Research

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Leslie Kalish, ScD

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Research Center:
Orthopedic Clinical Effectiveness Research Center
Hospital Title:
Principal Biostistician
Academic Title:
Associate Professor of Pediatrics, Harvard Medical School
Research Focus Area:
Biostatistical Support and Collaboration
Contact:
(857) 218-4723
Contact Via Email
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Research Overview

Dr. Kalish's primary area of collaboration is with the Department of Orthopedic Surgery. Over his career, other areas of collaboration have included HIV and other infectious diseases, transfusion medicine, oncology, alternative medicine, and several pediatric sub-specialties. He has also conducted methodological research in statistical design and analysis, focusing on applying optimal statistical design methodology to treatment allocation procedures for clinical trials and to the design of observational epidemiologic studies.

About the Researcher

Dr. Kalish is a Principal Biostatistician in the Biostatistics and Research Design core of the Institutional Centers for Clinical and Translational Research. He holds a Harvard Medical School appointment as Associate Professor of Pediatrics. The focus of Dr. Kalish's professional career has been bringing biostatistical expertise to biomedical investigations through the design, coordination, and analysis of clinical trials, epidemiologic studies, and other studies. His contributions toward these activities have included methodological research in biostatistics, epidemiology and clinical trial design; scientific leadership and collaboration; coordination of the operations, data management and statistical analyses of multi center research studies; and training and supervision in these areas.

Publications

Publications powered by Harvard Catalyst Profiles
  1. Ting BL, Kalish LA, Waters PM, Bae DS. Reducing Cost and Radiation Exposure During the Treatment of Pediatric Greenstick Fractures of the Forearm. J Pediatr Orthop. 2016 Dec; 36(8):816-820.
  2. Murray MM, Flutie BM, Kalish LA, Ecklund K, Fleming BC, Proffen BL, Micheli LJ. The Bridge-Enhanced Anterior Cruciate Ligament Repair (BEAR) Procedure: An Early Feasibility Cohort Study. Orthop J Sports Med. 2016 Nov; 4(11):2325967116672176.
  3. Nasreddine AY, Connell PL, Kalish LA, Nelson S, Iversen MD, Anderson AF, Kocher MS. The Pediatric International Knee Documentation Committee (Pedi-IKDC) Subjective Knee Evaluation Form: Normative Data. Am J Sports Med. 2017 03; 45(3):527-534.
  4. Farr S, Kalish LA, Bae DS, Waters PM. Radiographic Criteria for Undergoing an Ulnar Shortening Osteotomy in Madelung Deformity: A Long-term Experience From a Single Institution. J Pediatr Orthop. 2016 Apr-May; 36(3):310-5.
  5. Kramer DE, Kalish LA, Abola MV, Kramer EM, Yen YM, Kocher MS, Micheli LJ. The effects of medial synovial plica excision with and without lateral retinacular release on adolescents with anterior knee pain. J Child Orthop. 2016 Apr; 10(2):155-62.
  6. Bulat E, Bixby SD, Siversson C, Kalish LA, Warfield SK, Kim YJ. Planar dGEMRIC Maps May Aid Imaging Assessment of Cartilage Damage in Femoroacetabular Impingement. Clin Orthop Relat Res. 2016 Feb; 474(2):467-78.
  7. Hingsammer AM, Stelzeneder D, Kalish LA, Millis MB, Kim YJ. Prognostic factors for mid-term symptom relief after open surgical correction for femoroacetabular impingement. Hip Int. 2015 Sep-Oct; 25(5):406-12.
  8. Hingsammer AM, Kalish LA, Stelzeneder D, Bixby S, Mamisch TC, Connell P, Millis MB, Kim YJ. Does periacetabular osteotomy for hip dysplasia modulate cartilage biochemistry? J Bone Joint Surg Am. 2015 Apr 01; 97(7):544-50.
  9. Mahan ST, Kalish LA, Connell PL, Harris M, Abdul-Rahim Z, Waters P. PedsQL correlates to PODCI in pediatric orthopaedic outpatient clinic. J Pediatr Orthop. 2014 Sep; 34(6):e22-6.
  10. Hingsammer AM, Lee CB, LaReau J, Kalish LA, Kim YJ. Is acetabular osteoplasty always required in mixed impingement? Eur J Orthop Surg Traumatol. 2015 Feb; 25(2):331-8.
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  12. Shore BJ, Hutchinson S, Harris M, Bae DS, Kalish LA, Maxwell W, Waters P. Epidemiology and prevention of cast saw injuries: results of a quality improvement program at a single institution. J Bone Joint Surg Am. 2014 Feb 19; 96(4):e31.
  13. Montgomery RA, Hresko MT, Kalish LA, Gold M, Li Y, Haus B, Glotzbecker M, Berthonnaud E. Spondylolisthesis: Intra-rater and Inter-rater Reliabilities of Radiographic Sagittal Spinopelvic Parameters Using Standard Picture Archiving and Communication System Measurement Tools. Spine Deform. 2013 Nov; 1(6):412-418.
  14. Zimmerman RM, Kalish LA, Hresko MT, Waters PM, Bae DS. Surgical management of pediatric radial neck fractures. J Bone Joint Surg Am. 2013 Oct 16; 95(20):1825-32.
  15. Glotzbecker MP, Estroff JA, Curtis TA, Kalish LA, Spencer SA, Parad RB, Kasser JR, Mahan ST. Prospective evaluation of a prenatal sonographic clubfoot classification system. Fetal Diagn Ther. 2013; 34(4):236-40.
