Low vitamin D levels are common among teenagers andİmay contribute to the development of osteoporosis, diabetes and cancer. We want to see if healthy teenagers taking an adult dose of vitamin D haveİsafe, higherİblood levels of Vitamin Dİthan thoseİtaking children’s doses. During the 12-week study, blood will be drawn and participants will be randomized to one of two daily vitamin D doses. Participants will receive $10 for the screening visit and a $50 Visa card for completing the two study visits.
Eligibility: Healthy adolescents between 11 and 18 who do not take medications that could affect the study and are able to swallow pills may be eligible.
Contact: Allison Kutner at 617-355-2212 or firstname.lastname@example.org
This study will evaluate the usefulness of adenotonsillectomy versus medical therapy in children with mild obstructive sleep apnea (OSA). Neurocognitive testing and a sleep study will be performed, and participants will receive $450 upon completion of the study.
Eligibility: Children between 5 and 9.9 years old with no significant medical problems who are candidates for adenotonsillectomy with mild OSA may be eligible.
Contact: Felix Vincent at 617-355-5309 or email@example.com
Fanconi anemia (FA) is characterized by progressive bone marrow failure, chromosomal fragility, birth defects and an increased risk of leukemia and solid tumors. Though stem cell transplantation is viable, it’s complicated by increased treatment-related toxicities and graft-vs.-host disease. This study will examine engraftment, toxicity, graft-vs.-host disease and disease-free survival following a novel cytoreductive transplant regimen that also avoids total body irradiation.
Eligibility: Patients with FA and one hematologic diagnosis (severe aplastic anemia, myelodysplastic syndrome or acute myelogenous leukemia) may be eligible.
Contact: David Williams, MD, at 617-919-2697 or firstname.lastname@example.org
More trials: childrenshospital.org/clinicaltrials