Medical School

  • Medical Faculty, Friedrich Alexander University , 2005 , Erlangen , Germany


  • St. Louis Children's Hosital , 2007 , St. Louis , MO


  • St. Louis Children's Hospital , 2009 , St. Louis , MO


Pediatric Endocrinology
  • Boston Children's Hosital , 2015 , Boston , MA


Dr. Lennerz completed medical school at Friedrich Alexander University in Germany in 2005. She did her pediatric residency at St. Louis Children’s Hospital from 2006-2009, followed by a fellowship in pediatric endocrinology at Boston Children’s Hospital from 2009-2011 and 2014-2015. Dr. Lennerz spent 3 years from 2011-2014 at Ulm University to obtain credentialing in pediatrics and pediatric endocrinology in Germany and acquire focused training in obesity. She has joined the endocrine division at Boston Children’s Hospital after finishing her fellowship in 2015.

Dr. Lennerz research focus is on understanding cerebral mechanisms that regulate food intake and energy homeostasis in obesity and type one diabetes. Past and recent projects focus on how these brain circuits can be modified by metabolic signaling in relation to food intake.


  • American Board of Pediatrics, General Pediatrics
  • American Board of Pediatrics, Pediatric Endocrinology


Publications powered by Harvard Catalyst Profiles

  1. Diets Varying in Carbohydrate Content Differentially Alter Brain Activity in Homeostatic and Reward Regions in Adults. J Nutr. 2021 Aug 07; 151(8):2465-2476. View abstract
  2. Serum IGF1 and linear growth in children with congenital leptin deficiency before and after leptin substitution. Int J Obes (Lond). 2021 Jul; 45(7):1448-1456. View abstract
  3. Carbohydrate restriction for diabetes: rediscovering centuries-old wisdom. J Clin Invest. 2021 01 04; 131(1). View abstract
  4. [Innovative medical care concepts for adolescents with severe obesity]. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2020 Jul; 63(7):831-838. View abstract
  5. Health related quality of life associated with extreme obesity in adolescents - results from the baseline evaluation of the YES-study. Health Qual Life Outcomes. 2020 Mar 05; 18(1):58. View abstract
  6. Methylphenidate in children with monogenic obesity due to LEPR or MC4R deficiency improves feeling of satiety and reduces BMI-SDS-A case series. Pediatr Obes. 2020 01; 15(1):e12577. View abstract
  7. Refinement of the critical genomic region for hypoglycaemia in the Chromosome 9p deletion syndrome. Wellcome Open Res. 2019; 4:149. View abstract
  8. Treatment of Hypothalamic Obesity with Dextroamphetamine: A Case Series. Obes Facts. 2019; 12(1):91-102. View abstract
  9. Do adolescents with extreme obesity differ according to previous treatment seeking behavior? The Youth with Extreme obesity Study (YES) cohort. Int J Obes (Lond). 2019 01; 43(1):103-115. View abstract
  10. Functional and Phenotypic Characteristics of Human Leptin Receptor Mutations. J Endocr Soc. 2019 Jan 01; 3(1):27-41. View abstract
  11. Authors' Response. Pediatrics. 2018 08; 142(2). View abstract
  12. Management of Type 1 Diabetes With a Very Low-Carbohydrate Diet. Pediatrics. 2018 06; 141(6). View abstract
  13. Early childhood BMI trajectories in monogenic obesity due to leptin, leptin receptor, and melanocortin 4 receptor deficiency. Int J Obes (Lond). 2018 09; 42(9):1602-1609. View abstract
  14. Food Addiction, High-Glycemic-Index Carbohydrates, and Obesity. Clin Chem. 2018 01; 64(1):64-71. View abstract
  15. A Structured, Manual-Based Low-Level Intervention vs. Treatment as Usual Evaluated in a Randomized Controlled Trial for Adolescents with Extreme Obesity - the STEREO Trial. Obes Facts. 2017; 10(4):341-352. View abstract
  16. [Case series: BMI long courses in patients with extreme juvenile obesity. Short- and long-term success of long-term inpatient treatment]. MMW Fortschr Med. 2016 08; 158 Suppl 5:1-7. View abstract
  17. Biologically inactive leptin and early-onset extreme obesity. N Engl J Med. 2015 Jan 01; 372(1):48-54. View abstract
  18. Effects of sodium benzoate, a widely used food preservative, on glucose homeostasis and metabolic profiles in humans. Mol Genet Metab. 2015 Jan; 114(1):73-9. View abstract
  19. Monogenic forms of childhood obesity due to mutations in the leptin gene. Mol Cell Pediatr. 2014 Dec; 1(1):3. View abstract
  20. Plasma insulin levels in childhood are related to maternal factors--results of the Ulm Birth Cohort Study. Pediatr Diabetes. 2014 Sep; 15(6):453-63. View abstract
  21. Bariatric surgery in adolescents and young adults--safety and effectiveness in a cohort of 345 patients. Int J Obes (Lond). 2014 Mar; 38(3):334-40. View abstract
  22. Effects of dietary glycemic index on brain regions related to reward and craving in men. Am J Clin Nutr. 2013 Sep; 98(3):641-7. View abstract
  23. A case of phace syndrome and acquired hypopituitarism? Int J Pediatr Endocrinol. 2012 Jun 30; 2012(1):20. View abstract
  24. Brain activation during input from mechanoinsensitive versus polymodal C-nociceptors. J Neurosci. 2006 May 17; 26(20):5492-9. View abstract