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The Division of Endocrinology at Boston Children's Hospital offers a fertile training ground for young physicians and researchers to receive a rich and varied educational experience, drawing on our close relationship with other world-class clinical teachers and researchers in the Harvard Medical School community.
We play a major role in training pediatric residents in the Boston Combined Residency Training to become the next generation of primary care pediatricians, subspecialists and leaders in academic centers. Children's residents have voted the Division of Endocrinology's educational program to be among the best at the hospital.
Boston Children's offers an unparalleled opportunity for studying pediatric endocrinology within a strong general pediatric setting.
The Training Program in Pediatric Endocrinology at Boston Children's Hospital, Harvard Medical School consists of a comprehensive clinical and research experience spanning three years. This program is intended for physicians who desire to pursue a career in academic medicine that combines both clinical and research activities, and to prepare future academic leaders in endocrinology and diabetes. The clinical management of outpatient and inpatient endocrine disorders, including diabetes, is emphasized in the first year. The second and third years are primarily devoted to in-depth investigation of an area of basic or clinical research under the supervision of a faculty preceptor. Each year, the program accepts three first year fellows.
The First Year
As both an active primary care hospital and a major regional, national, and international tertiary/ quaternary care center, Children’s Hospital has a large and varied patient population with an unsurpassed diversity of endocrine diseases and their complications.
In the first year, fellows divide their time between monthly inpatient and outpatient rotations:
On the inpatient Endocrinology and Diabetes Services, the fellows work closely with Endocrinology Division faculty to evaluate and manage all endocrine and diabetes consultations within Children’s Hospital, as well as in the newborn nurseries and neonatal intensive care units at the adjacent Brigham and Women's (BWH) and Beth Israel Deaconess Medical Center (BIDMC) Hospitals. Fellow also directly supervise the care of all endocrine and diabetes patients admitted to the Children's Hospital Endocrine Service. While on the inpatient rotation, fellows maintain one half-day clinic session per week.
On the outpatient service, the fellows conduct 2-3 half-day clinics each week that exposes them to a wide range of pediatric endocrine disorders including type 1 and type 2 diabetes, puberty and growth disorders, obesity, metabolic bone diseases, reproductive endocrinology, thyroid and thyroid nodules, disorders of sexual differentiation, transgender medicine and brain tumor/neuroendocrine dysfunction. In the diabetes programs at Children's Hospital, the fellow works with multidisciplinary teams that include nurse educators, nutritionists, and social workers to treat both type 1 and type 2 diabetes. The end of each clinic session is highlighted by a lively post-clinic conference at which all fellows, house staff, students, and faculty review the cases of instructive patients seen in clinic that day. Fellows develop their own panel of patients whom they follow longitudinally, working closely with members of the Endocrinology Division faculty and allowing them to determine the course of treatment and monitor outcomes.
During the 4 months of the urgent care/ educational outpatient rotations at Children’s Hospital, the fellow sees predominantly new patients in need of urgent consultations, interacts with primary care physicians with regard to possible referrals, attends 1-2 endocrine subspecialty clinics per week, and has approximately 5-10 hours/week available for scholarly activities. Fellows are encouraged to carry out an independent clinical research project during this time.
First year fellows take weeknight call from home once weekly for the inpatient Endocrinology and Diabetes services. Weekend call is divided equally among fellows of all three years. Weekend inpatient call occurs every 9th weekend (on average) and includes daytime rounding in the hospital and overnight call from home (Fri-Sun). In addition, each fellow takes diabetes outpatient call from home (Sat/Sun mornings 8a-12p) every 9th weekend to allow for more efficient inpatient rounding.
During the first year, each fellow prepares and conducts approximately 10 clinical conferences attended by endocrinologists at Children's Hospital, Joslin Diabetes Center (JDC), BWH, BIDMC, and the other Harvard-affiliated teaching hospitals in the Harvard Medical School (HMS) area. These conferences give the fellow the opportunity to investigate clinical topics in depth and to engage a group of senior endocrinologists in discussion (see schedule below).
