Research

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Susanna Huh, MD, MPH

Department:
Medicine Research
Division
Gastroenterology, Hepatology and Nutrition Research
Hospital Title:
Director, Growth and Nutrition Program
Academic Title:
Assistant Professor of Pediatrics, Harvard Medical School
Research Focus Area:
NutritionObesity prevention
Contact:
617-355-7713
Contact Via Email
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Research Overview

The goal of my research is to identify modifiable dietary and behavioral risk factors in early life associated with childhood health outcomes, particularly body composition and cardiometabolic risk. Since 2005, I have been a co-investigator for Project Viva, an NIH-funded pre-birth longitudinal cohort of mother-child dyads that provides the main database for my research.  Within Project Viva, I led studies showing that early solid food introduction was associated with higher risk of obesity in predominantly formula-fed infants, and that cesarean delivery was associated with child obesity.  My current clinical research focuses on risk factors and management of feeding difficulties and poor weight gain; malnutrition screening in pediatric inpatients; and the effects of modified fat breast milk on nutritional status of infants with congenital heart disease. 

About Susanna Huh

Dr. Huh is board-certified in both pediatric gastroenterology and nutrition. She obtained her medical degree at the University of Western Ontario in Canada. She completed a clinical and research fellowship in the Harvard Medical School Program in Pediatric Gastroenterology and Nutrition, and obtained her Master of Public Health degree at the Harvard School of Public Health.  Dr. Huh is Associate Director for the Center for Nutrition at Boston Children’s Hospital and an Assistant Professor of Pediatrics, Harvard Medical School.  In addition to practicing general pediatric gastroenterology, she directs the Growth and Nutrition Program, a multidisciplinary program offering diagnosis and treatment for children with failure-to-thrive and feeding difficulties.  Dr. Huh has served on the Training and Nutrition Committees for the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN).  She has taught gastroenterology, nutrition, clinical epidemiology, and critical interpretation of medical literature to medical students, pediatric residents, and fellows.  She directs a 4th-year nutrition elective for medical students, and directs nutrition education for pediatric residents and fellows at Boston Children’s Hospital.  She is a member of the Medical Advisory Board for the Mothers’ Milk Bank of New England.

Key Publications

Huh SY, Rifas-Shiman SL, Kleinman KP, Rich-Edwards JW, Lipshultz SE, Gillman MW.  Maternal protein intake is not associated with infant blood pressure.  International Journal of Epidemiology 2005; 34(2):378-84. 

Huh SY, Gordon CM. Vitamin D deficiency in children and adolescents: epidemiology, impact and treatment.  Rev Endo Metab Dis 2008; Jun;9(2):161-170.

Huh SY, Feldman HA, Cox, J, Gordon CM. Prevalence of transient hyperphosphatasemia among healthy infants and toddlers. Pediatrics 2009; 124(2):703-9.

Huh SY, Rifas-Shiman S, Rich-Edwards JW, Taveras EM, Gillman MW. Prospective association between milk intake and adiposity in preschool age children. J Am Diet Assoc 2010; 110(4):563-70.

Huh SY,* Rifas-Shiman SL,* Oken E, Taveras EM, Gillman MW. Timing of solid food introduction and risk of obesity in preschool age children.  Pediatrics 2011; 127(3):e544-51. *These authors contributed equally to this work and hold shared first authorship.  

Gordon C, Gordon L, Snyder BD, Nazarian A, Quinn N, Huh S, Giobbie-Hurder A, Neuberg D, Cleveland R, Kleinman M, Kieran M.  Hutchinson-Gilford Progeria is a Skeletal Dysplasia. Journal of Bone and Mineral Research 2011; 26(7):1670-9. 

Huh SY, Rifas-Shiman SL, Zera C, Oken E, Rich-Edwards J, Weiss ST, Gillman MW. Delivery by caesarean section and risk of obesity in preschool age children.  Arch Dis Child 2012;97(7):610-6.

Topor LS, Borus JS, Aspinwall S, Gilbert CL, Gordon CM, Huh SY. Fractures among inpatients in a pediatric hospital.  Hosp Pediatr 2015: in press.

