Undergraduate Degree

  • Harvard College , 1958 , Boston , MA

Medical School

  • New York University School of Medicine , 1962 , New York , NY


  • Bellevue Hospital , 1963 , New York , NY


  • Boston Children's Hospital , 1967 , Boston , MA


Research - Nutrition/Cystic Fibrosis and Gastroenterology
  • Boston Children's Hospital , 1969 , Boston , MA


Postdoctoral; Biology and Nutrition
  • Massachusetts Institute of Technology , 1969 , Boston , MA


  • Boston Children's Hospital, Harvard Medical School, Massachusetts General Hospital , 1970 , Boston , MA


Research - Medicine
  • Harvard Medical School , 1970 , Boston , MA


  • American Board of Pediatrics, Pediatric Gastroenterology


Publications powered by Harvard Catalyst Profiles

  1. DIGEST: Developing innovative gastroenterology specialty training. J Cyst Fibros. 2021 07; 20(4):586-590. View abstract
  2. Concordance between gene expression in peripheral whole blood and colonic tissue in children with inflammatory bowel disease. PLoS One. 2019; 14(10):e0222952. View abstract
  3. Differences in DNA Methylation and Functional Expression in Lactase Persistent and Non-persistent Individuals. Sci Rep. 2018 04 04; 8(1):5649. View abstract
  4. Risk factors for low bone mineral density in pediatric inflammatory bowel disease: the positive role of physical activity. Eur J Gastroenterol Hepatol. 2018 Apr; 30(4):471-476. View abstract
  5. Chapter 4. The Relationship Between the European and North American Societies for Pediatric Gastroenterology, Hepatology and Nutrition. J Pediatr Gastroenterol Nutr. 2018 04; 66 Suppl 1:S44-S53. View abstract
  6. Approach to chronic abdominal pain in Cystic Fibrosis. J Cyst Fibros. 2017 Nov; 16 Suppl 2:S24-S31. View abstract
  7. The Utility of the Systemic Inflammatory Respsonse Syndrome Score on Admission in Children With Acute Pancreatitis. Pancreas. 2017 01; 46(1):106-109. View abstract
  8. Trends in Pharmacologic Interventions for Preventing Recurrence of Crohn's Disease After Ileocolonic Surgery. Inflamm Bowel Dis. 2016 10; 22(10):2432-41. View abstract
  9. 50 Years Ago in TheJournal ofPediatrics: Macroscopic Cysts of the Pancreas in a Case of Cystic Fibrosis. J Pediatr. 2016 09; 176:133. View abstract
  10. Functional significance of single nucleotide polymorphisms in the lactase gene in diverse US patients and evidence for a novel lactase persistence allele at -13909 in those of European ancestry. J Pediatr Gastroenterol Nutr. 2015 Feb; 60(2):182-91. View abstract
  11. Potential role of IGF-1 z score to predict permanent linear growth impairment in children with IBD. J Pediatr Gastroenterol Nutr. 2014 Apr; 58(4):472-6. View abstract
  12. Acute cognitive and behavioral effects of systemic corticosteroids in children treated for inflammatory bowel disease. J Int Neuropsychol Soc. 2013 Jan; 19(1):96-109. View abstract
  13. Transcriptional intermediary factor 1? binds to the anaphase-promoting complex/cyclosome and promotes mitosis. Oncogene. 2013 Sep 26; 32(39):4622-33. View abstract
  14. Prevalence and risk factors for hypovitaminosis D in young patients with inflammatory bowel disease. J Pediatr Gastroenterol Nutr. 2011 Oct; 53(4):361-4. View abstract
  15. Efficacy and harms of nasal calcitonin in improving bone density in young patients with inflammatory bowel disease: a randomized, placebo-controlled, double-blind trial. Am J Gastroenterol. 2011 Aug; 106(8):1527-43. View abstract
  16. Intestinal ferroportin expression in pediatric Crohn's disease. Inflamm Bowel Dis. 2011 Feb; 17(2):524-31. View abstract
  17. Characterization of expression in mice of a transgene containing 3.3 kb of the human lactase-phlorizin hydrolase (LPH) 5' flanking sequence. Dig Dis Sci. 2011 Jan; 56(1):59-69. View abstract
