|Cara Ebbeling, PhD
The purpose of this research study is to compare two different diets for treating Polycystic
Ovary Syndrome (PCOS). Participants will be randomized to either a low-fat diet (consistent with the Diabetes Prevention Program) or a low-glycemic diet. The study lasts six months. Benefits include a weight loss program, cooking workshops with a chef, and individual nutrition education and dietary counseling with a registered dietitian. Participants receive a $100 American Express gift card at the completion of the study.
Eligibility: Overweight girls ages 13 to 17 who have PCOS may be eligible.
Contact: Julia Wong, PhD, at 617-355-2500 or email@example.com.
The purpose of this study is to look at the effects of a short-term cognitive-behavioral
therapy, which teaches children and adolescents more effective ways to think
and act in order to cope with their illness. During this study, a brief questionnaire
will be given and a baseline assessment interview conducted. If the child meets
criteria, there will be between eight and 12 one-hour "coping skills coaching" sessions
over a three month period. There will also be four "booster" sessions
following completion of the program. There will be two-hour assessments three,
nine, 15 and 18 months after the program.
Eligibility: Children and adolescents with irritable
bowel disease (IBD) between 9 and 17 may be eligible.
Contact: Peter Ducharme at 617-355-2353 or
The purpose of this study is to gather detailed historical and physical examination data on a large cohort of females with Rett
syndrome and establish a phenotype-genotype correlation over a broad spectrum of phenotypes. No treatment is involved or will be recommended. After the initial assessment, semi-annual or annual visits will be required.
Eligibility: Participants must meet all established clinical
criteria for classic or variant Rett syndrome or individuals with MECP2 mutations
who do not meet the clinical criteria. All ages will be eligible.
Contact: Kate Barnes at 617-355-5230 or