James Lock, MD

Cardiologist-in-Chief Emeritus and Chairman of the Department of Cardiology

Alexander S. Nadas Professor of Pediatrics, Harvard Medical School

Medical Services

Specialties

  • Interventional Catheterization
  • Cardiology

Departments

  • Cardiology
  • Cardiovascular Program

Programs

  • Cardiac Catheterization Labs
  • Fetal Cardiology Program
To schedule an appointment: Call 617-355-7313 or Request an Appointment

Experience and Education

Education

Undergraduate Degree

Case Western Reserve University, 1969

Cleveland, OH

Medical School

Stanford University School of Medicine, 1973

Stanford, CA

Internship

University of Minnesota Hospital & Clinics, 1973-1974

Minneapolis, MN

Residency

University of Minnesota Hospital & Clinics, 1974-1975

Minneapolis, MN

Fellowship

Hospital for Sick Children, 1977-1979

Toronto, CANADA

Certifications

  • Pediatrics, Pediatric Cardiology

Professional History

Dr. James Lock is Cardiologist-in-Chief and Chairman of the Department of Cardiology at Boston Children’s Hospital, and the Alexander S. Nadas Professor of Pediatrics at Harvard Medical School.  Dr. Lock attended medical school at Stanford University, pursued pediatric residency and cardiology fellowship at the University of Minnesota, and trained in cardiovascular physiology for two years at the University of Toronto, Hospital for Sick Children.  Scientific work on pulmonary vascular control was supported by an AHA Established Investigator Award, the March of Dimes (Basil O’Connor Award) and National Institutes of Health (RO1 HL).  Dr. Lock shifted his research focus to experimental interventional cardiology, providing most of the basic research in that field.  In 1984, he joined Boston Children’s Hospital as Director of the Cardiac Catheterization Laboratory, and became Department Chair in 1993.

Dr. Lock has invented several cardiac catheterization devices and has developed several dozen new non-surgical procedures to improve care for children with complex heart disease.  In September 1999, the CardioSEAL device developed by Dr. Lock and others became the first septal occlusion device to receive FDA approval for use inside the human heart.  He has authored or co-authored 250 peer-reviewed scientific papers.  He is the president of Boston Children’s Heart Foundation, the president of the Aldo Castaneda Foundation, and serves on the Finance Committee Board of Directors of Boston Children’s Hospital.

During his research career, Dr. Lock has trained nearly a hundred academic physicians in cardiopulmonary physiology, experimental interventional cardiology and clinical interventional cardiology.  Beginning five years ago, he and his colleagues started a highly innovative program to standardize clinical care in a fashion that improves outcomes, reduces unnecessary utilization and supports innovation. That program, termed SCAMPs, is now rapidly gaining acceptance throughout the medical community.