  16. Guinan EC, Palmer CD, Mancuso CJ, Brennan L, Stoler-Barak L, Kalish LA, Suter EE, Gallington LC, Huhtelin DP, Mansilla M, Schumann RR, Murray JC, Weiss J, Levy O. Identification of single nucleotide polymorphisms in hematopoietic cell transplant patients affecting early recognition of, and response to, endotoxin. Innate Immun. 2014 Oct; 20(7):697-711.
  17. Bae DS, Shah AS, Kalish LA, Kwon JY, Waters PM. Shoulder motion, strength, and functional outcomes in children with established malunion of the clavicle. J Pediatr Orthop. 2013 Jul-Aug; 33(5):544-50.
  18. Lee CB, Kalish LA, Millis MB, Kim YJ. Predictors of blood loss and haematocrit after periacetabular osteotomy. Hip Int. 2013 Nov-Dec; 23 Suppl 9:S8-13.
  19. Levesque BM, Kalish LA, Winston AB, Parad RB, Hernandez-Diaz S, Phillips M, Zolit A, Morey J, Gupta M, Mammoto A, Ingber DE, Van Marter LJ. Low urine vascular endothelial growth factor levels are associated with mechanical ventilation, bronchopulmonary dysplasia and retinopathy of prematurity. Neonatology. 2013; 104(1):56-64.
  20. Chung S, Mario Christoudias C, Darrell T, Ziniel SI, Kalish LA. A novel image-based tool to reunite children with their families after disasters. Acad Emerg Med. 2012 Nov; 19(11):1227-34.
  21. Hingsammer A, Chan J, Kalish LA, Mamisch TC, Kim YJ. Is the damage of cartilage a global or localized phenomenon in hip dysplasia, measured by dGEMRIC? Clin Orthop Relat Res. 2013 Jan; 471(1):301-7.
  22. Uluer AZ, Waltz DA, Kalish LA, Adams S, Gerard C, Ericson DA. Inhaled amiloride and tobramycin solutions fail to eradicate Burkholderia dolosa in patients with cystic fibrosis. J Cyst Fibros. 2013 Jan; 12(1):54-9.
  23. Chung S, Monteiro S, Ziniel SI, Kalish LA, Klaman P, Shannon M. Survey of emergency management professionals to assess ideal characteristics of a photographic-based family reunification tool. Disaster Med Public Health Prep. 2012 Jun; 6(2):156-62.
  24. Long M, Kalish LA, Neufeld EJ, Grace RF. Trends in anti-D immune globulin for childhood immune thrombocytopenia: usage, response rates, and adverse effects. Am J Hematol. 2012 Mar; 87(3):315-7.
  25. Guinan EC, Barbon CM, Kalish LA, Parmar K, Kutok J, Mancuso CJ, Stoler-Barak L, Suter EE, Russell JD, Palmer CD, Gallington LC, Voskertchian A, Vergilio JA, Cole G, Zhu K, D'Andrea A, Soiffer R, Weiss JP, Levy O. Bactericidal/permeability-increasing protein (rBPI21) and fluoroquinolone mitigate radiation-induced bone marrow aplasia and death. Sci Transl Med. 2011 Nov 23; 3(110):110ra118.
  26. Anderson DS, Kirchner M, Kellogg M, Kalish LA, Jeong JY, Vanasse G, Berliner N, Fleming MD, Steen H. Design and validation of a high-throughput matrix-assisted laser desorption ionization time-of-flight mass spectrometry method for quantification of hepcidin in human plasma. Anal Chem. 2011 Nov 01; 83(21):8357-62.
  27. Grace RF, Bennett CM, Ritchey AK, Jeng M, Thornburg CD, Lambert MP, Neier M, Recht M, Kumar M, Blanchette V, Klaassen RJ, Buchanan GR, Kurth MH, Nugent DJ, Thompson AA, Stine K, Kalish LA, Neufeld EJ. Response to steroids predicts response to rituximab in pediatric chronic immune thrombocytopenia. Pediatr Blood Cancer. 2012 Feb; 58(2):221-5.
  28. Grace RF, Long M, Kalish LA, Neufeld EJ. Applicability of 2009 international consensus terminology and criteria for immune thrombocytopenia to a clinical pediatric population. Pediatr Blood Cancer. 2012 Feb; 58(2):216-20.
  29. Levesque BM, Kalish LA, LaPierre J, Welch M, Porter V. Impact of implementing 5 potentially better respiratory practices on neonatal outcomes and costs. Pediatrics. 2011 Jul; 128(1):e218-26.
  30. Duro D, Mitchell PD, Kalish LA, Martin C, McCarthy M, Jaksic T, Dunn J, Brandt ML, Nobuhara KK, Sylvester KG, Moss RL, Duggan C. Risk factors for parenteral nutrition–associated liver disease following surgical therapy for necrotizing enterocolitis: A Glaser Pediatric Research Network Study [corrected]. J Pediatr Gastroenterol Nutr. 2011 May; 52(5):595-600.
  31. Passerotti CC, Kalish LA, Chow J, Passerotti AM, Recabal P, Cendron M, Lee RS, Lopez AB, Retik AB, Nguyen HT. The predictive value of the first postnatal ultrasound in children with antenatal hydronephrosis. J Pediatr Urol. 2011 Apr; 7(2):128-36.
