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Gloria McAnulty, PhD

Gloria McAnulty, PhD
Lab:
Als Laboratory
Department:
Psychiatry
Division
Psychology Research
Hospital Title:
Staff Scientist; Associate Director, Neurobehavioral Infant & Child Studies
Academic Title:
Assistant Professor of Psychology in the Department of Psychiatry, Harvard Medical
Research Focus Area:
Newborn Development and InterventionDevelopmental NeurophysiologyDevelopment and Learning DisabilitiesADHDPrematurity
Contact:
617-355-8249
Contact Via Email
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Research Overview

As a research neuropsychologist with background in statistical analysis and design methodologies, Dr. McAnulty’s primary research focus has been the development and evaluation of two innovative approaches to clinical diagnosis of neurological diseases and neurobehavioral disorders: quantified EEG (qEEG) and the Assessment of Preterm Infants’ Behavior (APIB).

Her research interests also include the intersection of neurocognitive function, qEEG and advanced MR imaging technology in disorders including brain tumor, schizophrenia, Alzheimer’s disease, depression, dyslexia and autism as well as healthy aging.

As a licensed neuropsychologist with clinical expertise in infancy, prematurity and high-risk birth, her second focus has been in the development, evaluation and dissemination of a field changing approach to NICU care delivery, Newborn Individualized Care and Assessment Program (NIDCAP).

She serves as site Principal Investigator of a multi-disciplinary NIH/NIMH research project whose goal is to develop clinically feasible time efficient methods for the fast acquisition of diffusion magnetic resonance imaging of pediatric patients and apply it to study the neuropathology in attention-deficit hyperactivity-disorder.

About Gloria McAnulty

As a research neuropsychologist with background in research design and analysis, I have been involved in the development and evaluation of two innovative approaches to clinical diagnosis of neurological diseases and neurobehavioral disorders: quantified EEG (qEEG) and the Assessment of Preterm Infants' Behavior (APIB). I began my career at Boston Children's Hospital working with qEEG's neurologist originator, Frank Duffy, MD evaluating qEEG's diagnostic sensitivity for disorders including brain tumor, schizophrenia, Alzheimer's disease, depression, dyslexia and autism as well as healthy aging. I worked on its statistical development with quantified mapping, unrestricted principal component and coherence analyses. This area grew to include MR imaging technology to define anatomical relationship to brain function findings.
As a clinical neuropsychologist with expertise in prematurity and high-risk birth, my work involves the development, evaluation and dissemination of a field changing approach to NICU care, Newborn Individualized Care and Assessment Program (NIDCAP). I have had the opportunity to evaluate a preterm infant diagnostic assessment (APIB) and participate in the quality assurance and dissemination of a system changing approach developed from the same theoretical model with the model's originator, Heidelise Als, PhD, serving as collaborator and Associate Director of the research laboratory Neurobehavioral Infant and Child Studies.

