EDUCATION

Graduate Degree

PhD, Psychology
  • Boston University School of Medicine , 1990 , Boston , MA

Medical School

  • Boston University School of Medicine , 1990 , Boston , MA

Internship

Pediatrics
  • Boston Children's Hospital , 1991 , Boston , MA

Residency

Pediatrics/Anesthesia
  • Boston Combined Residency Program (BCRP) , 1995 , Boston , MA

Fellowship

Pediatric Critical Care
  • Boston Children's Hospital , 1997 , Boston , MA

CERTIFICATIONS

  • American Board of Pediatrics, Critical Care Medicine

PUBLICATIONS

Publications powered by Harvard Catalyst Profiles

  1. Enhancement of the Mechanical and Drug-Releasing Properties of Poloxamer 407 Hydrogels with Casein. Pharm Res. 2021 Mar; 38(3):515-522. View abstract
  2. Initial Method for Characterization of Tympanic Membrane Drug Permeability in Human Temporal Bones In Situ. Front Neurol. 2021; 12:580392. View abstract
  3. Keeping Nanomedicine on Target. Nano Lett. 2021 01 13; 21(1):3-5. View abstract
  4. Local anesthesia enhanced with increasing high-frequency ultrasound intensity. Drug Deliv Transl Res. 2020 10; 10(5):1507-1516. View abstract
  5. Steroid-eluting contact lenses for corneal and intraocular inflammation. Acta Biomater. 2020 10 15; 116:149-161. View abstract
  6. Dually Enzyme- and Acid-Triggered Self-Immolative Ketal Glycoside Nanoparticles for Effective Cancer Prodrug Monotherapy. Nano Lett. 2020 07 08; 20(7):5465-5472. View abstract
  7. Light-triggered release of conventional local anesthetics from a macromolecular prodrug for on-demand local anesthesia. Nat Commun. 2020 05 08; 11(1):2323. View abstract
  8. Functionalized Multiarmed Polycaprolactones as Biocompatible Tissue Adhesives. ACS Appl Mater Interfaces. 2020 Apr 15; 12(15):17314-17320. View abstract
  9. Synthesis of Poly(acyclic orthoester)s: Acid-Sensitive Biomaterials for Enhancing Immune Responses of Protein Vaccine. Angew Chem Int Ed Engl. 2020 04 27; 59(18):7235-7239. View abstract
  10. The Duration of Nerve Block from Local Anesthetic Formulations in Male and Female Rats. Pharm Res. 2019 Nov 08; 36(12):179. View abstract
  11. Transcytosis of Nanomedicine for Tumor Penetration. . 2019 11 13; 19(11):8010-8020. View abstract
  12. Prolonged Duration Topical Corneal Anesthesia With the Cationic Lidocaine Derivative QX-314. Transl Vis Sci Technol. 2019 Sep; 8(5):28. View abstract
  13. Prolonged Duration Local Anesthesia by Combined Delivery of Capsaicin- and Tetrodotoxin-Loaded Liposomes. Anesth Analg. 2019 09; 129(3):709-717. View abstract
  14. Nanoscale systems for local drug delivery. Nano Today. 2019 Oct; 28. View abstract
  15. A Simple, Yet Multifunctional, Nanoformulation for Eradicating Tumors and Preventing Recurrence with Safely Low Administration Dose. . 2019 08 14; 19(8):5515-5523. View abstract
  16. Topical sustained drug delivery to the retina with a drug-eluting contact lens. Biomaterials. 2019 10; 217:119285. View abstract
  17. Polymer-tetrodotoxin conjugates to induce prolonged duration local anesthesia with minimal toxicity. Nat Commun. 2019 06 12; 10(1):2566. View abstract
  18. Reprogramming the microenvironment with tumor-selective angiotensin blockers enhances cancer immunotherapy. Proc Natl Acad Sci U S A. 2019 05 28; 116(22):10674-10680. View abstract
  19. Quantile Regression and Its Applications: A Primer for Anesthesiologists. Anesth Analg. 2019 04; 128(4):820-830. View abstract
