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Pierre E.  Dupont, PhD

Pierre E. Dupont
Pediatric Cardiac Bioengineering Laboratory
Cardiac Surgery Research
Hospital Title:
Staff Scientist, Cardiovascular Surgery; Chief, Pediatric Cardiac Bioengineering
Academic Title:
Visiting Professor of Surgery, Harvard Medical School
Research Focus Area:
Robotic Instruments and Imaging TechnologyCongenital Heart DefectsFetal and Pediatric Heart

Lab Web Site:  Pediatric Cardiac Bioengineering Lab

Research Overview

Pierre Dupont's group develops new technologies for performing image-guided minimally invasive surgery. The research is interdisciplinary, drawing from many branches of engineering. Specific topics of interest include the design and control of novel medical robots and instruments, modeling tool-tissue interaction, the development of multi-probe or multi-modal imaging techniques for surgical guidance; and the teleoperation or automation of instrument motion. The goal of his research is to create technology that enables minimally invasive interventions for procedures that are currently performed as open surgery. This approach minimizes the collateral trauma and risks of surgical interventions and, consequently, facilitates earlier intervention in the disease process. 

About Pierre E. Dupont, PhD

Pierre Dupont received a PhD in mechanical engineering from Rensselaer Polytechnic Institute. He was a postdoctoral fellow in the School of Engineering and Applied Sciences at Harvard University. He subsequently joined the College of Engineering at Boston University where he was a professor in the Departments of Mechanical Engineering and Biomedical Engineering. He recently moved his group from BU to Boston Children's Hospital.