The Second and Third Years
Under the supervision of a faculty preceptor selected during the first year, the fellow undertakes a comprehensive investigation of one area of basic or clinical research. In both the second and third years, each fellow also continues longitudinal clinics for one half-day per week in general endocrinology and diabetes at Children's Hospital. All second or third year fellows spend one week at a summer camp for children with diabetes, where practical issues in diabetes outpatient management are emphasized under the guidance of attending staff.
In the second and third years, each fellow takes weeknight call from home for the inpatient Endocrinology and Diabetes services once every 6 weeks. Weekend calls are divided evenly among fellows of all three years.
The fellowship has an extensive curriculum that combines lectures, journal clubs, seminars and case conferences to provide a variety of educational activities, including the opportunity to teach and to learn from multi-disciplinary teams.
- Endocrine Summer Seminars (common problems in endocrinology)
- Endocrine Clinical Case Conference (led by first year fellows)
- Endocrinology Division Seminar Series
- Boston Children’s Hospital/Brigham & Women’s Hospital Endocrine Grand Rounds
- Department of Medicine Grand Rounds
- Endocrine Fellow Lecture Series at BIDMC (clinical topics in adult and pediatric endocrinology)
- BIDMC Endocrine Grand Rounds
- Clinical Diabetes and Metabolism Conference at Joslin Diabetes Center
- Diabetes/Metabolism Research Seminar Series at Joslin Diabetes Center
- Fundamentals of Endocrinology (fellows-only: endocrine physiology/pathophysiology/Board review)
- Pediatric Thyroid Clinical Conference
- Reproductive Endocrinology Joint Conference with Adolescent Medicine Division
- Mineral Monday (clinical cases on mineral and bone metabolism)
- Diabetes High Risk Forum
- Endocrinology Clinical Research Conference
- Endocrinology Fellow Journal Club
- Lightning Journal Rounds (brief review of the month’s issue of JCEM)
- Endocrine Basic Research Meeting
- Longwood Area Thyroid Clinical Conference
- Tea with Fellows and Division Chief
- General Surgery/Endocrinology Joint Case Conference
- Neurosurgery/Endocrinology Joint Case Conference
- Urology/Endocrinology Joint Case Conference
Diverse research opportunities exist within the Children's Hospital Division of Endocrinology. In addition, many of our fellows undertake their 2nd/3rd year fellowship research at JDC, BWH, BIDMC, Massachusetts General Hospital, Massachusetts Institute of Technology, or Harvard Medical School.
A wide variety of projects are available at the level of population sciences, patient-oriented research, isolated genes, cells, and intact organisms that include transgenic, knockout and knockin mouse models of human diseases. Selected fellows may obtain a MPH from the Harvard Chan School of Public Health or a Master of Medical Sciences from Harvard Medical School.
Bioinformatics, Medical Informatics (Preceptors: Isaac Kohane MD PhD, Kenneth Mandl MD MPH) Department of Biomedical Informatics, HMS, and Computational Health Informatics Program (CHIP), BCH. Multiple projects in biomedical sciences, health care delivery, natural language processing of EMR data, and population health, involving high-dimensional modeling and understanding of patients from the molecular to the population levels.
Calcium, Mineral, and Bone Homeostasis (Preceptors: Christina Jacobsen MD PhD, Nina Ma, MD, Melissa Putman MD) Mechanisms and treatment of metabolic bone diseases including osteogenesis imperfecta and other genetic disorders, CF-related osteopenia, vitamin D disorders, immobility, and others.
Carbohydrate Metabolism and Diabetes Clinical Research (Preceptors: Joseph Wolfsdorf MB BCh, Katharine Garvey MD MPH, Michael Agus MD, Amy Fleischman MD MMSc, Erinn Rhodes MD MPH, Maryanne Quinn MD MPH, Garry Steil PhD) Transition to adult care in T1D care; integration of exercise with other diabetes treatment technologies; algorithms for open/closed loop management of T1D; optimal treatment for diabetic ketoacidosis.