  20. Prolonged Duration Local Anesthesia by Combined Delivery of Capsaicin- and Tetrodotoxin-Loaded Liposomes. Anesth Analg. 2019 Mar 11. View abstract
  21. Transtympanic Delivery of Local Anesthetics for Pain in Acute Otitis Media. Mol Pharm. 2019 04 01; 16(4):1555-1562. View abstract
  22. Intravenous treatment of choroidal neovascularization by photo-targeted nanoparticles. Nat Commun. 2019 02 18; 10(1):804. View abstract
  23. Nanoscale Bupivacaine Formulations To Enhance the Duration and Safety of Intravenous Regional Anesthesia. ACS Nano. 2019 01 22; 13(1):18-25. View abstract
  24. PLGA-encapsulation of the Pseudomonas aeruginosa PopB vaccine antigen improves Th17 responses and confers protection against experimental acute pneumonia. Vaccine. 2018 11 12; 36(46):6926-6932. View abstract
  25. Treatment of Streptococcus pneumoniae otitis media in a chinchilla model by transtympanic delivery of antibiotics. JCI Insight. 2018 10 04; 3(19). View abstract
  26. Externally triggered patient-controlled local anesthesia. Pain Manag. 2018 09 01; 8(5):313-315. View abstract
  27. Long-acting liposomal corneal anesthetics. Biomaterials. 2018 10; 181:372-377. View abstract
  28. Predicting the tissue depth for remote triggering of drug delivery systems. J Control Release. 2018 09 28; 286:55-63. View abstract
  29. Antibody-modified conduits for highly selective cytokine elimination from blood. JCI Insight. 2018 07 12; 3(13). View abstract
  30. Synergy between chemical permeation enhancers and drug permeation across the tympanic membrane. J Control Release. 2018 11 10; 289:94-101. View abstract
  31. Prolonged Duration Local Anesthesia Using Liposomal Bupivacaine Combined With Liposomal Dexamethasone and Dexmedetomidine. Anesth Analg. 2018 04; 126(4):1170-1175. View abstract
  32. BaTiO3-core Au-shell nanoparticles for photothermal therapy and bimodal imaging. Acta Biomater. 2018 05; 72:287-294. View abstract
  33. High-frequency, low-intensity ultrasound and microbubbles enhance nerve blockade. J Control Release. 2018 04 28; 276:150-156. View abstract
  34. Ultrasound-triggered liposomes for on-demand local anesthesia. Ther Deliv. 2018 01; 9(1):5-8. View abstract
  35. Hollow Silica Nanoparticles Penetrate the Peripheral Nerve and Enhance the Nerve Blockade from Tetrodotoxin. . 2018 01 10; 18(1):32-37. View abstract
  36. Light-Emitting Photon-Upconversion Nanoparticles in the Generation of Transdermal Reactive-Oxygen Species. ACS Appl Mater Interfaces. 2017 Dec 06; 9(48):41737-41747. View abstract
  37. Enhanced Triggering of Local Anesthetic Particles by Photosensitization and Photothermal Effect Using a Common Wavelength. . 2017 11 08; 17(11):7138-7145. View abstract
  38. Ultrasound-triggered local anaesthesia. Nat Biomed Eng. 2017; 1:644-653. View abstract
  39. Getting Drugs Across Biological Barriers. . 2017 Oct; 29(37). View abstract
  40. Tetrodotoxin, Epinephrine, and Chemical Permeation Enhancer Combinations in Peripheral Nerve Blockade. Anesth Analg. 2017 06; 124(6):1804-1812. View abstract
  41. Combination Clearance Therapy and Barbiturate Coma for Severe Carbamazepine Overdose. Pediatrics. 2017 May; 139(5). View abstract
  42. Strong tissue glue with tunable elasticity. Acta Biomater. 2017 04 15; 53:93-99. View abstract
  43. Multiply repeatable and adjustable on-demand phototriggered local anesthesia. J Control Release. 2017 04 10; 251:68-74. View abstract
