Research

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Patricia R. Bachiller, MD

Patricia Bachiller MD
Department:
Department of Anesthesiology, Perioperative and Pain Medicine Research
Research Focus Area:
Bronchopulmonary dysplasiaNeonatal chronic lung disease

Research Overview

I am interested in understanding and ameliorating the arrest of alveolar and microvascular development that occurs in the premature neonatal lung affected by bronchopulmonary dysplasia.

Publications

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  1. Bachiller PR, McDonough JM, Feldman JM. Do new anesthesia ventilators deliver small tidal volumes accurately during volume-controlled ventilation? Anesth Analg. 2008 May; 106(5):1392-400, table of contents.
  2. Bachiller PR, McDonough JM, Feldman JM. Can Volume-Controlled Ventilation Re-emerge in Pediatric Anesthesia?. Society for Pediatric Anesthesia/American Academy of Pediatrics Winter Meeting 2007. 2007; (P19).
  3. Patricia R. Bachiller and Jean Kwo. Gastrointestinal Disease. Critical Care Handbook of the Massachusetts General Hospital, editors: Bigatello, et al. 2005; 464-487.
  4. Patricia R. Bachiller. Studying the Interaction Between Gelsolin and Phosphatidylinositol 4,5-bisphosphate: Fluorescence Techniques In Vitro (M.D. Thesis). 2001.
  5. Tuominen EK, Holopainen JM, Chen J, Prestwich GD, Bachiller PR, Kinnunen PK, Janmey PA. Fluorescent phosphoinositide derivatives reveal specific binding of gelsolin and other actin regulatory proteins to mixed lipid bilayers. Eur J Biochem. 1999 Jul; 263(1):85-92.
  6. Bachiller PR, Ahn S, and Warren WS. Detection of Intermolecular Heteronuclear Multiple-Quantum Coherences in Solution NMR. Journal of Magnetic Resonance, Series A. 1996; 122(1):94-99.
  7. Patricia R. Bachiller. Observation of Intermolecular Heteronuclear Dipolar Couplings in Solution NMR (Undergraduate Thesis). 1996.
  8. Bachiller PR, Nakanishi H, Roberts JD. Transforming growth factor-beta modulates the expression of nitric oxide signaling enzymes in the injured developing lung and in vascular smooth muscle cells. Am J Physiol Lung Cell Mol Physiol. 2010 Mar; 298(3):L324-34.
  9. Bachiller PR, Cornog KH, Kato R, Buys ES, Roberts JD. Soluble guanylate cyclase modulates alveolarization in the newborn lung. Am J Physiol Lung Cell Mol Physiol. 2013 Oct 15; 305(8):L569-81.
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