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Although there have been many studies of spinal fusion to treat scoliosis, there has yet to be a comprehensive multicenter prospective study that compares the functional and surgical outcomes of different surgical techniques. Participants will be asked to fill out questionnaires and take part in regular standard care visits.
Eligibility: Patients will be asked to enroll in this study based on a diagnosis of thoracic, thoracolumbar and/or lumbar pediatric and/or adolescent idiopathic scoliosis. They must be between 8 and 18 years old at the radiographic diagnosis of operative idiopathic scoliosis. Patients must have surgery before the age of 21.
Contact: Ashley Goldthwait at 617-355-7703 or
ashley.goldthwait@childrens.harvard.edu
The purpose of this study is to compare the use of different imaging methods—MRI and SPECT—to diagnose and monitor spondylolysis (a stress fracture in the lower back). Participants will receive a physical exam, a SPECT bone scan and MRIs at the initial visit. They will be asked to return after four and six months to repeat the physical exam. Participants will be given $50 as reimbursement for each MRI after completing the study.
Eligibility: Children and young adults between the ages of 12 and 18 with extension-based back pain may be eligible.
Contact: Christine Curtis at 617-355-8669 or christine.curtis@childrens.harvard.edu
This study is designed to investigate a theory as to why food allergy diagnoses, particularly peanut allergy, have become an increasingly common occurrence in the past 10 years. The study seeks to examine a link between IVF and increased risk of childhood peanut allergy. Participants will be asked to complete a questionnaire about personal, medical, reproductive and family history as they may relate to the child's allergy diagnosis. The child's medical record will be reviewed and test results that indicate allergy levels will be collected. Participants will receive a gift certificate or a voucher for parking.
Eligibility: Parents of children who have had at least one food allergy to milk, egg or other foods except peanut are eligible.
Contact: Irene Borras at 617-6127 or studyinfo-dl@childrens.harvard.edu
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