  44. Ultrasensitive Phototriggered Local Anesthesia. . 2017 02 08; 17(2):660-665. View abstract
  45. Drug delivery systems for prolonged duration local anesthesia. Mater Today (Kidlington). 2017 Jan-Feb; 20(1):22-31. View abstract
  46. 1074: SEVERITY OF HEMODYNAMIC INSTABILITY AROUND HIGH-DOSE VASOACTIVE SYRINGE CHANGES IN THE PICU. Crit Care Med. 2016 Dec; 44(12 Suppl 1):344. View abstract
  47. Incorporation of heparin-binding proteins into preformed dextran sulfate-chitosan nanoparticles. Int J Nanomedicine. 2016; 11:6149-6159. View abstract
  48. Phototriggered Drug Delivery Using Inorganic Nanomaterials. Bioconjug Chem. 2017 01 18; 28(1):98-104. View abstract
  49. Core-Shell Nanostars for Multimodal Therapy and Imaging. Theranostics. 2016; 6(13):2306-2313. View abstract
  50. Treatment of otitis media by transtympanic delivery of antibiotics. Sci Transl Med. 2016 09 14; 8(356):356ra120. View abstract
  51. Latanoprost-Eluting Contact Lenses in Glaucomatous Monkeys. Ophthalmology. 2016 10; 123(10):2085-92. View abstract
  52. Drug delivery, biomaterials and nanomedicine: an interview with Daniel S Kohane. Future Sci OA. 2016 Sep; 2(3):FSO138. View abstract
  53. Enhanced Precision of Nanoparticle Phototargeting in Vivo at a Safe Irradiance. . 2016 07 13; 16(7):4516-20. View abstract
  54. RNA therapeutics - The potential treatment for myocardial infarction. Regen Ther. 2016 Jun; 4:83-91. View abstract
  55. A Supramolecular Shear-Thinning Anti-Inflammatory Steroid Hydrogel. . 2016 Aug; 28(31):6680-6. View abstract
  56. Extended Release of Native Drug Conjugated in Polyketal Microparticles. J Am Chem Soc. 2016 05 18; 138(19):6127-30. View abstract
  57. Titanium Coating of the Boston Keratoprosthesis. Transl Vis Sci Technol. 2016 Apr; 5(2):17. View abstract
  58. Self-assembled gemcitabine-gadolinium nanoparticles for magnetic resonance imaging and cancer therapy. Acta Biomater. 2016 Mar; 33:34-9. View abstract
  59. Phototriggered Local Anesthesia. . 2016 Jan 13; 16(1):177-81. View abstract
  60. Repeatable and adjustable on-demand sciatic nerve block with phototriggerable liposomes. Proc Natl Acad Sci U S A. 2015 Dec 22; 112(51):15719-24. View abstract
  61. Selective binding of C-6 OH sulfated hyaluronic acid to the angiogenic isoform of VEGF(165). Biomaterials. 2016 Jan; 77:130-138. View abstract
  62. New Strategies in Cancer Nanomedicine. Annu Rev Pharmacol Toxicol. 2016; 56:41-57. View abstract
  63. Ultraviolet light-mediated drug delivery: Principles, applications, and challenges. J Control Release. 2015 Dec 10; 219:31-42. View abstract
  64. Photoresponsive nanoparticles for drug delivery. Nano Today. 2015 Aug 01; 10(4):451-467. View abstract
  65. Efficient Triplet-Triplet Annihilation-Based Upconversion for Nanoparticle Phototargeting. . 2015 Oct 14; 15(10):6332-8. View abstract
  66. Nonlinear Optics: NIR-Triggered Drug Delivery by Collagen-Mediated Second Harmonic Generation (Adv. Healthcare Mater. 8/2015). Adv Healthc Mater. 2015 Jun; 4(8):1108. View abstract
  67. Corneal Anesthesia With Site 1 Sodium Channel Blockers and Dexmedetomidine. Invest Ophthalmol Vis Sci. 2015 Jun; 56(6):3820-6. View abstract
  68. NIR-triggered drug delivery by collagen-mediated second harmonic generation. Adv Healthc Mater. 2015 Jun 03; 4(8):1159-63. View abstract
  69. Preparation and characterization of SDF-1a-chitosan-dextran sulfate nanoparticles. J Vis Exp. 2015 Jan 22; (95):52323. View abstract
