Below is a sampling of clinical trials now open for recruitment. For a longer list, visit www.childrenshospital.org/research/clinical/Search.cfm. Families can learn more about clinical trial participation by visiting the interactive Parent's Guide to Medical Research at www.bostonchild.vitalconsent.com
Blood test for endometriosis
Endometriosis occurs in both women and adolescent girls and is currently diagnosed only by laparoscopy. A trial at Children's Hospital Boston will evaluate a new blood test for diagnosing this painful and fertility-threatening condition, based on detection of certain antibodies. Marc Laufer, MD, chief of Gynecology, will conduct blood tests in 30 girls, age 15 to 18, who are undergoing laparoscopy to evaluate pelvic pain. If the blood test proves as accurate as hoped, it may allow some girls to avoid surgery. For more information, email Dr. Laufer at marc.laufer@childrens.harvard.edu.
When to recommend surgery for crossed eyes
Strabismus surgery for children with esotropia (crossed eyes) has traditionally been delayed until the angle of the eyes' misalignment is stabilized, but some studies document better visual outcomes with very early surgery. Children's is taking part in a multicenter esotropia treatment study designed to identify the best time to intervene. Children under age 5 (including infants) with esotropia for less than six months and no history of prematurity or developmental delays are eligible. For more information, email Linda Dagi, MD, at linda.dagi@childrens.harvard.edu.
