Glomuvenous Malformation

What is a glomuvenous malformation?

A glomuvenous malformation (GVM) is a type of vascular malformation formed by an abnormal growth of blood vessels and the presence of glomus cells in the wall of the malformation.

While they may be present at birth, they can also appear at any age and tend to be hereditary. Without treatment, GVMs change in appearance over time, becoming thicker and darker in color.

How we care for glomuvenous malformation

We treat children with glomuvenous malformations in our Vascular Anomalies Center, considered a premier center in the world for all types of vascular malformations.

Families choose us because we offer:

  • Nationally-recognized expertise: Families travel to us from all over the country because of our reputation for experience. As a national referral center, we have diagnosed and treated more cases of glomuvenous malformation than any other hospital.
  • Comprehensive team approach: At the Vascular Anomalies Center, patients and their families benefit from a team of specialists working together to develop a customized treatment plan for your child. Our clinic brings together the expertise of many fields including hematology/oncology, dermatology, interventional radiology (minimally invasive treatments) surgery.
  • Expert diagnosis: Some cases of GVM may be misdiagnosed as hemangioma or venous malformation. We offer a definitive diagnosis that determines the exact location and depth of the lesions for the most targeted treatment possible. Learn more about glomuvenous malformation diagnosis.
  • Leaders in advanced treatments: Members of our team have unmatched experience with many of the top GVM treatments. Our hematologists were among the first to study and prescribe medications such as sirolimus for vascular malformations and are experts in precise dosing for the best possible results.

Our areas of innovation for glomuvenous malformation

At Boston Children’s Hospital, our Vascular Anomalies team is known for its expertise in diagnosing and treating multiple and extensive glomuvenous malformations in infants and children of all ages.

For decades, our Vascular Anomalies Center has collaborated with genetic researchers in Belgium to understand the genetic causes of vascular malformations. This work led to the discovery of the gene responsible for glomuvenous malformation. Read more about research and innovation at the Vascular Anomalies Center.