EDUCATION

Graduate Degree

Immunology
  • University of Oxford , 2006 , Oxford , United Kingdom

Medical School

  • Washington University School of Medicine , 2008 , St. Louis , MO

Residency

Pediatrics
  • Boston Combined Residency Program (BCRP) , 2011 , Boston , MA

Fellowship

Critical Care
  • Boston Children's Hospital , 2015 , Boston , MA

CERTIFICATIONS

  • American Board of Pediatrics, General Pediatrics
  • American Board of Pediatrics, Critical Care Medicine

PUBLICATIONS

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  1. Inflammation resolution circuits are uncoupled in acute sepsis and correlate with clinical severity. JCI Insight. 2021 Aug 09; 6(15). View abstract
  2. Invasive and noninvasive ventilation strategies for acute respiratory failure in children with coronavirus disease 2019. Curr Opin Pediatr. 2021 06 01; 33(3):311-318. View abstract
  3. Human NK Cell Cytoskeletal Dynamics and Cytotoxicity Are Regulated by LIM Kinase. J Immunol. 2020 08 01; 205(3):801-810. View abstract
  4. Leukocyte function assessed via serial microlitre sampling of peripheral blood from sepsis patients correlates with disease severity. Nat Biomed Eng. 2019 12; 3(12):961-973. View abstract
  5. Non-type 2 inflammation in severe asthma is propelled by neutrophil cytoplasts and maintained by defective resolution. Allergol Int. 2019 Apr; 68(2):143-149. View abstract
  6. Neutrophil cytoplasts induce TH17 differentiation and skew inflammation toward neutrophilia in severe asthma. Sci Immunol. 2018 08 03; 3(26). View abstract
  7. ALX receptor ligands define a biochemical endotype for severe asthma. JCI Insight. 2018 03 22; 3(6). View abstract
  8. Better Late Than Never? Deferred Consent for Minimal Risk Research in the ICU. Crit Care Med. 2017 09; 45(9):1571-1572. View abstract
  9. ALX receptor ligands define a biochemical endotype for severe asthma. JCI Insight. 2017 Jul 20; 2(14). View abstract
  10. Bronchoprotective mechanisms for specialized pro-resolving mediators in the resolution of lung inflammation. Mol Aspects Med. 2017 Dec; 58:44-56. View abstract
  11. Natural killer cell-mediated inflammation resolution is disabled in severe asthma. Sci Immunol. 2017 Mar 10; 2(9). View abstract
  12. Mast cell-derived neurotrophin 4 mediates allergen-induced airway hyperinnervation in early life. Mucosal Immunol. 2016 11; 9(6):1466-1476. View abstract
  13. DHA- and EPA-derived resolvins, protectins, and maresins in airway inflammation. Eur J Pharmacol. 2016 Aug 15; 785:144-155. View abstract
  14. Pulmonary hypertension associated with scurvy and vitamin deficiencies in an autistic child. Pediatrics. 2013 Dec; 132(6):e1699-703. View abstract
  15. Polyfunctional T cell responses are a hallmark of HIV-2 infection. Eur J Immunol. 2008 Feb; 38(2):350-63. View abstract
  16. Effects of cryopreservation on CD4+ CD25+ T cells of HIV-1 infected individuals. J Clin Lab Anal. 2008; 22(3):153-8. View abstract
  17. Dendritic cells are less susceptible to human immunodeficiency virus type 2 (HIV-2) infection than to HIV-1 infection. J Virol. 2007 Dec; 81(24):13486-98. View abstract
  18. Maintenance of HIV-specific CD4+ T cell help distinguishes HIV-2 from HIV-1 infection. J Immunol. 2006 Jun 01; 176(11):6973-81. View abstract
  19. Analysis of human immunodeficiency virus cytopathicity by using a new method for quantitating viral dynamics in cell culture. J Virol. 2005 Apr; 79(7):4025-32. View abstract
  20. Cytopathic killing of peripheral blood CD4(+) T lymphocytes by human immunodeficiency virus type 1 appears necrotic rather than apoptotic and does not require env. J Virol. 2002 May; 76(10):5082-93. View abstract