  18. Final adult height of children with inflammatory bowel disease is predicted by parental height and patient minimum height Z-score. Inflamm Bowel Dis. 2010 Oct; 16(10):1669-77. View abstract
  19. Association of linear growth impairment in pediatric Crohn's disease and a known height locus: a pilot study. Ann Hum Genet. 2010 Nov; 74(6):489-97. View abstract
  20. Developmental expression of Eph and ephrin family genes in mammalian small intestine. Dig Dis Sci. 2010 Sep; 55(9):2478-88. View abstract
  21. Common variants at five new loci associated with early-onset inflammatory bowel disease. Nat Genet. 2009 Dec; 41(12):1335-40. View abstract
  22. Established genetic risk factors do not distinguish early and later onset Crohn's disease. Inflamm Bowel Dis. 2009 Oct; 15(10):1508-14. View abstract
  23. Immune response to influenza vaccine in children with inflammatory bowel disease. Am J Gastroenterol. 2009 Feb; 104(2):444-53. View abstract
  24. Profile of depression in adolescents with inflammatory bowel disease: implications for treatment. Inflamm Bowel Dis. 2009 Jan; 15(1):69-74. View abstract
  25. Adenovirus 5 E1A is responsible for increased expression of insulin receptor substrate 4 in established adenovirus 5-transformed cell lines and interacts with IRS components activating the PI3 kinase/Akt signalling pathway. Oncogene. 2009 Feb 05; 28(5):686-97. View abstract
  26. Does inflammatory bowel disease develop in infants? Inflamm Bowel Dis. 2008 Oct; 14 Suppl 2:S6-8. View abstract
  27. Genetic variants in the autophagy pathway contribute to paediatric Crohn's disease. Gut. 2008 Sep; 57(9):1336-7; author reply 1337. View abstract
  28. GATA4 mediates gene repression in the mature mouse small intestine through interactions with friend of GATA (FOG) cofactors. Dev Biol. 2008 Oct 01; 322(1):179-89. View abstract
  29. Vitamin D status in gastrointestinal and liver disease. Curr Opin Gastroenterol. 2008 Mar; 24(2):176-83. View abstract
  30. Lactose malabsorption. Curr Treat Options Gastroenterol. 2008 Feb; 11(1):19-25. View abstract
  31. Lactose and lactase--who is lactose intolerant and why? J Pediatr Gastroenterol Nutr. 2007 Dec; 45 Suppl 2:S131-7. View abstract
  32. The prevalence and geographic distribution of Crohn's disease and ulcerative colitis in the United States. Clin Gastroenterol Hepatol. 2007 Dec; 5(12):1424-9. View abstract
  33. Intercenter variation in initial management of children with Crohn's disease. Inflamm Bowel Dis. 2007 Jul; 13(7):890-5. View abstract
  34. C-terminal-binding protein interacting protein binds directly to adenovirus early region 1A through its N-terminal region and conserved region 3. Oncogene. 2007 Nov 22; 26(53):7467-79. View abstract
  35. Lactose Intolerance in Children. Pediatric Views. 2007; 3. View abstract
  36. Gata4 and Hnf1alpha are partially required for the expression of specific intestinal genes during development. Am J Physiol Gastrointest Liver Physiol. 2007 May; 292(5):G1302-14. View abstract
  37. Impaired intestinal iron absorption in Crohn's disease correlates with disease activity and markers of inflammation. Inflamm Bowel Dis. 2006 Dec; 12(12):1101-6. View abstract
  38. Report on the vitamin D status of adult and pediatric patients with inflammatory bowel disease and its significance for bone health and disease. Inflamm Bowel Dis. 2006 Dec; 12(12):1162-74. View abstract
  39. Vitamin D status in children and young adults with inflammatory bowel disease. Pediatrics. 2006 Nov; 118(5):1950-61. View abstract
  40. Tacrolimus-associated eosinophilic gastroenterocolitis in pediatric liver transplant recipients: role of potential food allergies in pathogenesis. Pediatr Transplant. 2006 Sep; 10(6):730-5. View abstract
