MEDICAL SERVICES
Departments
Programs
Languages
-
English
EDUCATION
Medical School
- Colombian School of Medicine , 1991 , Bogota , Colombia
Internship
Surgical
- Boston University , 1997 , Boston , MA
Residency
Anesthesia
- Brigham and Women's Hospital , 2000 , Boston , MA
Fellowship
Pediatric Anesthesia and Critical Care
- Boston Children's Hospital , 2001 , Boston , MA
Fellowship
Research
- Boston Children's Hospital , 2002 , Boston , MA
CERTIFICATIONS
- American Board of Anesthesiology
PUBLICATIONS
Publications powered by Harvard Catalyst Profiles
- Coagulopathy and Thrombosis as a Result of Severe COVID-19 Infection: A Microvascular Focus. Thromb Haemost. 2020 Dec; 120(12):1668-1679. View abstract
- In silico features of ADAMTS13 contributing to plasmatic ADAMTS13 levels in neonates with congenital heart disease. Thromb Res. 2020 09; 193:66-76. View abstract
- TissueCoCoPUTs: Novel Human Tissue-Specific Codon and Codon-Pair Usage Tables Based on Differential Tissue Gene Expression. J Mol Biol. 2020 05 15; 432(11):3369-3378. View abstract
- Magnetic Resonance-Based Diagnostics for Bleeding Assessment in Neonatal Cardiac Surgery. Ann Thorac Surg. 2020 06; 109(6):1931-1936. View abstract
- Transition from Hemochron Response to Hemochron Signature Elite Activated Clotting Time Devices in a Congenital Cardiac Surgery Practice. J Extra Corpor Technol. 2019 Dec; 51(4):221-226. View abstract
- A Single Synonymous Variant (c.354G>A [p.P118P]) in ADAMTS13 Confers Enhanced Specific Activity. Int J Mol Sci. 2019 Nov 15; 20(22). View abstract
- Results of a phase 1 multicentre investigation of dexmedetomidine bolus and infusion in corrective infant cardiac surgery. Br J Anaesth. 2019 12; 123(6):839-852. View abstract
- Translational and transcriptional responses in human primary hepatocytes under hypoxia. Am J Physiol Gastrointest Liver Physiol. 2019 06 01; 316(6):G720-G734. View abstract
- von Willebrand factor/ADAMTS-13 interactions at birth: implications for thrombosis in the neonatal period. J Thromb Haemost. 2019 Mar; 17(3):429-440. View abstract
- Thromboelastography Is Associated With Surrogates for Bleeding After Pediatric Cardiac Operations. Ann Thorac Surg. 2018 09; 106(3):799-806. View abstract
- A red cell preservation strategy reduces postoperative transfusions in pediatric heart surgery patients. Paediatr Anaesth. 2018 05; 28(5):450-457. View abstract
- Preoperative Thromboelastographic Profile of Patients with Congenital Heart Disease: Association of Hypercoagulability and Decreased Heparin Response. J Cardiothorac Vasc Anesth. 2018 08; 32(4):1657-1663. View abstract
- Elevated preoperative von Willebrand factor is associated with perioperative thrombosis in infants and neonates with congenital heart disease. J Thromb Haemost. 2017 12; 15(12):2306-2316. View abstract
- Compounding variants rescue the effect of a deleterious ADAMTS13 mutation in a child with severe congenital heart disease. Thromb Res. 2017 10; 158:98-101. View abstract
- Relationship Between Transfusion of Blood Products and the Incidence of Thrombotic Complications in Neonates and Infants Undergoing Cardiac Surgery. J Cardiothorac Vasc Anesth. 2017 Dec; 31(6):1943-1948. View abstract
- Hypoxic preconditioning decreases nuclear factor ?B activity via Disrupted in Schizophrenia-1. Int J Biochem Cell Biol. 2016 Jan; 70:140-8. View abstract
- Effects of the fibroblast activation protein on the invasion and migration of gastric cancer. Exp Mol Pathol. 2013 Dec; 95(3):350-56. View abstract
- Effects of the fibroblast activation protein on the invasion and migration of gastric cancer. Exp Mol Pathol. 2013 Oct 25. View abstract
