Gliomatosis Cerebri

What is gliomatosis cerebri?

Gliomatosis cerebri is a rare and highly aggressive form of malignant astrocytic tumor. It most commonly presents as a diffusely infiltrating glial tumor of the cerebral cortex.

  • Gliomatosis cerebri is a type of astrocytoma, which is a sub-type of glioma. A glioma is a type of brain tumor that originates from glial cells, which support and nourish neurons in the brain.
  • Gliomatosis cerebri is characterized by scattered and widespread tumor cells that cause multiple parts of the brain to enlarge.
  • Because this type of tumor is so diffuse, it can be difficult to treat. These tumors usually progress like a glioblastoma multiforme (the most malignant form of brain tumor).

How Dana-Farber/Boston Children's approaches gliomatosis cerebri

Children and adolescents with gliomatosis cerebri are treated through our Glioma Program, one of the largest and most experienced pediatric glioma programs in the world, and part of the Dana-Farber/Boston Children’s Brain Tumor Center.

Our glioma specialists — a team of neuro-oncologists, surgeons, pathologists and radiation oncologists — focus solely on the care of children diagnosed with gliomas. The Glioma Program also offers families the chance to have their child's tumor molecularly profiled (as long as a biopsy can be taken), which may help identify opportunities for targeted treatment.

Find in-depth information on gliomatosis cerebri on the Dana-Farber/Boston Children's website, including details on gliomatosis cerebri symptoms, treatment and more.

International Gliomatosis Cerebri Platform

The International Gliomatosis Cerebri Platform is run by Dana-Farber/Boston Children's along with an international network of experts studying and treating gliomatosis cerebri. The platform is intended to drive and support translational discovery and clinical research, while serving as a center of communication for gliomatosis cerebri scientists. The site includes a messaging platform and a running list of information on tissue, cell lines, and models available to potential collaborators.