  41. Hepatocyte nuclear factor-1alpha is required for expression but dispensable for histone acetylation of the lactase-phlorizin hydrolase gene in vivo. Am J Physiol Gastrointest Liver Physiol. 2006 May; 290(5):G1016-24. View abstract
  42. Developmental and regional expression and localization of mRNAs encoding proteins involved in RNA translocation. J Histochem Cytochem. 2005 Dec; 53(12):1501-9. View abstract
  43. Pediatric inflammatory bowel disease: what children can teach adults. Inflamm Bowel Dis. 2005 Jun; 11(6):519-27. View abstract
  44. Effect of recombinant growth hormone treatment on children with Crohn's disease and short stature: a pilot study. Inflamm Bowel Dis. 2005 May; 11(5):435-41. View abstract
  45. Introduction: First International Symposium on: pediatric inflammatory bowel disease: September 16-18, 2003; Irvington, Virginia, U.S.A. J Pediatr Gastroenterol Nutr. 2005 Apr; 40 Suppl 1:S1. View abstract
  46. Inverting the therapeutic triangle. J Pediatr Gastroenterol Nutr. 2005 Apr; 40 Suppl 1:S50-2. View abstract
  47. A review of activity indices and end points for clinical trials in children with Crohn's disease. Inflamm Bowel Dis. 2005 Feb; 11(2):185-96. View abstract
  48. Regulatory regions in the rat lactase-phlorizin hydrolase gene that control cell-specific expression. J Pediatr Gastroenterol Nutr. 2004 Sep; 39(3):275-85. View abstract
  49. Pediatric inflammatory bowel disease. Curr Opin Gastroenterol. 2004 Jul; 20(4):333-40. View abstract
  50. Complex regulation of the lactase-phlorizin hydrolase promoter by GATA-4. Am J Physiol Gastrointest Liver Physiol. 2004 Oct; 287(4):G899-909. View abstract
  51. Steriod Therapy in the Age of Infliximab (IFX): Intermediate & 1 Year Outcome in Newly Diagnosed Children with Crohn's Disease (CD): Experience of the Pediatric IBD Collaborative Research Group. Gastroenterology. 2004; 364:W-1394. View abstract
  52. Developmental Expression of mRNAs Encoding Proteins Involved in RNA Translocation. Gastroenterology. 2004; 364:M-969. View abstract
  53. Serologic prevalence of antibodies to Helicobacter pylori in internationally adopted children. Helicobacter. 2003 Jun; 8(3):173-8. View abstract
  54. Changing genes; losing lactase. Gut. 2003 May; 52(5):617-9. View abstract
  55. Treatment of inflammatory bowel disease in childhood: best available evidence. Inflamm Bowel Dis. 2003 Jan; 9(1):34-58. View abstract
  56. Hepatocyte nuclear factor-1a (HNF-1a) differentially regulates lactase-phlorizin hydrolase (LPH) gene expression during weaning in mice. Gastroenterology. 2003; 124:A-91. View abstract
  57. mRNA localization in polarized intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol. 2003 Apr; 284(4):G722-7. View abstract
  58. Novel interaction at the Cdx-2 binding sites of the lactase-phlorizin hydrolase promoter. Biochem Biophys Res Commun. 2002 Dec 13; 299(4):587-93. View abstract
  59. Shwachman-Diamond syndrome: report from an international conference. J Pediatr. 2002 Aug; 141(2):266-70. View abstract
  60. Hepatocyte nuclear factor-1 alpha, GATA-4, and caudal related homeodomain protein Cdx2 interact functionally to modulate intestinal gene transcription. Implication for the developmental regulation of the sucrase-isomaltase gene. J Biol Chem. 2002 Aug 30; 277(35):31909-17. View abstract
  61. Physical interaction between GATA-5 and hepatocyte nuclear factor-1alpha results in synergistic activation of the human lactase-phlorizin hydrolase promoter. J Biol Chem. 2002 Aug 02; 277(31):27659-67. View abstract