Publications

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  1. Duffy FH, Shankardass A, McAnulty GB, Eksioglu YZ, Coulter D, Rotenberg A, Als H. Corticosteroid therapy in regressive autism: a retrospective study of effects on the Frequency Modulated Auditory Evoked Response (FMAER), language, and behavior. BMC Neurol. 2014 May 15; 14:70.
  2. Lawhon G, Helm JM, Buehler D, McAnulty G, Kosta S, Alberts JR, Als H, Mader S, Daly M, Sizun J, Vandenberg K, Warren I. NIDCAP Federation International response. Pediatrics. 2013 Aug; 132(2):e550-1.
  3. Duffy FH, Shankardass A, McAnulty GB, Als H. The relationship of Asperger's syndrome to autism: a preliminary EEG coherence study. BMC Med. 2013 Jul 31; 11:175.
  4. McAnulty G, Duffy FH, Kosta S, Weisenfeld NI, Warfield SK, Butler SC, Alidoost M, Bernstein JH, Robertson R, Zurakowski D, Als H. School-age effects of the newborn individualized developmental care and assessment program for preterm infants with intrauterine growth restriction: preliminary findings. BMC Pediatr. 2013 Feb 19; 13:25.
  5. Als H, Duffy FH, McAnulty G, Butler SC, Lightbody L, Kosta S, Weisenfeld NI, Robertson R, Parad RB, Ringer SA, Blickman JG, Zurakowski D, Warfield SK. NIDCAP improves brain function and structure in preterm infants with severe intrauterine growth restriction. J Perinatol. 2012 Oct; 32(10):797-803.
  6. McAnulty G, Duffy FH, Kosta S, Weisenfeld NI, Warfield SK, Butler SC, Bernstein JH, Zurakowski D, Als H. School Age Effects of the Newborn Individualized Developmental Care and Assessment Program for Medically Low-Risk Preterm Infants: Preliminary Findings. J Clin Neonatol. 2012; 1(4):184-194.
  7. Als H, McAnulty GB. The Newborn Individualized Developmental Care and Assessment Program (NIDCAP) with Kangaroo Mother Care (KMC): Comprehensive Care for Preterm Infants. Curr Womens Health Rev. 2011 Aug; 7(3):288-301.
  8. Duffy FH, McAnulty GB, McCreary MC, Cuchural GJ, Komaroff AL. EEG spectral coherence data distinguish chronic fatigue syndrome patients from healthy controls and depressed patients--a case control study. BMC Neurol. 2011 Jul 01; 11:82.
  9. Ferber SG, Als H, McAnulty G, Peretz H, Zisapel N. Melatonin and mental capacities in newborn infants. J Pediatr. 2011 Jul; 159(1):99-103.e1.
  10. Als H, Duffy FH, McAnulty GB, Fischer CB, Kosta S, Butler SC, Parad RB, Blickman JG, Zurakowski D, Ringer SA. Is the Newborn Individualized Developmental Care and Assessment Program (NIDCAP) effective for preterm infants with intrauterine growth restriction? J Perinatol. 2011 Feb; 31(2):130-6.
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  12. McAnulty G, Duffy FH, Butler S, Parad R, Ringer S, Zurakowski D, Als H. Individualized developmental care for a large sample of very preterm infants: health, neurobehaviour and neurophysiology. Acta Paediatr. 2009 Dec; 98(12):1920-6.
  13. McAnulty GB, Duffy FH, Butler SC, Bernstein JH, Zurakowski D, Als H. Effects of the Newborn Individualized Developmental Care and Assessment Program (NIDCAP) at age 8 years: preliminary data. Clin Pediatr (Phila). 2010 Mar; 49(3):258-70.
  14. Mewes AU, Hüppi PS, Als H, Rybicki FJ, Inder TE, McAnulty GB, Mulkern RV, Robertson RL, Rivkin MJ, Warfield SK. Regional brain development in serial magnetic resonance imaging of low-risk preterm infants. Pediatrics. 2006 Jul; 118(1):23-33.
  15. Lisa McElaney, Principal Investigator; Heidelise Als, Co-Principal Investigator, Gloria McAnulty, Investigator; Allie Hamenuk, Producer; Katherine Rose, Co-Producer. . Focus on the Brain, Part 1: The Science of Preterm Infant Development. Part 2: Clinical Care Practices for Special Care Nurseries. Part 3: No Matter How Small. A Parent Guide to Preterm Infant Development. Additional: Focus on the Brain: Professional Resources [DVD 3 part series and CD additional section]. 2006.
  16. Mewes AUJ, Als H, McAnulty G, Inder T, Hüppi P, Rybicki MD, Warfield, S. Regional brain development of low-risk preterm infants differs from fullterm infants. Abstract 2005 Pediatric Academic Societies' Meeting. 2005.