Publications

Publications powered by Harvard Catalyst Profiles
  1. Farias M, Friedman KG, Lock JE, Newburger JW, Rathod RH. Differentiating standardized clinical assessment and management plans from clinical practice guidelines. Acad Med. 2015 Aug; 90(8):1002.
  2. Couturier J, Kimber M, Lock J, Barwick M, McVey G, Findlay S, Webb C, Boettcher M, Niccols A, Woodford T. Implementing highly specialized and evidence-based pediatric eating disorder treatment: protocol for a mixed methods evaluation. Implement Sci. 2015; 10:40.
  3. Farias M, Friedman KG, Lock JE, Rathod RH. Gathering and learning from relevant clinical data: a new framework. Acad Med. 2015 Feb; 90(2):143-8.
  4. Eastaugh LJ, Thiagarajan RR, Darst JR, McElhinney DB, Lock JE, Marshall AC. Percutaneous left atrial decompression in patients supported with extracorporeal membrane oxygenation for cardiac disease. Pediatr Crit Care Med. 2015 Jan; 16(1):59-65.
  5. Morray BH, Bergersen L, Lock JE, Marshall AC. Occult progressive pulmonary arterial occlusion associated with right ventricular hypertension in patients with systemic arteriopathy. Congenit Heart Dis. 2015 Mar-Apr; 10(2):E60-7.
  6. Freud LR, McElhinney DB, Marshall AC, Marx GR, Friedman KG, del Nido PJ, Emani SM, Lafranchi T, Silva V, Wilkins-Haug LE, Benson CB, Lock JE, Tworetzky W. Fetal aortic valvuloplasty for evolving hypoplastic left heart syndrome: postnatal outcomes of the first 100 patients. Circulation. 2014 Aug 19; 130(8):638-45.
  7. Stiles-Shields C, DclinPsy BB, Lock J, Le Grange D. The effect of driven exercise on treatment outcomes for adolescents with anorexia and bulimia nervosa. Int J Eat Disord. 2015 May; 48(4):392-6.
  8. Kalish BT, Tworetzky W, Benson CB, Wilkins-Haug L, Mizrahi-Arnaud A, McElhinney DB, Lock JE, Marshall AC. Technical challenges of atrial septal stent placement in fetuses with hypoplastic left heart syndrome and intact atrial septum. Catheter Cardiovasc Interv. 2014 Jul 1; 84(1):77-85.
  9. Hill AC, Brown DW, Colan SD, Gauvreau K, del Nido PJ, Lock JE, Rathod RH. Mixed aortic valve disease in the young: initial observations. Pediatr Cardiol. 2014 Aug; 35(6):934-42.
  10. Runfola CD, Allison KC, Hardy KK, Lock J, Peebles R. Prevalence and clinical significance of night eating syndrome in university students. J Adolesc Health. 2014 Jul; 55(1):41-8.
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  12. Quiñonez LG, Breitbart R, Tworetsky W, Lock JE, Marshall AC, Emani SM. Stented bovine jugular vein graft (Melody valve) for surgical mitral valve replacement in infants and children. J Thorac Cardiovasc Surg. 2014 Oct; 148(4):1443-9.
  13. Hainstock MR, Marshall AC, Lock JE, McElhinney DB. Angioplasty of obstructed homograft conduits in the right ventricular outflow tract with ultra-noncompliant balloons: assessment of therapeutic efficacy and conduit tears. Circ Cardiovasc Interv. 2013 Dec; 6(6):671-9.
  14. Hallbergson A, Lock JE, Marshall AC. Frequency and risk of in-stent stenosis following pulmonary artery stenting. Am J Cardiol. 2014 Feb 1; 113(3):541-5.
  15. Le Grange D, Accurso EC, Lock J, Agras S, Bryson SW. Early weight gain predicts outcome in two treatments for adolescent anorexia nervosa. Int J Eat Disord. 2014 Mar; 47(2):124-9.
  16. Porras D, Brown DW, Rathod R, Friedman K, Gauvreau K, Lock JE, Esch JJ, Bergersen L, Marshall AC. Acute outcomes after introduction of a standardized clinical assessment and management plan (SCAMP) for balloon aortic valvuloplasty in congenital aortic stenosis. Congenit Heart Dis. 2014 Jul-Aug; 9(4):316-25.
  17. Katzman DK, Peebles R, Sawyer SM, Lock J, Le Grange D. The role of the pediatrician in family-based treatment for adolescent eating disorders: opportunities and challenges. J Adolesc Health. 2013 Oct; 53(4):433-40.
  18. Morray BH, McElhinney DB, Cheatham JP, Zahn EM, Berman DP, Sullivan PM, Lock JE, Jones TK. Risk of coronary artery compression among patients referred for transcatheter pulmonary valve implantation: a multicenter experience. Circ Cardiovasc Interv. 2013 Oct 1; 6(5):535-42.
  19. Darcy AM, Bryson SW, Agras WS, Fitzpatrick KK, Le Grange D, Lock J. Do in-vivo behaviors predict early response in family-based treatment for anorexia nervosa? Behav Res Ther. 2013 Nov; 51(11):762-6.
  20. Lock J, Agras WS, Le Grange D, Couturier J, Safer D, Bryson SW. Do end of treatment assessments predict outcome at follow-up in eating disorders? Int J Eat Disord. 2013 Dec; 46(8):771-8.
  21. Cunningham JW, McElhinney DB, Gauvreau K, Bergersen L, Lacro RV, Marshall AC, Smoot L, Lock JE. Outcomes after primary transcatheter therapy in infants and young children with severe bilateral peripheral pulmonary artery stenosis. Circ Cardiovasc Interv. 2013 Aug; 6(4):460-7.
  22. Porras D, Stein DR, Ferguson MA, Chaudry G, Alomari A, Vakili K, Fishman SJ, Lock JE, Kim HB. Midaortic syndrome: 30 years of experience with medical, endovascular and surgical management. Pediatr Nephrol. 2013 Oct; 28(10):2023-33.
  23. Buber J, Bergersen L, Lock JE, Gauvreau K, Esch JJ, Landzberg MJ, Valente AM, Sandora TJ, Marshall AC. Bloodstream infections occurring in patients with percutaneously implanted bioprosthetic pulmonary valve: a single-center experience. Circ Cardiovasc Interv. 2013 Jun; 6(3):301-10.
  24. Farias M, Jenkins K, Lock J, Rathod R, Newburger J, Bates DW, Safran DG, Friedman K, Greenberg J. Standardized Clinical Assessment And Management Plans (SCAMPs) provide a better alternative to clinical practice guidelines. Health Aff (Millwood). 2013 May; 32(5):911-20.
  25. Prakash A, Satiroglu E, Porras D, McElhinney DB, Keane JF, Lock JE, Geva T, King W, Powell AJ. Risk factors for profuse systemic-to-pulmonary artery collateral burden in hypoplastic left heart syndrome. Am J Cardiol. 2013 Aug 1; 112(3):400-4.
  26. Myers PO, del Nido PJ, McElhinney DB, Khalpey Z, Lock JE, Baird CW. Annulus upsizing for mitral valve re-replacement in children. J Thorac Cardiovasc Surg. 2013 Aug; 146(2):347-51.
  27. Darcy AM, Hardy KK, Crosby RD, Lock J, Peebles R. Factor structure of the Eating Disorder Examination Questionnaire (EDE-Q) in male and female college athletes. Body Image. 2013 Jun; 10(3):399-405.
  28. Esch JJ, Shah PB, Cockrill BA, Farber HW, Landzberg MJ, Mehra MR, Mullen MP, Opotowsky AR, Waxman AB, Lock JE, Marshall AC. Transcatheter Potts shunt creation in patients with severe pulmonary arterial hypertension: initial clinical experience. J Heart Lung Transplant. 2013 Apr; 32(4):381-7.
  29. Assenza GE, McElhinney DB, Valente AM, Pearson DD, Volpe M, Martucci G, Landzberg MJ, Lock JE. Transcatheter closure of post-myocardial infarction ventricular septal rupture. Circ Cardiovasc Interv. 2013 Feb; 6(1):59-67.
  30. Kazanci SY, McElhinney DB, Thiagarajan R, Bergersen L, Wilson JM, Marshall AC, Lock JE, Mullen MP. Obstruction of the superior vena cava after neonatal extracorporeal membrane oxygenation: association with chylothorax and outcome of transcatheter treatment. Pediatr Crit Care Med. 2013 Jan; 14(1):37-43.
  31. Friedman KG, McElhinney DB, Rhodes J, Powell AJ, Colan SD, Lock JE, Brown DW. Left ventricular diastolic function in children and young adults with congenital aortic valve disease. Am J Cardiol. 2013 Jan 15; 111(2):243-9.
  32. Esch JJ, Bergersen L, McElhinney DB, Porras D, Lock JE, Marshall AC. Wire-related pulmonary artery injury during pediatric and adult congenital interventional cardiac catheterization. Congenit Heart Dis. 2013 Jul-Aug; 8(4):296-301.
  33. Emani SM, McElhinney DB, Tworetzky W, Myers PO, Schroeder B, Zurakowski D, Pigula FA, Marx GR, Lock JE, del Nido PJ. Staged left ventricular recruitment after single-ventricle palliation in patients with borderline left heart hypoplasia. J Am Coll Cardiol. 2012 Nov 6; 60(19):1966-74.
  34. Abdullah I, Ramirez FB, McElhinney DB, Lock JE, del Nido PJ, Emani S. Modification of a stented bovine jugular vein conduit (melody valve) for surgical mitral valve replacement. Ann Thorac Surg. 2012 Oct; 94(4):e97-8.
  35. Porras D, McElhinney DB, Del Nido P, Lock JE, Meadows J, Marshall AC. Clinical and stent-related outcomes after transcatheter or operative placement of bare-metal stents in the ventricular septum or subvalvar systemic outflow tract. Circ Cardiovasc Interv. 2012 Aug 1; 5(4):570-81.
  36. Friedman KG, McElhinney DB, Colan SD, Porras D, Powell AJ, Lock JE, Brown DW. Left ventricular remodeling and improvement in diastolic function after balloon aortic valvuloplasty for congenital aortic stenosis. Circ Cardiovasc Interv. 2012 Aug 1; 5(4):549-54.
  37. Schlingmann TR, Thiagarajan RR, Gauvreau K, Lofgren KC, Zaplin M, Connor JA, del Nido PJ, Lock JE, Jenkins KJ. Cardiac medical conditions have become the leading cause of death in children with heart disease. Congenit Heart Dis. 2012 Nov-Dec; 7(6):551-8.
  38. Carr M, Bergersen L, Marshall AC, Keane JF, Lock JE, Emani SM, McElhinney DB. Bare metal stenting for obstructed small diameter homograft conduits in the right ventricular outflow tract. Catheter Cardiovasc Interv. 2013 Jan 1; 81(1):E44-52.
  39. Jones M, Völker U, Lock J, Taylor CB, Jacobi C. Family-based early intervention for anorexia nervosa. Eur Eat Disord Rev. 2012 May; 20(3):e137-43.
  40. Brownstone L, Anderson K, Beenhakker J, Lock J, Le Grange D. Recruitment and retention in an adolescent anorexia nervosa treatment trial. Int J Eat Disord. 2012 Sep; 45(6):812-5.
  41. Balasubramanian S, Marshall AC, Gauvreau K, Peng LF, Nugent AW, Lock JE, McElhinney DB. Outcomes after stent implantation for the treatment of congenital and postoperative pulmonary vein stenosis in children. Circ Cardiovasc Interv. 2012 Feb 1; 5(1):109-17.
  42. Le Grange D, Lock J, Agras WS, Moye A, Bryson SW, Jo B, Kraemer HC. Moderators and mediators of remission in family-based treatment and adolescent focused therapy for anorexia nervosa. Behav Res Ther. 2012 Feb; 50(2):85-92.
  43. Hasan BS, McElhinney DB, Brown DW, Cheatham JP, Vincent JA, Hellenbrand WE, Jones TK, Zahn EM, Lock JE. Short-term performance of the transcatheter Melody valve in high-pressure hemodynamic environments in the pulmonary and systemic circulations. Circ Cardiovasc Interv. 2011 Dec 1; 4(6):615-20.
  44. McElhinney DB, Cheatham JP, Jones TK, Lock JE, Vincent JA, Zahn EM, Hellenbrand WE. Stent fracture, valve dysfunction, and right ventricular outflow tract reintervention after transcatheter pulmonary valve implantation: patient-related and procedural risk factors in the US Melody Valve Trial. Circ Cardiovasc Interv. 2011 Dec 1; 4(6):602-14.