  62. Research agenda for pediatric gastroenterology, hepatology and nutrition: chronic inflammatory bowel disease. Report of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition for the Children's Digestive Health and Nutrition Foundation. J Pediatr Gastroenterol Nutr. 2002; 35 Suppl 3:S286-90. View abstract
  63. Research agenda for pediatric gastroenterology, hepatology and nutrition: introduction. Report of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition for the Children's Digestive Health and Nutrition Foundation. J Pediatr Gastroenterol Nutr. 2002; 35 Suppl 3:S235-6. View abstract
  64. Genetics of gastrointestinal and hepatobiliary disorders: Working Group Report of the First World Congress of Pediatric Gastroenterology, Hepatology, and Nutrition. J Pediatr Gastroenterol Nutr. 2002; 35 Suppl 2:S118-27. View abstract
  65. Friend of GATA (FOG) cofactors modulate the GATA activation of the human lactase-phlorizin hydrolase (LPH) promoter. Gastroenterology. 2002; 122:A-680. View abstract
  66. Section Editor's Commentary. Anti-TNF Therapies Have Eliminated the Need for Steroids in Pediatric Crohn's Disease. Inflamm Bowel Dis. 2001 Nov; 7(4):345-346. View abstract
  67. Recombinant adenovirus coexpressing covalent peptide/MHC class II complex and B7-1: in vitro and in vivo activation of myelin basic protein-specific T cells. J Immunol. 2001 Aug 01; 167(3):1297-305. View abstract
  68. Differential activation of intestinal gene promoters: functional interactions between GATA-5 and HNF-1 alpha. Am J Physiol Gastrointest Liver Physiol. 2001 Jul; 281(1):G69-84. View abstract
  69. Structural determinants outside the PXDLS sequence affect the interaction of adenovirus E1A, C-terminal interacting protein and Drosophila repressors with C-terminal binding protein. Biochim Biophys Acta. 2001 Mar 09; 1546(1):55-70. View abstract
  70. Methodologic issues in the conduct and interpretation of pediatric effectiveness research. Ambul Pediatr. 2001 Jan-Feb; 1(1):63-70. View abstract
  71. Structural determinants in adenovirus 12 E1A involved in the interaction with C-terminal binding protein 1. Virology. 2000 Nov 10; 277(1):156-66. View abstract
  72. Regulation of the 26S proteasome by adenovirus E1A. EMBO J. 2000 Sep 01; 19(17):4759-73. View abstract
  73. Consequences of disruption of the interaction between p53 and the larger adenovirus early region 1B protein in adenovirus E1 transformed human cells. Oncogene. 2000 Jan 20; 19(3):452-62. View abstract
  74. Brush border myosin I (BBMI): a basally localized transcript in human jejunal enterocytes. J Histochem Cytochem. 2000 Jan; 48(1):89-94. View abstract
  75. Gene therapy for gastrointestinal disorders: just around the corner? J Pediatr Gastroenterol Nutr. 1999 Oct; 29(4):375-6. View abstract
  76. Propranolol in prevention of portal hypertensive hemorrhage in children: a pilot study. J Pediatr Gastroenterol Nutr. 1999 Jul; 29(1):12-7. View abstract
  77. The fate of E- and P-cadherin during the early stages of apoptosis. Cell Death Differ. 1999 Apr; 6(4):377-86. View abstract
  78. The replicative capacities of large E1B-null group A and group C adenoviruses are independent of host cell p53 status. J Virol. 1999 Mar; 73(3):2074-83. View abstract
  79. Development of the human gastrointestinal tract: twenty years of progress. Gastroenterology. 1999 Mar; 116(3):702-31. View abstract
  80. The structure of the site on adenovirus early region 1A responsible for binding to TATA-binding protein determined by NMR spectroscopy. J Biol Chem. 1999 Feb 05; 274(6):3503-12. View abstract
  81. Definition of a major p53 binding site on Ad2E1B58K protein and a possible nuclear localization signal on the Ad12E1B54K protein. Oncogene. 1999 Jan 28; 18(4):955-65. View abstract
  82. Adenovirus early region 1A protein binds to mammalian SUG1-a regulatory component of the proteasome. Oncogene. 1999 Jan 14; 18(2):449-58. View abstract