  70. Aptamer photoregulation in vivo. Proc Natl Acad Sci U S A. 2014 Dec 02; 111(48):17099-103. View abstract
  71. Clinicians' perspectives on the use of drug-eluting contact lenses for the treatment of glaucoma. Ther Deliv. 2014 Oct; 5(10):1077-83. View abstract
  72. A two-component pre-seeded dermal-epidermal scaffold. Acta Biomater. 2014 Dec; 10(12):4928-4938. View abstract
  73. Prospects for near-infrared technology in remotely triggered drug delivery. Expert Opin Drug Deliv. 2014 Nov; 11(11):1681-5. View abstract
  74. Photothermally targeted thermosensitive polymer-masked nanoparticles. . 2014 Jul 09; 14(7):3697-701. View abstract
  75. Prevention of ventilator-induced lung edema by inhalation of nanoparticles releasing ruthenium red. Am J Respir Cell Mol Biol. 2014 Jun; 50(6):1107-17. View abstract
  76. Interview with Daniel Kohane. Ther Deliv. 2014 Apr; 5(4):387-9. View abstract
  77. Multivesicular liposomal bupivacaine at the sciatic nerve. Biomaterials. 2014 May; 35(15):4557-64. View abstract
  78. Near-infrared-actuated devices for remotely controlled drug delivery. Proc Natl Acad Sci U S A. 2014 Jan 28; 111(4):1349-54. View abstract
  79. Prevention of peritoneal adhesions using polymeric rheological blends. Acta Biomater. 2014 Mar; 10(3):1187-93. View abstract
  80. Photoswitchable nanoparticles for in vivo cancer chemotherapy. Proc Natl Acad Sci U S A. 2013 Nov 19; 110(47):19048-53. View abstract
  81. Photoactive electrospun fibers for inducing cell death. Adv Healthc Mater. 2014 Apr; 3(4):494-9. View abstract
  82. SDF-1a in glycan nanoparticles exhibits full activity and reduces pulmonary hypertension in rats. Biomacromolecules. 2013 Nov 11; 14(11):4009-20. View abstract
  83. In vivo performance of a drug-eluting contact lens to treat glaucoma for a month. Biomaterials. 2014 Jan; 35(1):432-9. View abstract
  84. A photo-triggered layered surface coating producing reactive oxygen species. Biomaterials. 2013 Dec; 34(38):9763-9. View abstract
  85. Biodegradable mesostructured polymer membranes. . 2013 Sep 11; 13(9):4410-5. View abstract
  86. Enhanced photothermal effect of plasmonic nanoparticles coated with reduced graphene oxide. . 2013 Sep 11; 13(9):4075-9. View abstract
  87. Long-lasting antifouling coating from multi-armed polymer. Langmuir. 2013 Aug 13; 29(32):10087-94. View abstract
  88. Topical drug formulations for prolonged corneal anesthesia. Cornea. 2013 Jul; 32(7):1040-5. View abstract
  89. Microdevices for nanomedicine. Mol Pharm. 2013 Jun 03; 10(6):2127-44. View abstract
  90. A Stiff Injectable Biodegradable Elastomer. Adv Funct Mater. 2013 Mar 25; 23(12):1527-1533. View abstract
  91. Local toxicity from local anesthetic polymeric microparticles. Anesth Analg. 2013 Apr; 116(4):794-803. View abstract
  92. Controlled-release systems in neuropathic pain. Pain Manag. 2013 Mar; 3(2):91-3. View abstract
  93. Synthetic ligand-coated magnetic nanoparticles for microfluidic bacterial separation from blood. . 2014 Jan 08; 14(1):1-5. View abstract
  94. Synthesis and proton NMR spectroscopy of intra-vesicular gamma-aminobutyric acid (GABA). Annu Int Conf IEEE Eng Med Biol Soc. 2013; 2013:1093-5. View abstract
  95. Modular 'click-in-emulsion' bone-targeted nanogels. . 2013 Mar 13; 25(10):1449-54. View abstract
  96. Benchtop fabrication of microfluidic systems based on curable polymers with improved solvent compatibility. Lab Chip. 2013 Jan 21; 13(2):252-9. View abstract