- ß-Ionone arrests cell cycle of gastric carcinoma cancer cells by a MAPK pathway. Arch Toxicol. 2013 Oct; 87(10):1797-808. View abstract
- Methods to assess tissue permeability. Methods Mol Biol. 2013; 1066:81-8. View abstract
- Apoptosis initiation of ß-ionone in SGC-7901 gastric carcinoma cancer cells via a PI3K-AKT pathway. Arch Toxicol. 2013 Mar; 87(3):481-90. View abstract
- Ketamine activates cell cycle signaling and apoptosis in the neonatal rat brain. Anesthesiology. 2010 May; 112(5):1155-63. View abstract
- Disrupted in Schizophrenia-1 (DISC1)Regulates ATM-mediated NFkappaB Activation during Hypoxia and Re-oxygenation. FASEB meeting. 2010. View abstract
- Dexmedetomidine is less pro-apoptotic than ketamine in the neonatal rat brain. ASA. 2009. View abstract
- Adenosine signaling mediates SUMO-1 modification of IkappaBalpha during hypoxia and reoxygenation. J Biol Chem. 2009 May 15; 284(20):13686-95. View abstract
- Adenosine signaling mediates small ubiquitin-like protein (sumo-1) modification of IKappaBalpha during hypoxia and re-oxygenation. In press, Journal of Biological Chemistry. 2009. View abstract
- Anesthesia for Pediatric Thoracic Surgery. Springer Science and Business Media ( Phillip Hartigan). 2009. View abstract
- Prolonged exposure to ketamine increases brain derived neurotrophic factor levels in developing rat brains. 2009; 4(1):11-16. View abstract
- Prolonged exposure to ketamine increases brain derived neurotrophic factor levels in developing rat brains. Curr Drug Saf. 2009 Jan; 4(1):11-6. View abstract
- Noxious Stimulation Attenuates Ketamine and Isoflurane-Induced Neuroapoptosis in the P7 Rat Brain. ASA, 2008. 2008. View abstract
- Ketamine Activates Cell Cycle Events and Apoptosis in the Neonatal Rat Brain. ASA, 2008. 2008. View abstract
- Pulmonary anti-inflammatory adaptation to hypoxia through adenosine-mediated Cullin-1 Deneddylation. ASA, San Francisco CA. 2007. View abstract
- Central Venous Access in the Neonate. 2007. View abstract
- Identification of ectonucleotidases CD39 and CD73 in innate protection during acute lung injury. J Immunol. 2007 Jun 15; 178(12):8127-37. View abstract
- Antiinflammatory adaptation to hypoxia through adenosine-mediated cullin-1 deneddylation. FASEB meeting, 2007. Washington DC. 2007. View abstract
- Identification of ecto-nucleotidases CD39 and CD73 in innate protection during acute lung injury. J Immunol, In press. 2007. View abstract
- Antiinflammatory adaptation to hypoxia through adenosine-mediated cullin-1 deneddylation. J Clin Invest. 2007 Mar; 117(3):703-11. View abstract
- Mechanical Ventilation of the Neonate. Cambridge Press. 2007. View abstract
- Early tracheal extubation after liver or multivisceral transplantation in infant and toddler recipients: Is it safe?. ASA. 2006. View abstract
- Transcriptional Repression of Na-K-2Cl-cotransporter NKCC1 by Hypoxia Inducible Factor-1. AJP. Cell Physiol. 2006; 291:C282-C289. View abstract
- Identification of Molecular Anti-inflammatory Mechanisms of Adenosine: Cullin-1 Denedddylation during Hypoxic Preconditioning. 8th International Symposium on Adenosine and Adenine Nucleotides. 2006. View abstract
- Endothelial catabolism of extracellular adenosine during hypoxia: the role of surface adenosine deaminase and CD26. Blood. 2006 Sep 01; 108(5):1602-10. View abstract
- Endothelial Catabolism of Extracellular Adenosine during Hypoxia: Role of Surface Adenosine Deaminase and CD26. Blood. Epub ahead of print. 2006. View abstract