  32. Harney KM, McCabe M, Branowicki P, Kalish LA, Neufeld EJ. Observational cohort study of pediatric inpatients with central venous catheters at "intermediate risk" of thrombosis and eligible for anticoagulant prophylaxis. J Pediatr Oncol Nurs. 2010 Nov-Dec; 27(6):325-9.
  33. Porter SC, Forbes P, Manzi S, Kalish LA. Patients providing the answers: narrowing the gap in data quality for emergency care. Qual Saf Health Care. 2010 Oct; 19(5):e34.
  34. Duro D, Kalish LA, Johnston P, Jaksic T, McCarthy M, Martin C, Dunn JC, Brandt M, Nobuhara KK, Sylvester KG, Moss RL, Duggan C. Risk factors for intestinal failure in infants with necrotizing enterocolitis: a Glaser Pediatric Research Network study. J Pediatr. 2010 Aug; 157(2):203-208.e1.
  35. Lebovidge JS, Strauch H, Kalish LA, Schneider LC. Assessment of psychological distress among children and adolescents with food allergy. J Allergy Clin Immunol. 2009 Dec; 124(6):1282-8.
  36. Fine AM, Kalish LA, Forbes P, Goldmann D, Mandl KD, Porter SC. Parent-driven technology for decision support in pediatric emergency care. Jt Comm J Qual Patient Saf. 2009 Jun; 35(6):307-15.
  37. Morrissey LK, Shea JO, Kalish LA, Weiner DL, Branowicki P, Heeney MM. Clinical practice guideline improves the treatment of sickle cell disease vasoocclusive pain. Pediatr Blood Cancer. 2009 Mar; 52(3):369-72.
  38. Deborah Chirnomas S, Geukes-Foppen M, Barry K, Braunstein J, Kalish LA, Neufeld EJ, Powell AJ. Practical implications of liver and heart iron load assessment by T2*-MRI in children and adults with transfusion-dependent anemias. Am J Hematol. 2008 Oct; 83(10):781-3.
  39. Moss RL, Kalish LA, Duggan C, Johnston P, Brandt ML, Dunn JC, Ehrenkranz RA, Jaksic T, Nobuhara K, Simpson BJ, McCarthy MC, Sylvester KG. Clinical parameters do not adequately predict outcome in necrotizing enterocolitis: a multi-institutional study. J Perinatol. 2008 Oct; 28(10):665-74.
  40. Gryllos I, Grifantini R, Colaprico A, Cary ME, Hakansson A, Carey DW, Suarez-Chavez M, Kalish LA, Mitchell PD, White GL, Wessels MR. PerR confers phagocytic killing resistance and allows pharyngeal colonization by group A Streptococcus. PLoS Pathog. 2008 Sep 05; 4(9):e1000145.
  41. LeBovidge JS, Timmons K, Rich C, Rosenstock A, Fowler K, Strauch H, Kalish LA, Schneider LC. Evaluation of a group intervention for children with food allergy and their parents. Ann Allergy Asthma Immunol. 2008 Aug; 101(2):160-5.
  42. Porter SC, Kaushal R, Forbes PW, Goldmann D, Kalish LA. Impact of a patient-centered technology on medication errors during pediatric emergency care. Ambul Pediatr. 2008 Sep-Oct; 8(5):329-35.
  43. Kalish LA. Methodological weaknesses in concluding that "small for gestational age" is an independent risk factor for parenteral nutrition-associated cholestasis. J Pediatr. 2008 Jul; 153(1):149; author reply 149-50.
  44. Levy H, Kalish LA, Cannon CL, García KC, Gerard C, Goldmann D, Pier GB, Weiss ST, Colin AA. Predictors of mucoid Pseudomonas colonization in cystic fibrosis patients. Pediatr Pulmonol. 2008 May; 43(5):463-71.
  45. Limperopoulos C, Bassan H, Kalish LA, Ringer SA, Eichenwald EC, Walter G, Moore M, Vanasse M, DiSalvo DN, Soul JS, Volpe JJ, du Plessis AJ. Current definitions of hypotension do not predict abnormal cranial ultrasound findings in preterm infants. Pediatrics. 2007 Nov; 120(5):966-77.
  46. Reller ME, Tauxe RV, Kalish LA, Mølbak K. Excess salmonellosis in women in the United States: 1968-2000. Epidemiol Infect. 2008 Aug; 136(8):1109-17.
  47. Hanson E, Kalish LA, Bunce E, Curtis C, McDaniel S, Ware J, Petry J. Use of complementary and alternative medicine among children diagnosed with autism spectrum disorder. J Autism Dev Disord. 2007 Apr; 37(4):628-36.
  48. Levy H, Kalish LA, Huntington I, Weller N, Gerard C, Silverman EK, Celedón JC, Pier GB, Weiss ST. Inflammatory markers of lung disease in adult patients with cystic fibrosis. Pediatr Pulmonol. 2007 Mar; 42(3):256-62.
  49. Macklin EA, Wayne PM, Kalish LA, Valaskatgis P, Thompson J, Pian-Smith MC, Zhang Q, Stevens S, Goertz C, Prineas RJ, Buczynski B, Zusman RM. Stop Hypertension with the Acupuncture Research Program (SHARP): results of a randomized, controlled clinical trial. Hypertension. 2006 Nov; 48(5):838-45.
  50. Guinan EC, Kalish LA, Berry WS, McDaniel S, Lehmann LE, Diller LR. A novel pattern of transaminase elevation associated with autologous transplant for neuroblastoma. Pediatr Transplant. 2006 Sep; 10(6):669-76.
