We study mitochondrial disorders, a large group of chronic disorders affecting mitochondria, the cellular machines that produce energy throughout the body. Our research is focused on the clinical presentation of children with mitochondrial disorders and their response to therapy with different medications and vitamins/supplements.
Currently I am a principal investigator in a study examining the ability of the drug dichloroacetate (DCA) to treat children with mitochondrial disorders complicated by lactic acidemia, a condition in which excess lactate builds up in the blood and spinal fluid. DCA reduces lactate levels and thus has the potential to alleviate disease symptoms. I evaluate children in clinic, enroll them in the protocol and follow them in the Mitochondrial Program while they are being maintained on DCA.
About Irina Anselm
Irina Anselm received her MD from St. Petersburg Pediatric Medical Academy. She completed an internship and residency in pediatrics at UMASS Medical Center and a fellowship in child neurology at Floating Hospital for Children at the New England Medical Center.