MEDICAL SERVICES

EDUCATION

Medical School

  • University of Heidelberg , 1985 , Heidelberg , Germany

Internship

  • Children’s Hospital of University of Heidelberg , Heidelberg , Germany

Residency

Pediatrics
  • Boston Children's Hospital , 1993 , Boston , MA

Fellowship

Pediatric Infectious Diseases
  • Boston Children's Hospital , 1998 , Boston , MA

CERTIFICATIONS

  • American Board of Pediatrics, General Pediatrics
  • American Board of Pediatrics, Infectious Diseases

PUBLICATIONS

Publications powered by Harvard Catalyst Profiles

  1. Phosphate in Virulence of Candida albicans and Candida glabrata. J Fungi (Basel). 2020 Mar 26; 6(2). View abstract
  2. Phosphoric Metabolites Link Phosphate Import and Polysaccharide Biosynthesis for Candida albicans Cell Wall Maintenance. mBio. 2020 03 17; 11(2). View abstract
  3. Medical Deferred Action - Living on Borrowed Time. N Engl J Med. 2019 Oct 24; 381(17):1601-1603. View abstract
  4. Global Transcriptomic Analysis of the Candida albicans Response to Treatment with a Novel Inhibitor of Filamentation. mSphere. 2019 09 11; 4(5). View abstract
  5. Candida albicans Dispersed Cells Are Developmentally Distinct from Biofilm and Planktonic Cells. mBio. 2018 08 21; 9(4). View abstract
  6. Intersection of phosphate transport, oxidative stress and TOR signalling in Candida albicans virulence. PLoS Pathog. 2018 07; 14(7):e1007076. View abstract
  7. The Human Gut Microbial Metabolome Modulates Fungal Growth via the TOR Signaling Pathway. mSphere. 2017 Nov-Dec; 2(6). View abstract
  8. The Candida albicans TOR-Activating GTPases Gtr1 and Rhb1 Coregulate Starvation Responses and Biofilm Formation. mSphere. 2017 Nov-Dec; 2(6). View abstract
  9. Skin infections are eliminated by cooperation of the fibrinolytic and innate immune systems. Sci Immunol. 2017 Sep 22; 2(15). View abstract
  10. Fungi that Infect Humans. Microbiol Spectr. 2017 06; 5(3). View abstract
  11. Phosphate is the third nutrient monitored by TOR in Candida albicans and provides a target for fungal-specific indirect TOR inhibition. Proc Natl Acad Sci U S A. 2017 06 13; 114(24):6346-6351. View abstract
  12. Beauvericin Potentiates Azole Activity via Inhibition of Multidrug Efflux, Blocks Candida albicans Morphogenesis, and Is Effluxed via Yor1 and Circuitry Controlled by Zcf29. Antimicrob Agents Chemother. 2016 12; 60(12):7468-7480. View abstract
  13. Antagonism of Fluconazole and a Proton Pump Inhibitor against Candida albicans. Antimicrob Agents Chemother. 2016 Feb; 60(2):1145-7. View abstract
  14. Ribosomal protein S6 phosphorylation is controlled by TOR and modulated by PKA in Candida albicans. Mol Microbiol. 2015 Oct; 98(2):384-402. View abstract
  15. The silent crisis: children hurt by current immigration enforcement policies. JAMA Pediatr. 2014 Feb; 168(2):103-4. View abstract
  16. Physiologic expression of the Candida albicans pescadillo homolog is required for virulence in a murine model of hematogenously disseminated candidiasis. Eukaryot Cell. 2012 Dec; 11(12):1552-6. View abstract
  17. Harnessing Hsp90 function as a powerful, broadly effective therapeutic strategy for fungal infectious disease. Proc Natl Acad Sci U S A. 2009 Feb 24; 106(8):2818-23. View abstract
  18. The Candida albicans pescadillo homolog is required for normal hypha-to-yeast morphogenesis and yeast proliferation. Proc Natl Acad Sci U S A. 2008 Dec 30; 105(52):20918-23. View abstract
  19. Mucosal damage and neutropenia are required for Candida albicans dissemination. PLoS Pathog. 2008 Feb 08; 4(2):e35. View abstract
  20. CaNAT1, a heterologous dominant selectable marker for transformation of Candida albicans and other pathogenic Candida species. Infect Immun. 2005 Feb; 73(2):1239-42. View abstract
  21. Mos10 (Vps60) is required for normal filament maturation in Saccharomyces cerevisiae. Mol Microbiol. 2003 Sep; 49(5):1267-85. View abstract
  22. Nonfilamentous C. albicans mutants are avirulent. Cell. 1997 Sep 05; 90(5):939-49. View abstract
  23. Candida albicans strains heterozygous and homozygous for mutations in mitogen-activated protein kinase signaling components have defects in hyphal development. Proc Natl Acad Sci U S A. 1996 Nov 12; 93(23):13223-8. View abstract