  51. Angelone DF, Wessels MR, Coughlin M, Suter EE, Valentini P, Kalish LA, Levy O. Innate immunity of the human newborn is polarized toward a high ratio of IL-6/TNF-alpha production in vitro and in vivo. Pediatr Res. 2006 Aug; 60(2):205-9.
  52. Thierman JS, Clement GT, Kalish LA, O'Kane PL, Frauscher F, Paltiel HJ. Automated sonographic evaluation of testicular perfusion. Phys Med Biol. 2006 Jul 21; 51(14):3419-32.
  53. O'Rourke JM, Kalish LA, McDaniel S, Lyons B. The effects of exposure to environmental tobacco smoke on pulmonary function in children undergoing anesthesia for minor surgery. Paediatr Anaesth. 2006 May; 16(5):560-7.
  54. Paltiel HJ, Kalish LA, Susaeta RA, Frauscher F, O'Kane PL, Freitas-Filho LG. Pulse-inversion US imaging of testicular ischemia: quantitative and qualitative analyses in a rabbit model. Radiology. 2006 Jun; 239(3):718-29.
  55. Brown SD, Daly JC, Kalish LA, McDaniel SA. Financial disclosures of scientific papers presented at the 2003 RSNA Annual Meeting: association with reporting of non-Food and Drug Administration-approved uses of industry products. Radiology. 2006 Jun; 239(3):849-55.
  56. Lebovidge JS, Stone KD, Twarog FJ, Raiselis SW, Kalish LA, Bailey EP, Schneider LC. Development of a preliminary questionnaire to assess parental response to children's food allergies. Ann Allergy Asthma Immunol. 2006 Mar; 96(3):472-7.
  57. Kalish LA, Waltz DA, Dovey M, Potter-Bynoe G, McAdam AJ, Lipuma JJ, Gerard C, Goldmann D. Impact of Burkholderia dolosa on lung function and survival in cystic fibrosis. Am J Respir Crit Care Med. 2006 Feb 15; 173(4):421-5.
  58. Pocock SJ, Collier TJ, Dandreo KJ, de Stavola BL, Goldman MB, Kalish LA, Kasten LE, McCormack VA. Issues in the reporting of epidemiological studies: a survey of recent practice. BMJ. 2004 Oct 16; 329(7471):883.
  59. Asmuth DM, Busch MP, Laycock ME, Mohr BA, Kalish LA, van der Horst CM. Hepatitis B and C viral load changes following initiation of highly active antiretroviral therapy (HAART) in patients with advanced HIV infection. Antiviral Res. 2004 Aug; 63(2):123-31.
  60. Kalish LA, Buczynski B, Connell P, Gemmel A, Goertz C, Macklin EA, Pian-Smith M, Stevens S, Thompson J, Valaskatgis P, Wayne PM, Zusman RM. Stop Hypertension with the Acupuncture Research Program (SHARP): clinical trial design and screening results. Control Clin Trials. 2004 Feb; 25(1):76-103.
  61. Asmuth DM, Kalish LA, Laycock ME, Murphy EL, Mohr BA, Lee TH, Gallarda J, Giachetti C, Dollard SC, van der Horst CM, Grant RM, Busch MP. Absence of HBV and HCV, HTLV-I and -II, and human herpes virus-8 activation after allogeneic RBC transfusion in patients with advanced HIV-1 infection. Transfusion. 2003 Apr; 43(4):451-8.
  62. Ariga H, Lee TH, Laycock ME, Mohr BA, Kalish LA, Yomtovian R, Gernsheimer T, Busch MP. Residual WBC subsets in filtered prestorage RBCs. Transfusion. 2003 Jan; 43(1):98-106.
  63. Dzik WH, Anderson JK, O'Neill EM, Assmann SF, Kalish LA, Stowell CP. A prospective, randomized clinical trial of universal WBC reduction. Transfusion. 2002 Sep; 42(9):1114-22.
  64. Drew WL, Chou S, Miner RC, Mohr BA, Busch MP, van der Horst CM, Asmuth DM, Kalish LA. Cytomegalovirus glycoprotein B groups in human immunodeficiency virus-infected patients with incident retinitis. J Infect Dis. 2002 Jul 01; 186(1):114-7.
  65. Kennedy MS, Kalish LA, Mohandas K, Gernsheimer T, Townsend-McCall D. The transfusion trigger and number of units transfused in patients with HIV: associations with disease stage and functional status. Transfusion. 2002 Apr; 42(4):456-61.
  66. Eisenbud R, Assmann SF, Kalish LA, van Der Horst C, Collier AC. Differences in difficulty adjudicating clinical events in patients with advanced HIV disease. J Acquir Immune Defic Syndr. 2001 Sep 01; 28(1):43-6.
  67. Yomtovian R, Gernsheimer T, Assmann SF, Mohandas K, Lee TH, Kalish LA, Busch MP. WBC reduction in RBC concentrates by prestorage filtration: multicenter experience. Transfusion. 2001 Aug; 41(8):1030-6.
  68. Kruskall MS, Lee TH, Assmann SF, Laycock M, Kalish LA, Lederman MM, Busch MP. Survival of transfused donor white blood cells in HIV-infected recipients. Blood. 2001 Jul 15; 98(2):272-9.
  69. Murphy EL, Collier AC, Kalish LA, Assmann SF, Para MF, Flanigan TP, Kumar PN, Mintz L, Wallach FR, Nemo GJ. Highly active antiretroviral therapy decreases mortality and morbidity in patients with advanced HIV disease. Ann Intern Med. 2001 Jul 03; 135(1):17-26.