  83. Assignment of the yeast APG5 human homologue APG5L to chromosome band 6q21 by fluorescence in situ hybridisation. Cytogenet Cell Genet. 1999; 87(3-4):213-4. View abstract
  84. Unit 35: Development of the Human GI System. 1999. View abstract
  85. Structural determinants present in the C-terminal binding protein binding site of adenovirus early region 1A proteins. J Biol Chem. 1998 Aug 14; 273(33):20867-76. View abstract
  86. Specific cleavage of gamma catenin by caspases during apoptosis. FEBS Lett. 1998 Aug 14; 433(1-2):51-7. View abstract
  87. Defective intracellular processing of lactase-phlorizin hydrolase protein in rats prenatally exposed to ethanol. Alcohol Clin Exp Res. 1998 Aug; 22(5):1177-83. View abstract
  88. Management of severe colitis/ileocolitis. Inflamm Bowel Dis. 1998 Aug; 4(3):225-7. View abstract
  89. Three distinct messenger RNA distribution patterns in human jejunal enterocytes. Gastroenterology. 1998 Jul; 115(1):86-92. View abstract
  90. More on the obesity problem. N Engl J Med. 1998 Jun 04; 338(23):1702. View abstract
  91. Human cells arrest in S phase in response to adenovirus 12 E1A. Virology. 1998 May 10; 244(2):330-42. View abstract
  92. Regeneration of the binding properties of adenovirus 12 early region 1A proteins after preparation under denaturing conditions. Virology. 1998 Apr 25; 244(1):230-42. View abstract
  93. Homology between a human apoptosis specific protein and the product of APG5, a gene involved in autophagy in yeast. FEBS Lett. 1998 Apr 03; 425(3):391-5. View abstract
  94. The Shwachman Award of the North American Society for Pediatric Gastroenterology and Nutrition presentation. J Pediatr Gastroenterol Nutr. 1998 Apr; 26(4):371-5. View abstract
  95. Asymmetrical localization of mRNAs in enterocytes of human jejunum. J Histochem Cytochem. 1998 Mar; 46(3):335-43. View abstract
  96. Treatment of extraintestinal manifestations of inflammatory bowel disease. Inflamm Bowel Dis. 1998 Feb; 4(1):72; discussion 73. View abstract
  97. Advances in nutrition and gastroenterology: summary of the 1997 A.S.P.E.N. Research Workshop. JPEN J Parenter Enteral Nutr. 1998 Jan-Feb; 22(1):3-13. View abstract
  98. Pancreatic acinar cell clusters in pediatric gastric mucosa. Am J Surg Pathol. 1998 Jan; 22(1):100-5. View abstract
  99. Differential effects of BCL-2 on survival and proliferation of human B-lymphoma cells following gamma-irradiation. Oncogene. 1997 Oct 09; 15(15):1815-22. View abstract
  100. Rat lactase-phlorizin hydrolase/human growth hormone transgene is expressed on small intestinal villi in transgenic mice. Gastroenterology. 1997 Sep; 113(3):844-55. View abstract
  101. Adenovirus type 12 early region 1B 54K protein significantly extends the life span of normal mammalian cells in culture. J Virol. 1997 Sep; 71(9):6629-40. View abstract
  102. Pancreatic metaplasia of the gastric mucosa in pediatric patients. Am J Gastroenterol. 1997 Sep; 92(9):1553-6. View abstract
  103. Differentiation is inhibited and a senescence pathway is activated when simian virus 40 tsA 58-transformed human retinoblasts are grown at the restrictive temperature. Cell Growth Differ. 1997 Jul; 8(7):763-71. View abstract
  104. High-dose pancreatic-enzyme supplements and fibrosing colonopathy in children with cystic fibrosis. N Engl J Med. 1997 May 01; 336(18):1283-9. View abstract
  105. Increased C/EBP in fetal rat small intestine precedes initiation of differentiation marker mRNA synthesis. Am J Physiol. 1997 Mar; 272(3 Pt 1):G534-44. View abstract
  106. The expression of MDM2 and other p53-regulated proteins in the tissues of the developing rat. Biochim Biophys Acta. 1997 Feb 28; 1350(3):306-16. View abstract
