Congenital Sideroblastic Anemia | Symptoms & Causes

What are the symptoms of congenital sideroblastic anemia?

The symptoms and signs of congenital sideroblastic anemia (CSA) in children are primarily related to the anemia and its severity:

  • fatigue
  • jaundice
  • irritability
  • exercise/feeding intolerance
  • exertional dyspnea
  • headache, vertigo

Some forms of CSA are associated with other symptoms or signs outside the blood system. These are referred to as syndromic CSAs. The associated symptoms can include:

  • developmental delay
  • deafness
  • vision loss
  • muscle dysfunction (heart muscle and/or other muscles)
  • organ failure (e.g. kidney and/or liver)
  • immunodeficiency
  • fevers
  • acidosis

What are the causes of CSA? 

Each of the CSA types require testing to isolate. It is important to understand that some symptoms of  CSA may resemble those of other more common medical problems or other blood disorders. Because some of these symptoms can also point to other conditions, and because anemia itself can be a symptom of another medical problem, it’s important to have your child evaluated by a qualified medical professional for an accurate diagnosis and prompt treatment.