  70. Mohr BA, Feldman HA, Kalish LA, Longcope C, McKinlay JB. Are serum hormones associated with the risk of prostate cancer? Prospective results from the Massachusetts Male Aging Study. Urology. 2001 May; 57(5):930-5.
  71. Para MF, Kalish LA, Collier AC, Murphy EL, Drew WL. Correlates of change in cytomegalovirus viremia in patients with advanced human immunodeficiency virus infection who require transfusion. J Infect Dis. 2001 Jun 01; 183(11):1673-7.
  72. Para MF, Kalish LA, Collier AC, Pollard RB, Kumar PN, Mintz L, Wallach FR, Drew WL. Qualitative and quantitative PCR measures of cytomegalovirus in patients with advanced HIV infection who require transfusions. J Acquir Immune Defic Syndr. 2001 Apr 01; 26(4):320-5.
  73. Collier AC, Kalish LA, Busch MP, Gernsheimer T, Assmann SF, Lane TA, Asmuth DM, Lederman MM, Murphy EL, Kumar P, Kelley M, Flanigan TP, McMahon DK, Sacks HS, Kennedy MS, Holland PV. Leukocyte-reduced red blood cell transfusions in patients with anemia and human immunodeficiency virus infection: the Viral Activation Transfusion Study: a randomized controlled trial. JAMA. 2001 Mar 28; 285(12):1592-601.
  74. Kalish LA, McDougal WS, McKinlay JB. Family history and the risk of prostate cancer. Urology. 2000 Nov 01; 56(5):803-6.
  75. Chase C, Ware J, Hittelman J, Blasini I, Smith R, Llorente A, Anisfeld E, Diaz C, Fowler MG, Moye J, Kaligh LI. Early cognitive and motor development among infants born to women infected with human immunodeficiency virus. Women and Infants Transmission Study Group. Pediatrics. 2000 Aug; 106(2):E25.
  76. Kalish LA, Collier AC, Flanigan TP, Kumar PN. Plasma human immunodeficiency virus (HIV) type 1 RNA load in men and women with advanced HIV-1 disease. J Infect Dis. 2000 Aug; 182(2):603-6.
  77. Dunn DT, Simonds RJ, Bulterys M, Kalish LA, Moye J, de Maria A, Kind C, Rudin C, Denamur E, Krivine A, Loveday C, Newell ML. Interventions to prevent vertical transmission of HIV-1: effect on viral detection rate in early infant samples. AIDS. 2000 Jul 07; 14(10):1421-8.
  78. Lederman MM, Kalish LA, Asmuth D, Fiebig E, Mileno M, Busch MP. 'Modeling' relationships among HIV-1 replication, immune activation and CD4+ T-cell losses using adjusted correlative analyses. AIDS. 2000 May 26; 14(8):951-8.
  79. Kalish LA, McKinlay JB. Serum prostate-specific antigen levels (PSA) in men without clinical evidence of prostate cancer: age-specific reference ranges for total PSA, free PSA, and percent free PSA. Urology. 1999 Dec; 54(6):1022-7.
  80. Kalish LA, McIntosh K, Read JS, Diaz C, Landesman SH, Pitt J, Rich KC, Shearer WT, Davenny K, Lew JF. Evaluation of human immunodeficiency virus (HIV) type 1 load, CD4 T cell level, and clinical class as time-fixed and time-varying markers of disease progression in HIV-1-infected children. J Infect Dis. 1999 Nov; 180(5):1514-20.
  81. Anastos K, Kalish LA, Hessol N, Weiser B, Melnick S, Burns D, Delapenha R, DeHovitz J, Cohen M, Meyer W, Bremer J, Kovacs A. The relative value of CD4 cell count and quantitative HIV-1 RNA in predicting survival in HIV-1-infected women: results of the women's interagency HIV study. AIDS. 1999 Sep 10; 13(13):1717-26.
  82. Garcia PM, Kalish LA, Pitt J, Minkoff H, Quinn TC, Burchett SK, Kornegay J, Jackson B, Moye J, Hanson C, Zorrilla C, Lew JF. Maternal levels of plasma human immunodeficiency virus type 1 RNA and the risk of perinatal transmission. Women and Infants Transmission Study Group. N Engl J Med. 1999 Aug 05; 341(6):394-402.
  83. Anastos K, Kalish LA, Palacio H, Benson CA, Delapenha R, Chirgwin K, Stonis L, Telzak EE. Prevalence of and risk factors for tuberculin positivity and skin test anergy in HIV-1-infected and uninfected at-risk women. Women's Interagency HIV Study (WIHS). J Acquir Immune Defic Syndr. 1999 Jun 01; 21(2):141-7.
  84. Hanson IC, Antonelli TA, Sperling RS, Oleske JM, Cooper E, Culnane M, Fowler MG, Kalish LA, Lee SS, McSherry G, Mofenson L, Shapiro DE. Lack of tumors in infants with perinatal HIV-1 exposure and fetal/neonatal exposure to zidovudine. J Acquir Immune Defic Syndr Hum Retrovirol. 1999 Apr 15; 20(5):463-7.
  85. Palefsky JM, Minkoff H, Kalish LA, Levine A, Sacks HS, Garcia P, Young M, Melnick S, Miotti P, Burk R. Cervicovaginal human papillomavirus infection in human immunodeficiency virus-1 (HIV)-positive and high-risk HIV-negative women. J Natl Cancer Inst. 1999 Feb 03; 91(3):226-36.