  97. Formulations for trans-tympanic antibiotic delivery. Biomaterials. 2013 Jan; 34(4):1281-8. View abstract
  98. Materials to clinical devices: technologies for remotely triggered drug delivery. Clin Ther. 2012 Nov; 34(11):S25-35. View abstract
  99. Prolonged nerve blockade delays the onset of neuropathic pain. Proc Natl Acad Sci U S A. 2012 Oct 23; 109(43):17555-60. View abstract
  100. Nanocomposite gold-silk nanofibers. . 2012 Oct 10; 12(10):5403-6. View abstract
  101. Duration and local toxicity of sciatic nerve blockade with coinjected site 1 sodium-channel blockers and quaternary lidocaine derivatives. Reg Anesth Pain Med. 2012 Sep-Oct; 37(5):483-9. View abstract
  102. Macroporous nanowire nanoelectronic scaffolds for synthetic tissues. Nat Mater. 2012 Nov; 11(11):986-94. View abstract
  103. Shedding light on nanomedicine. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2012 Nov-Dec; 4(6):638-62. View abstract
  104. The smartest materials: the future of nanoelectronics in medicine. ACS Nano. 2012 Aug 28; 6(8):6541-5. View abstract
  105. Thermoresponsive nanogels for prolonged duration local anesthesia. Acta Biomater. 2012 Oct; 8(10):3596-605. View abstract
  106. Electrospun drug-eluting sutures for local anesthesia. J Control Release. 2012 Aug 10; 161(3):903-9. View abstract
  107. Delivering bioactive molecules as instructive cues to engineered tissues. Expert Opin Drug Deliv. 2012 Apr; 9(4):473-92. View abstract
  108. Photoswitchable nanoparticles for triggered tissue penetration and drug delivery. J Am Chem Soc. 2012 May 30; 134(21):8848-55. View abstract
  109. Injectable scaffolds achieve sustained siRNA release for tissue repair. Nanomedicine (Lond). 2012 Mar; 7(3):315-6. View abstract
  110. External electric fields trigger drug release from new hydrogel formulation. Nanomedicine (Lond). 2012 Mar; 7(3):316. View abstract
  111. Novel resonating nanowire arrays function as highly sensitive biosensors. Nanomedicine (Lond). 2012 Mar; 7(3):315. View abstract
  112. Toxicogenomic analysis of a sustained release local anesthetic delivery system. Biomaterials. 2012 May; 33(13):3586-93. View abstract
  113. An in situ cross-linking hybrid hydrogel for controlled release of proteins. Acta Biomater. 2012 May; 8(5):1703-9. View abstract
  114. Nanogel scavengers for drugs: local anesthetic uptake by thermoresponsive nanogels. Acta Biomater. 2012 Apr; 8(4):1450-8. View abstract
  115. Nanowired three-dimensional cardiac patches. Nat Nanotechnol. 2011 Sep 25; 6(11):720-5. View abstract
  116. Hydroxyapatite for keratoprosthesis biointegration. Invest Ophthalmol Vis Sci. 2011 Sep 22; 52(10):7392-9. View abstract
  117. Nanoparticles targeting the infarcted heart. . 2011 Oct 12; 11(10):4411-4. View abstract
  118. Liposomes for HIV prophylaxis. Biomaterials. 2011 Nov; 32(33):8663-8. View abstract
  119. A prototype antifungal contact lens. Invest Ophthalmol Vis Sci. 2011 Aug 09; 52(9):6286-91. View abstract
  120. Microgels for efficient protein purification. . 2011 Sep 22; 23(36):H258-62. View abstract
  121. Surface modification and drug delivery for biointegration. Ther Deliv. 2011 Jun; 2(6):737-52. View abstract
  122. Elasticity and safety of alkoxyethyl cyanoacrylate tissue adhesives. Acta Biomater. 2011 Aug; 7(8):3150-7. View abstract