  45. Bergersen L, Gauvreau K, Justino H, Nugent A, Rome J, Kreutzer J, Rhodes J, Nykanen D, Zahn E, Latson L, Moore P, Lock J, Jenkins K. Randomized trial of cutting balloon compared with high-pressure angioplasty for the treatment of resistant pulmonary artery stenosis. Circulation. 2011 Nov 29; 124(22):2388-96.
  46. Saleeb SF, Li WY, Warren SZ, Lock JE. Effectiveness of screening for life-threatening chest pain in children. Pediatrics. 2011 Nov; 128(5):e1062-8.
  47. Bergersen L, Gauvreau K, Foerster SR, Marshall AC, McElhinney DB, Beekman RH, Hirsch R, Kreutzer J, Balzer D, Vincent J, Hellenbrand WE, Holzer R, Cheatham JP, Moore JW, Burch G, Armsby L, Lock JE, Jenkins KJ. Catheterization for Congenital Heart Disease Adjustment for Risk Method (CHARM). JACC Cardiovasc Interv. 2011 Sep; 4(9):1037-46.
  48. Friedman KG, Kane DA, Rathod RH, Renaud A, Farias M, Geggel R, Fulton DR, Lock JE, Saleeb SF. Management of pediatric chest pain using a standardized assessment and management plan. Pediatrics. 2011 Aug; 128(2):239-45.
  49. Robinson JD, Rathod RH, Brown DW, Del Nido PJ, Lock JE, McElhinney DB, Bacha EA, Marshall AC. The evolving role of intraoperative balloon pulmonary valvuloplasty in valve-sparing repair of tetralogy of Fallot. J Thorac Cardiovasc Surg. 2011 Dec; 142(6):1367-73.
  50. Holzer RJ, Gauvreau K, Kreutzer J, Leahy R, Murphy J, Lock JE, Cheatham JP, Bergersen L. Balloon angioplasty and stenting of branch pulmonary arteries: adverse events and procedural characteristics: results of a multi-institutional registry. Circ Cardiovasc Interv. 2011 Jun; 4(3):287-96.
  51. Bergersen L, Gauvreau K, Marshall A, Kreutzer J, Beekman R, Hirsch R, Foerster S, Balzer D, Vincent J, Hellenbrand W, Holzer R, Cheatham J, Moore J, Lock J, Jenkins K. Procedure-type risk categories for pediatric and congenital cardiac catheterization. Circ Cardiovasc Interv. 2011 Apr 1; 4(2):188-94.
  52. Vogel M, McElhinney DB, Wilkins-Haug LE, Marshall AC, Benson CB, Juraszek AL, Silva V, Lock JE, Marx GR, Tworetzky W. Aortic stenosis and severe mitral regurgitation in the fetus resulting in giant left atrium and hydrops: pathophysiology, outcomes, and preliminary experience with pre-natal cardiac intervention. J Am Coll Cardiol. 2011 Jan 18; 57(3):348-55.
  53. Brown DW, Dipilato AE, Chong EC, Gauvreau K, McElhinney DB, Colan SD, Lock JE. Sudden unexpected death after balloon valvuloplasty for congenital aortic stenosis. J Am Coll Cardiol. 2010 Nov 30; 56(23):1939-46.
  54. Brown DW, Dipilato AE, Chong EC, Lock JE, McElhinney DB. Aortic valve reinterventions after balloon aortic valvuloplasty for congenital aortic stenosis intermediate and late follow-up. J Am Coll Cardiol. 2010 Nov 16; 56(21):1740-9.
  55. Loeb KL, Le Grange D, Hildebrandt T, Greif R, Lock J, Alfano L. Eating disorders in youth: diagnostic variability and predictive validity. Int J Eat Disord. 2011 Dec; 44(8):692-702.
  56. Lock J, Le Grange D, Agras WS, Moye A, Bryson SW, Jo B. Randomized clinical trial comparing family-based treatment with adolescent-focused individual therapy for adolescents with anorexia nervosa. Arch Gen Psychiatry. 2010 Oct; 67(10):1025-32.
  57. Marshall AC, Lock JE. Still working on our short game: technique and accuracy of stent placement in congenital heart disease. JACC Cardiovasc Interv. 2010 Oct; 3(10):1087-8.
  58. Robinson JD, Del Nido PJ, Geggel RL, Perez-Atayde AR, Lock JE, Powell AJ. Left ventricular diastolic heart failure in teenagers who underwent balloon aortic valvuloplasty in early infancy. Am J Cardiol. 2010 Aug 1; 106(3):426-9.
  59. McElhinney DB, Hellenbrand WE, Zahn EM, Jones TK, Cheatham JP, Lock JE, Vincent JA. Short- and medium-term outcomes after transcatheter pulmonary valve placement in the expanded multicenter US melody valve trial. Circulation. 2010 Aug 3; 122(5):507-16.
  60. Rathod RH, Farias M, Friedman KG, Graham D, Fulton DR, Newburger JW, Colan S, Jenkins K, Lock JE. A novel approach to gathering and acting on relevant clinical information: SCAMPs. Congenit Heart Dis. 2010 Jul-Aug; 5(4):343-53.
  61. Friedman KG, Rathod RH, Farias M, Graham D, Powell AJ, Fulton DR, Newburger JW, Colan SD, Jenkins KJ, Lock JE. Resource utilization after introduction of a standardized clinical assessment and management plan. Congenit Heart Dis. 2010 Jul-Aug; 5(4):374-81.
  62. Darst JR, Newburger JW, Resch S, Rathod RH, Lock JE. Deciding without data. Congenit Heart Dis. 2010 Jul-Aug; 5(4):339-42.
  63. Fortescue EB, Lock JE, Galvin T, McElhinney DB. To close or not to close: the very small patent ductus arteriosus. Congenit Heart Dis. 2010 Jul-Aug; 5(4):354-65.
  64. Lock JE. Is rationing the only way out? Congenit Heart Dis. 2010 Jul-Aug; 5(4):338.
  65. Kane DA, Fulton DR, Saleeb S, Zhou J, Lock JE, Geggel RL. Needles in hay: chest pain as the presenting symptom in children with serious underlying cardiac pathology. Congenit Heart Dis. 2010 Jul-Aug; 5(4):366-73.
  66. Peng LF, Lock JE, Nugent AW, Jenkins KJ, McElhinney DB. Comparison of conventional and cutting balloon angioplasty for congenital and postoperative pulmonary vein stenosis in infants and young children. Catheter Cardiovasc Interv. 2010 Jun 1; 75(7):1084-90.
  67. Valente AM, Lock JE, Gauvreau K, Rodriguez-Huertas E, Joyce C, Armsby L, Bacha EA, Landzberg MJ. Predictors of long-term adverse outcomes in patients with congenital coronary artery fistulae. Circ Cardiovasc Interv. 2010 Apr; 3(2):134-9.
  68. McElhinney DB, Tworetzky W, Lock JE. Current status of fetal cardiac intervention. Circulation. 2010 Mar 16; 121(10):1256-63.
  69. Harrild DM, Powell AJ, Tran TX, Trang TX, Geva T, Lock JE, Rhodes J, McElhinney DB. Long-term pulmonary regurgitation following balloon valvuloplasty for pulmonary stenosis risk factors and relationship to exercise capacity and ventricular volume and function. J Am Coll Cardiol. 2010 Mar 9; 55(10):1041-7.
  70. Bergersen L, Marshall A, Gauvreau K, Beekman R, Hirsch R, Foerster S, Balzer D, Vincent J, Hellenbrand W, Holzer R, Cheatham J, Moore J, Lock J, Jenkins K. Adverse event rates in congenital cardiac catheterization - a multi-center experience. Catheter Cardiovasc Interv. 2010 Feb 15; 75(3):389-400.
  71. Hasan BS, Keane JF, Tworetzky W, Lock JE, Marshall AC. Postnatal angiographic appearance of left ventricular myocardium in fetal patients with aortic stenosis having in-utero aortic valvuloplasty. Am J Cardiol. 2009 Nov 1; 104(9):1271-5.
  72. Zahn EM, Hellenbrand WE, Lock JE, McElhinney DB. Implantation of the melody transcatheter pulmonary valve in patients with a dysfunctional right ventricular outflow tract conduit early results from the u.s. Clinical trial. J Am Coll Cardiol. 2009 Oct 27; 54(18):1722-9.
  73. McElhinney DB, Marshall AC, Wilkins-Haug LE, Brown DW, Benson CB, Silva V, Marx GR, Mizrahi-Arnaud A, Lock JE, Tworetzky W. Predictors of technical success and postnatal biventricular outcome after in utero aortic valvuloplasty for aortic stenosis with evolving hypoplastic left heart syndrome. Circulation. 2009 Oct 13; 120(15):1482-90.
  74. Tworetzky W, McElhinney DB, Marx GR, Benson CB, Brusseau R, Morash D, Wilkins-Haug LE, Lock JE, Marshall AC. In utero valvuloplasty for pulmonary atresia with hypoplastic right ventricle: techniques and outcomes. Pediatrics. 2009 Sep; 124(3):e510-8.
  75. Robinson JD, Marx GR, Del Nido PJ, Lock JE, McElhinney DB. Effectiveness of balloon valvuloplasty for palliation of mitral stenosis after repair of atrioventricular canal defects. Am J Cardiol. 2009 Jun 15; 103(12):1770-3.
  76. Senthilnathan S, Gauvreau K, Marshall AC, Lock JE, Bergersen L. Contrast administration in pediatric cardiac catheterization: dose and adverse events. Catheter Cardiovasc Interv. 2009 May 1; 73(6):814-20.
  77. Maglione J, Bergersen L, Lock JE, McElhinney DB. Ultra-high-pressure balloon angioplasty for treatment of resistant stenoses within or adjacent to previously implanted pulmonary arterial stents. Circ Cardiovasc Interv. 2009 Feb; 2(1):52-8.
  78. Marshall AC, Levine J, Morash D, Silva V, Lock JE, Benson CB, Wilkins-Haug LE, McElhinney DB, Tworetzky W. Results of in utero atrial septoplasty in fetuses with hypoplastic left heart syndrome. Prenat Diagn. 2008 Nov; 28(11):1023-8.
  79. Xu J, Han J, Long YS, Lock J, Weir GC, Epstein PN, Liu YQ. Malic enzyme is present in mouse islets and modulates insulin secretion. Diabetologia. 2008 Dec; 51(12):2281-9.
  80. Selamet Tierney ES, Pigula FA, Berul CI, Lock JE, del Nido PJ, McElhinney DB. Mitral valve replacement in infants and children 5 years of age or younger: evolution in practice and outcome over three decades with a focus on supra-annular prosthesis implantation. J Thorac Cardiovasc Surg. 2008 Oct; 136(4):954-61, 961.e1-3.
  81. Brown DW, Chong EC, Gauvreau K, Keane JF, Lock JE, Marshall AC. Aortic wall injury as a complication of neonatal aortic valvuloplasty: incidence and risk factors. Circ Cardiovasc Interv. 2008 Aug; 1(1):53-9.
  82. Parrott AC, Lock J, Conner AC, Kissling C, Thome J. Dance clubbing on MDMA and during abstinence from Ecstasy/MDMA: prospective neuroendocrine and psychobiological changes. Neuropsychobiology. 2008; 57(4):165-80.
  83. Bergersen L, Gauvreau K, Lock JE, Jenkins KJ. A risk adjusted method for comparing adverse outcomes among practitioners in pediatric and congenital cardiac catheterization. Congenit Heart Dis. 2008 Jul-Aug; 3(4):230-40.
  84. Lock J, Couturier J, Agras WS. Costs of remission and recovery using family therapy for adolescent anorexia nervosa: a descriptive report. Eat Disord. 2008 Jul-Sep; 16(4):322-30.
  85. Bergersen L, Gauvreau K, Jenkins KJ, Lock JE. Adverse event rates in congenital cardiac catheterization: a new understanding of risks. Congenit Heart Dis. 2008 Mar-Apr; 3(2):90-105.
  86. Khairy P, Fernandes SM, Mayer JE, Triedman JK, Walsh EP, Lock JE, Landzberg MJ. Long-term survival, modes of death, and predictors of mortality in patients with Fontan surgery. Circulation. 2008 Jan 1; 117(1):85-92.
  87. Lock J, Marshall AC. Invited commentary. Ann Thorac Surg. 2007 Nov; 84(5):1638-9.
  88. Lim DS, Forbes TJ, Rothman A, Lock JE, Landzberg MJ. Transcatheter closure of high-risk muscular ventricular septal defects with the CardioSEAL occluder: initial report from the CardioSEAL VSD registry. Catheter Cardiovasc Interv. 2007 Nov 1; 70(5):740-4.
