Glioblastoma Multiforme | Symptoms & Causes

What are the symptoms of glioblastoma multiforme?

Brain tumors can cause a variety of symptoms in children based primarily on the location of the tumor, its size and whether it has spread. Keep in mind that the symptoms of a brain tumor may resemble other more common conditions or medical problems. It is important to consult your child's physician for a diagnosis.

Most glioblastoma multiforme (GBM) symptoms result from increased pressure within the head. Other symptoms relate to the tumor’s specific location, rate of growth and associated inflammation. Symptoms can develop slowly over time or begin very suddenly. The most common symptoms include:

  • headache and lethargy 
  • seizures
  • compression of surrounding brain structures

What causes GBMs?

There are certain hereditary conditions that are linked to these tumors. GBMs can occur with increased frequency in families with conditions including Li-Fraumeni syndrome, hereditary nonpolyposis colon cancer, tuberous sclerosis and neurofibromatosis Type 1.