  17. Als H, Butler S, Kosta S, McAnulty G. The Assessment of Preterm Infants' Behavior (APIB): furthering the understanding and measurement of neurodevelopmental competence in preterm and full-term infants. Ment Retard Dev Disabil Res Rev. 2005; 11(1):94-102.
  18. Rivkin MJ, Wolraich D, Als H, McAnulty G, Butler S, Conneman N, Fischer C, Vajapeyam S, Robertson RL, Mulkern RV. Prolonged T*2 values in newborn versus adult brain: Implications for fMRI studies of newborns. Magn Reson Med. 2004 Jun; 51(6):1287-91.
  19. Als H, Duffy FH, McAnulty GB, Rivkin MJ, Vajapeyam S, Mulkern RV, Warfield SK, Huppi PS, Butler SC, Conneman N, Fischer C, Eichenwald EC. Early experience alters brain function and structure. Pediatrics. 2004 Apr; 113(4):846-57.
  20. Als H, Gilkerson L, Duffy FH, McAnulty GB, Buehler DM, Vandenberg K, Sweet N, Sell E, Parad RB, Ringer SA, Butler SC, Blickman JG, Jones KJ. A three-center, randomized, controlled trial of individualized developmental care for very low birth weight preterm infants: medical, neurodevelopmental, parenting, and caregiving effects. J Dev Behav Pediatr. 2003 Dec; 24(6):399-408.
  21. Peters JM, Waber DP, McAnulty GB, Duffy FH. Event-related correlations in learning impaired children during A hybrid go/no-go choice reaction visual-motor task. Clin Electroencephalogr. 2003 Jul; 34(3):99-109.
  22. Butler SC, Als H, McAnulty GB, Duffy FH, Conneman N, Fischer C, Eichenwald E, Warfield S, Mulkern RV, Hüppi P, Rivkin MJ. Effectiveness of individualized developmental care for preterm infants: Neurobehavioral and neurostructural evidence. Abstract Proceedings, Biennial Meeting for the Society for Research in Child Development. 2003.
  23. Duffy FH, Als H, McAnulty GB. Infant EEG spectral coherence data during quiet sleep: unrestricted principal components analysis--relation of factors to gestational age, medical risk, and neurobehavioral status. Clin Electroencephalogr. 2003 Apr; 34(2):54-69.
  24. Als H, Duffy FH, McAnulty GB, Kosta S, Fischer C, Conneman N, Butler S, Rivkin MJ, Warfield S, Vajapeyam S, Mulkern RV, Eichenwald E, Mazzawi J, Metcalfe M, Blickman J, Hüppi P, Inder TE, Chen H. Earliest brain development and experience: Behavior, qEEG, and MRI. Abstract Proceedings, Thirteenth Annual NIDCAP Trainers Meeting, NIDCAP Federation International. 2002.
  25. Rivkin MJ, Wolraich D, Als H, Butler S, Conneman N, McAnulty G, Vajapeyam S, Fischer C, Robertson R, Mulkern RV. Prolonged T2* Values in Newborns vs Adult brain: Implications for fMRI Studies of Newborns. Proceedings of the International Society for Magnetic Resonance in Medicine 10th Scientific Meeting. 2002.
  26. Vajapeyam S, Rivkin MJ, McAnulty G, Fischer C, Butler S, Conneman N, Wolraich D, Robertson R, Mulkern RV, Maier S, Als H. DTI Study of the Premature Infant Brain Shows Change in Diffusion Properties of White Matter May Precede Myelination. Proceedings. ISMRM 10th Scientific Meeting. 2002.
  27. Valencia I, McAnulty GB, Waber DP, Duffy FH. Auditory evoked responses to similar words with phonemic difference: comparison between children with good and poor reading scores. Clin Electroencephalogr. 2001 Jul; 32(3):160-7.
  28. Duffy FH, Valencia I, McAnulty GB, Waber DP. Auditory evoked response data reduction by PCA: development of variables sensitive to reading disability. Clin Electroencephalogr. 2001 Jul; 32(3):168-78.
  29. Duffy FH, McAnulty GB, Waber DP. Auditory evoked responses to single tones and closely spaced tone pairs in children grouped by reading or matrices abilities. Clin Electroencephalogr. 1999 Jul; 30(3):84-93.
  30. Als H, Duffy FH, McAnulty GB. Effectiveness of individualized neurodevelopmental care in the newborn intensive care unit (NICU). Acta Paediatr Suppl. 1996 Oct; 416:21-30.
  31. Duffy FH, Mcanulty GB, Albert MS. Effects of age upon interhemispheric EEG coherence in normal adults. Neurobiol Aging. 1996 Jul-Aug; 17(4):587-99.
  32. Buehler DM, Als H, Duffy FH, McAnulty GB, Liederman J. Effectiveness of individualized developmental care for low-risk preterm infants: behavioral and electrophysiologic evidence. Pediatrics. 1995 Nov; 96(5 Pt 1):923-32.