  89. Sutton NJ, Peng L, Lock JE, Lang P, Marx GR, Curran TJ, O'Neill JA, Picard ST, Rhodes J. Effect of pulmonary artery angioplasty on exercise function after repair of tetralogy of Fallot. Am Heart J. 2008 Jan; 155(1):182-6.
  90. Selamet Tierney ES, Wald RM, McElhinney DB, Marshall AC, Benson CB, Colan SD, Marcus EN, Marx GR, Levine JC, Wilkins-Haug L, Lock JE, Tworetzky W. Changes in left heart hemodynamics after technically successful in-utero aortic valvuloplasty. Ultrasound Obstet Gynecol. 2007 Oct; 30(5):715-20.
  91. Mizrahi-Arnaud A, Tworetzky W, Bulich LA, Wilkins-Haug LE, Marshall AC, Benson CB, Lock JE, McElhinney DB. Pathophysiology, management, and outcomes of fetal hemodynamic instability during prenatal cardiac intervention. Pediatr Res. 2007 Sep; 62(3):325-30.
  92. Vida VL, Bacha EA, Larrazabal A, Gauvreau K, Thiagaragan R, Fynn-Thompson F, Pigula FA, Mayer JE, del Nido PJ, Tworetzky W, Lock JE, Marshall AC. Hypoplastic left heart syndrome with intact or highly restrictive atrial septum: surgical experience from a single center. Ann Thorac Surg. 2007 Aug; 84(2):581-5; discussion 586.
  93. Laybutt DR, Hawkins YC, Lock J, Lebet J, Sharma A, Bonner-Weir S, Weir GC. Influence of diabetes on the loss of beta cell differentiation after islet transplantation in rats. Diabetologia. 2007 Oct; 50(10):2117-25.
  94. Lee TH, Torchiana DF, Lock JE. Is zero the ideal death rate? N Engl J Med. 2007 Jul 12; 357(2):111-3.
  95. Lock JE. Device availability for the child with heart disease. J Am Coll Cardiol. 2007 Jun 5; 49(22):2222.
  96. Meadows J, Pigula F, Lock J, Marshall A. Transcatheter creation and enlargement of ventricular septal defects for relief of ventricular hypertension. J Thorac Cardiovasc Surg. 2007 Apr; 133(4):912-8.
  97. Nordmeyer J, Khambadkone S, Coats L, Schievano S, Lurz P, Parenzan G, Taylor AM, Lock JE, Bonhoeffer P. Risk stratification, systematic classification, and anticipatory management strategies for stent fracture after percutaneous pulmonary valve implantation. Circulation. 2007 Mar 20; 115(11):1392-7.
  98. Qureshi AM, McElhinney DB, Lock JE, Landzberg MJ, Lang P, Marshall AC. Acute and intermediate outcomes, and evaluation of injury to the aortic wall, as based on 15 years experience of implanting stents to treat aortic coarctation. Cardiol Young. 2007 Jun; 17(3):307-18.
  99. Tzifa A, Marshall AC, McElhinney DB, Lock JE, Geggel RL. Endovascular treatment for superior vena cava occlusion or obstruction in a pediatric and young adult population: a 22-year experience. J Am Coll Cardiol. 2007 Mar 6; 49(9):1003-9.
  100. Pereira T, Lock J, Oggins J. Role of therapeutic alliance in family therapy for adolescent anorexia nervosa. Int J Eat Disord. 2006 Dec; 39(8):677-84.
  101. Sutton N, Lock JE, Geggel RL. Cardiac catheterization in infants weighing less than 1,500 grams. Catheter Cardiovasc Interv. 2006 Dec; 68(6):948-56.
  102. Forsberg S, Lock J. The relationship between perfectionism, eating disorders and athletes: a review. Minerva Pediatr. 2006 Dec; 58(6):525-36.
  103. Knauth AL, Gauvreau K, Powell AJ, Landzberg MJ, Walsh EP, Lock JE, del Nido PJ, Geva T. Ventricular size and function assessed by cardiac MRI predict major adverse clinical outcomes late after tetralogy of Fallot repair. Heart. 2008 Feb; 94(2):211-6.
  104. Lock J, le Grange D, Forsberg S, Hewell K. Is family therapy useful for treating children with anorexia nervosa? Results of a case series. J Am Acad Child Adolesc Psychiatry. 2006 Nov; 45(11):1323-8.
  105. Salvin JW, McElhinney DB, Colan SD, Gauvreau K, del Nido PJ, Jenkins KJ, Lock JE, Tworetzky W. Fetal tricuspid valve size and growth as predictors of outcome in pulmonary atresia with intact ventricular septum. Pediatrics. 2006 Aug; 118(2):e415-20.
  106. Bergersen L, Lock JE. What is the current option of first choice for treatment of pulmonary arterial stenosis? Cardiol Young. 2006 Aug; 16(4):329-38.
  107. Nugent AW, Britt A, Gauvreau K, Piercey GE, Lock JE, Jenkins KJ. Device closure rates of simple atrial septal defects optimized by the STARFlex device. J Am Coll Cardiol. 2006 Aug 1; 48(3):538-44.
  108. Wilkins-Haug LE, Tworetzky W, Benson CB, Marshall AC, Jennings RW, Lock JE. Factors affecting technical success of fetal aortic valve dilation. Ultrasound Obstet Gynecol. 2006 Jul; 28(1):47-52.
  109. Lock J, Couturier J, Agras WS. Comparison of long-term outcomes in adolescents with anorexia nervosa treated with family therapy. J Am Acad Child Adolesc Psychiatry. 2006 Jun; 45(6):666-72.
  110. Peng LF, McElhinney DB, Nugent AW, Powell AJ, Marshall AC, Bacha EA, Lock JE. Endovascular stenting of obstructed right ventricle-to-pulmonary artery conduits: a 15-year experience. Circulation. 2006 Jun 6; 113(22):2598-605.
  111. Colan SD, McElhinney DB, Crawford EC, Keane JF, Lock JE. Validation and re-evaluation of a discriminant model predicting anatomic suitability for biventricular repair in neonates with aortic stenosis. J Am Coll Cardiol. 2006 May 2; 47(9):1858-65.
  112. Meadows J, Marshall AC, Lock JE, Scheurer M, Laussen PC, Bacha EA. A hybrid approach to stabilization and repair of obstructed total anomalous pulmonary venous connection in a critically ill newborn infant. J Thorac Cardiovasc Surg. 2006 Apr; 131(4):e1-2.
  113. Mäkikallio K, McElhinney DB, Levine JC, Marx GR, Colan SD, Marshall AC, Lock JE, Marcus EN, Tworetzky W. Fetal aortic valve stenosis and the evolution of hypoplastic left heart syndrome: patient selection for fetal intervention. Circulation. 2006 Mar 21; 113(11):1401-5.
  114. Bergersen L, Gauvreau K, Lock JE, Jenkins KJ. Recent results of pulmonary arterial angioplasty: the differences between proximal and distal lesions. Cardiol Young. 2005 Dec; 15(6):597-604.
  115. Bergersen L, Jenkins KJ, Gauvreau K, Lock JE. Follow-up results of Cutting Balloon angioplasty used to relieve stenoses in small pulmonary arteries. Cardiol Young. 2005 Dec; 15(6):605-10.
  116. McElhinney DB, Marshall AC, Lang P, Lock JE, Mayer JE. Creation of a brachial arteriovenous fistula for treatment of pulmonary arteriovenous malformations after cavopulmonary anastomosis. Ann Thorac Surg. 2005 Nov; 80(5):1604-9.
  117. McElhinney DB, Kreutzer J, Lang P, Mayer JE, del Nido PJ, Lock JE. Incorporation of the hepatic veins into the cavopulmonary circulation in patients with heterotaxy and pulmonary arteriovenous malformations after a Kawashima procedure. Ann Thorac Surg. 2005 Nov; 80(5):1597-603.
  118. Graham TP, Beekman RH, Allen HD, Bricker JT, Freed MD, Hurwitz RA, McQuinn TC, Schieken RM, Strong WB, Zahka KG, Sanders SP, Colan SD, Cordes TM, Donofrio MT, Ensing GJ, Geva T, Kimball TR, Sahn DJ, Silverman NH, Sklansky MS, Weinberg PM, Hellenbrand WE, Lloyd TR, Lock JE, Mullins CE, Romes JJ, Teitel DF, Vetter VL, Silka MJ, Van Hare GF, Walsh EP, Kulik T, Giglia TM, Kocis KC, Mahoney LT, Schwartz SM, Wernovsky G, Wessel DL, Murphy D, Foster E, Benson DW, Baldwin HS, Hirshfeld JW, Kugler JD, Moskowitz WB, Creager MA, Lorell BH, Merli G, Rodgers GP, Rutherford JD, Tracy CM, Weitz HH. ACCF/AHA/AAP recommendations for training in pediatric cardiology. A report of the American College of Cardiology Foundation/American Heart Association/American College of Physicians Task Force on Clinical Competence (ACC/AHA/AAP Writing Committee to Develop Training Recommendations for Pediatric Cardiology). Circulation. 2005 Oct 18; 112(16):2555-80.
  119. Tworetzky W, del Nido PJ, Powell AJ, Marshall AC, Lock JE, Geva T. Usefulness of magnetic resonance imaging of left ventricular endocardial fibroelastosis in infants after fetal intervention for aortic valve stenosis. Am J Cardiol. 2005 Dec 1; 96(11):1568-70.
  120. Allen HD, Bricker JT, Freed MD, Hurwitz RA, McQuinn TC, Schieken RM, Strong WB, Zahka KG, Sanders SP, Colan SD, Cordes TM, Donofrio MT, Ensing GJ, Geva T, Kimball TR, Sahn DJ, Silverman NH, Sklansky MS, Weinberg PM, Beekman RH, Hellenbrand WE, Lloyd TR, Lock JE, Mullins CE, Rome JJ, Teitel DF, Vetter VL, Silka MJ, Van Hare GF, Walsh EP, Kulik T, Giglia TM, Kocis KC, Mahoney LT, Schwartz SM, Wernovsky G, Wessel DL, Murphy DJ, Foster E, Benson DW, Baldwin HS, Mahoney LT, McQuinn TC. ACC/AHA/AAP recommendations for training in pediatric cardiology. Pediatrics. 2005 Dec; 116(6):1574-96.
  121. Beekman RH, Hellenbrand WE, Lloyd TR, Lock JE, Mullins CE, Rome JJ, Teitel DF. ACCF/AHA/AAP recommendations for training in pediatric cardiology. Task force 3: training guidelines for pediatric cardiac catheterization and interventional cardiology endorsed by the Society for Cardiovascular Angiography and Interventions. J Am Coll Cardiol. 2005 Oct 4; 46(7):1388-90.
  122. Marshall AC, Tworetzky W, Bergersen L, McElhinney DB, Benson CB, Jennings RW, Wilkins-Haug LE, Marx GR, Lock JE. Aortic valvuloplasty in the fetus: technical characteristics of successful balloon dilation. J Pediatr. 2005 Oct; 147(4):535-9.
  123. Wilkins-Haug LE, Benson CB, Tworetzky W, Marshall AC, Jennings RW, Lock JE. In-utero intervention for hypoplastic left heart syndrome--a perinatologist's perspective. Ultrasound Obstet Gynecol. 2005 Oct; 26(5):481-6.
  124. King A, Lock J, Xu G, Bonner-Weir S, Weir GC. Islet transplantation outcomes in mice are better with fresh islets and exendin-4 treatment. Diabetologia. 2005 Oct; 48(10):2074-9.
  125. McElhinney DB, Sherwood MC, Keane JF, del Nido PJ, Almond CS, Lock JE. Current management of severe congenital mitral stenosis: outcomes of transcatheter and surgical therapy in 108 infants and children. Circulation. 2005 Aug 2; 112(5):707-14.
  126. Lock J, Agras WS, Bryson S, Kraemer HC. A comparison of short- and long-term family therapy for adolescent anorexia nervosa. J Am Acad Child Adolesc Psychiatry. 2005 Jul; 44(7):632-9.
  127. Marshall AC, Lock JE. Leaving neverland: a randomized trial for coarctation shows pediatric interventional cardiology is growing up. Circulation. 2005 Jun 28; 111(25):3347-8.
  128. Bar-Cohen Y, Perry SB, Keane JF, Lock JE. Use of stents to maintain atrial defects and fontan fenestrations in congenital heart disease. J Interv Cardiol. 2005 Apr; 18(2):111-8.
  129. McElhinney DB, Lock JE, Keane JF, Moran AM, Colan SD. Left heart growth, function, and reintervention after balloon aortic valvuloplasty for neonatal aortic stenosis. Circulation. 2005 Feb 1; 111(4):451-8.