Publications powered by Harvard Catalyst Profiles
  1. Manjila S, Mencattelli M, Rosa B, Price K, Fagogenis G, Dupont PE. A multiport MR-compatible neuroendoscope: spanning the gap between rigid and flexible scopes. Neurosurg Focus. 2016 Sep; 41(3):E13.
  2. Ha J, Park FC, Dupont PE. Elastic Stability of Concentric Tube Robots Subject to External Loads. IEEE Trans Biomed Eng. 2016 Jun; 63(6):1116-28.
  3. Iacovacci V, Lucarini G, Ricotti L, Dario P, Dupont PE, Menciassi A. Untethered magnetic millirobot for targeted drug delivery. Biomed Microdevices. 2015; 17(3):9962.
  4. Codd PJ, Veaceslav A, Gosline AH, Dupont PE. Novel pressure-sensing skin for detecting impending tissue damage during neuroendoscopy. J Neurosurg Pediatr. 2014 Jan; 13(1):114-21.
  5. Vasilyev NV, Gosline AH, Butler E, Lang N, Codd PJ, Yamauchi H, Feins EN, Folk CR, Cohen AL, Chen R, Zurakowski D, del Nido PJ, Dupont PE. Percutaneous steerable robotic tool delivery platform and metal microelectromechanical systems device for tissue manipulation and approximation: closure of patent foramen ovale in an animal model. Circ Cardiovasc Interv. 2013 Aug; 6(4):468-75.
  6. Vasilyev NV, Dupont PE, del Nido PJ. Robotics and imaging in congenital heart surgery. Future Cardiol. 2012 Mar; 8(2):285-96.
  7. Bergeles C, Qin L, Vartholomeos P, Dupont PE. Tracking and position control of an MRI-powered needle-insertion robot. Conf Proc IEEE Eng Med Biol Soc. 2012; 2012:928-31.
  8. Stoll J, Ren H, Dupont PE. Passive markers for tracking surgical instruments in real-time 3-D ultrasound imaging. IEEE Trans Med Imaging. 2012 Mar; 31(3):563-75.
  9. Laing G, Dupont PE. Beating-heart mitral valve chordal replacement. Conf Proc IEEE Eng Med Biol Soc. 2011; 2011:2476-9.
  10. Ren H, Dupont PE. Tubular structure enhancement for surgical instrument detection in 3D ultrasound. Conf Proc IEEE Eng Med Biol Soc. 2011; 2011:7203-6.
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  12. Mahvash M, Dupont PE. Mechanics of dynamic needle insertion into a biological material. IEEE Trans Biomed Eng. 2010 Apr; 57(4):934-43.
  13. Perrin DP, Vasilyev NV, Novotny P, Stoll J, Howe RD, Dupont PE, Salgo IS, del Nido PJ. Image guided surgical interventions. Curr Probl Surg. 2009 Sep; 46(9):730-66.
  14. Huang J, Triedman JK, Vasilyev NV, Suematsu Y, Cleveland RO, Dupont PE. Imaging artifacts of medical instruments in ultrasound-guided interventions. J Ultrasound Med. 2007 Oct; 26(10):1303-22.
  15. Novotny PM, Stoll JA, Vasilyev NV, del Nido PJ, Dupont PE, Zickler TE, Howe RD. GPU based real-time instrument tracking with three-dimensional ultrasound. Med Image Anal. 2007 Oct; 11(5):458-64.
  16. Novotny PM, Jacobsen SK, Vasilyev NV, Kettler DT, Salgo IS, Dupont PE, Del Nido PJ, Howe RD. 3D ultrasound in robotic surgery: performance evaluation with stereo displays. Int J Med Robot. 2006 Sep; 2(3):279-85.
  17. Huang J, Dupont PE, Undurti A, Triedman JK, Cleveland RO. Producing diffuse ultrasound reflections from medical instruments using a quadratic residue diffuser. Ultrasound Med Biol. 2006 May; 32(5):721-7.
  18. Novotny PM, Kettler DT, Jordan P, Dupont PE, del Nido PJ, Howe RD. Stereo display of 3D ultrasound images for surgical robot guidance. Conf Proc IEEE Eng Med Biol Soc. 2006; 1:1509-12.
  19. Novotny PM, Stoll JA, Vasilyev NV, del Nido PJ, Dupont PE, Howe RD. GPU based real-time instrument tracking with three dimensional ultrasound. Med Image Comput Comput Assist Interv. 2006; 9(Pt 1):58-65.
  20. Suematsu Y, Martinez JF, Wolf BK, Marx GR, Stoll JA, DuPont PE, Howe RD, Triedman JK, del Nido PJ. Three-dimensional echo-guided beating heart surgery without cardiopulmonary bypass: atrial septal defect closure in a swine model. J Thorac Cardiovasc Surg. 2005 Nov; 130(5):1348-57.
  21. Stoll J, Dupont P. Passive markers for ultrasound tracking of surgical instruments. Med Image Comput Comput Assist Interv. 2005; 8(Pt 2):41-8.
  22. Suematsu Y, Marx GR, Stoll JA, DuPont PE, Cleveland RO, Howe RD, Triedman JK, Mihaljevic T, Mora BN, Savord BJ, Salgo IS, del Nido PJ. Three-dimensional echocardiography-guided beating-heart surgery without cardiopulmonary bypass: a feasibility study. J Thorac Cardiovasc Surg. 2004 Oct; 128(4):579-87.
  23. Cannon JW, Howe RD, Dupont PE, Triedman JK, Marx GR, del Nido PJ. Application of robotics in congenital cardiac surgery. Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu. 2003; 6:72-83.
  24. Cannon JW, Stoll JA, Salgo IS, Knowles HB, Howe RD, Dupont PE, Marx GR, del Nido PJ. Real-time three-dimensional ultrasound for guiding surgical tasks. Comput Aided Surg. 2003; 8(2):82-90.
  25. De Man B, Nuyts J, Dupont P, Marchal G, Suetens P. An iterative maximum-likelihood polychromatic algorithm for CT. IEEE Trans Med Imaging. 2001 Oct; 20(10):999-1008.
  26. Nuyts J, Michel C, Dupont P. Maximum-likelihood expectation-maximization reconstruction of sinograms with arbitrary noise distribution using NEC-transformations. IEEE Trans Med Imaging. 2001 May; 20(5):365-75.
  27. Nuyts J, Dupont P, Stroobants S, Benninck R, Mortelmans L, Suetens P. Simultaneous maximum a posteriori reconstruction of attenuation and activity distributions from emission sinograms. IEEE Trans Med Imaging. 1999 May; 18(5):393-403.
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