  107. Prenatal ethanol exposure alters the expression of intestinal hydrolase mRNAs in newborn rats. Alcohol Clin Exp Res. 1996 Dec; 20(9):1662-8. View abstract
  108. A lamb-meat-based formula for infants allergic to casein hydrolysate formulas. Clin Pediatr (Phila). 1996 Oct; 35(10):491-5. View abstract
  109. Therapeutic strategies for pediatric Crohn disease. Clin Invest Med. 1996 Oct; 19(5):373-80. View abstract
  110. Repression of apoptosis in human B-lymphoma cells by CD40-ligand and Bcl-2: relationship to the cell-cycle and role of the retinoblastoma protein. Oncogene. 1996 Jul 18; 13(2):373-9. View abstract
  111. Biliary atresia: current concepts and research directions. Summary of a symposium. Hepatology. 1996 Jun; 23(6):1682-92. View abstract
  112. Quantitative analysis of lactase-phlorizin hydrolase expression in the absorptive enterocytes of newborn rat small intestine. J Cell Physiol. 1996 May; 167(2):341-8. View abstract
  113. Combined use of cyclosporine and azathioprine or 6-mercaptopurine in pediatric inflammatory bowel disease. J Pediatr Gastroenterol Nutr. 1996 Apr; 22(3):296-302. View abstract
  114. Control of p53 expression by adenovirus 12 early region 1A and early region 1B 54K proteins. Virology. 1996 Apr 01; 218(1):23-34. View abstract
  115. Cellular consequences of thrombin-receptor activation. Biochem J. 1996 Jan 15; 313 ( Pt 2):353-68. View abstract
  116. Medical therapy for children with inflammatory bowel disease. Inflamm Bowel Dis. 1996; 2(4):269-75. View abstract
  117. Use of pancreatic enzyme supplements for patients with cystic fibrosis in the context of fibrosing colonopathy. Consensus Committee. J Pediatr. 1995 Nov; 127(5):681-4. View abstract
  118. Verification of the lactase site of rat lactase-phlorizin hydrolase by site-directed mutagenesis. Gastroenterology. 1995 Oct; 109(4):1234-40. View abstract
  119. Inflammatory bowel disease in the pediatric patient. Gastroenterol Clin North Am. 1995 Sep; 24(3):613-32. View abstract
  120. Ras binding to a C-terminal region of GAP. FEBS Lett. 1995 Jul 17; 368(2):297-303. View abstract
  121. The high levels of p53 present in adenovirus early region 1-transformed human cells do not cause up-regulation of MDM2 expression. Virology. 1995 Jul 10; 210(2):323-34. View abstract
  122. Regulation of neurite outgrowth from differentiated human neuroepithelial cells: a comparison of the activities of prothrombin and thrombin. Biochem J. 1995 Jun 15; 308 ( Pt 3):965-73. View abstract
  123. A novel protein expressed in mammalian cells undergoing apoptosis. Exp Cell Res. 1995 Jun; 218(2):439-51. View abstract
  124. Further characterization of the 5'-flanking region of the rat lactase-phlorizin hydrolase gene. Biochem Biophys Res Commun. 1995 Apr 26; 209(3):989-95. View abstract
  125. The quaternary structure of the adenovirus 12 early region 1B 54K protein. Virology. 1995 Feb 20; 207(1):255-9. View abstract
  126. Intestinal brush border glycohydrolases: structure, function, and development. Crit Rev Biochem Mol Biol. 1995; 30(3):197-262. View abstract
  127. Lactose intolerance and lactase deficiency in children. Curr Opin Pediatr. 1994 Oct; 6(5):562-7. View abstract
  128. Transcriptional regulation of intestinal hydrolase biosynthesis during postnatal development in rats. Am J Physiol. 1994 Oct; 267(4 Pt 1):G584-94. View abstract
  129. Enhanced expression of p53 in human cells infected with mutant adenoviruses. Virology. 1994 Sep; 203(2):229-40. View abstract
  130. Gene therapy for exocrine pancreatic insufficiency. Gastroenterology. 1994 Jun; 106(6):1711-3. View abstract