Publications

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  1. Gordon LB, Kleinman ME, Massaro J, D'Agostino RB, Shappell H, Gerhard-Herman M, Smoot LB, Gordon CM, Cleveland RH, Nazarian A, Snyder BD, Ullrich NJ, Silvera VM, Liang MG, Quinn N, Miller DT, Huh SY, Dowton AA, Littlefield K, Greer MM, Kieran MW. Clinical Trial of the Protein Farnesylation Inhibitors Lonafarnib, Pravastatin, and Zoledronic Acid in Children With Hutchinson-Gilford Progeria Syndrome. Circulation. 2016 Jul 12; 134(2):114-25.
  2. Topor LS, Borus JS, Aspinwall S, Gilbert CL, Gordon CM, Huh SY. Fractures Among Inpatients in a Pediatric Hospital. Hosp Pediatr. 2016 Mar; 6(3):143-50.
  3. Huh SY, Sullivan NR, Huntington N. Psychological and Psychosocial Impairment in Preschoolers With Selective Eating: Concerns Regarding Methods and Data Interpretation. Pediatrics. 2016 Jan; 137(1).
  4. Oken E, Baccarelli AA, Gold DR, Kleinman KP, Litonjua AA, De Meo D, Rich-Edwards JW, Rifas-Shiman SL, Sagiv S, Taveras EM, Weiss ST, Belfort MB, Burris HH, Camargo CA, Huh SY, Mantzoros C, Parker MG, Gillman MW. Cohort profile: project viva. Int J Epidemiol. 2015 Feb; 44(1):37-48.
  5. Burris HH, Rifas-Shiman SL, Huh SY, Kleinman K, Litonjua AA, Oken E, Rich-Edwards JW, Camargo CA, Gillman MW. Vitamin D status and hypertensive disorders in pregnancy. Ann Epidemiol. 2014 May; 24(5):399-403.e1.
  6. Gordon LB, Kleinman ME, Miller DT, Neuberg DS, Giobbie-Hurder A, Gerhard-Herman M, Smoot LB, Gordon CM, Cleveland R, Snyder BD, Fligor B, Bishop WR, Statkevich P, Regen A, Sonis A, Riley S, Ploski C, Correia A, Quinn N, Ullrich NJ, Nazarian A, Liang MG, Huh SY, Schwartzman A, Kieran MW. Clinical trial of a farnesyltransferase inhibitor in children with Hutchinson-Gilford progeria syndrome. Proc Natl Acad Sci U S A. 2012 Oct 09; 109(41):16666-71.
  7. Huh SY, Gordon CM. Fractures in hospitalized children. Metabolism. 2013 Mar; 62(3):315-25.
  8. Burris HH, Rifas-Shiman SL, Camargo CA, Litonjua AA, Huh SY, Rich-Edwards JW, Gillman MW. Plasma 25-hydroxyvitamin D during pregnancy and small-for-gestational age in black and white infants. Ann Epidemiol. 2012 Aug; 22(8):581-6.
  9. Burris HH, Rifas-Shiman SL, Kleinman K, Litonjua AA, Huh SY, Rich-Edwards JW, Camargo CA, Gillman MW. Vitamin D deficiency in pregnancy and gestational diabetes mellitus. Am J Obstet Gynecol. 2012 Sep; 207(3):182.e1-8.
  10. Huh SY, Rifas-Shiman SL, Zera CA, Edwards JW, Oken E, Weiss ST, Gillman MW. Delivery by caesarean section and risk of obesity in preschool age children: a prospective cohort study. Arch Dis Child. 2012 Jul; 97(7):610-6.
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  12. Gordon CM, Gordon LB, Snyder BD, Nazarian A, Quinn N, Huh S, Giobbie-Hurder A, Neuberg D, Cleveland R, Kleinman M, Miller DT, Kieran MW. Hutchinson-Gilford progeria is a skeletal dysplasia. J Bone Miner Res. 2011 Jul; 26(7):1670-9.
  13. Huh SY, Rifas-Shiman SL, Taveras EM, Oken E, Gillman MW. Timing of solid food introduction and risk of obesity in preschool-aged children. Pediatrics. 2011 Mar; 127(3):e544-51.
  14. Huh SY, Rifas-Shiman SL, Rich-Edwards JW, Taveras EM, Gillman MW. Prospective association between milk intake and adiposity in preschool-aged children. J Am Diet Assoc. 2010 Apr; 110(4):563-70.
  15. Huh SY, Feldman HA, Cox JE, Gordon CM. Prevalence of transient hyperphosphatasemia among healthy infants and toddlers. Pediatrics. 2009 Aug; 124(2):703-9.
  16. Huh SY, Andrew R, Rich-Edwards JW, Kleinman KP, Seckl JR, Gillman MW. Association between umbilical cord glucocorticoids and blood pressure at age 3 years. BMC Med. 2008 Aug 28; 6:25.
  17. Huh SY, Gordon CM. Vitamin D deficiency in children and adolescents: epidemiology, impact and treatment. Rev Endocr Metab Disord. 2008 Jun; 9(2):161-70.
  18. Gillman MW, Rich-Edwards JW, Huh S, Majzoub JA, Oken E, Taveras EM, Rifas-Shiman SL. Maternal corticotropin-releasing hormone levels during pregnancy and offspring adiposity. Obesity (Silver Spring). 2006 Sep; 14(9):1647-53.
  19. Oken E, Huh SY, Taveras EM, Rich-Edwards JW, Gillman MW. Associations of maternal prenatal smoking with child adiposity and blood pressure. Obes Res. 2005 Nov; 13(11):2021-8.
  20. Huh SY, Rifas-Shiman SL, Kleinman KP, Rich-Edwards JW, Lipshultz SE, Gillman MW. Maternal protein intake is not associated with infant blood pressure. Int J Epidemiol. 2005 Apr; 34(2):378-84.
  21. Chow LH, Huh S, Jiang J, Zhong R, Pickering JG. Intimal thickening develops without humoral immunity in a mouse aortic allograft model of chronic vascular rejection. Circulation. 1996 Dec 15; 94(12):3079-82.
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