  123. Nanotechnology for surgeons. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2011 May-Jun; 3(3):223-8. View abstract
  124. Magnetically triggered nanocomposite membranes: a versatile platform for triggered drug release. . 2011 Mar 09; 11(3):1395-400. View abstract
  125. Drug delivery and translation. Drug Deliv Transl Res. 2011 Feb; 1(1):4-6. View abstract
  126. Nanotechnological strategies for engineering complex tissues. Nat Nanotechnol. 2011 Jan; 6(1):13-22. View abstract
  127. Remotely triggerable drug delivery systems. . 2010 Nov 24; 22(44):4925-43. View abstract
  128. Combinatorial extracellular matrices for human embryonic stem cell differentiation in 3D. Biomacromolecules. 2010 Aug 09; 11(8):1909-14. View abstract
  129. A microcomposite hydrogel for repeated on-demand ultrasound-triggered drug delivery. Biomaterials. 2010 Jul; 31(19):5208-17. View abstract
  130. Prolonged sensory-selective nerve blockade. Proc Natl Acad Sci U S A. 2010 Feb 23; 107(8):3740-5. View abstract
  131. Rheological blends for drug delivery. II. Prolongation of nerve blockade, biocompatibility, and in vitro-in vivo correlations. J Biomed Mater Res A. 2010 Feb; 92(2):586-95. View abstract
  132. Rheological blends for drug delivery. I. Characterization in vitro. J Biomed Mater Res A. 2010 Feb; 92(2):575-85. View abstract
  133. Photo-targeted nanoparticles. . 2010 Jan; 10(1):250-4. View abstract
  134. Injectable in situ cross-linking hydrogels for local antifungal therapy. Biomaterials. 2010 Feb; 31(6):1444-52. View abstract
  135. Three-dimensional conductive constructs for nerve regeneration. J Biomed Mater Res A. 2009 Nov; 91(2):519-27. View abstract
  136. A magnetically triggered composite membrane for on-demand drug delivery. . 2009 Oct; 9(10):3651-7. View abstract
  137. Preparation of monodisperse biodegradable polymer microparticles using a microfluidic flow-focusing device for controlled drug delivery. Small. 2009 Jul; 5(13):1575-81. View abstract
  138. Contact lenses for drug delivery. Semin Ophthalmol. 2009 May-Jun; 24(3):156-60. View abstract
  139. Prolonged duration local anesthesia with minimal toxicity. Proc Natl Acad Sci U S A. 2009 Apr 28; 106(17):7125-30. View abstract
  140. A drug-eluting contact lens. Invest Ophthalmol Vis Sci. 2009 Jul; 50(7):3346-52. View abstract
  141. Effect of chemical permeation enhancers on nerve blockade. Mol Pharm. 2009 Jan-Feb; 6(1):265-73. View abstract
  142. Intracellular drug delivery by poly(lactic-co-glycolic acid) nanoparticles, revisited. Mol Pharm. 2009 Jan-Feb; 6(1):190-201. View abstract
  143. Spray-dried lipid-hyaluronan-polymethacrylate microparticles for drug delivery in the peritoneum. J Biomed Mater Res A. 2008 Dec 01; 87(3):825-31. View abstract
  144. The biocompatibility of mesoporous silicates. Biomaterials. 2008 Oct; 29(30):4045-55. View abstract
  145. Microparticles for inhalational delivery of antipseudomonal antibiotics. AAPS J. 2008 Jun; 10(2):254-60. View abstract
  146. Local myotoxicity from sustained release of bupivacaine from microparticles. Anesthesiology. 2008 May; 108(5):921-8. View abstract
  147. Polymeric biomaterials in tissue engineering. Pediatr Res. 2008 May; 63(5):487-91. View abstract
  148. Inhaled agonists of soluble guanylate cyclase induce selective pulmonary vasodilation. Am J Respir Crit Care Med. 2007 Dec 01; 176(11):1138-45. View abstract
  149. Antifungal hydrogels. Proc Natl Acad Sci U S A. 2007 Aug 07; 104(32):12994-8. View abstract