  131. Structure around the cleavage site in the thrombin receptor determined by NMR spectroscopy. Biochemistry. 1994 May 24; 33(20):6063-73. View abstract
  132. Restriction of lactase gene expression along the proximal-to-distal axis of rat small intestine occurs during postnatal development. Gastroenterology. 1994 May; 106(5):1223-32. View abstract
  133. Mammalian Brush Border Membrane Proteins II. 1994. View abstract
  134. Growth failure in children with inflammatory bowel disease: a prospective study. Gastroenterology. 1993 Sep; 105(3):681-91. View abstract
  135. Peptide mimetics of nucleotide phosphate binding sites. Biochem Soc Trans. 1993 Aug; 21 ( Pt 3)(3):267S. View abstract
  136. Olsalazine versus sulfasalazine in mild to moderate childhood ulcerative colitis: results of the Pediatric Gastroenterology Collaborative Research Group Clinical Trial. J Pediatr Gastroenterol Nutr. 1993 Jul; 17(1):32-8. View abstract
  137. Overexpression of wild-type p53 and c-Myc in human fetal cells transformed with adenovirus early region 1. Virology. 1993 Apr; 193(2):579-91. View abstract
  138. Identification of nonsteroidal antiinflammatory drug-induced gastroduodenal injury in children with juvenile rheumatoid arthritis. J Pediatr. 1993 Apr; 122(4):647-9. View abstract
  139. Vitronectin is the major serum protein essential for NGF-mediated neurite outgrowth from PC12 cells. Exp Cell Res. 1992 Oct; 202(2):337-44. View abstract
  140. Lactase gene expression during early development of rat small intestine. Gastroenterology. 1992 Oct; 103(4):1154-61. View abstract
  141. Developmental regulation of the brush border hydrolase lactase. J Pediatr Gastroenterol Nutr. 1992 Aug; 15(2):215-7. View abstract
  142. Vitamin E deficiency and impaired cellular immunity related to intestinal fat malabsorption. Gastroenterology. 1992 Jun; 102(6):2139-42. View abstract
  143. Messenger RNA sorting in enterocytes. Co-localization with encoded proteins. FEBS Lett. 1992 Mar 30; 300(2):183-7. View abstract
  144. Efficacy of cimetidine for gastric acid suppression in pediatric patients. J Pediatr. 1992 Mar; 120(3):474-8. View abstract
  145. Molecular basis of lactase levels in adult humans. J Clin Invest. 1992 Feb; 89(2):480-3. View abstract
  146. Induction of Epstein-Barr virus lytic cycle by tumor-promoting and non-tumor-promoting phorbol esters requires active protein kinase C. J Virol. 1991 Dec; 65(12):6838-44. View abstract
  147. The biochemistry of ras p21. Biochem J. 1991 Nov 01; 279 ( Pt 3):609-31. View abstract
  148. Cortisone and thyroxine modulate intestinal lactase and sucrase mRNA levels and activities in the suckling rat. Biochem Biophys Res Commun. 1991 Oct 15; 180(1):174-80. View abstract
  149. Gastrointestinal Disorders in Adolescents. Adolesc Med. 1991 Oct; 2(3):485-498. View abstract
  150. The human intestinal response to enteral nutrients: a review. J Am Coll Nutr. 1991 Oct; 10(5):500-9. View abstract
  151. Lactose intolerance and the genetic regulation of intestinal lactase-phlorizin hydrolase. FASEB J. 1991 Oct; 5(13):2824-32. View abstract
  152. Modulation of Human Neurite Outgrowth by Serine Proteases: A Comparison of the Interaction of Thrombin and Prothrombin with Glia-Derived Nexin. Eur J Neurosci. 1991 Jul; 3(7):663-668. View abstract
  153. Crohn's disease associated with autoimmune neutropenia. J Clin Gastroenterol. 1991 Jun; 13(3):328-30. View abstract
  154. Development and validation of a pediatric Crohn's disease activity index. J Pediatr Gastroenterol Nutr. 1991 May; 12(4):439-47. View abstract
  155. [Lactose intolerance. II. Current biological viewpoints]. Ned Tijdschr Geneeskd. 1991 Apr 27; 135(17):746-9. View abstract
  156. [Lactose intolerance. I. Clinical aspects, diagnosis and therapy]. Ned Tijdschr Geneeskd. 1991 Apr 27; 135(17):742-6. View abstract