  130. Tworetzky W, Wilkins-Haug L, Jennings RW, van der Velde ME, Marshall AC, Marx GR, Colan SD, Benson CB, Lock JE, Perry SB. Balloon dilation of severe aortic stenosis in the fetus: potential for prevention of hypoplastic left heart syndrome: candidate selection, technique, and results of successful intervention. Circulation. 2004 Oct 12; 110(15):2125-31.
  131. Knauth AL, Lock JE, Perry SB, McElhinney DB, Gauvreau K, Landzberg MJ, Rome JJ, Hellenbrand WE, Ruiz CE, Jenkins KJ. Transcatheter device closure of congenital and postoperative residual ventricular septal defects. Circulation. 2004 Aug 3; 110(5):501-7.
  132. Marshall AC, van der Velde ME, Tworetzky W, Gomez CA, Wilkins-Haug L, Benson CB, Jennings RW, Lock JE. Creation of an atrial septal defect in utero for fetuses with hypoplastic left heart syndrome and intact or highly restrictive atrial septum. Circulation. 2004 Jul 20; 110(3):253-8.
  133. Hopkinson RA, Lock J. Athletics, perfectionism, and disordered eating. Eat Weight Disord. 2004 Jun; 9(2):99-106.
  134. Vlahos AP, Lock JE, McElhinney DB, van der Velde ME. Hypoplastic left heart syndrome with intact or highly restrictive atrial septum: outcome after neonatal transcatheter atrial septostomy. Circulation. 2004 May 18; 109(19):2326-30.
  135. Agras WS, Brandt HA, Bulik CM, Dolan-Sewell R, Fairburn CG, Halmi KA, Herzog DB, Jimerson DC, Kaplan AS, Kaye WH, le Grange D, Lock J, Mitchell JE, Rudorfer MV, Street LL, Striegel-Moore R, Vitousek KM, Walsh BT, Wilfley DE. Report of the National Institutes of Health workshop on overcoming barriers to treatment research in anorexia nervosa. Int J Eat Disord. 2004 May; 35(4):509-21.
  136. Geva T, Sandweiss BM, Gauvreau K, Lock JE, Powell AJ. Factors associated with impaired clinical status in long-term survivors of tetralogy of Fallot repair evaluated by magnetic resonance imaging. J Am Coll Cardiol. 2004 Mar 17; 43(6):1068-74.
  137. Marshall AC, Love BA, Lang P, Jonas RA, del Nido PJ, Mayer JE, Lock JE. Staged repair of tetralogy of Fallot and diminutive pulmonary arteries with a fenestrated ventricular septal defect patch. J Thorac Cardiovasc Surg. 2003 Nov; 126(5):1427-33.
  138. Siwik ES, Perry SB, Lock JE. Endovascular stent implantation in patients with stenotic aortoarteriopathies: early and medium-term results. Catheter Cardiovasc Interv. 2003 Jul; 59(3):380-6.
  139. Strauss A, Lock JE. Pediatric cardiomyopathy--a long way to go. N Engl J Med. 2003 Apr 24; 348(17):1703-5.
  140. O'Donnell CP, Lock JE, Powell AJ, Perry SB. Compression of pulmonary veins between the left atrium and the descending aorta. Am J Cardiol. 2003 Jan 15; 91(2):248-51.
  141. Bergersen LJ, Perry SB, Lock JE. Effect of cutting balloon angioplasty on resistant pulmonary artery stenosis. Am J Cardiol. 2003 Jan 15; 91(2):185-9.
  142. Meier B, Lock JE. Contemporary management of patent foramen ovale. Circulation. 2003 Jan 7; 107(1):5-9.
  143. Rome ES, Ammerman S, Rosen DS, Keller RJ, Lock J, Mammel KA, O'Toole J, Rees JM, Sanders MJ, Sawyer SM, Schneider M, Sigel E, Silber TJ. Children and adolescents with eating disorders: the state of the art. Pediatrics. 2003 Jan; 111(1):e98-108.
  144. Van Praagh S, Geva T, Lock JE, Nido PJ, Vance MS, Van Praagh R. Biatrial or left atrial drainage of the right superior vena cava: anatomic, morphogenetic, and surgical considerations--report of three new cases and literature review. Pediatr Cardiol. 2003 Jul-Aug; 24(4):350-63.
  145. Rosales AM, Lock JE, Perry SB, Geggel RL. Interventional catheterization management of perioperative peripheral pulmonary stenosis: balloon angioplasty or endovascular stenting. Catheter Cardiovasc Interv. 2002 Jun; 56(2):272-7.
  146. Armsby LR, Keane JF, Sherwood MC, Forbess JM, Perry SB, Lock JE. Management of coronary artery fistulae. Patient selection and results of transcatheter closure. J Am Coll Cardiol. 2002 Mar 20; 39(6):1026-32.
  147. Stamm C, Friehs I, Zurakowski D, Scheule AM, Moran AM, Lock JE, Mayer JE, del Nido PJ, Jonas RA. Outcome after reconstruction of discontinuous pulmonary arteries. J Thorac Cardiovasc Surg. 2002 Feb; 123(2):246-57.
  148. Huang T, Lock JE, Marshall AC, Basson C, Seidman JG, Seidman CE. Causes of clinical diversity in human TBX5 mutations. Cold Spring Harb Symp Quant Biol. 2002; 67:115-20.
  149. Powell AJ, Gauvreau K, Jenkins KJ, Blume ED, Mayer JE, Lock JE. Perioperative risk factors for development of protein-losing enteropathy following a Fontan procedure. Am J Cardiol. 2001 Nov 15; 88(10):1206-9.
  150. Zelenko MA, Huffman LC, Brown BW, Daniels K, Lock J, Kennedy Q, Steiner H. The Child Abuse Potential Inventory and pregnancy outcome in expectant adolescent mothers. Child Abuse Negl. 2001 Nov; 25(11):1481-95.
  151. Geggel RL, Gauvreau K, Lock JE. Balloon dilation angioplasty of peripheral pulmonary stenosis associated with Williams syndrome. Circulation. 2001 May 1; 103(17):2165-70.
  152. Grey ST, Lock J, Bach FH, Ferran C. Adenovirus-mediated gene transfer of A20 in murine islets inhibits Fas-induced apoptosis. Transplant Proc. 2001 Feb-Mar; 33(1-2):577-8.
  153. Feinstein JA, Goldhaber SZ, Lock JE, Ferndandes SM, Landzberg MJ. Balloon pulmonary angioplasty for treatment of chronic thromboembolic pulmonary hypertension. Circulation. 2001 Jan 2; 103(1):10-3.
  154. Stamm C, Friehs I, Mayer JE, Zurakowski D, Triedman JK, Moran AM, Walsh EP, Lock JE, Jonas RA. Long-term results of the lateral tunnel Fontan operation. J Thorac Cardiovasc Surg. 2001 Jan; 121(1):28-41.
  155. Lock J, Reisel B, Steiner H. Associated health risks of adolescents with disordered eating: how different are they from their peers? Results from a high school survey. Child Psychiatry Hum Dev. 2001; 31(3):249-65.
  156. Lock J, Le Grange D. Can family-based treatment of anorexia nervosa be manualized? J Psychother Pract Res. 2001; 10(4):253-61.
  157. Powell AJ, Mayer JE, Lang P, Lock JE. Outcome in infants with pulmonary atresia, intact ventricular septum, and right ventricle-dependent coronary circulation. Am J Cardiol. 2000 Dec 1; 86(11):1272-4, A9.
  158. Freedom RM, Lock J, Bricker JT. Pediatric cardiology and cardiovascular surgery: 1950-2000. Circulation. 2000 Nov 14; 102(20 Suppl 4):IV58-68.
  159. Baker CM, McGowan FX, Keane JF, Lock JE. Pulmonary artery trauma due to balloon dilation: recognition, avoidance and management. J Am Coll Cardiol. 2000 Nov 1; 36(5):1684-90.
  160. Goff DA, Blume ED, Gauvreau K, Mayer JE, Lock JE, Jenkins KJ. Clinical outcome of fenestrated Fontan patients after closure: the first 10 years. Circulation. 2000 Oct 24; 102(17):2094-9.
  161. Marshall AC, Lock JE. Structural and compliant anatomy of the patent foramen ovale in patients undergoing transcatheter closure. Am Heart J. 2000 Aug; 140(2):303-7.
  162. Zelenko M, Lock J, Kraemer HC, Steiner H. Perinatal complications and child abuse in a poverty sample. Child Abuse Negl. 2000 Jul; 24(7):939-50.
  163. Marshall AC, Perry SB, Keane JF, Lock JE. Early results and medium-term follow-up of stent implantation for mild residual or recurrent aortic coarctation. Am Heart J. 2000 Jun; 139(6):1054-60.
  164. Perry YY, Triedman JK, Gauvreau K, Lock JE, Jenkins KJ. Sudden death in patients after transcatheter device implantation for congenital heart disease. Am J Cardiol. 2000 Apr 15; 85(8):992-5.
  165. Hung J, Landzberg MJ, Jenkins KJ, King ME, Lock JE, Palacios IF, Lang P. Closure of patent foramen ovale for paradoxical emboli: intermediate-term risk of recurrent neurological events following transcatheter device placement. J Am Coll Cardiol. 2000 Apr; 35(5):1311-6.
  166. Lock JE. Patent foramen ovale is indicted, but the case hasn't gone to trial. Circulation. 2000 Feb 29; 101(8):838.
  167. Kreutzer J, Ryan CA, Wright JA, Jenkins KJ, Marx G, Van Praagh R, Lock JE. Acute animal studies of the STARFlex system: a new self-centering cardioSEAL septal occluder. Catheter Cardiovasc Interv. 2000 Feb; 49(2):225-33.
  168. Hausdorf G, Kaulitz R, Paul T, Carminati M, Lock J. Transcatheter closure of atrial septal defect with a new flexible, self-centering device (the STARFlex Occluder). Am J Cardiol. 1999 Nov 1; 84(9):1113-6, A10.
  169. Satou GM, Perry SB, Lock JE, Piercey GE, Keane JF. Repeat balloon dilation of congenital valvar aortic stenosis: immediate results and midterm outcome. Catheter Cardiovasc Interv. 1999 May; 47(1):47-51.
  170. Ambrosini PJ, Wagner KD, Biederman J, Glick I, Tan C, Elia J, Hebeler JR, Rabinovich H, Lock J, Geller D. Multicenter open-label sertraline study in adolescent outpatients with major depression. J Am Acad Child Adolesc Psychiatry. 1999 May; 38(5):566-72.
  171. Lock JE. Invited letter concerning surgical repair of recurrent aortic coarctation. J Thorac Cardiovasc Surg. 1999 Apr; 117(4):844-5.
  172. Atz AM, Adatia I, Lock JE, Wessel DL. Combined effects of nitric oxide and oxygen during acute pulmonary vasodilator testing. J Am Coll Cardiol. 1999 Mar; 33(3):813-9.
  173. Lock J, Steiner H. Gay, lesbian, and bisexual youth risks for emotional, physical, and social problems: results from a community-based survey. J Am Acad Child Adolesc Psychiatry. 1999 Mar; 38(3):297-304.
  174. Lock J, Walsh M. Development and implementation of depression care along the health care continuum. J Nurs Care Qual. 1999 Feb; 13(3):13-22.
  175. Lock J, Walsh M. Care management in a primary care depression team. Pilot project yields changes in treatment. Aspens Advis Nurse Exec. 1998 Aug; 13(11):7-10.
  176. Jonas RA, Keane JF, Lock JE. Aortic valve-preserving procedure for enlargement of the left ventricular outflow tract and mitral anulus. J Thorac Cardiovasc Surg. 1998 May; 115(5):1219-22.
  177. Landzberg MJ, Lock JE. Transcatheter management of ventricular septal rupture after myocardial infarction. Semin Thorac Cardiovasc Surg. 1998 Apr; 10(2):128-32.
  178. Steiner H, Lock J. Anorexia nervosa and bulimia nervosa in children and adolescents: a review of the past 10 years. J Am Acad Child Adolesc Psychiatry. 1998 Apr; 37(4):352-9.
  179. Gentles TL, Mayer JE, Gauvreau K, Newburger JW, Lock JE, Kupferschmid JP, Burnett J, Jonas RA, Castañeda AR, Wernovsky G. Fontan operation in five hundred consecutive patients: factors influencing early and late outcome. J Thorac Cardiovasc Surg. 1997 Sep; 114(3):376-91.
  180. Adatia I, Moore PM, Jonas RA, Colan SD, Lock JE, Keane JF. Clinical course and hemodynamic observations after supraannular mitral valve replacement in infants and children. J Am Coll Cardiol. 1997 Apr; 29(5):1089-94.