  86. Telzak EE, Hershow R, Kalish LA, Hardy WD, Zuckerman E, Levine A, Delapenha R, DeHovitz J, Greenblatt RM, Anastos K. Seroprevalence of HTLV-I and HTLV-II among a cohort of HIV-infected women and women at risk for HIV infection. Women's Interagency HIV Study. J Acquir Immune Defic Syndr Hum Retrovirol. 1998 Dec 15; 19(5):513-8.
  87. Albert JM, Ioannidis JP, Reichelderfer P, Conway B, Coombs RW, Crane L, Demasi R, Dixon DO, Flandre P, Hughes MD, Kalish LA, Larntz K, Lin D, Marschner IC, Muñoz A, Murray J, Neaton J, Pettinelli C, Rida W, Taylor JM, Welles SL. Statistical issues for HIV surrogate endpoints: point/counterpoint. An NIAID workshop. Stat Med. 1998 Nov 15; 17(21):2435-62.
  88. Hershow RC, Kalish LA, Sha B, Till M, Cohen M. Hepatitis C virus infection in Chicago women with or at risk for HIV infection: evidence for sexual transmission. Sex Transm Dis. 1998 Nov; 25(10):527-32.
  89. Kalish LA, Boyer K, Brown G, Burns D, Diaz C, Hanson C, Landesman S, Matzen E, Tuomala R. Cigarette smoking and maternal-child HIV transmission. Women and Infants Transmission Study Group. J Acquir Immune Defic Syndr Hum Retrovirol. 1998 May 01; 18(1):86-9.
  90. Barkan SE, Melnick SL, Preston-Martin S, Weber K, Kalish LA, Miotti P, Young M, Greenblatt R, Sacks H, Feldman J. The Women's Interagency HIV Study. WIHS Collaborative Study Group. Epidemiology. 1998 Mar; 9(2):117-25.
  91. Shearer WT, Kalish LA, Zimmerman PA. CCR5 HIV-1 vertical transmission. Women and Infants Transmission Study Group. J Acquir Immune Defic Syndr Hum Retrovirol. 1998 Feb 01; 17(2):180-1.
  92. Kalish LA, Feldman HA. Number of phones for telephone randomization. Control Clin Trials. 1997 Aug; 18(4):380-1.
  93. Rich KC, Janda W, Kalish LA, Lew J, Hofheinz D, Landesman S, Pitt J, Diaz C, Moye J, Sullivan JL. Immune complex-dissociated p24 antigen in congenital or perinatal HIV infection: role in the diagnosis and assessment of risk of infection in infants. J Acquir Immune Defic Syndr Hum Retrovirol. 1997 Jul 01; 15(3):198-203.
  94. Tuomala RE, Kalish LA, Zorilla C, Fox H, Shearer W, Landay A, Vermund SH, Landesman S, Burns D. Changes in total, CD4+, and CD8+ lymphocytes during pregnancy and 1 year postpartum in human immunodeficiency virus-infected women. The Women and Infants Transmission Study. Obstet Gynecol. 1997 Jun; 89(6):967-74.
  95. Shearer WT, Quinn TC, LaRussa P, Lew JF, Mofenson L, Almy S, Rich K, Handelsman E, Diaz C, Pagano M, Smeriglio V, Kalish LA. Viral load and disease progression in infants infected with human immunodeficiency virus type 1. Women and Infants Transmission Study Group. N Engl J Med. 1997 May 08; 336(19):1337-42.
  96. Kalish LA, Pitt J, Lew J, Landesman S, Diaz C, Hershow R, Hollinger FB, Pagano M, Smeriglio V, Moye J. Defining the time of fetal or perinatal acquisition of human immunodeficiency virus type 1 infection on the basis of age at first positive culture. Women and Infants Transmission Study (WITS). J Infect Dis. 1997 Mar; 175(3):712-5.
  97. Cooper ER, Nugent RP, Diaz C, Pitt J, Hanson C, Kalish LA, Mendez H, Zorrilla C, Hershow R, Moye J, Smeriglio V, Fowler MG. After AIDS clinical trial 076: the changing pattern of zidovudine use during pregnancy, and the subsequent reduction in the vertical transmission of human immunodeficiency virus in a cohort of infected women and their infants. Women and Infants Transmission Study Group. J Infect Dis. 1996 Dec; 174(6):1207-11.
  98. Vlock DR, Andersen J, Kalish LA, Johnson JT, Kirkwood JM, Whiteside T, Herberman RB, Adams GS, Oken MM, Haselow RE. Phase II trial of interferon-alpha in locally recurrent or metastatic squamous cell carcinoma of the head and neck: immunological and clinical correlates. J Immunother Emphasis Tumor Immunol. 1996 Nov; 19(6):433-42.
  99. Landesman SH, Kalish LA, Burns DN, Minkoff H, Fox HE, Zorrilla C, Garcia P, Fowler MG, Mofenson L, Tuomala R. Obstetrical factors and the transmission of human immunodeficiency virus type 1 from mother to child. The Women and Infants Transmission Study. N Engl J Med. 1996 Jun 20; 334(25):1617-23.
  100. McIntosh K, Comeau AM, Wara D, Diaz C, Landesman S, Pitt J, Rich K, Lew J, Moye J, Kalish LA. The utility of IgA antibody to human immunodeficiency virus type 1 in early diagnosis of vertically transmitted infection. National Institute of Allergy and Infectious Diseases and National Institute of Child Health and Human Development Women and Infants Transmission Study Group. Arch Pediatr Adolesc Med. 1996 Jun; 150(6):598-602.