  33. Duffy FH, McAnulty GB, Albert MS. Temporoparietal electrophysiological differences characterize patients with Alzheimer's disease: a split-half replication study. Cereb Cortex. 1995 May-Jun; 5(3):215-21.
  34. Duffy FH, Jones KJ, McAnulty GB, Albert MS. Spectral coherence in normal adults: unrestricted principal components analysis; relation of factors to age, gender, and neuropsychologic data. Clin Electroencephalogr. 1995 Jan; 26(1):30-46.
  35. Als H, Lawhon G, Duffy FH, McAnulty GB, Gibes-Grossman R, Blickman JG. . Developmental care for very low-birth-weight infants. Journal of the American Medical Association. 1995; 273:1577-78.
  36. Als H, Lawhon G, Duffy FH, McAnulty GB, Gibes-Grossman R, Blickman JG. Individualized developmental care for the very low-birth-weight preterm infant. Medical and neurofunctional effects. JAMA. 1994 Sep 21; 272(11):853-8.
  37. Jones K, Duffy FH, McAnulty GB, Albert MS. The principal component reduction of extremely large numbers of qEEG variables to meaningful factors. Proceedings of the American Statistical Association. 1994.
  38. Duffy FH, McAnulty GB, Jones K, Als H, Albert M. Brain electrical correlates of psychological measures: strategies and problems. Brain Topogr. 1993; 5(4):399-412.
  39. Duffy FH, McAnulty GB, Albert MS. The pattern of age-related differences in electrophysiological activity of healthy males and females. Neurobiol Aging. 1993 Jan-Feb; 14(1):73-84.
  40. Vasile RG, Duffy FH, McAnulty G, Mooney JJ, Bloomingdale K, Schildkraut JJ. Abnormal flash visual evoked response in melancholia: a replication study. Biol Psychiatry. 1992 Feb 15; 31(4):325-36.
  41. Duffy FH, Jones K, Bartels P, McAnulty G, Albert M. Unrestricted principal components analysis of brain electrical activity: issues of data dimensionality, artifact, and utility. Brain Topogr. 1992; 4(4):291-307.
  42. Badian NA, Duffy FH, Als H, McAnulty GB. Linguistic profiles of dyslexics and good readers. Ann Dyslex. 1991; 41:221-45.
  43. Badian NA, Duffy FH, Als H, McAnulty GB. Linguistic profiles of dyslexic and good readers. Ann Dyslexia. 1991 Jan; 41(1):221-45.
  44. Badian NA, Duffy FH, Als H, McAnulty GB. Linguistic profiles of dyslexics and good readers. Presented at the Orton Dyslexia Society Conference. 1990.
  45. Albert MS, Duffy FH, McAnulty GB. Electrophysiologic comparisons between two groups of patients with Alzheimer's disease. Arch Neurol. 1990 Aug; 47(8):857-63.
  46. Duffy FH, Als H, McAnulty GB. Behavioral and electrophysiological evidence for gestational age effects in healthy preterm and fullterm infants studied two weeks after expected due date. Child Dev. 1990 Aug; 61(4):271-86.
  47. Duffy FH, Jones K, Bartels P, Albert M, McAnulty GB, Als H. Quantified neurophysiology with mapping: statistical inference, exploratory and confirmatory data analysis. Brain Topogr. 1990; 3(1):3-12.
  48. Duffy FH, McAnulty G. Neurophysiological heterogeneity and the definition of dyslexia: preliminary evidence for plasticity. Neuropsychologia. 1990; 28(6):555-71.
  49. Als H, Duffy FH, McAnulty GB. Neurobehavioral regulation disorder of prematurity. Infant Behavior and Development. 1990; 13:159.
  50. Badian NA, McAnulty GB, Duffy FH, Als H. Prediction of dyslexia in kindergarten boys. Ann Dyslex. 1990; 40:152-69.
  51. Badian NA, McAnulty GB, Duffy FH, Als H. Prediction of dyslexia in kindergarten boys. Ann Dyslexia. 1990 Jan; 40(1):152-69.
  52. Vasile RG, Duffy FH, McAnulty G, Bear D, Mooney JJ, Bloomingdale K, Serchuck LK, Schildkraut JJ. Abnormal visual evoked response in melancholia. Biol Psychiatry. 1989 Mar 15; 25(6):785-8.
  53. Als H, Duffy FH, McAnulty GB, Badian N. Continuity of neurobehavioral functioning in preterm and fullterm newborns. Bornstein M, Krasnegor N, editors. Stability and Continuity in Mental Development. 1989; 3-28.
  54. Duffy FH, Denckla MB, McAnulty GB, Holmes JA. Neurophysiological studies in dyslexia. Res Publ Assoc Res Nerv Ment Dis. 1988; 66:149-70.
  55. Duffy FH, McAnulty GB. Electrophysiological studies. Albert MS, Moss M, editors. Geriatric Neuropsychology. 1988; 262-89.