  181. Kumar K, Lock JE, Geva T. Apical muscular ventricular septal defects between the left ventricle and the right ventricular infundibulum. Diagnostic and interventional considerations. Circulation. 1997 Mar 4; 95(5):1207-13.
  182. Egito ES, Moore P, O'Sullivan J, Colan S, Perry SB, Lock JE, Keane JF. Transvascular balloon dilation for neonatal critical aortic stenosis: early and midterm results. J Am Coll Cardiol. 1997 Feb; 29(2):442-7.
  183. Kreutzer J, Lock JE, Jonas RA, Keane JF. Transcatheter fenestration dilation and/or creation in postoperative Fontan patients. Am J Cardiol. 1997 Jan 15; 79(2):228-32.
  184. Triedman JK, Jenkins KJ, Colan SD, Van Praagh R, Lock JE, Walsh EP. Multipolar endocardial mapping of the right heart using a basket catheter: acute and chronic animal studies. Pacing Clin Electrophysiol. 1997 Jan; 20(1 Pt 1):51-9.
  185. Hornberger LK, Colan SD, Lock JE, Wessel DL, Mayer JE. Outcome of patients with ectopia cordis and significant intracardiac defects. Circulation. 1996 Nov 1; 94(9 Suppl):II32-7.
  186. Kreutzer J, Perry SB, Jonas RA, Mayer JE, Castañeda AR, Lock JE. Tetralogy of Fallot with diminutive pulmonary arteries: preoperative pulmonary valve dilation and transcatheter rehabilitation of pulmonary arteries. J Am Coll Cardiol. 1996 Jun; 27(7):1741-7.
  187. Kreutzer J, Keane JF, Lock JE, Walsh EP, Jonas RA, Castañeda AR, Mayer JE. Conversion of modified Fontan procedure to lateral atrial tunnel cavopulmonary anastomosis. J Thorac Cardiovasc Surg. 1996 Jun; 111(6):1169-76.
  188. Kreutzer J, Landzberg MJ, Preminger TJ, Mandell VS, Treves ST, Reid LM, Lock JE. Isolated peripheral pulmonary artery stenoses in the adult. Circulation. 1996 Apr 1; 93(7):1417-23.
  189. Moore P, Egito E, Mowrey H, Perry SB, Lock JE, Keane JF. Midterm results of balloon dilation of congenital aortic stenosis: predictors of success. J Am Coll Cardiol. 1996 Apr; 27(5):1257-63.
  190. Powell AJ, Lock JE, Keane JF, Perry SB. Prolongation of RV-PA conduit life span by percutaneous stent implantation. Intermediate-term results. Circulation. 1995 Dec 1; 92(11):3282-8.
  191. Landzberg MJ, Sloss LJ, Faherty CE, Morrison BJ, Bittl JA, Bridges ND, Casale PN, Keane JF, Lock JE. Orthodeoxia-platypnea due to intracardiac shunting--relief with transcatheter double umbrella closure. Cathet Cardiovasc Diagn. 1995 Nov; 36(3):247-50.
  192. Srivastava D, Preminger T, Lock JE, Mandell V, Keane JF, Mayer JE, Kozakewich H, Spevak PJ. Hepatic venous blood and the development of pulmonary arteriovenous malformations in congenital heart disease. Circulation. 1995 Sep 1; 92(5):1217-22.
  193. Bridges ND, Lock JE, Mayer JE, Burnett J, Castaneda AR. Cardiac catheterization and test occlusion of the interatrial communication after the fenestrated Fontan operation. J Am Coll Cardiol. 1995 Jun; 25(7):1712-7.
  194. Laussen PC, Hansen DD, Perry SB, Fox ML, Javorski JJ, Burrows FA, Lock JE, Hickey PR. Transcatheter closure of ventricular septal defects: hemodynamic instability and anesthetic management. Anesth Analg. 1995 Jun; 80(6):1076-82.
  195. Verma R, Lock BG, Perry SB, Moore P, Keane JF, Lock JE. Intraaortic spring coil loops: early and late results. J Am Coll Cardiol. 1995 May; 25(6):1416-9.
  196. du Plessis AJ, Chang AC, Wessel DL, Lock JE, Wernovsky G, Newburger JW, Mayer JE. Cerebrovascular accidents following the Fontan operation. Pediatr Neurol. 1995 Apr; 12(3):230-6.
  197. Jenkins KJ, Newburger JW, Lock JE, Davis RB, Coffman GA, Iezzoni LI. In-hospital mortality for surgical repair of congenital heart defects: preliminary observations of variation by hospital caseload. Pediatrics. 1995 Mar; 95(3):323-30.
  198. Rosenfeld HM, van der Velde ME, Sanders SP, Colan SD, Parness IA, Lock JE, Spevak PJ. Echocardiographic predictors of candidacy for successful transcatheter atrial septal defect closure. Cathet Cardiovasc Diagn. 1995 Jan; 34(1):29-34.
  199. Colli AM, Perry SB, Lock JE, Keane JF. Balloon dilation of critical valvar pulmonary stenosis in the first month of life. Cathet Cardiovasc Diagn. 1995 Jan; 34(1):23-8.
  200. Laham RJ, Ho KK, Douglas PS, Faherty CE, Lock JE, Baim DS, Kuntz RE. Right ventricular infarction complicated by acute right-to-left shunting. Am J Cardiol. 1994 Oct 15; 74(8):824-6.
  201. van der Velde ME, Sanders SP, Keane JF, Perry SB, Lock JE. Transesophageal echocardiographic guidance of transcatheter ventricular septal defect closure. J Am Coll Cardiol. 1994 Jun; 23(7):1660-5.
  202. Rosenfeld HM, Landzberg MJ, Perry SB, Colan SD, Keane JF, Lock JE. Balloon aortic valvuloplasty in the young adult with congenital aortic stenosis. Am J Cardiol. 1994 Jun 1; 73(15):1112-7.
  203. Moore P, Adatia I, Spevak PJ, Keane JF, Perry SB, Castaneda AR, Lock JE. Severe congenital mitral stenosis in infants. Circulation. 1994 May; 89(5):2099-106.
  204. Preminger TJ, Lock JE, Perry SB. Traumatic aortopulmonary window as a complication of pulmonary artery balloon angioplasty: transcatheter occlusion with a covered stent. A case report. Cathet Cardiovasc Diagn. 1994 Apr; 31(4):286-9.
  205. Chang AC, Hanley FL, Lock JE, Castaneda AR, Wessel DL. Management and outcome of low birth weight neonates with congenital heart disease. J Pediatr. 1994 Mar; 124(3):461-6.
  206. Preminger TJ, Sanders SP, van der Velde ME, Castañeda AR, Lock JE. "Intramural" residual interventricular defects after repair of conotruncal malformations. Circulation. 1994 Jan; 89(1):236-42.
  207. Spevak PJ, Mandell VS, Colan SD, Van Der Velde ME, Jonas RA, Lock JE, Sanders SP. Reliability of Doppler color flow mapping in the identification and localization of multiple ventricular septal defects. Echocardiography. 1993 Nov; 10(6):573-81.
  208. Fishberger SB, Bridges ND, Keane JF, Hanley FL, Jonas RA, Mayer JE, Castaneda AR, Lock JE. Intraoperative device closure of ventricular septal defects. Circulation. 1993 Nov; 88(5 Pt 2):II205-9.
  209. Giglia TM, Jenkins KJ, Matitiau A, Mandell VS, Sanders SP, Mayer JE, Lock JE. Influence of right heart size on outcome in pulmonary atresia with intact ventricular septum. Circulation. 1993 Nov; 88(5 Pt 1):2248-56.
  210. Chang AC, Hanley FL, Wernovsky G, Rosenfeld HM, Wessel DL, Jonas RA, Mayer JE, Lock JE, Castaneda AR. Early bidirectional cavopulmonary shunt in young infants. Postoperative course and early results. Circulation. 1993 Nov; 88(5 Pt 2):II149-58.
  211. Landzberg MJ, Lock JE. Interventional catheter procedures used in congenital heart disease. Cardiol Clin. 1993 Nov; 11(4):569-87.
  212. Rome JJ, Mayer JE, Castaneda AR, Lock JE. Tetralogy of Fallot with pulmonary atresia. Rehabilitation of diminutive pulmonary arteries. Circulation. 1993 Oct; 88(4 Pt 1):1691-8.
  213. Jenkins KJ, Walsh EP, Colan SD, Bergau DM, Saul JP, Lock JE. Multipolar endocardial mapping of the right atrium during cardiac catheterization: description of a new technique. J Am Coll Cardiol. 1993 Oct; 22(4):1105-10.
  214. Gentles TL, Lock JE, Perry SB. High pressure balloon angioplasty for branch pulmonary artery stenosis: early experience. J Am Coll Cardiol. 1993 Sep; 22(3):867-72.
  215. O'Laughlin MP, Slack MC, Grifka RG, Perry SB, Lock JE, Mullins CE. Implantation and intermediate-term follow-up of stents in congenital heart disease. Circulation. 1993 Aug; 88(2):605-14.
  216. Triedman JK, Bridges ND, Mayer JE, Lock JE. Prevalence and risk factors for aortopulmonary collateral vessels after Fontan and bidirectional Glenn procedures. J Am Coll Cardiol. 1993 Jul; 22(1):207-15.
  217. Rein AJ, Preminger TJ, Perry SB, Lock JE, Sanders SP. Generalized arteriopathy in Williams syndrome: an intravascular ultrasound study. J Am Coll Cardiol. 1993 Jun; 21(7):1727-30.
  218. Perry SB, van der Velde ME, Bridges ND, Keane JF, Lock JE. Transcatheter closure of atrial and ventricular septal defects. Herz. 1993 Apr; 18(2):135-42.
  219. Saul JP, Hulse JE, De W, Weber AT, Rhodes LA, Lock JE, Walsh EP. Catheter ablation of accessory atrioventricular pathways in young patients: use of long vascular sheaths, the transseptal approach and a retrograde left posterior parallel approach. J Am Coll Cardiol. 1993 Mar 1; 21(3):571-83.
  220. Landzberg MJ, Lock JE. Transcatheter closure of cardiac defects. Adv Pediatr. 1993; 40:247-71.
  221. Bridges ND, Hellenbrand W, Latson L, Filiano J, Newburger JW, Lock JE. Transcatheter closure of patent foramen ovale after presumed paradoxical embolism. Circulation. 1992 Dec; 86(6):1902-8.
  222. Bridges ND, Mayer JE, Lock JE, Jonas RA, Hanley FL, Keane JF, Perry SB, Castaneda AR. Effect of baffle fenestration on outcome of the modified Fontan operation. Circulation. 1992 Dec; 86(6):1762-9.
  223. Hourihan M, Perry SB, Mandell VS, Keane JF, Rome JJ, Bittl JA, Lock JE. Transcatheter umbrella closure of valvular and paravalvular leaks. J Am Coll Cardiol. 1992 Nov 15; 20(6):1371-7.
  224. Giglia TM, Mandell VS, Connor AR, Mayer JE, Lock JE. Diagnosis and management of right ventricle-dependent coronary circulation in pulmonary atresia with intact ventricular septum. Circulation. 1992 Nov; 86(5):1516-28.
  225. Wong PC, Barlow CF, Hickey PR, Jonas RA, Castaneda AR, Farrell DM, Lock JE, Wessel DL. Factors associated with choreoathetosis after cardiopulmonary bypass in children with congenital heart disease. Circulation. 1992 Nov; 86(5 Suppl):II118-26.
  226. Walsh EP, Saul JP, Hulse JE, Rhodes LA, Hordof AJ, Mayer JE, Lock JE. Transcatheter ablation of ectopic atrial tachycardia in young patients using radiofrequency current. Circulation. 1992 Oct; 86(4):1138-46.
  227. Perry SB, Lock JE. Front-loading of double-umbrella devices, a new technique for umbrella delivery for closing cardiovascular defects. Am J Cardiol. 1992 Oct 1; 70(9):917-20.
  228. Perry SB, Rome J, Keane JF, Baim DS, Lock JE. Transcatheter closure of coronary artery fistulas. J Am Coll Cardiol. 1992 Jul; 20(1):205-9.
  229. Triedman JK, Perry SB, van der Velde ME, Lock JE. Closure of congenital and acquired intracardiac shunts using transcatheter techniques: a review. Indian Heart J. 1992 May-Jun; 44(3):125-31.
  230. Mayer JE, Bridges ND, Lock JE, Hanley FL, Jonas RA, Castaneda AR. Factors associated with marked reduction in mortality for Fontan operations in patients with single ventricle. J Thorac Cardiovasc Surg. 1992 Mar; 103(3):444-51; discussion 451-2.
  231. Marin-Garcia J, Lock JE. Catheter embolization of pulmonary arteriovenous fistulas in an infant. Pediatr Cardiol. 1992 Jan; 13(1):41-3.