- HIF-dependent Repression of Na-K-2Clcotransporter (NKCC1) in Hypoxia. FASEB meeting 2006. San Francisco CA. 2006. View abstract
- Transcriptional repression of Na-K-2Cl cotransporter NKCC1 by hypoxia-inducible factor-1. . 2006 Aug; 291(2):C282-9. View abstract
- Anesthetic Management of a Patient with Hepatopulmonary Syndrome, Prolonged QTc Interval and Panhypopituitarism for Liver Transplantation. Society of Pediatric Anesthesia meeting. 2006. View abstract
- Methods to assess tissue permeability. Methods Mol Biol. 2006; 341:111-7. View abstract
- Transcriptional Repression of Na-K-2Cl-cotransporter (NKCC1) by Hypoxia Inducible Factor 1. Keystone Symposia. 2005. View abstract
- Anesthesia for Emergent non-cardiac Surgery in neonates with Unpalliated Hypoplastic Left Heart Syndrome. SPA/AAP. 2005. View abstract
- Methods in Molecular Biology. Methods to Assess Tissue Permeability. Cell-Cell Interactions. 2005; 341:111-117. View abstract
- Crucial role for ecto-5'-nucleotidase (CD73) in vascular leakage during hypoxia. J Exp Med. 2004 Dec 06; 200(11):1395-405. View abstract
- Critical Role for ecto-5'nucleotidase in pulmonary vascular permeability during hypoxia. ASA. 2004. View abstract
- Endogenous adenosine produced during hypoxia attenuates neutrophil accumulation: coordination by extracellular nucleotide metabolism. Blood. 2004 Dec 15; 104(13):3986-92. View abstract
- The dynamic influences of hypoxia on extracellular nucleotide metabolism and nucleoside signalling. Purines 2004. 2004. View abstract
- Prolonged Ketamine Administration increases brain derived neurotrophic factor in developing rat brains. 2003. View abstract
- Coordinated adenine nucleotide phosphohydrolysis and nucleoside signaling in posthypoxic endothelium: role of ectonucleotidases and adenosine A2B receptors. J Exp Med. 2003 Sep 01; 198(5):783-96. View abstract
- Implications of hypoxia on mucosal barrier function. Cell Mol Biol (Noisy-le-grand). 2003 Feb; 49(1):77-87. View abstract
- Lung growth after reduced size transplantation in a sheep model. Transplantation. 1999 Jan 27; 67(2):233-40. View abstract
- Insulin-like growth factor-I gene expression in three models of accelerated lung growth. J Pediatr Surg. 1998 Jul; 33(7):1057-60; discussion 1061. View abstract
- The use of expandable metallic stents for acute tracheal stenosis in the growing lamb. J Pediatr Surg. 1998 Jul; 33(7):1038-41; discussion 1041-2. View abstract
- Lung growth following reduced-size lung transplantation in a sheep model. 1998. View abstract
- Pulmonary blood flow distribution during partial liquid ventilation. J Appl Physiol (1985). 1998 May; 84(5):1540-50. View abstract
- Insulin like growth factor I gene expression in three models of accelerated lung growth. 1997. View abstract
- The use of expandable metallic stents for acute tracheal stenosis in the growing lamb. 1997. View abstract
- Effects of nitric oxide on hyperinflation-induced pulmonary hypertension in the isolated-perfused lung. Crit Care Med. 1996 Aug; 24(8):1388-95. View abstract
- Continuos intrapulmonary distention with perfluorocarbon does not result in postnatal lung growth in adult sheep. 1996. View abstract
- Redistribution of pulmonary blood flow during partial liquid ventilation. 1996. View abstract
- University of Wisconsin cerebroplegia in a piglet survival model of circulatory arrest. Ann Thorac Surg. 1995 Dec; 60(6 Suppl):S494-500. View abstract
- The effect of nitric oxide on overdistention pulmonary hypertension in the isolated sheep lung model. 1995. View abstract
- Limb fractures associated with craneoencephalic trauma. 1991. View abstract