  56. Als H, Lawhon g, Gibes R, Duffy FH, McAnulty GB, Blickman JG. . Individualized behavioral and environmental care for the VLBW preterm infant at high risk for bronchopulmonary dysplasia and intraventricular hemorrhage. Study II: NICU outcome. New England Perinatal Society. 1988.
  57. Duffy FH, Denckla MB, McAnulty GB, Holmes JA. Neurophysiological studies in dyslexia. Plum F, editor. Language, Communication and the Brain. 1988; 66:149-70.
  58. Als H, Duffy FH, McAnulty GB. The APIB, an assessment of functional competence in preterm and fullterm newborns regardless of gestational age at birth: II. Infant Behav Dev. 1988; 11:319-31.
  59. Duffy FH, McAnulty GB, Albert MS. Brain mapping in normal aging and dementia. Bulletin of Clinical Neuroscience. 1988; 53:89-93.
  60. Als H, Duffy FH, McAnulty GB. Behavioral differences between preterm and fullterm and newborns as measured with the APIB System Scores: I. Infant Behav Dev. 1988; 11:305-18.
  61. Duffy FH, McAnulty G, Albert M, Durwen H, Weintraub S. Lecithin: absence of neurophysiologic effect in Alzheimer's disease by EEG topography. Neurology. 1987 Jun; 37(6):1015-9.
  62. Becker M, Kindlon DJ, Duffy FH, Jolesz FA, Als H, McAnulty GB, Rodier DW, Ploski C, Taeusch HW. Outcome 5-7 years after severe perinatal asphyxia (SPA) in term infants. Pediatric Research 21. 1987; 5.
  63. Als H, Lawhon G, Brown E, Gibes R, Duffy FH, McAnulty G, Blickman JG. Individualized behavioral and environmental care for the very low birth weight preterm infant at high risk for bronchopulmonary dysplasia: neonatal intensive care unit and developmental outcome. Pediatrics. 1986 Dec; 78(6):1123-32.
  64. Albert MS, Naeser MA, Duffy FH, McAnulty GB. CT and EEG Validators for Alzheimer's disease. Poon L, editor. Handbook of Clinical Memory Assessment. 1986; 514-30.
  65. Als H, Lawhon g, Gibes R, Duffy FH, McAnulty GB, Blickman JG. Individualized behavioral and environmental care for the VLBW preterm infant at high risk for bronchopulmonary dysplasia. Study I: NICU outcome. New England Perinatal Society. 1986.
  66. Morihisa JM, McAnulty GB. Structure and function: brain electrical activity mapping and computed tomography in schizophrenia. Biol Psychiatry. 1985 Jan; 20(1):3-19.
  67. Duffy FH, Albert MS, McAnulty G. Brain electrical activity in patients with presenile and senile dementia of the Alzheimer type. Ann Neurol. 1984 Oct; 16(4):439-48.
  68. Duffy FH, Albert MS, McAnulty G, Garvey AJ. Age-related differences in brain electrical activity of healthy subjects. Ann Neurol. 1984 Oct; 16(4):430-8.
  69. Duffy FH, McAnulty GB, Schacter SS. Brain electrical activity mapping. Geschwind N, Galaburda AM, editors. Cerebral Dominance: The Biological Foundations. 1984; 53-74.
  70. McAnulty GB, Hicks RE, Kinsbourne M. Pathological left-handedness and familial sinistrality in relation to degree of mental retardation. Brain Cogn. 1984; 3:349-56..
  71. Duffy FH, McAnulty GB. . Brain electrical activity mapping (BEAM): search for a physiological signature of dyslexia. Duffy FH, Geschwind N, editors. Dyslexia: A Neuroscientific Approach to Clinical Evaluation. 1984; 105-22.
  72. McAnulty GB, Schacter SC, Duffy FH. Brain electrical activity mapping and rhythm perception. Annals of Neurology. 1983; 14:143-144.
  73. Bradshaw GJ (McAnulty), Hicks RE, Rose B. Left visual field superiority in lexical discriminants. Brain Lang. 1979; 1:10-18..
  74. Bradshaw-McAnulty G. Neuropathology of Left-Handedness. Dissertations & Theses. 1979; (No. AAT7918777).
  75. Bradshaw-McAnulty, G. Neuropathology of Left-Handedness. 1979.
  76. Hicks RE, Bradshaw GJ (McAnulty), Kinsbourne M, Feigan D. Vocal-manual tradeoffs in hemispheric sharing of human performance control. J Mot Behav. 1978; 10:1-6.
  77. Mewes AU, Zöllei L, Hüppi PS, Als H, McAnulty GB, Inder TE, Wells WM, Warfield SK. Displacement of brain regions in preterm infants with non-synostotic dolichocephaly investigated by MRI. Neuroimage. 2007 Jul 15; 36(4):1074-85.
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