  150. Polymers in the prevention of peritoneal adhesions. Eur J Pharm Biopharm. 2008 Jan; 68(1):57-66. View abstract
  151. Prevention of peritoneal adhesions with an in situ cross-linkable hyaluronan hydrogel delivering budesonide. J Control Release. 2007 Jul 31; 120(3):178-85. View abstract
  152. Peritoneal adhesion prevention with an in situ cross-linkable hyaluronan gel containing tissue-type plasminogen activator in a rabbit repeated-injury model. Biomaterials. 2007 Sep; 28(25):3704-13. View abstract
  153. In situ cross-linkable hyaluronan hydrogels containing polymeric nanoparticles for preventing postsurgical adhesions. Ann Surg. 2007 May; 245(5):819-24. View abstract
  154. Photocrosslinkable hydrogel for myocyte cell culture and injection. . 2007 May; 81(2):312-22. View abstract
  155. Dextran-based in situ cross-linked injectable hydrogels to prevent peritoneal adhesions. Biomaterials. 2007 Aug; 28(23):3418-26. View abstract
  156. Microparticles and nanoparticles for drug delivery. Biotechnol Bioeng. 2007 Feb 01; 96(2):203-9. View abstract
  157. Anti-inflammatory function of an in situ cross-linkable conjugate hydrogel of hyaluronic acid and dexamethasone. Biomaterials. 2007 Apr; 28(10):1778-86. View abstract
  158. Tetrodotoxin for prolonged local anesthesia with minimal myotoxicity. Muscle Nerve. 2006 Dec; 34(6):747-53. View abstract
  159. Hyaluronic acid-based microgels and microgel networks for vocal fold regeneration. Biomacromolecules. 2006 Dec; 7(12):3336-44. View abstract
  160. The prevention of peritoneal adhesions by in situ cross-linking hydrogels of hyaluronic acid and cellulose derivatives. Biomaterials. 2007 Feb; 28(6):975-83. View abstract
  161. Peritoneal application of chitosan and UV-cross-linkable chitosan. J Biomed Mater Res A. 2006 Sep 15; 78(4):668-75. View abstract
  162. Micromolding of photocrosslinkable chitosan hydrogel for spheroid microarray and co-cultures. Biomaterials. 2006 Oct; 27(30):5259-67. View abstract
  163. In situ cross-linkable hyaluronic acid hydrogels prevent post-operative abdominal adhesions in a rabbit model. Biomaterials. 2006 Sep; 27(27):4698-705. View abstract
  164. A photolithographic method to create cellular micropatterns. Biomaterials. 2006 Sep; 27(27):4755-64. View abstract
  165. Biodegradable polymeric microspheres and nanospheres for drug delivery in the peritoneum. J Biomed Mater Res A. 2006 May; 77(2):351-61. View abstract
  166. Tissue injury from tricyclic antidepressants used as local anesthetics. Anesth Analg. 2005 Dec; 101(6):1838-43. View abstract
  167. Prolonged duration local anesthesia with lipid-protein-sugar particles containing bupivacaine and dexamethasone. J Biomed Mater Res A. 2005 Nov 01; 75(2):458-64. View abstract
  168. Complex coacervates for thermally sensitive controlled release of flavor compounds. J Agric Food Chem. 2005 Sep 21; 53(19):7518-25. View abstract
  169. Engineering vascularized skeletal muscle tissue. Nat Biotechnol. 2005 Jul; 23(7):879-84. View abstract
  170. Case records of the Massachusetts General Hospital. Case 16-2005. A nine-year-old girl with headaches and hypertension. N Engl J Med. 2005 May 26; 352(21):2223-31. View abstract
  171. In vivo evaluation of tetrahedral amorphous carbon. Biomaterials. 2005 Feb; 26(5):465-73. View abstract