  232. van der Velde ME, Parness IA, Colan SD, Spevak PJ, Lock JE, Mayer JE, Sanders SP. Two-dimensional echocardiography in the pre- and postoperative management of totally anomalous pulmonary venous connection. J Am Coll Cardiol. 1991 Dec; 18(7):1746-51.
  233. Bridges ND, Perry SB, Parness I, Keane JF, Lock JE. Transcatheter closure of a large patent ductus arteriosus with the clamshell septal umbrella. J Am Coll Cardiol. 1991 Nov 1; 18(5):1297-302.
  234. Lock JE. The adult with congenital heart disease: cardiac catheterization as a therapeutic intervention. J Am Coll Cardiol. 1991 Aug; 18(2):330-1.
  235. O'Laughlin MP, Perry SB, Lock JE, Mullins CE. Use of endovascular stents in congenital heart disease. Circulation. 1991 Jun; 83(6):1923-39.
  236. Bridges ND, Perry SB, Keane JF, Goldstein SA, Mandell V, Mayer JE, Jonas RA, Casteneda AR, Lock JE. Preoperative transcatheter closure of congenital muscular ventricular septal defects. N Engl J Med. 1991 May 9; 324(19):1312-7.
  237. Flanagan MF, Fujii AM, Colan SD, Flanagan RG, Lock JE. Myocardial angiogenesis and coronary perfusion in left ventricular pressure-overload hypertrophy in the young lamb. Evidence for inhibition with chronic protamine administration. Circ Res. 1991 May; 68(5):1458-70.
  238. Bridges ND, Lock JE, Castaneda AR. Baffle fenestration with subsequent transcatheter closure. Modification of the Fontan operation for patients at increased risk. Circulation. 1990 Nov; 82(5):1681-9.
  239. Rome JJ, Keane JF, Perry SB, Spevak PJ, Lock JE. Double-umbrella closure of atrial defects. Initial clinical applications. Circulation. 1990 Sep; 82(3):751-8.
  240. Spevak PJ, Bass JL, Ben-Shachar G, Hesslein P, Keane JF, Perry S, Pyles L, Lock JE. Balloon angioplasty for congenital mitral stenosis. Am J Cardiol. 1990 Aug 15; 66(4):472-6.
  241. Keane JF, Perry SB, Lock JE. Balloon dilation of congenital valvular aortic stenosis. J Am Coll Cardiol. 1990 Aug; 16(2):457-8.
  242. Johnson WH, Peterson RK, Howland DF, Lock JE. Systemic heparinization does not prevent clot formation in coil embolization. Cathet Cardiovasc Diagn. 1990 Aug; 20(4):267-70.
  243. Mandell VS, Lock JE, Mayer JE, Parness IA, Kulik TJ. The "laid-back" aortogram: an improved angiographic view for demonstration of coronary arteries in transposition of the great arteries. Am J Cardiol. 1990 Jun 1; 65(20):1379-83.
  244. Rothman A, Perry SB, Keane JF, Lock JE. Early results and follow-up of balloon angioplasty for branch pulmonary artery stenoses. J Am Coll Cardiol. 1990 Apr; 15(5):1109-17.
  245. Radtke W, Lock J. Balloon dilation catheters. Pediatr Clin North Am. 1990 Feb; 37(1):193-213.
  246. Rothman A, Perry SB, Keane JF, Lock JE. Balloon dilation of branch pulmonary artery stenosis. Semin Thorac Cardiovasc Surg. 1990 Jan; 2(1):46-54.
  247. Castaneda AR, Mayer JE, Jonas RA, Lock JE, Wessel DL, Hickey PR. The neonate with critical congenital heart disease: repair--a surgical challenge. J Thorac Cardiovasc Surg. 1989 Nov; 98(5 Pt 2):869-75.
  248. Zeevi B, Keane JF, Castaneda AR, Perry SB, Lock JE. Neonatal critical valvar aortic stenosis. A comparison of surgical and balloon dilation therapy. Circulation. 1989 Oct; 80(4):831-9.
  249. Zeevi B, Keane JF, Perry SB, Lock JE. Balloon dilation of postoperative right ventricular outflow obstructions. J Am Coll Cardiol. 1989 Aug; 14(2):401-8; discussion 409-12.
  250. Lock JE, Rome JJ, Davis R, Van Praagh S, Perry SB, Van Praagh R, Keane JF. Transcatheter closure of atrial septal defects. Experimental studies. Circulation. 1989 May; 79(5):1091-9.
  251. Perry SB, Zeevi B, Keane JF, Lock JE. Interventional catheterization of left heart lesions, including aortic and mitral valve stenosis and coarctation of the aorta. Cardiol Clin. 1989 May; 7(2):341-9.
  252. Lock JE. Enlargeable prosthesis for banding the main pulmonary artery. J Thorac Cardiovasc Surg. 1989 Mar; 97(3):473.
  253. Perry SB, Radtke W, Fellows KE, Keane JF, Lock JE. Coil embolization to occlude aortopulmonary collateral vessels and shunts in patients with congenital heart disease. J Am Coll Cardiol. 1989 Jan; 13(1):100-8.
  254. Vita JA, Bittl JA, Selwyn AP, Lock JE. Transcatheter closure of a calcified patent ductus arteriosus in an elderly man. J Am Coll Cardiol. 1988 Nov; 12(5):1382-5.
  255. Zeevi B, Perry SB, Keane JF, Mandell VS, Lock JE. Interventional cardiac procedures in neonates and infants: state of the art. Clin Perinatol. 1988 Sep; 15(3):633-58.
  256. Sholler GF, Keane JF, Perry SB, Sanders SP, Lock JE. Balloon dilation of congenital aortic valve stenosis. Results and influence of technical and morphological features on outcome. Circulation. 1988 Aug; 78(2):351-60.
  257. Lock JE, Block PC, McKay RG, Baim DS, Keane JF. Transcatheter closure of ventricular septal defects. Circulation. 1988 Aug; 78(2):361-8.
  258. Arnold LW, Keane JF, Kan JS, Fellows KE, Lock JE. Transient unilateral pulmonary edema after successful balloon dilation of peripheral pulmonary artery stenosis. Am J Cardiol. 1988 Aug 1; 62(4):327-30.
  259. Lucas RV, Lock JE, Tandon R, Edwards JE. Gross and histologic anatomy of total anomalous pulmonary venous connections. Am J Cardiol. 1988 Aug 1; 62(4):292-300.
  260. Perry SB, Keane JF, Lock JE. Interventional catheterization in pediatric congenital and acquired heart disease. Am J Cardiol. 1988 May 9; 61(14):109G-117G.
  261. Walsh EP, Rockenmacher S, Keane JF, Hougen TJ, Lock JE, Castaneda AR. Late results in patients with tetralogy of Fallot repaired during infancy. Circulation. 1988 May; 77(5):1062-7.
  262. Wessel DL, Keane JF, Parness I, Lock JE. Outpatient closure of the patent ductus arteriosus. Circulation. 1988 May; 77(5):1068-71.
  263. Zeevi B, Keane JF, Fellows KE, Lock JE. Balloon dilation of critical pulmonary stenosis in the first week of life. J Am Coll Cardiol. 1988 Apr; 11(4):821-4.
  264. Rome JJ, Lock JE. New developments in pediatric interventional heart catheterization. G Ital Cardiol. 1988 Apr; 18(4):255-8.
  265. Lipshultz SE, Sanders SP, Mayer JE, Colan SD, Lock JE. Are routine preoperative cardiac catheterization and angiography necessary before repair of ostium primum atrial septal defect? J Am Coll Cardiol. 1988 Feb; 11(2):373-8.
  266. Kulik TJ, Johnson DE, Elde RP, Lock JE. Pulmonary and systemic vascular effects of serotonin in conscious newborn lambs. Dev Pharmacol Ther. 1988; 11(3):135-41.
  267. Fellows KE, Radtke W, Keane JF, Lock JE. Acute complications of catheter therapy for congenital heart disease. Am J Cardiol. 1987 Sep 15; 60(8):679-83.
  268. Mietus-Snyder M, Lang P, Mayer JE, Jones RA, Castaneda AR, Lock JE. Childhood systemic-pulmonary shunts: subsequent suitability for Fontan operation. Circulation. 1987 Sep; 76(3 Pt 2):III39-44.
  269. Rothman A, Lang P, Lock JE, Jonas RA, Mayer JE, Castaneda AR. Surgical management of subaortic obstruction in single left ventricle and tricuspid atresia. J Am Coll Cardiol. 1987 Aug; 10(2):421-6.
  270. Kulik TJ, Lock JE. Leukotrienes and the immature pulmonary circulation. Am Rev Respir Dis. 1987 Jul; 136(1):220-2.
  271. Saul JP, Keane JF, Fellows KE, Lock JE. Balloon dilation angioplasty of postoperative aortic obstructions. Am J Cardiol. 1987 Apr 15; 59(9):943-8.
  272. Helgason H, Keane JF, Fellows KE, Kulik TJ, Lock JE. Balloon dilation of the aortic valve: studies in normal lambs and in children with aortic stenosis. J Am Coll Cardiol. 1987 Apr; 9(4):816-22.
  273. McKay RG, Lock JE, Safian RD, Come PC, Diver DJ, Baim DS, Berman AD, Warren SE, Mandell VE, Royal HD, et al. Balloon dilation of mitral stenosis in adult patients: postmortem and percutaneous mitral valvuloplasty studies. J Am Coll Cardiol. 1987 Apr; 9(4):723-31.
  274. Lock JE, Cockerham JT, Keane JF, Finley JP, Wakely PE, Fellows KE. Transcatheter umbrella closure of congenital heart defects. Circulation. 1987 Mar; 75(3):593-9.
  275. Nancarrow PA, Fellows KE, Lock JE. Stability of coil emboli: an in vitro study. Cardiovasc Intervent Radiol. 1987; 10(4):226-9.
  276. McKay RG, Safian RD, Lock JE, Diver DJ, Berman AD, Warren SE, Come PC, Baim DS, Mandell VE, Royal HD, et al. Assessment of left ventricular and aortic valve function after aortic balloon valvuloplasty in adult patients with critical aortic stenosis. Circulation. 1987 Jan; 75(1):192-203.
  277. Radtke W, Keane JF, Fellows KE, Lang P, Lock JE. Percutaneous balloon valvotomy of congenital pulmonary stenosis using oversized balloons. J Am Coll Cardiol. 1986 Oct; 8(4):909-15.
  278. Perry SB, Lang P, Keane JF, Jonas RA, Sanders SP, Lock JE. Creation and maintenance of an adequate interatrial communication in left atrioventricular valve atresia or stenosis. Am J Cardiol. 1986 Sep 15; 58(7):622-6.
  279. Wessel DL, Keane JF, Fellows KE, Robichaud H, Lock JE. Fibrinolytic therapy for femoral arterial thrombosis after cardiac catheterization in infants and children. Am J Cardiol. 1986 Aug 1; 58(3):347-51.
  280. McKay RG, Safian RD, Lock JE, Mandell VS, Thurer RL, Schnitt SJ, Grossman W. Balloon dilatation of calcific aortic stenosis in elderly patients: postmortem, intraoperative, and percutaneous valvuloplasty studies. Circulation. 1986 Jul; 74(1):119-25.
  281. Palacios IF, Lock JE, Keane JF, Block PC. Percutaneous transvenous balloon valvotomy in a patient with severe calcific mitral stenosis. J Am Coll Cardiol. 1986 Jun; 7(6):1416-9.
  282. McKay RG, Lock JE, Keane JF, Safian RD, Aroesty JM, Grossman W. Percutaneous mitral valvuloplasty in an adult patient with calcific rheumatic mitral stenosis. J Am Coll Cardiol. 1986 Jun; 7(6):1410-5.
  283. Lock JE, Keane JF, Fellows KE. The use of catheter intervention procedures for congenital heart disease. J Am Coll Cardiol. 1986 Jun; 7(6):1420-3.
  284. Nancarrow PA, Lock JE, Fellows KE. Embolization of an intraosseous arteriovenous malformation. AJR Am J Roentgenol. 1986 Apr; 146(4):785-6.
  285. Fuhrman BP, Smith-Wright DL, Kulik TJ, Lock JE. Effects of static and fluctuating airway pressure on intact pulmonary circulation. J Appl Physiol (1985). 1986 Jan; 60(1):114-22.
  286. Flanagan MF, Leatherman GF, Carls A, Keane JF, Selwyn AP, Lock JE. Changing trends of congenital heart disease in adults: a catheterization laboratory perspective. Cathet Cardiovasc Diagn. 1986; 12(4):215-8.
  287. Lock JE, Khalilullah M, Shrivastava S, Bahl V, Keane JF. Percutaneous catheter commissurotomy in rheumatic mitral stenosis. N Engl J Med. 1985 Dec 12; 313(24):1515-8.