  101. Mauch PM, Kalish LA, Marcus KC, Coleman CN, Shulman LN, Krill E, Come S, Silver B, Canellos GP, Tarbell NJ. Second malignancies after treatment for laparotomy staged IA-IIIB Hodgkin's disease: long-term analysis of risk factors and outcome. Blood. 1996 May 01; 87(9):3625-32.
  102. Moye J, Rich KC, Kalish LA, Sheon AR, Diaz C, Cooper ER, Pitt J, Handelsman E. Natural history of somatic growth in infants born to women infected by human immunodeficiency virus. Women and Infants Transmission Study Group. J Pediatr. 1996 Jan; 128(1):58-69.
  103. Lynch T, Kalish L, Mentzer S, Decamp M, Strauss G, Sugarbaker D. Optimal therapy of malignant pleural effusions. Int J Oncol. 1996 Jan; 8(1):183-90.
  104. Gertz MA, Kalish LA, Kyle RA, Hahn RG, Tormey DC, Oken MM. Phase III study comparing vincristine, doxorubicin (Adriamycin), and dexamethasone (VAD) chemotherapy with VAD plus recombinant interferon alfa-2 in refractory or relapsed multiple myeloma. An Eastern Cooperative Oncology Group study. Am J Clin Oncol. 1995 Dec; 18(6):475-80.
  105. Mauch PM, Kalish LA, Marcus KC, Shulman LN, Krill E, Tarbell NJ, Silver B, Weinstein H, Come S, Canellos GP, Coleman CN. Long-term survival in Hodgkin's disease relative impact of mortality, second tumors, infection, and cardiovascular disease. Cancer J Sci Am. 1995 May-Jun; 1(1):33-42.
  106. Lew MA, Kehoe K, Ritz J, Antman KH, Nadler L, Kalish LA, Finberg R. Ciprofloxacin versus trimethoprim/sulfamethoxazole for prophylaxis of bacterial infections in bone marrow transplant recipients: a randomized, controlled trial. J Clin Oncol. 1995 Jan; 13(1):239-50.
  107. Marcus KC, Kalish LA, Coleman CN, Shulman LN, Rosenthal DS, Canellos GP, Mauch PM. Improved survival in patients with limited stage IIIA Hodgkin's disease treated with combined radiation therapy and chemotherapy. J Clin Oncol. 1994 Dec; 12(12):2567-72.
  108. Tepler I, Elias A, Kalish L, Shulman L, Strauss G, Skarin A, Lynch T, Levitt D, Resta D, Demetri G, et al. Effect of recombinant human interleukin-3 on haematological recovery from chemotherapy-induced myelosuppression. Br J Haematol. 1994 Aug; 87(4):678-86.
  109. Shulman LN, Buswell L, Goodman H, Muto M, Berkowitz R, Teicher B, Kusumoto T, Hurwitz SJ, Kalish LA, Coleman CN. Phase I pharmacokinetic study of the hypoxic cell sensitizer etanidazole with carboplatin and cyclophosphamide in the treatment of advanced ovarian cancer. Int J Radiat Oncol Biol Phys. 1994 Jun 15; 29(3):545-8.
  110. Shulman LN, Buswell L, Kalish LA, Coleman CN. Use of the hypoxic cell sensitizer etanidazole (SR-2508) with intravenous melphalan and prednisone in the treatment of multiple myeloma: a pharmacokinetic study. Int J Radiat Oncol Biol Phys. 1994 Jun 15; 29(3):541-3.
  111. Lenhard RE, Daniels MJ, Oken MM, Glick JH, Ettinger DS, Kalish L, O'Connell MJ. An aggressive high dose cyclophosphamide and prednisone regimen for advanced multiple myeloma. Leuk Lymphoma. 1994 May; 13(5-6):485-9.
  112. Lenhard RE, Kalish LA, Oken MM, Ettinger DS, Glick J. Timed-sequential high-dose cyclophosphamide and vincristine in the treatment of multiple myeloma. Cancer. 1994 Apr 15; 73(8):2113-8.
  113. Lynch TJ, Kalish LA, Kass F, Strauss G, Elias A, Skarin A, Shulman L, Sugarbaker D, Frei E. Continuous-infusion cisplatin, 5-fluorouracil, and leucovorin for advanced non-small cell lung cancer. Cancer. 1994 Feb 15; 73(4):1171-6.
  114. Lynch TJ, Kalish L, Strauss G, Elias A, Skarin A, Shulman LN, Posner M, Frei E. Phase II study of topotecan in metastatic non-small-cell lung cancer. J Clin Oncol. 1994 Feb; 12(2):347-52.
  115. Ballen KK, Gilliland DG, Kalish LA, Shulman LN. Bone marrow dysplasia in patients with newly diagnosed acute myelogenous leukemia does not correlate with history of myelodysplasia or with remission rate and survival. Cancer. 1994 Jan 15; 73(2):314-21.
  116. Adelstein DJ, Kalish LA, Adams GL, Wagner H, Oken MM, Remick SC, Mansour EG, Haselow RE. Concurrent radiation therapy and chemotherapy for locally unresectable squamous cell head and neck cancer: an Eastern Cooperative Oncology Group pilot study. J Clin Oncol. 1993 Nov; 11(11):2136-42.
  117. Lynch TJ, Kass F, Kalish LA, Elias AD, Strauss G, Shulman LN, Sugarbaker DJ, Skarin A, Frei E. Cisplatin, 5-fluorouracil, and etoposide for advanced non-small cell lung cancer. Cancer. 1993 May 15; 71(10):2953-7.