  172. Injectable microparticle-gel system for prolonged and localized lidocaine release. I. In vitro characterization. J Biomed Mater Res A. 2004 Sep 01; 70(3):412-9. View abstract
  173. Injectable microparticle-gel system for prolonged and localized lidocaine release. II. In vivo anesthetic effects. J Biomed Mater Res A. 2004 Sep 01; 70(3):459-66. View abstract
  174. pH-triggered microparticles for peptide vaccination. J Immunol. 2004 Aug 15; 173(4):2578-85. View abstract
  175. Prolongation of sciatic nerve blockade by in situ cross-linked hyaluronic acid. Biomaterials. 2004 Aug; 25(19):4797-804. View abstract
  176. Site 1 sodium channel blockers prolong the duration of sciatic nerve blockade from tricyclic antidepressants. Pain. 2004 Jul; 110(1-2):432-8. View abstract
  177. Microparticulate formulations for the controlled release of interleukin-2. J Pharm Sci. 2004 May; 93(5):1100-9. View abstract
  178. Effect of excipient composition on the biocompatibility of bupivacaine-containing microparticles at the sciatic nerve. J Biomed Mater Res A. 2004 Mar 15; 68(4):651-9. View abstract
  179. pH-triggered release of macromolecules from spray-dried polymethacrylate microparticles. Pharm Res. 2003 Oct; 20(10):1533-8. View abstract
  180. Local anesthetics inhibit uterine activity in vitro. Possible application on preterm labor prevention and treatment. Fetal Diagn Ther. 2003 Sep-Oct; 18(5):292-6. View abstract
  181. Prolonged duration local anesthesia from tetrodotoxin-enhanced local anesthetic microspheres. Pain. 2003 Jul; 104(1-2):415-21. View abstract
  182. Effectiveness of muscimol-containing microparticles against pilocarpine-induced focal seizures. Epilepsia. 2002 Dec; 43(12):1462-8. View abstract
  183. Lipid-sugar particles for intracranial drug delivery: safety and biocompatibility. Brain Res. 2002 Aug 16; 946(2):206-13. View abstract
  184. Biocompatibility of lipid-protein-sugar particles containing bupivacaine in the epineurium. J Biomed Mater Res. 2002 Mar 05; 59(3):450-9. View abstract
  185. BID mediates neuronal cell death after oxygen/ glucose deprivation and focal cerebral ischemia. Proc Natl Acad Sci U S A. 2001 Dec 18; 98(26):15318-23. View abstract
  186. High concentrations of adrenergic antagonists prolong sciatic nerve blockade by tetrodotoxin. Acta Anaesthesiol Scand. 2001 Aug; 45(7):899-905. View abstract
  187. Effects of adrenergic agonists and antagonists on tetrodotoxin-induced nerve block. Reg Anesth Pain Med. 2001 May-Jun; 26(3):239-45. View abstract
  188. Sciatic nerve blockade with lipid-protein-sugar particles containing bupivacaine. Pharm Res. 2000 Oct; 17(10):1243-9. View abstract
  189. The local anesthetic properties and toxicity of saxitonin homologues for rat sciatic nerve block in vivo. Reg Anesth Pain Med. 2000 Jan-Feb; 25(1):52-9. View abstract
  190. Vanilloid receptor agonists potentiate the in vivo local anesthetic activity of percutaneously injected site 1 sodium channel blockers. Anesthesiology. 1999 Feb; 90(2):524-34. View abstract
  191. Sciatic nerve blockade in infant, adolescent, and adult rats: a comparison of ropivacaine with bupivacaine. Anesthesiology. 1998 Nov; 89(5):1199-208; discussion 10A. View abstract
  192. A re-examination of tetrodotoxin for prolonged duration local anesthesia. Anesthesiology. 1998 Jul; 89(1):119-31. View abstract
  193. Stress-induced proteins in aortic smooth muscle cells and aorta of hypertensive rats. Am J Physiol. 1990 Jun; 258(6 Pt 2):H1699-705. View abstract