  288. Hoffer FA, Fellows KE, Wyly JB, Lock JE. Therapeutic catheter procedures in pediatrics. Pediatr Clin North Am. 1985 Dec; 32(6):1461-76.
  289. Kulik TJ, Schutjer RK, Howland DF, Lock JE. Pulmonary and systemic vascular effects of SRS-A blockade in conscious lambs. Am J Physiol. 1985 Nov; 249(5 Pt 2):H968-73.
  290. Keane JF, McFaul R, Fellows K, Lock J. Balloon occlusion angiography in infancy: methods, uses and limitations. Am J Cardiol. 1985 Sep 1; 56(7):495-7.
  291. Ring JC, Bass JL, Marvin W, Fuhrman BP, Kulik TJ, Foker JE, Lock JE. Management of congenital stenosis of a branch pulmonary artery with balloon dilation angioplasty. Report of 52 procedures. J Thorac Cardiovasc Surg. 1985 Jul; 90(1):35-44.
  292. Lock JE, Keane JF. Non-coronary balloon angioplasty. Indian Heart J. 1985 May-Jun; 37(3):142.
  293. Johnson DE, Kulik TJ, Lock JE, Elde RP, Thompson TR. Bombesin-, calcitonin-, and serotonin-immunoreactive pulmonary neuroendocrine cells in acute and chronic neonatal lung disease. Pediatr Pulmonol. 1985 May-Jun; 1(3 Suppl):S13-20.
  294. Lock JE, Bass JL, Lund G, Rysavy JA, Lucas RV. Transcatheter closure of patent ductus arteriosus in piglets. Am J Cardiol. 1985 Mar 1; 55(6):826-9.
  295. Edwards BS, Lucas RV, Lock JE, Edwards JE. Morphologic changes in the pulmonary arteries after percutaneous balloon angioplasty for pulmonary arterial stenosis. Circulation. 1985 Feb; 71(2):195-201.
  296. Ring JC, Kulik TJ, Burke BA, Lock JE. Morphologic changes induced by dilation of the pulmonary valve anulus with overlarge balloons in normal newborn lambs. Am J Cardiol. 1985 Jan 1; 55(1):210-4.
  297. Kulik TJ, Johnson DE, Lock JE. Pulmonary vascular effects of Leu5-enkephalin in conscious newborn lambs. Peptides. 1985 Jan-Feb; 6(1):1-5.
  298. Lock JE. Now that we can dilate, should we? Am J Cardiol. 1984 Dec 1; 54(10):1360.
  299. Gatto C, Johnson MG, Seybold V, Kulik TJ, Lock JE, Johnson DE. Distribution and quantitative developmental changes in guinea pig pulmonary beta-receptors. J Appl Physiol Respir Environ Exerc Physiol. 1984 Dec; 57(6):1901-7.
  300. Smith-Wright DL, Green TP, Lock JE, Egar MI, Fuhrman BP. Complications of vascular catheterization in critically ill children. Crit Care Med. 1984 Dec; 12(12):1015-7.
  301. Kulik TJ, Lock JE. Pulmonary vasodilator therapy in persistent pulmonary hypertension of the newborn. Clin Perinatol. 1984 Oct; 11(3):693-701.
  302. Lock JE, Bass JL, Castaneda-Zuniga W, Fuhrman BP, Rashkind WJ, Lucas RV. Dilation angioplasty of congenital or operative narrowings of venous channels. Circulation. 1984 Sep; 70(3):457-64.
  303. Fuhrman BP, Bass JL, Castaneda-Zuniga W, Amplatz K, Lock JE. Coil embolization of congenital thoracic vascular anomalies in infants and children. Circulation. 1984 Aug; 70(2):285-9.
  304. Fuhrman BP, Everitt J, Lock JE. Cardiopulmonary effects of unilateral airway pressure changes in intact infant lambs. J Appl Physiol Respir Environ Exerc Physiol. 1984 May; 56(5):1439-48.
  305. Kulik TJ, Johnson DE, Elde RP, Lock JE. Pulmonary vascular effects of vasoactive intestinal peptide in conscious newborn lambs. Am J Physiol. 1984 May; 246(5 Pt 2):H716-9.
  306. Lock JE, Bass JL, Kulik TJ, Fuhrman BP. Chronic percutaneous pericardial drainage with modified pigtail catheters in children. Am J Cardiol. 1984 Apr 1; 53(8):1179-82.
  307. Drummond WH, Lock JE. Neonatal 'pulmonary vasodilator' drugs. Current status. Dev Pharmacol Ther. 1984; 7(1):1-20.
  308. Kulik TJ, Lock JE. The assessment of pulmonary vascular tone: a review of experimental methodologies. Pediatr Pharmacol (New York). 1984; 4(2):73-83.
  309. Braunlin EA, Lock JE, Foker JE. Repair of type B interruption of the aortic arch. Results and follow-up. J Thorac Cardiovasc Surg. 1983 Dec; 86(6):920-5.
  310. Lock JE, Kulik TJ, Green TP, Niemi T, Einzig S. Resting and exercise renal blood flows in immature ovine aortic coarctation. Impact of gradient relief. Circ Res. 1983 Nov; 53(5):644-54.
  311. Bass JL, Fuhrman BP, Lock JE. Balloon occlusion of atrial septal defect to assess right ventricular capability in hypoplastic right heart syndrome. Circulation. 1983 Nov; 68(5):1081-6.
  312. Kulik TJ, Johnson DE, Elde RP, Lock JE. Pulmonary vascular effects of bombesin and gastrin-releasing peptide in conscious newborn lambs. J Appl Physiol Respir Environ Exerc Physiol. 1983 Oct; 55(4):1093-7.
  313. Green TP, Thompson TR, Johnson DE, Lock JE. Diuresis and pulmonary function in premature infants with respiratory distress syndrome. J Pediatr. 1983 Oct; 103(4):618-23.
  314. Mammel MC, Einzig S, Kulik TJ, Thompson TR, Lock JE. Pulmonary vascular effects of amrinone in conscious lambs. Pediatr Res. 1983 Sep; 17(9):720-4.
  315. Kulik TJ, Bass JL, Fuhrman BP, Moller JH, Lock JE. Exercise induced pulmonary vasoconstriction. Br Heart J. 1983 Jul; 50(1):59-64.
  316. Lock JE, Bass JL, Amplatz K, Fuhrman BP, Castaneda-Zuniga W. Balloon dilation angioplasty of aortic coarctations in infants and children. Circulation. 1983 Jul; 68(1):109-16.
  317. Lock JE, Castaneda-Zuniga WR, Fuhrman BP, Bass JL. Balloon dilation angioplasty of hypoplastic and stenotic pulmonary arteries. Circulation. 1983 May; 67(5):962-7.
  318. Green TP, Thompson TR, Johnson DE, Lock JE. Furosemide promotes patent ductus arteriosus in premature infants with the respiratory-distress syndrome. N Engl J Med. 1983 Mar 31; 308(13):743-8.
  319. Lock JE, Niemi T, Burke BA, Einzig S, Castaneda-Zuniga WR. Transcutaneous angioplasty of experimental aortic coarctation. Circulation. 1982 Dec; 66(6):1280-6.
  320. Herrera M, Castaneda-Zuniga WR, Rusnak BW, Lock JE, Amplatz K. Removal of partially extruded steel coils. Radiology. 1982 Aug; 144(3):644-5.
  321. Johnson DE, Lock JE, Elde RP, Thompson TR. Pulmonary neuroendocrine cells in hyaline membrane disease and bronchopulmonary dysplasia. Pediatr Res. 1982 Jun; 16(6):446-54.
  322. Lock JE, Castaneda-Zuniga WR, Bass JL, Foker JE, Amplatz K, Anderson RW. Balloon dilatation of excised aortic coarctations. Radiology. 1982 Jun; 143(3):689-91.
  323. Castaneda-Zuniga WR, Lock JE, Vlodaver Z, Rusnak B, Rysavy JP, Herrera M, Amplatz K. Transluminal dilatation of coarctation of the abdominal aorta. An experimental study in dogs. Radiology. 1982 Jun; 143(3):693-7.
  324. Shachar GB, Fuhrman BP, Wang Y, Lucas RV, Lock JE. Rest and exercise hemodynamics after the Fontan procedure. Circulation. 1982 Jun; 65(6):1043-8.
  325. Lock JE, Einzig S, Bass JL, Moller JH. The pulmonary vascular response to oxygen and its influence on operative results in children with ventricular septal defect. Pediatr Cardiol. 1982; 3(1):41-6.
  326. Lock JE, Niemi T, Einzig S, Amplatz K, Burke B, Bass JL. Transvenous angioplasty of experimental branch pulmonary artery stenosis in newborn lambs. Circulation. 1981 Nov; 64(5):886-93.
  327. Kulik TJ, Foker JE, Lucas RV, Anderson RW, Lock JE. Postoperative hemodynamics in children with polytetrafluoroethylene shunts. Circulation. 1981 Aug; 64(2 Pt 2):II123-30.
  328. Lock JE, Olley PM, Coceani F. Enhanced beta-adrenergic-receptor responsiveness in hypoxic neonatal pulmonary circulation. Am J Physiol. 1981 May; 240(5):H697-703.
  329. Green TP, Thompson TR, Johnson D, Lock JE. Furosemide use in premature infants and appearance of patent ductus arteriosus. Am J Dis Child. 1981 Mar; 135(3):239-43.
  330. Castaneda-Zuniga WR, Bass JL, Lock JE. Selective opacification of arteries with balloon-occlusion angiography. Radiology. 1981 Mar; 138(3):727-9.
  331. Loes MW, Lock JE, Singh S, Mirkin BL. The kinetics of red blood cell electrolyte alterations following digoxin administration. A report of two pediatric cases. Dev Pharmacol Ther. 1981; 3(1):50-4.
  332. Lock JE, Coceani F, Hamilton F, Greenaway-Coates A, Olley PM. The pulmonary vascular effects of three prostaglandin I2 analogs in conscious newborn lambs. J Pharmacol Exp Ther. 1980 Oct; 215(1):156-9.
  333. Green TP, Thompson TR, Johnson D, Lock JE. Fluid administration and the development of patent ductus arteriosus. N Engl J Med. 1980 Aug 7; 303(6):337.
  334. Lock JE, Olley PM, Soldin S, Coceani F. Indomethacin-induced pulmonary vasoconstriction in the conscious newborn lamb. Am J Physiol. 1980 May; 238(5):H639-51.
  335. Lock JE, Olley PM, Coceani F. Direct pulmonary vascular responses to prostaglandins in the conscious newborn lamb. Am J Physiol. 1980 May; 238(5):H631-8.
  336. Lock JE, Hamilton F, Olley PM, Coceani F. The effect of alveolar hypoxia on pulmonary vascular responsiveness in the conscious newborn lamb. Can J Physiol Pharmacol. 1980 Feb; 58(2):153-9.
  337. Lock JE, Coceani F, Olley PM. Pulmonary vascular responses to prostaglandins in the conscious newborn lamb. Adv Prostaglandin Thromboxane Res. 1980; 7:751-3.
  338. Lock JE, Hamilton F, Luide H, Coceani F, Olley PM. Direct pulmonary vascular responses in the conscious newborn lamb. J Appl Physiol Respir Environ Exerc Physiol. 1980 Jan; 48(1):188-96.
  339. Lock JE, Coceani F, Olley PM. Direct and indirect pulmonary vascular effects of tolazoline in the newborn lamb. J Pediatr. 1979 Oct; 95(4):600-5.
  340. Lock JE, Olley PM, Coceani F, Hamilton F, Doubilet G. Pulmonary and systemic vascular responses to 6-keto-PGE1 in the conscious lamb. Prostaglandins. 1979 Aug; 18(2):303-9.
  341. Lock JE, Olley PM, Coceani F, Swyer PR, Rowe RD. Use of prostacyclin in persistent fetal circulation. Lancet. 1979 Jun 23; 1(8130):1343.
  342. Loes MW, Singh S, Lock JE, Mirkin BL. Relation between plasma and red-cell electrolyte concentrations and digoxin levels in children. N Engl J Med. 1978 Sep 7; 299(10):501-4.
  343. Lock JE, Einzig S, Moller JH. Hemodynamic responses to exercise in normal children. Am J Cardiol. 1978 Jun; 41(7):1278-84.
  344. Lock JE, Lucas RV, Amplatz K, Bessinger FB. Silent unilateral pulmonary venous obstruction. Occurrence after surgical correction of transposition of the great arteries. Chest. 1978 Feb; 73(2):224-7.
  345. Lock JE, Lynch RE, Mauer SM. Metabolic alkalosis in children with congestive heart failure. J Pediatr. 1975 Dec; 87(6 Pt 1):938-40.
  346. Perry TL, Urquhart N, MacLean J, Evans ME, Hansen S, Davidson GF, Applegarth DA, MacLeod PJ, Lock JE. Nonketotic hyperglycinemia. Glycine accumulation due to absence of glycerine cleavage in brain. N Engl J Med. 1975 Jun 12; 292(24):1269-73.
  347. Paxson CL, Lock J. Letter: Idiopathic hypoproteinemia in twins. JAMA. 1974 Dec 2; 230(9):1257-8.
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