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RESEARCH + INNOVATION

Research

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Grace Chan, MD, MPH, PhD

Grace Chan MD
Department:
Medicine Research
Division
Medicine Critical Care Research
Hospital Title:
Staff Physician
Academic Title:
Assistant Professor in Pediatrics, Harvard Medical School

Research Overview

Dr. Chan’s research aims to advance child health in underserved populations by using epidemiologic methods to study and develop evidence-based strategies. Her research has focused on reducing the three major causes of neonatal mortality – complications of prematurity, intrapartum-related complications, and infections - and delivering effective programs for newborn survival. She has led and evaluated newborn survival projects and trained health care workers on essential newborn care practices in Tanzania, India, and Indonesia. With Saving Newborn Lives, she is currently developing strategies to scale effective implementation of Kangaroo Mother Care for preterm newborns. Prior to joining Harvard, she was a NIH Clinical Research Scholar at Johns Hopkins where she collaborated with the International Centre for Diarrheal Disease Research in Bangladesh (ICDDR, B) to estimate the risk of early-onset neonatal sepsis from maternal infections in Dhaka.

About Grace Chan, MD, MPH, PhD

Dr. Chan is a graduate of Harvard College and Harvard Medical School. She trained in pediatrics in the Boston Combined Residency Program. Following residency, she completed her PhD and post-doctoral work at Johns Hopkins School of Public Health and a research fellowship at ICDDRB.

Key Publications

  • Chan GJ, Moulton LH, Becker S, Muñoz A, Black R. Non-specific effects of diphtheria-tetanus-pertussis vaccination on child mortality in Cebu, The Philippines. International Journal of Epidemiology, 2007; 36(5):1022-1029.
  • Chan GJ, Parco K, Sihombing M, Tredwell S, O’Rourke E. Improving health services to displaced persons in Aceh, Indonesia: A Balanced Scorecard. Bulletin of the World Health Organization, 2010; 88(9):709-712.
  • Chan GJ, Lee AC, Baqui AH, Tan J, Black RE. Risk of early-onset neonatal infection with maternal infection or colonization: a global systematic review and meta-analysis. PLoS medicine, 2013; 10(8):e1001502. Epub 2013/08/27.
  • Chan GJ, Modak JK, Mahmud AA, Baqui AH, Black RE, Saha SK. Maternal and neonatal colonization in Bangladesh: prevalences, etiologies and risk factors. Journal of perinatology, 2013; Epub 2013/08/31.
  • Chan GJ, Baqui AH, Modak JK, Murillo-Chaves A, Mahmud AA, et al. Early-onset neonatal sepsis in Dhaka, Bangladesh: risk associated with maternal bacterial colonization and chorioamnionitis. Trop Med Int Health, 2013; 18: 1057-1064.
  • Chan GJ, Stuart EA, Zaman M, Mahmud AA, Baqui AH, Black RE. The effect of intrapartum antibiotics on early-onset neonatal sepsis in Dhaka, Bangladesh: A propensity score matched analysis.BMC Pediatrics, 2014; 14:104

Publications

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  1. Smith ER, Bergelson I, Constantian S, Valsangkar B, Chan GJ. Barriers and enablers of health system adoption of kangaroo mother care: a systematic review of caregiver perspectives. BMC Pediatr. 2017 Jan 25; 17(1):35.
  2. Chan GJ, Valsangkar B, Kajeepeta S, Boundy EO, Wall S. What is kangaroo mother care? Systematic review of the literature. J Glob Health. 2016 Jun; 6(1):010701.
  3. Muhihi A, Sudfeld CR, Smith ER, Noor RA, Mshamu S, Briegleb C, Bakari M, Masanja H, Fawzi W, Chan GJ. Risk factors for small-for-gestational-age and preterm births among 19,269 Tanzanian newborns. BMC Pregnancy Childbirth. 2016 May 17; 16:110.
  4. Boundy EO, Dastjerdi R, Spiegelman D, Fawzi WW, Missmer SA, Lieberman E, Kajeepeta S, Wall S, Chan GJ. Kangaroo Mother Care and Neonatal Outcomes: A Meta-analysis. Pediatrics. 2016 Jan; 137(1).
  5. Chan GJ, Labar AS, Wall S, Atun R. Kangaroo mother care: a systematic review of barriers and enablers. Bull World Health Organ. 2016 Feb 01; 94(2):130-141J.
  6. Reisman J, Martineau N, Kairuki A, Mponzi V, Meda AR, Isangula KG, Thomas E, Plotkin M, Chan GJ, Davids L, Msemo G, Azayo M, Nelson BD. Validation of a novel tool for assessing newborn resuscitation skills among birth attendants trained by the Helping Babies Breathe program. Int J Gynaecol Obstet. 2015 Nov; 131(2):196-200.
  7. Chan GJ, Lee AC, Baqui AH, Tan J, Black RE. Prevalence of early-onset neonatal infection among newborns of mothers with bacterial infection or colonization: a systematic review and meta-analysis. BMC Infect Dis. 2015 Mar 07; 15:118.
  8. Chan GJ, Stuart EA, Zaman M, Mahmud AA, Baqui AH, Black RE. The effect of intrapartum antibiotics on early-onset neonatal sepsis in Dhaka, Bangladesh: a propensity score matched analysis. BMC Pediatr. 2014 Apr 17; 14:104.
  9. Flynn JT, Ng DK, Chan GJ, Samuels J, Furth S, Warady B, Greenbaum LA. The effect of abnormal birth history on ambulatory blood pressure and disease progression in children with chronic kidney disease. J Pediatr. 2014 Jul; 165(1):154-162.e1.
  10. Chan GJ, Modak JK, Mahmud AA, Baqui AH, Black RE, Saha SK. Maternal and neonatal colonization in Bangladesh: prevalences, etiologies and risk factors. J Perinatol. 2013 Dec; 33(12):971-6.
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  11. Chan GJ, Lee AC, Baqui AH, Tan J, Black RE. Risk of early-onset neonatal infection with maternal infection or colonization: a global systematic review and meta-analysis. PLoS Med. 2013 Aug; 10(8):e1001502.
  12. Chan GJ, Baqui AH, Modak JK, Murillo-Chaves A, Mahmud AA, Boyd TK, Black RE, Saha SK. Early-onset neonatal sepsis in Dhaka, Bangladesh: risk associated with maternal bacterial colonisation and chorioamnionitis. Trop Med Int Health. 2013 Sep; 18(9):1057-1064.
  13. Chan GJ, Parco KB, Sihombing ME, Tredwell SP, O'Rourke EJ. Improving health services to displaced persons in Aceh, Indonesia: a balanced scorecard. Bull World Health Organ. 2010 Sep 01; 88(9):709-12.
  14. Chan GJ, Moulton LH, Becker S, Muñoz A, Black RE. Non-specific effects of diphtheria tetanus pertussis vaccination on child mortality in Cebu, The Philippines. Int J Epidemiol. 2007 Oct; 36(5):1022-9.
  15. Glass RJ, Chan G, Rentz D. Cognitive impairment screening in second offense DUI programs. J Subst Abuse Treat. 2000 Dec; 19(4):369-73.
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