  118. Healey EA, Tarbell NJ, Kalish LA, Silver B, Rosenthal DS, Marcus K, Shulman LN, Coleman CN, Canellos G, Weinstein H, et al. Prognostic factors for patients with Hodgkin disease in first relapse. Cancer. 1993 Apr 15; 71(8):2613-20.
  119. Mauch PM, Kalish LA, Kadin M, Coleman CN, Osteen R, Hellman S. Patterns of presentation of Hodgkin disease. Implications for etiology and pathogenesis. Cancer. 1993 Mar 15; 71(6):2062-71.
  120. Lynch TJ, Clark JR, Kalish LA, Fallon BG, Elias AD, Skarin A, Frei E. Continuous-infusion cisplatin, 5-fluorouracil, and bolus methotrexate in the treatment of advanced non-small cell lung cancer. Cancer. 1992 Oct 01; 70(7):1880-5.
  121. Kantoff PW, Kalish LA, McDowell-Bryant P, Canellos GP, Gibbs R, Richie JP, Garnick MB. Long-term followup of 150 patients with testicular cancer treated at a single institution. J Urol. 1992 Jan; 147(1):82-8.
  122. Stomper PC, Kalish LA, Garnick MB, Richie JP, Kantoff PW. CT and pathologic predictive features of residual mass histologic findings after chemotherapy for nonseminomatous germ cell tumors: can residual malignancy or teratoma be excluded? Radiology. 1991 Sep; 180(3):711-4.
  123. Lew MA, Kehoe K, Ritz J, Antman KH, Nadler L, Takvorian T, Mayer R, Kalish L, Finberg R. Prophylaxis of bacterial infections with ciprofloxacin in patients undergoing bone marrow transplantation. Transplantation. 1991 Mar; 51(3):630-6.
  124. Kalish LA. Efficient design for estimation of median lethal dose and quantal dose-response curves. Biometrics. 1990 Sep; 46(3):737-48.
  125. Kalish LA. Reducing mean squared error in the analysis of pair-matched case-control studies. Biometrics. 1990 Jun; 46(2):493-9.
  126. Kalish LA. Permutation tests following restricted randomization procedures. Control Clin Trials. 1990 Apr; 11(2):147-52.
  127. Rieker PP, Fitzgerald EM, Kalish LA. Adaptive behavioral responses to potential infertility among survivors of testis cancer. J Clin Oncol. 1990 Feb; 8(2):347-55.
  128. Rieker PP, Fitzgerald EM, Kalish LA, Richie JP, Lederman GS, Edbril SD, Garnick MB. Psychosocial factors, curative therapies, and behavioral outcomes. A comparison of testis cancer survivors and a control group of healthy men. Cancer. 1989 Dec 01; 64(11):2399-407.
  129. Kalish LA, Harrington DP. Efficiency of balanced treatment allocation for survival analysis. Biometrics. 1988 Sep; 44(3):815-21.
  130. Fung CY, Kalish LA, Brodsky GL, Richie JP, Garnick MB. Stage I nonseminomatous germ cell testicular tumor: prediction of metastatic potential by primary histopathology. J Clin Oncol. 1988 Sep; 6(9):1467-73.
  131. Kalish LA, Garnick MB, Richie JP. Appropriate endpoints for superficial bladder cancer clinical trials. J Clin Oncol. 1987 Dec; 5(12):2004-8.
  132. Richie JP, Socinsky MA, Fung CY, Brodsky GL, Kalish LA, Garnick MB. Management of patients with clinical stage I or II nonseminomatous germ cell tumors of the testis. Evolving therapeutic options. Arch Surg. 1987 Dec; 122(12):1443-5.
  133. Kalish LA, Begg CB. The impact of treatment allocation procedures on nominal significance levels and bias. Control Clin Trials. 1987 Jun; 8(2):121-35.
  134. Kalish LA, Begg CB. Evaluation of efficient designs for observational epidemiologic studies. Biometrics. 1987 Mar; 43(1):145-67.
  135. Gilchrist KW, Kalish L, Gould VE, Hirschl S, Imbriglia JE, Levy WM, Patchefsky AS, Pickren J, Roth JA, Schinella RA, et al. Immunostaining for carcinoembryonic antigen does not discriminate for early recurrence in breast cancer. The ECOG experience. Cancer. 1985 Jul 15; 56(2):351-5.
  136. Taylor SG, Kalish LA, Olson JE, Cummings F, Bennett JM, Falkson G, Tormey DC, Carbone PP. Adjuvant CMFP versus CMFP plus tamoxifen versus observation alone in postmenopausal, node-positive breast cancer patients: three-year results of an Eastern Cooperative Oncology Group study. J Clin Oncol. 1985 Feb; 3(2):144-54.
  137. Pandya KJ, McFadden ET, Kalish LA, Tormey DC, Taylor SG, Falkson G. A retrospective study of earliest indicators of recurrence in patients on Eastern Cooperative Oncology Group adjuvant chemotherapy trials for breast cancer. A preliminary report. Cancer. 1985 Jan 01; 55(1):202-5.
  138. Begg CB, Kalish LA. Treatment allocation for nonlinear models in clinical trials: the logistic model. Biometrics. 1984 Jun; 40(2):409-20.
  139. Kalish LA. Relationships of body size with breast cancer. J Clin Oncol. 1984 Apr; 2(4):287-93.
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