Endocrine Disorders in Critical Care (Preceptor: Michael Agus MD) Hypoglycemia in critically ill children; role of glucocorticoid treatment in critically ill children.
Diabetes and Obesity Basic Research (Preceptors: Morris White PhD, Umut Ozcan MD, Sudha Biddinger MD PhD, Joseph Majzoub MD, Nicholas Stylopoulos MD, Nada Kalaany PhD, Sang Park PhD, Ji Miao PhD) Role of IRS proteins in insulin signaling, pancreatic beta cell biology, and etiology of type 1 and type 2 diabetes; role of endoplasmic reticulum stress in insulin action, beta cell function, and energy regulation; role of insulin resistance in the metabolic syndrome; regulation of appetite and energy expenditure; mechanism of action of bariatric surgery; role of obesity in cancer pathogenesis.
Gender/Transgender Research (Preceptors Yee-Ming Chan MD PhD, Jeremi Carswell MD, Norman Spack MD, Amy Tishelman PhD) Genetics and diagnosis of delayed puberty and disorders of sex development (DSD); outcomes and treatment of DSD; diagnosis, treatment, and outcomes of transgender patients, including with hormone-blockers in adolescence.
Genomic Research in Endocrinology (Preceptors: Joel Hirschhorn MD PhD, Ingrid Holm MD MPH) Genetics of obesity, puberty and growth disorders; genetics of T1D, T2D, and their complications; new methods for genomic data analysis; role of Next Gen sequencing in diagnosis of neonatal diseases; disclosure of Next Gen sequencing results to patients.
Mammalian Stress Response (Preceptor: Joseph Majzoub MD) Regulation of the hypothalamic-pituitary-adrenal axis by corticotropin-releasing hormone (CRH) and vasopressin; role of CRH in fetal development and timing of parturition; physiology/pathophysiology of adrenarche .
Obesity Clinical Research (Preceptors: David Ludwig MD PhD, Cara Ebbeling PhD, Belinda Lennerz MD PhD, Amy Fleischman MD MMSc) Role of dietary composition in appetite and body weight regulation in humans; use of low glycemic index diets to prevent and treat obesity, cardiovascular disease and diabetes mellitus; obesity management using telemedicine.
Neuroendocrinology Research (Preceptors: Laurie Cohen MD, Diane Stafford MD) Causes and treatment of hypothalamic obesity in children with brain tumors and Prader-Willi syndrome, including uses of growth hormone.
Stem Cell Biology in Endocrinology (Preceptors: David Breault MD PhD, Diana Carlone PhD) Role of stem cells, induced pluripotential cells, gut-derived progenitor cells, and organoids in endocrine physiology and therapeutics, including in pancreatic islets and the adrenal.
Thyroid Pathophysiology in Children (Preceptors: Ari Wassner MD, Jessica Smith MD) Diagnosis and management of thyroid nodules and cancer in children and adolescents; management of Graves’ disease; pathology and treatment of autoimmune thyroiditis, congenital hypothyroidism and iodine-induced thyroid diseases.
For further information contact:
Diane Stafford, M.D.
Director, Training Program in Pediatric Endocrinology at Boston Children's Hospital, Boston Children's Hospital, 300 Longwood Avenue, Boston, MA 02115
Tel 617-355-5066 Fax 617-730-0194 Email: firstname.lastname@example.org
For information about our program in PDF format, please click here.
We are grateful to have been ranked #1 on U.S. News & World Report's list of the best children's hospitals in the nation for the third year in a row, an honor we could not have achieved without the patients and families who inspire us to do our very best for them. Thanks to you, Boston Children's is a place where we can write the greatest children's stories ever told.”