  157. The use of beta-galactosidase fusion proteins encoding the early region 1 transforming proteins of adenovirus type 12 to examine the humoral response in tumour-bearing animals. J Gen Virol. 1991 Apr; 72 ( Pt 4):955-60. View abstract
  158. Clinical aspects of lactose intolerance in children and adults. Scand J Gastroenterol Suppl. 1991; 188:73-80. View abstract
  159. Azathioprine in the treatment of children with inflammatory bowel disease. J Pediatr. 1990 Nov; 117(5):809-14. View abstract
  160. Sensitivity to ionising radiation of transformed human cells containing mutant ras genes. Oncogene. 1990 Aug; 5(8):1159-64. View abstract
  161. The expression of the adenovirus 12 early region 1B 19K protein using a recombinant simian virus 40 system. J Gen Virol. 1990 Aug; 71 ( Pt 8):1713-22. View abstract
  162. Coordinate expression of lactase-phlorizin hydrolase mRNA and enzyme levels in rat intestine during development. J Biol Chem. 1990 Apr 25; 265(12):6978-83. View abstract
  163. Integrated HPV 1 genomes in a human keratinocyte cell line can be transactivated by a SV40/BPV1 recombinant virus which expresses BPV1 E2 proteins. Virology. 1990 Apr; 175(2):508-17. View abstract
  164. Glycosylation of lactase-phlorizin hydrolase in rat small intestine during development. Gastroenterology. 1990 Mar; 98(3):667-75. View abstract
  165. Lactose intolerance. Annu Rev Med. 1990; 41:141-8. View abstract
  166. The expression of the retinoblastoma gene product Rb1 in primary and adenovirus-transformed human cells. Oncogene. 1989 Nov; 4(11):1291-8. View abstract
  167. Further studies of glycosylation and intracellular transport of lactase-phlorizin hydrolase in rat small intestine. Biochem J. 1989 Oct 01; 263(1):249-54. View abstract
  168. New insights into lactase and glycosylceramidase activities of rat lactase-phlorizin hydrolase. Am J Physiol. 1989 Oct; 257(4 Pt 1):G616-23. View abstract
  169. Suckling rat colon synthesizes and processes active lactase-phlorizin hydrolase immunologically identical to that from jejunum. Pediatr Res. 1989 Sep; 26(3):232-6. View abstract
  170. Conformational changes occurring in N-ras p21 in response to binding of guanine nucleotide and metal ions probed by proteolysis performed under controlled conditions. FEBS Lett. 1989 Aug 14; 253(1-2):281-6. View abstract
  171. Modulation of morphological differentiation of human neuroepithelial cells by serine proteases: independence from blood coagulation. EMBO J. 1989 Aug; 8(8):2209-15. View abstract
  172. Phosphorylation of the human papillomavirus type 1 E4 proteins in vivo and in vitro. Virology. 1989 May; 170(1):201-13. View abstract
  173. The expression of Ad12 E1B 19K protein on the surface of adenovirus transformed and infected human cells. Oncogene. 1989 Apr; 4(4):489-97. View abstract
  174. Acylation of viral and eukaryotic proteins. Biochem J. 1989 Mar 15; 258(3):625-38. View abstract
  175. The binding of guanine nucleotide to N-ras p21--a phosphorous and proton magnetic resonance study. Oncogene. 1989 Mar; 4(3):355-61. View abstract
  176. Purification of a serum factor which reverses dibutyryl cAMP induced differentiation. Cell Signal. 1989; 1(3):269-81. View abstract
  177. A region of the Epstein-Barr virus nuclear antigen leader protein and adenovirus E1A are identical. Oncogene. 1988 Dec; 3(6):729-30. View abstract
  178. Intracellular calcium receptor mechanisms in muscle and nerve. Biochem Soc Trans. 1988 Aug; 16(4):520-3. View abstract
  179. Differentiation of normal and adenovirus-12 E1 transformed human embryo retinal cells. Exp Eye Res. 1988 Jul; 47(1):123-33. View abstract
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